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| Number | Title | Issue Date |
| 8163806 | Controlled release of biologically active compounds from multi-armed oligomers The present invention relates to the discovery of biodegradable multi-armed oligomers wherein the end groups of these oligomers have been functionalized with biologically active molecules. The resultant multi-armed oligomers end-functionalized with biologically acti... | 04/24/2012 |
| 8158686 | Use of copolymers as solubilizers for slightly water-soluble compounds The use of copolymers obtained by free-radical polymerization of a mixture of i) 30 to 80% by weight of N-vinyllactam, ii) 10 to 50% by weight of vinyl acetate, and iii) 10 to 50% by weight of a po... | 04/17/2012 |
| 8148433 | Concentrated inverse latex, process for preparing it and industrial use thereof The invention relates to a composition in the form of a positive latex comprising a) between 50 wt. % and 80 wt. % of at least one cross-linked, branched, or linear organic polymer (P), b) between 5 wt. % and 10 wt. % of a water-in-oil (W/O) emulsifying system (S | 04/03/2012 |
| 8119698 | Sunscreen formula vanishing cream A cosmetic composition is provided which is a vanishing cream structured with 0.5 to 50% by weight of C12-C20 fatty acid, 0.1 to 20% by weight of C12-C20 fatty acid salt and hydrophilic composite particles with organic sun... | 02/21/2012 |
| 8084427 | Subcutaneous implants containing a degradation-resistant polylactide polymer The present invention refers to compositions comprising a LH-RH-analogue and/or pharmaceutically acceptable salts thereof in a low-dose and a degradation-resistant polylactide suitable for the preparation of subcutaneous implants. Sterilization of the polylactide vi... | 12/27/2011 |
| 8026285 | Control release of biologically active compounds from multi-armed oligomers The present invention relates to the discovery of biodegradable multi-armed oligomers wherein the end groups of these oligomers have been functionalized with biologically active molecules. The resultant multi-armed oligomers end-functionalized with biologically acti... | 09/27/2011 |
| 8013021 | Hydrocarbon-terminated polyether-polyamide block copolymer and uses thereof A composition comprising (a) a resin composition comprising a block copolymer of the formula hydrocarbon-polyether-polyamide-polyether-hydrocarbon; and (b) a polar liquid. The block copolymer may be prepared by a process comprising reacting together reactants compri... | 09/06/2011 |
| 7960439 | Environmentally sensitive foldable oligomers The invention relates to oligomers of cholic acid, cholate derivatives and amino acids called “foldamers” that undergo conformational changes in response to changes in temperature, solvent polarity, small molecules, metal ions, and pH. The foldamers can be used ... | 06/14/2011 |
| 7671095 | Films and particles Described herein are compounds and processes that can be used to prepare polymer-based films, particles, gels and related compositions, and processes for delivery of agents, and other uses. ... | 03/02/2010 |
| 7629388 | Synthesis and characterization of biodegradable cationic poly(propylene fumarate-co-ethylene glycol) copolymer hydrogels modified with agmatine for enhanced cell adhesion A cross-linkable monomer comprises a fumaric acid functional group having a first end and a second end, a first spacer group affixed to said first end and comprising at least repeating unit, a first terminal group affixed to said first spacer group, a second spacer ... | 12/08/2009 |
| 7491749 | At least one polyamide polymer in a cosmetic composition comprising at least one solid substance having a melting point of 45 degrees C. or greater Cosmetic compositions comprising at least one structuring polymer chosen from polymers of following formula (I): in which n denotes a number of amide units, such that the number of ester groups represents from 10% to 50% of... | 02/17/2009 |
| 7482381 | Artificial muscle hydrogel blends reversibly electroactuated near neutral pH, implantable actuating devices, and methods using the same A novel artificial muscle material and miniature valves and micropumps made therefrom are provided. The artificial muscle material bends reversibly when electroactuated by applying low voltage, in a wide pH range, even at that of physiological pH, and works without ... | 01/27/2009 |
| 7435790 | Dihydroxypropyl cysteine peptide and agent containing this peptide The invention relates to a S-(2,3-dihydroxypropyl)-cysteine peptide which has two long-chain fatty acids bonded in the form of esters at the dihydroxypropyl group, and which has the following sequence: DhcGN NDE SNI SFK EK. The invention relat... | 10/14/2008 |
| 7425581 | Temperature sensitive polymers The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (N-(2-hydroxypropyl)methacrylamide mono/di-lactate) interpolymers. Another aspect of this invention is the applicati... | 09/16/2008 |
| 7419687 | Delivery vehicle for silver ions A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of physiologically inert beads bearing a tissue cauterizing amount of a silver ion source. Preferably the beads ar... | 09/02/2008 |
| 7393840 | Formulation based on heparin, glycosaminoglycan or heparinoid, use of the formulation and the formulation base The present invention relates to formulations based on at least one heparin, glycosaminoglycan or heparinoid and on a formulation base with a lipid component and a polymer component. The use of this formulation as drug form for oral administration of at least one he... | 07/01/2008 |
| 7384984 | Reactive hydrophilic oligomers Hydrophilic compositions are described, which are prepared from a first component oligomer containing pendent hydrophilic groups and pendent reactive functional groups capable of reaction at effective rates (at normal processing temperatures), with a co-reactive sec... | 06/10/2008 |
| 7381422 | Method for producing sterile polynucleotide based medicaments The present invention relates to a novel method for producing formulations comprising a polynucleotide, block copolymer and cationic surfactant. The formulations produced by the current method are suitable for use in polynucleotide based medicaments. A suitable meth... | 06/03/2008 |
| 7381418 | Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent An implantable or insertable medical device which comprises (a) a therapeutic agent and (b) a polymeric release region that controls the release of the therapeutic agent upon administration to a patient. The polymeric release region comprises a radiation-crosslinked... | 06/03/2008 |
| 7381751 | Antimicrobial composition for medical articles An antimicrobial composition is formed from about 5 to about 25 wt % of an antimicrobial formulation and about 75 to about 95 wt % of a silicone resin. The antimicrobial formulation is formed from about 60 to about 95 wt % of an antimicrobial material, about 1 to ab... | 06/03/2008 |
| 7364752 | Solid dispersion pharamaceutical formulations A pharmaceutical composition is disclosed which comprises a solid dispersion of an HIV protease inhibitor in a water soluble carrier, such as PEG, having enhanced bioavailability and improved dissolution properties. The solid dispersion may optionally be encapsulate... | 04/29/2008 |
| 7357949 | Encapsulated inorganic antimicrobial additive for controlled release The invention relates to a microcapsule comprising an inorganic antimicrobial agent coated with a hydrophilic polymer. The hydrophilic polymer is able to absorb sufficient water as to enable the action of the encapsulated antimicrobial agent. These microcapsules are... | 04/15/2008 |
| 7351787 | Process for the preparation of activated polyethylene glycols A process for preparing activated polyethylene glycols is disclosed. In some embodiments, the process includes reacting a molten polyethylene glycol with an activator. In other embodiments, the process includes reacting a polyethylene glycol with an activator in the... | 04/01/2008 |
| 7348364 | Segmented copolyesters as compliant, absorbable coatings and sealants for vascular devices Disclosed are absorbable sealants or coatings for biomedical devices which are formulated from a segmented copolyester having a molecular weight of more than 5 kDa, a glass transition temperature of less than 35° C., and low degree of crystallinity evidenced by a h... | 03/25/2008 |
| 7342047 | Crosslinkable hydrophilic materials from reactive oligomers having pendent unsaturated groups The present invention provides cross linkable compositions useful in the preparation of hydrophilic gels, and are prepared from obligers having pendent hydrophilic ploy(alkenylene oxide) groups, and pendent pulverizable functional groups, and cross linked by polyfun... | 03/11/2008 |
| 7335795 | Crosslinked amine polymers The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides polymeric and pharmaceutical compositions comprising crosslinked amine polymers. Methods of use of the polymeric and pharmaceutical com... | 02/26/2008 |
| 7335675 | Aqueous suspension formulation for foliar application fungicide The present invention provides an aqueous suspension formulation containing (RS)-N-[2-(1,3-dimethylbutyl)thiophene-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide and having high rain resistance and stable residual effectiveness. A aqueous suspensi... | 02/26/2008 |
| 7332527 | Cross-linked ionic core micelles The present invention provides polymer micelles with cross-linked ionic cores as delivery vehicles for therapeutics, diagnostics, nucleic acids, proteins, small molecules and the like. The present invention provides additionally methods of synthesis and uses for suc... | 02/19/2008 |
| 7328756 | Settable fluids comprising particle-size distribution-adjusting agents and methods of use Settable fluids comprising particle-size distribution-adjusting agents, and methods of using such settable fluids in subterranean and surface applications are provided. In certain exemplary embodiments, the settable fluid comprises a cement, a set retarder, and a pa... | 02/12/2008 |
| 7326426 | Compositions and medical devices utilizing bioabsorbable liquid polymers The present invention is directed to medical devices and pharmaceutical compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid pol... | 02/05/2008 |
| 7288271 | Chlorogenic acid and an analog thereof for immune system stimulation The present invention relates to a preparation for stimulating or enhancing an immune system comprising one or more agents that stimulate T-lymphocytes in vivo. Such a preparation can be sued in the prophylaxis and/or treatment of a medical condition. The invention ... | 10/30/2007 |
| 7285255 | Deodorizing and sanitizing employing a wicking device A device and method for sanitizing and deodorizing including the selective transportation of a sanitizing composition by the capillary action of a wick to an acidic composition which may be held in a reservoir, or which also may be selectively transported through th... | 10/23/2007 |
| 7273567 | Energy-activated compositions for controlled sustained release of a gas A composition for energy-controlled generation and release of at least one gas, which includes an energy-activated catalyst capable of being activated by electromagnetic energy, and a solid or a liquid containing anions capable of being oxidized by the activated cat... | 09/25/2007 |
| 7261771 | Method of controlling the viscosity of a cementitious mixture using oppositely-charged polyelectrolytes A process for increasing the viscosity of an aqueous cementitious mixture during its working state by mixing oppositely-charge polyelectrolytes into the cementitious mixture. ... | 08/28/2007 |
| 7255870 | Composition containing a semicrystalline polymer, uses thereof, and method for making A composition containing an aqueous phase dispersed in an oily phase, at least one emulsifier with an HLB value ranging from 1 to 8, at least one organic powder, and, in the oily phase at least one semicrystalline polymer with organic structure that is solid at room... | 08/14/2007 |
| 7252838 | Drug releasing elastic band and method A ligating band according to the present invention comprises an elastomeric layer and an inner drug releasing layer. The inner drug releasing layer includes a therapeutic agent, for example a chemotherapeutic agent for treating a mucosa, polyp or other growth. A lig... | 08/07/2007 |
| 7244797 | Organic domain/inorganic domain complex materials and use thereof Disclosed are an organic domain/inorganic domain hybrid material comprising an organic domain comprising at least one water-soluble organic polymer having anionic and/or cationic functional groups, and an inorganic domain, the organic and inorganic domains being che... | 07/17/2007 |
| 7243788 | Package for segregating and mixing substances The present invention relates to a package that includes an enclosure having a first substance and a second substance within the enclosure. The package further includes a plastic zipper which segregates the first substance from the second substance within the enclos... | 07/17/2007 |
| 7241455 | Implantable or insertable medical devices containing radiation-crosslinked polymer for controlled delivery of a therapeutic agent An implantable or insertable medical device which comprises (a) a therapeutic agent and (b) a polymeric release region that controls the release of the therapeutic agent upon administration to a patient. The polymeric release region comprises a radiation-crosslinked... | 07/10/2007 |
| RE39713 | Polymerizable biodegradable polymers including carbonate or dioxanone linkages Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and methods of preparation and use thereof are described. The macromers a... | 07/03/2007 |
