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| Number | Title | Issue Date |
| 8008354 | Death receptor sensitizing compounds and methods of use therefor Methods of identifying death receptor sensitizing compounds and methods of using death receptor sensitizing compounds are provided. ... | 08/30/2011 |
| 7842730 | Medical emulsion of perfluororganic compounds and method for the production thereof Medicine, in particular medications for treating blood losses, hypoxic and ishemic states, for improving a blood oxygen supply and for preserving isolated perfused organs and tissues. The inventive medical emulsion of perfluororganic compounds includes rapidly excre... | 11/30/2010 |
| 7378449 | Poly(bromoaryl)alkane additives and methods for their preparation and use An additive mixture useful as a flame retardant is described. The mixture is comprised of (i) a poly(bromophenyl)alkane having in the molecule in the range of 13 to 60 carbon atoms and in the range of two to four aryl groups and (ii) a poly(bromophenyl)bromoalkane h... | 05/27/2008 |
| 7371888 | α-(Trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl)-trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetic agents Compounds having a formula: or a pharmaceutically acceptable salt or prodrug thereof, are provided, and are useful for the treatment of metabolic disorders. ... | 05/13/2008 |
| 7371714 | Chemical agent decontamination composition comprising a perfluorinated alkyl bromide A composition and methods of use for the decontamination of chemical agents, including chemical warfare agents. The decontamination composition is nontoxic, nonflammable and non-corrosive and includes an effective amount of a perfluorinated alkyl bromide or reactive... | 05/13/2008 |
| 6743825 | Poly(bromoaryl)alkane additives and methods for their preparation and use An additive mixture useful as a flame retardant is described. The mixture is comprised of (i) a poly(bromophenyl)alkane having in the molecule in the range of 13 to 60 carbon atoms and in the range of two to four aryl groups and (ii) a poly(bromophenyl)bromoalkane h... | 06/01/2004 |
| 6562872 | Emulsion of perfluoroorganic compounds for medical purposes, a process for the preparation thereof and methods for treating and preventing diseases with the use thereof An emulsion of perfluoroorganic compounds (PFOC) comprises a rapidly eliminable perfluorocarbon (PFC) and a slowly eliminable perfluorinated cyclic tertiary amine, perfluoro-N-4-(methylcyclohexyl)-piperidine and additionally comprises not less then three ... | 05/13/2003 |
| 6423330 | Pesticidal composition and method A mammalian pesticidal composition, and in particular a pesticidal composition for the control of insectivores, in which a pesticidal agent comprising one or more low molecular weight halogenated hydrocarbons, and in particular bromoform, is provided in m... | 07/23/2002 |
| 6204296 | Patient oxygenation using stabilized fluorocarbon emulsions Storage stable fluorocarbon emulsions having a continuous aqueous phase and a discontinuous fluorocarbon phase, in which the fluorocarbon phase comprises a major amount of a first fluorocarbon or fluorocarbon mixture, and a minor amount of a second fluoro... | 03/20/2001 |
| 6030620 | Skin care compositions containing an organic extract of chick pea Organic chick pea extracts are phytoestrogens, if present in an amount such as to provide an estrogenic activity equivalent to at least 1 nM of estradiol. Cosmetic compositions containing organic chick pea extracts are useful in improving the appearance o... | 02/29/2000 |
| 6028117 | Microemulsion insect control compositions Disclosed herein are microemulsion insecticides that do not contain conventional actives. The microemulsion form permits insects to be killed by an oil/surfactant combination.... | 02/22/2000 |
| 5997874 | Dihydrophenanthrene The present invention relates to a class of dihydrophenanthrene which are isolated from Calanthe discolor Lindl. and derivatives thereof.... | 12/07/1999 |
| 5955439 | Pharmaceutical aerosol containing at least one sugar This invention relates to aerosol formulations of use for the administration of medicaments by inhalation and in particular to a pharmaceutical aerosol formulation which comprises (a) particulate medicament; (b) at least one sugar; and (c) a fluorocarbon ... | 09/21/1999 |
| 5941243 | Apparatus and method for ethyl chloride topical anesthesia Apparatus for topical anesthesia by evaporative cooling with ethyl chloride (chloroethane) constitutes a container holding liquid ethyl chloride under pressure. A valve attached to the container hermetically seals the container in a first mode of operatio... | 08/24/1999 |
| 5914352 | Methods for the use of stabilized fluorocarbon emulsions Storage stable fluorocarbon emulsions having a continuous aqueous phase and a discontinuous fluorocarbon phase, in which the fluorocarbon phase comprises a major amount of a first fluorocarbon or fluorocarbon mixture, and a minor amount of a second fluoro... | 06/22/1999 |
| 5874481 | Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents A thermodynamically stable molecular solution providing enhanced bioavailability for lipophilic pharmaceutical agents, comprising a liquid carrier comprising one or more physiologically acceptable lipophilic fluorochemicals, and a pharmaceutically effecti... | 02/23/1999 |
| 5874113 | Shelf life improvement for ethylene oxide sterilant mixes A method of increasing the shelf life of a sterilant mixture of ethylene oxide and one or more halocarbons when the mixture is in contact with iron oxide on the surface of a storage vessel. Sufficient carbon dioxide is added to the mixture to reduce the r... | 02/23/1999 |
| 5785950 | Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of making and using them This invention relates to compositions comprising highly fluorinated, chloro-substituted, non-cyclic organic compounds having 7 to 9 carbon atoms and to processes of making and using them. More particularly, this invention relates to emulsions comprising ... | 07/28/1998 |
| 5635538 | Fluorocarbon emulsions with reduced pulmonary gas-trapping properties A fluorocarbon emulsion which exhibits reduced pulmonary gas-trapping properties in species-sensitive laboratory animals is disclosed. Additionally, the fluorocarbon component(s) exhibit short organ retention time(s). The emulsion includes an aqueous phas... | 06/03/1997 |
| 5597809 | Treatment of optic neuritis Methods of treating optic neuritis comprising administering a protective agent which inhibits glutamate-mediated retinal cell damage to a mammal at risk of developing optic neuritis.... | 01/28/1997 |
| 5578292 | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof One can impart outstanding resistance against collapse under pressure to gas-filled microvesicle used as contrast agents in ultrasonic echography by using as fillers gases whose solubility in water, expressed in liter of gas by liter of water under standa... | 11/26/1996 |
| 5573751 | Persistent gaseous bubbles as ultrasound contrast media Disclosed herein are agents for enhancing the contrast in an ultrasound image. These agents are extremely small bubbles, or "microbubbles," comprised of specially selected gases. The microbubbles described herein exhibit long life spans in solution and ma... | 11/12/1996 |
| 5558854 | Ultrasound contrast media comprising perfluoropentane and perfluorohexane gas Ultrasound contrast media comprising gaseous perfluoropentane and gaseous perfluorohexane are disclosed.... | 09/24/1996 |
| 5480914 | Nonaqueous thixotropic drug delivery suspensions and methods of their use Nonaqueous thixotropic drug delivery vehicles for use in aqueous physiological systems are disclosed comprising a substantially homogeneous dispersion of at least one suspending aid in a nonaqueous perfluorocarbon or fluorinated silicone liquid carrier. P... | 01/02/1996 |
| 5407962 | Emulsions of highly fluorinated organic compounds for chemotherapy Improved emulsions of highly fluorinated organic compounds. The emulsions comprise a highly fluorinated organic compound, an oil, that is not substantially surface active and not significantly water soluble, and a surfactant. They are characterized by a w... | 04/18/1995 |
| 5403575 | Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them This invention relates to compositions comprising highly fluorinated, chloro-substituted, non-cyclic organic compounds having 7 to 9 carbon atoms and to processes of making and using them. More particularly, this invention relates to emulsions comprising ... | 04/04/1995 |
| 5393513 | Stable, highly concentrated fluoro carbon emulsions A non-toxic, brominated perfluorocarbon emulsion for internal and intravenous use in animals (including humans) is disclosed, for use as an oxygen transport medium and as a contrast enhancement medium capable of facilitating the detection of tumors and ot... | 02/28/1995 |
| 5393524 | Methods for selecting and using gases as ultrasound contrast media Disclosed herein are agents for enhancing the contrast in an ultrasound image. These agents are extremely small bubbles, or "microbubbles," comprised of specially selected gases. The microbubbles described herein exhibit long life spans in solution and ma... | 02/28/1995 |
| 5376333 | Ethylene oxide-carrier gas compositions having improved flammability suppressant characteristics Compositions of ethylene oxide and monochlorotetrafluoroethane which are useful as sterilizing agents. These novel compositions are environmentally acceptable, possess improved flammability suppressant characteristics, and are capable of maintaining a gre... | 12/27/1994 |
| 5350571 | Emulsions of highly fluorinated organic compounds Improved emulsions of highly fluorinated organic compounds. The emulsions comprise a highly fluorinated organic compound, an oil, that is not substantially surface active and not significantly water soluble, and a surfactant. They are characterized by a w... | 09/27/1994 |
| 5244924 | Diluent for perfluorocarbons employed for retinal unfolding (unfolding PFCL) and method of treatment A diluent for perfluorocarbons used for retinal unfolding (unfolding PFCL), consisting of a perfluorocarbon (diluent PFCL), which has a low viscosity and is volatile at room temperature, with a boiling point between body temperature (about 38° C.) and 10... | 09/14/1993 |
| 5118676 | Penetration enhancers for transdermal delivery of systemic agents This invention relates to a method for administering systemically active agents including therapeutic agents through the skin or mucosal membranes of humans and animals and into the blood stream in a transdermal device or formulation comprising topically ... | 06/02/1992 |
| 5080885 | Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport A non-toxic, brominated perfluorocarbon emulsion for internal and intravenous use in animals (including humans) is disclosed, for use as an oxygen transport medium and as a contrast enhancement medium capable of facilitating the detection of tumors and ot... | 01/14/1992 |
| 4996041 | Method for introducing oxygen-17 into tissue for imaging in a magnetic resonance imaging system A diagnostic imaging agent is provided for use in conjunction with a magnetic resonance imaging system for the imaging of spacial oxygen distribution in tissue. The imaging agent is comprised of a complex of oxygen-17, a biologically acceptable liquid car... | 02/26/1991 |
| 4895876 | Concentrated stable fluorochemical aqueous emulsions containing triglycerides A stable concentrated aqueous emulsion of perfluorochemical, a phospholipid and a triglyceride of fatty acids has been demonstrated which has enhanced stability, diminished particle size and heightened tolerance by biological systems. The emulsion has uti... | 01/23/1990 |
| 4775522 | NMR compositions for indirectly detecting a dissolved gas in an animal A novel and improved method to detect and/or measure indirectly at least one gas, particularly dissolved gases, of an animal employing nuclear magnetic resonance techniques (NMR). The method examines an NMR spectrum to determine chemical shift relaxation ... | 10/04/1988 |
| 4216233 | Method for treatment of skin burns in mammals A method for treating skin burns in mammals where hot, molten organic substances have been deposited on, and are adhering to and aggravating, burned skin areas includes quickly but gently applying sufficient volatile cooling solvent to the affected areas ... | 08/05/1980 |
| 4110474 | Tetramethylpentane blood substitutes Perfluorination of 2,2,4,4-tetramethylpentane by direct fluorination with F2 or like reagents at low temperature, using inert gaseous diluents, yields a mixture of perfluoro 2,2,4,4-tetramethylpentane and 3-hydro-nona-decafluoro 2,2,4,4-tetrame... | 08/29/1978 |