Did You Know...
...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 8106099 | Combination of phenylcarboxamides with blockers of the IKr channel and their use for the treatment of atrial arrhythmias The invention relates to the combination of one or more IKr channel blockers and of one or more Kv1.5 blockers, in particular phenyl-carboxamides of the formula Ia or Ib or pharmaceutically tolerable salts thereo... | 01/31/2012 |
| 7399821 | Alkylated poly(allylamine) polymers and methods of use The invention relates to a method for removing bile salts from a patient in need thereof and compositions useful in the method. The method comprises administering to the patient a therapeutically effective amount of a salt of an alkylated and crosslinked polymer. Th... | 07/15/2008 |
| 7393825 | Microdose therapy Methods for treating vascular conditions associated with localized imbalance in vascular tone, which are hypothesized to be largely due to elevated endothelin (ET) are provided. The methods involve administration of nitric oxide (NO), agents which are able to provid... | 07/01/2008 |
| 7372350 | Electromagnetic relay An electromagnetic relay is provided which is small in size and is capable of controlling two circuits of an ordinarily-open contact, which has a large current-carrying capacity and high interrupting capability, and which is excellent in resistance against shock and... | 05/13/2008 |
| 7326730 | Aminoadamantane derivatives as therapeutic agents The present invention provides novel aminoadamantane derivatives, methods of making the derivatives, compositions including the novel aminoadamantane derivatives, and methods for the treatment and prevention of neurological diseases using the derivatives and composi... | 02/05/2008 |
| 7288535 | Methods and compositions for stimulating bone growth using nitric oxide releasing bisphosphonate conjugates The invention relates to compositions and methods for use in treating skeletal system disorders in a vertebrate at risk for bone loss, and in treating conditions that are characterized by the need for bone growth, in treating fractures, and in treating cartilage dis... | 10/30/2007 |
| 7261880 | Methods of treating Syndrome X with aliphatic polyamines The invention relates to a method for treating Syndrome X, or inhibiting the onset of symptoms of Syndrome X in a patient, and includes administering a therapeutically effective amount of a salt of at least one alkylated and cross-linked polymer, or a copolymer ther... | 08/28/2007 |
| 7189761 | Nitric oxide donor composition and method for treatment of anal disorders A pharmaceutical composition contains a nitric oxide donor and advantageously an optional corticosteroid and/or topical anesthetic. The composition is useful in a method for treating anal disorders such as anal fissure, anal ulcer, hemorrhoidal disease, levator spas... | 03/13/2007 |
| 7157500 | Nitrosylation of protein SH groups and amino acid residues as a therapeutic modality Nitrosylation of proteins and amino acid groups enables selective regulation of protein function, and also endows the proteins and amino acids with additional smooth muscle relaxant and platelet inhibitory capabilities. Thus, the invention relates to novel compounds... | 01/02/2007 |
| 7148259 | Antibacterial agents Hydroxyamidines and related compounds are provided which are suitable as antibacterial agents. ... | 12/12/2006 |
| 7086532 | Titration/compliance pack with increasing doses A titration package and method for enabling compliance with a regime of changing dosage of medication over a period of time includes a backing having an array of receivers with the array including a plurality of columns and a plurality of rows. A plurality of sets o... | 08/08/2006 |
| 7087654 | Ion exchange and electrochemical methods and devices employing one-step quaternized and polymerized anion selective polymers The invention provides ion exchange and electrochemical methods and devices employing anion exchange polymers produced by substantially simultaneous quaternization and polymerization reactions. Anion selective polymers are produced in accordance with the invention b... | 08/08/2006 |
| 7053074 | Prevention of ovarian cancer by administration of a Vitamin D compound The present invention relates to methods for preventing the development of epithelial ovarian cancer by administering a Vitamin D compound in an amount capable of increasing apoptosis in non-neoplastic ovarian epithelial cells of the female subject. ... | 05/30/2006 |
| 7048917 | Fat-binding polymers The present invention relates to a method for treating obesity, a method for reducing the absorption of dietary fat, and a method for treating hypertriglyceridemia in a patient and to particular polymers for use in the methods or in a manufacture of a medicament. Th... | 05/23/2006 |
| 6977250 | Prevention of ovarian cancer by administration of progestin products The present invention relates to methods for preventing the development of epithelial ovarian cancer by administering progestin products, either alone or in combination with other agents such as estrogen products. ... | 12/20/2005 |
| 6930113 | Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use The present invention describes novel nitrosated and/or nitrosylated phosphodiesterase inhibitors, and novel compositions containing at least one nitrosated and/or nitrosylated phosphodiesterase inhibitor, and, optionally, one or more compounds that donate, transfer... | 08/16/2005 |
| 6908609 | In vivo use of water absorbent polymers The subject invention is a method and material for removing fluid from the intestinal tract of a host and may be useful in treating animals or human patients suffering from fluid overload states. In one embodiment, the subject method involves ingesting an entericall... | 06/21/2005 |
| 6903100 | USE OF REGULARLY SCHEDULED HIGH DOSE INTRAVENOUS METHOTREXATE THERAPY, WITH INTERIM ADMINISTRATION OF IMMUNOMODULATORY AGENTS, TO TREAT MULTIPLE SCLEROSIS AND OTHER DISEASES OF THE CENTRAL NERVOUS SYSTEM The present invention is directed to the treatment of multiple sclerosis by periodically administering a high dose of methotrexate at a level sufficiently high to cross the blood brain barrier. The methotrexate administration is accompanied by leucovorin rescue of t... | 06/07/2005 |
| 6844320 | Treatment of preeclampsia, toxemia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor Preeclampsia and preterm labor in a pregnant female mammal are treated by administering thereto a combination of a progestin and a nitric oxide synthase substrate, a nitric oxide donor or both, optionally in further combination with one or more of a cyclooxygenase i... | 01/18/2005 |
| 6784254 | Process for removing bile salts from a patient and alkylated compositions therefor The invention relates to a method for removing bile salts from a patient in need thereof and compositions useful in the method. The method comprises administering to the patient a therapeutically effective amount of a salt of an alkylated and crosslinked polymer. Th... | 08/31/2004 |
| 6664297 | Methods for inhibition and dissolution of amyloidoses by administration of compositions comprising 2,4-dinitrophenol The inhibition of the formation and development of amyloidoses, as well as the dissolution of amyloidoses in organisms is claimed. Methods for the diagnosis of amyloidoses using aromatic and heteroaromatic compounds having at least one electron-withdrawin... | 12/16/2003 |
| 6562329 | Method of treating high plasma cholesterol levels A method prevents or treats diseases associated with high plasma cholesterol levels. In addition, this method reduces plasma cholesterol levels. The method comprises administering a lipase inhibitor, e.g. orlistat, and a pharmaceutically acceptable bile a... | 05/13/2003 |
| 6472425 | Methods for treating female sexual dysfunctions The present invention provides methods for treating female sexual dysfunctions by administering to a female individual a therapeutically effective amount of at least one compound that donates, transfers or releases nitrogen monoxide, that induces the prod... | 10/29/2002 |
| 6472390 | Use of therapeutic dosages for nitric oxide donors which do not significantly lower blood pressure or pulmonary artery pressure Patients with pathologic conditions involving constriction or proliferation of smooth muscle or disease associated with cysteine containing proteins, or who are at risk for such, are administered a therapeutically effective amount of a nitric oxide (NO) d... | 10/29/2002 |
| 6436996 | Modulation of nitric oxide production A method of treating cells that carry at least one APOE4 allele comprises increasing nitric oxide levels in the cells (e.g., by administering an exogenous source of nitric oxide to the cells) by an amount sufficient to combat the decrease of nitric oxide ... | 08/20/2002 |
| 6432413 | Functional improvements in Fahr disease The invention provides methods of treating diseases of the central and peripheral nervous systems that are associated with abnormal calcifications within the nervous system, such as Fahr disease. These methods involve administration of bisphosphonates, su... | 08/13/2002 |
| 6433026 | Process for removing bile salts from a patient and alkylated compositions therefor The invention relates to a method for removing bile salts from a patient in need thereof and compositions useful in the method. The method comprises administering to the patient a therapeutically effective amount of a salt of an alkylated and crosslinked ... | 08/13/2002 |
| 6342499 | Parasitic and saprophagous mite control in beneficial insects The present invention provides a method to control parasitic and saprophagous mites on beneficial insects such as honeybees via the application of a parasiticidally or saprophagouscidally effective amount of a mitochondrial electron transport inhibitor or... | 01/29/2002 |
| 6294583 | Methods of treating tardive dyskinesia and other movement disorders The present invention describes a novel treatment for movement disorders, including tardive dyskinesia, tic disorders, Tourette's syndrome, and blepharospasm, and other focal dystonias. The treatment of the present invention utilizes agents that simultane... | 09/25/2001 |
| 6287601 | Topical nitric oxide donor compositions Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID mixed in a lipid-based carrier are described. The applicati... | 09/11/2001 |
| 6277891 | Nitric oxide inhibits rhinovirus infection Nitric oxide generating compounds or compounds which induce in situ synthesis of nitric oxide can be used to inhibit rhinovirus infection. Nitric oxide has the ability to inhibit both viral replication as well as the synthesis of cytokines, in particular ... | 08/21/2001 |
| 6225355 | Process for removing bile salts from a patient and alkylated compositions therefor The invention relates to a method for removing bile salts from a patient in need thereof and compositions use full in the method. The method comprises administering to the patient a therapeutically effective amount of a salt of an alkylated and crosslinke... | 05/01/2001 |
| 6133320 | Treatment of osteoporosis and metabolic bone disorders with nitric oxide substrate and/or donors Primary and secondary osteoporosis in a female or a male mammal is treated by administering thereto a nitric oxide synthase substrate, a nitric oxide donor or both, optionally; in further combination with one or more of an estrogen, a progestin, an anabol... | 10/17/2000 |
| 6075044 | Heterocyclic derivatives as inhibitors of purine salvage phosphoribosyltransferases The use of certain heterocyclic derivatives for treating parasitic protozoa infections in mammals, in particular bovine trichomoniasis and giardiasis, is disclosed.... | 06/13/2000 |
| 6071876 | Method of preventing NMDA receptor complex-mediated neuronal damage Disclosed is a method for decreasing NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a nitroso-compound that generates nitric-oxide or related redox species, in a concentration effective to effect neuroprotection. Also di... | 06/06/2000 |
| 6066678 | Process for removing bile salts from a patient and alkylated compositions therefor The invention relates to a method for removing bile salts from a patient in need thereof and compositions useful in the method. The method comprises administering to the patient a therapeutically effective amount of an alkylated and crosslinked polymer. T... | 05/23/2000 |
| 6066649 | Drug for cardiovascular diseases The invention relates to a drug, which contains one or more inhibitors for the cGMP-stimulated phosphodiesterase (PDE II) together with conventional substrates and/or diluents. Preferably the drug contains erythro-9-(2-hydroxy-3-nonyl)-adenine or 2-o... | 05/23/2000 |
| 6060517 | Process for removing bile salts from a patient and compositions therefor A method for removing bile salts from a patient by ion exchange by administering to the patient a therapeutically effective amount of one or more highly crosslinked polymers characterized by a repeat unit having the formula ##STR1## or copolymer... | 05/09/2000 |
| 6045827 | Treatment of equine laminitis Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID mixed in a lipid-based carrier are described. The applicati... | 04/04/2000 |
| 5997874 | Dihydrophenanthrene The present invention relates to a class of dihydrophenanthrene which are isolated from Calanthe discolor Lindl. and derivatives thereof.... | 12/07/1999 |
