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Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 8415399 | Retrovirus-infection inhibitor An infection inhibitor of retrovirus, particularly human immunodeficiency virus, comprising, as an active ingredient, at least one compound selected from the group consisting of a compound represented by the formula (I) (GGA) or a salt thereof, a compound represente... | 04/09/2013 |
| 8293803 | Retinoid compounds and their use The invention relates to retinoid compounds of the formula (I): wherein V is a hydrophobic group; W is a non-polyenic linker; and X is a polar group compr... | 10/23/2012 |
| 8211946 | Pharmaceutical formulation The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophil... | 07/03/2012 |
| 8148431 | Osteogenesis promoter containing β-cryptoxanthin as the active ingredient It is intended to provide an osteogenesis promoter having a remarkable effect of positively promoting osteogenesis and thus preventing/treating bone diseases; a preventive/a remedy for bone diseases such as osteoporosis having both of an osteogenesis-promoting effec... | 04/03/2012 |
| 8030360 | Anti-wrinkle agent A medicament having an anti-wrinkle action, which comprises as an active ingredient a retinoid having a fundamental structure of a phenyl substituted carbamoyl benzoic acid or a phenyl substituted carboxamide benzoic acid (for example, 4-(3,5-bis(trimethylsilyl)phen... | 10/04/2011 |
| 7951845 | Composition and method of treating hearing loss A composition for treating hearing loss includes components that function through different biological mechanisms to provide an additive effect that is equal to or greater than a sum of the effect of the individual components. The composition includes a biologically... | 05/31/2011 |
| 7902260 | Medicament for preventive and/or therapeutic treatment of lower urinary tract symptom A medicament for preventive and/or therapeutic treatment of a lower urinary tract symptom caused by a lower urinary tract disorder, which comprises as an active ingredient a retinoid such as, for example, 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2 -naphthalenyl)ca... | 03/08/2011 |
| 7786175 | Anti-atherosclerosis composition containing carotenoids and method for inhibiting LDL oxidation An anti-atherosclerosis composition comprising a LDL-oxidation inhibiting effective amount of phytoene, phytofluene or mixtures thereof and a method for inhibiting the progression of atherosclerosis. ... | 08/31/2010 |
| 7781489 | Microemulsions of retinoids, and pharmaceutical compositions containing them Disclosed are water-in-oil (W/O) microemulsions containing as active ingredient a retinoid, a phospholipid emulsifier, and possibly hyaluronic acid or salts thereof. ... | 08/24/2010 |
| 7709536 | Pharmaceutical formulation The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophil... | 05/04/2010 |
| 7605185 | Treatment of arrhythmia by retinoids affecting signal transduction A polypeptide is identified as being functionally included in a signal transduction pathway having a biological effect. Contemplated polypeptides are different from a retinoic acid receptor, a retinoid X receptor, or a cellular retinoic acid binding protein, however... | 10/20/2009 |
| 7435725 | Oral compositions and methods for prevention, reduction and treatment of radiation injury An oral composition for the prevention, reduction or treatment of radiation injury including one or more compounds that regulates cell differentiation and/or cell proliferation, and one or more antioxidants, optionally formulated in a pharmaceutically acceptable car... | 10/14/2008 |
| 7432307 | Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein also provide for the screening of modulators of retinol-RBP-TTR complex... | 10/07/2008 |
| 7390509 | Compositions and methods for nutrition supplementation The present invention relates to compositions comprising various vitamins and minerals and methods for using these compositions for nutritional supplementation in, for example, pregnant or lactating subjects. ... | 06/24/2008 |
| 7374772 | Topical antifungal treatment The present invention is a topical skin preparation for treatment of fungal infections of the skin and nails. The preparation comprises triacetin in combination with an antifungal agent. In a preferred form, the preparation further comprises, a fatty acid source suc... | 05/20/2008 |
| 7351746 | Anti-atherosclerosis composition containing carotenoids and method for inhibiting LDL oxidation An anti-atherosclerosis composition comprising a LDL-oxidation inhibiting effective amount of phytoene, phytofluene or mixtures thereof and a method for inhibiting the progression of atherosclerosis. ... | 04/01/2008 |
| 7335384 | Nutrient compositions for the treatment and prevention of inflammation and disorders associated therewith The present disclosure describes a novel composition for the treatment and/or prevention of neurogenic inflammation. Such composition is also useful in the treatment and/or prevention of disease states and conditions associated with neurogenic inflammation. Such dis... | 02/26/2008 |
| 7304038 | Therapeutic composition and method of supporting the immune system Disclosed is a therapeutic nutritional compound for treating and supporting the immune response in a mammal, particularly a human baby or child, and the treatment method. Additionally, the therapeutic nutritional compound can be used in conjunction with a vaccine or... | 12/04/2007 |
| 7294349 | Wrinkle cream An emulsion comprising: water; hydrophilic particles; and hydrophobic particles; wherein the hydrophilic and hydrophobic particles form shells encapsulating a gas that are suspended in the water, said shells comprising an external layer of hydrophilic particles and ... | 11/13/2007 |
| 7279180 | Stable emulsions and dry powders of mixtures of fat-soluble vitamins, their preparation and use The present invention relates to stable emulsions and dry powders of mixtures of fat-soluble vitamins, and to processes for their preparation and to their use. ... | 10/09/2007 |
| 7273606 | Solubilized CoQ-10 and carnitine The present invention is directed to compositions and methods of delivery of CoQ-10 and an amino acid solubilized in monoterpenes. Use of monoterpenes as dissolving agents, greatly effects the ability to incorporate greater amounts of bioactive CoQ-10 and the amino ... | 09/25/2007 |
| 7267830 | Composition and methods for inhibiting the progression macular degeneration and promoting healthy vision The present invention provides improved dietary supplements and methods for inhibiting the progression of macular degeneration and promoting healthy vision. The dietary supplements of the invention contain cobeadlets comprising vitamin E and carotenoids in the form ... | 09/11/2007 |
| 7262224 | Cosmetic rejuvenating and healing product, method of its manufacture and uses thereof A cosmetic composition is shown for rejuvenating the appearance of skin with reduced or minimal potential for skin irritation, in the form of a lotion or cream which includes as a major component aloe vera as well as vitamins A, B, C, D and E. ... | 08/28/2007 |
| 7259188 | Methods and pharmaceutical compositions for treatment of anti-estrogen resistant breast cancer using RXR modulators Methods and compositions for the treatment of anti-estrogen resistant breast cancer using retinoid compounds which are modulators of Retinoid X Receptors. ... | 08/21/2007 |
| 7253212 | Retinol derivative and cosmetic composition comprising the same The present invention relates to a novel retinol derivative and a cosmetic composition comprising the same, in particular, to a novel retinol derivative represented by the formula (I) exhibiting the effects from both L-ascorbic acid and retinol as well as being free... | 08/07/2007 |
| 7250445 | Anti-oxidant suppository for treating radiation proctopathy and other anorectal disorders A method for treating anorectal disorders, comprising a step of providing a suppository containing between 1000 and 500,000 IU of an antioxidant selected from the group of Vitamin A, Vitamin C, Vitamin E; and a step of placing the suppository within the rectal cavit... | 07/31/2007 |
| 7244749 | Compositions and methods for lowering plasma lipoprotein(a) and risk factors of cardiovascular diseases The present invention provides compositions and methods for lowering plasma Lp(a) levels in humans. The present invention provides compositions and methods for lowering the risk factors for cardiovascular diseases. Moreover, this invention provides therapeutic alter... | 07/17/2007 |
| 7244463 | enhanced animal food product The present invention advances prior art animal food products by providing an animal food product formulated with Garicinia mangostana L., or Mangosteen fruit, from the Mangosteen plant. The addition of Mangosteen to the animal food product of the present inv... | 07/17/2007 |
| 7241808 | Composition for treatment of skin and method for stabilizing the composition A composition for the treatment of skin comprises a carboxylated, acidic amino acid obtained by acidifying an acidic amino acid with a carboxylic acid. The resultant material, which is also referred to as a tricarboxylic acid or an amino fruit acid, has significant ... | 07/10/2007 |
| 7226610 | Compositions and methods for the treatment and prevention of disease in plants Non-toxic, naturally derived and economical compositions for treating and preventing bacterial or fungal disease in plants, especially citrus canker, wherein such compositions include various combinations of d-limonene, wax and monohydric alcohol are provided. Metho... | 06/05/2007 |
| 7223736 | Composition for the prevention and treatment of cachexia The present invention relates to methods and nutritional compositions for the prevention and treatment of cachexia and anorexia. The methods of the invention comprise administering a composition comprising effective amounts of ω-3 fatty acids such as alpha-linoleni... | 05/29/2007 |
| 7223397 | Potentiation of anti-CD38-Immunotoxin cytotoxicity The present invention is directed to the use of agents that induce high levels of cell surface molecules to provide targets for immunotoxins directed against the same cell surface molecules. A specific example is given in which all-trans-retinoic acid (RA) is used t... | 05/29/2007 |
| 7205007 | Peri-operative and peri-procedure nutritional supplementation The invention provides a nutritional supplement system and program for patients undergoing or who have undergone a surgical or other invasive or stressful procedure, or who have suffered an injury. This nutritional supplement for the peri-operative period is designe... | 04/17/2007 |
| 7196065 | Enteral formulation A formulation for enteral administration to a patient is disclosed. ... | 03/27/2007 |
| 7192583 | Methods for modulating bone mineralization Antibodies to a novel family of TGF-β binding proteins are disclosed, for use in methods of altering bone density and bone mineralization, which methods are applicable to the treatment of diseases including osteopenia and osteoporosis. ... | 03/20/2007 |
| 7186418 | Composition and use of RAR antagonists for promoting chondrogenesis The invention provides compositions comprising an RAR antagonist for promoting chondrogenesis and methods employing such compositions for treating cartilage and associated bone abnormalities resulting from injury or disease and for ex vivo tissue engineering. ... | 03/06/2007 |
| 7179841 | Stabilized ascorbic acid compositions and methods therefor The present invention relates to ascorbic acid single-phase solution compositions that provide enhanced stability, enhanced solubility and an enhanced photoprotective effect as compared to prior compositions. The compositions comprise L-ascorbic acid; a cinnamic aci... | 02/20/2007 |
| 7169819 | Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same A pharmaceutical composition for parenteral delivery, comprising a retinide such as fenretinide in combination with a solvent capable of dispersing or solubilizing the retinide. The solvent comprises an alcohol, such as ethanol, in combination with an alkoxylated ca... | 01/30/2007 |
| 7166642 | Use of cyclohexenone long-chain alcohol for treating neurodegenerative diseases A preventive and therapeutic drug for a neurodegenerative disease containing, as an active ingredient, a cyclohexenone long-chain alcohol compound represented by formula (1) wherein each of R1, R2, and R3 represents a hydrogen atom o... | 01/23/2007 |
| 7160550 | Cosmetic compositions A cosmetic composition having improved transfer resistance comprising: a) from about 0.1–60% by weight of trimethylated silica, b) from about 0.1–60% by weight of a volatile solvent having a viscosity of 0.5 to... | 01/09/2007 |
