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| Number | Title | Issue Date |
| 8003703 | Phenoxiacetic acid derivatives The invention relates to certain 2-substituted phenoxyacetic acid derivatives of formula (I), in which the variables are as defined in the claims, useful in the treatment of diseases or conditions in which modulation of the CRTh2 receptor is beneficial, such as asth... | 08/23/2011 |
| 7943670 | Liquid formulations of ractopamine Described is a soluble stable liquid formulation, process for preparing, and a method of using the soluble stable liquid formulation comprising ractopamine or a physiologically acceptable salt thereof, a liquid nonionic cosolvent, and water. ... | 05/17/2011 |
| 7754773 | Composition and synthesis of new reagents for inhibition of HIV replication The present invention provides compounds and compositions for inhibiting Vif and methods for treating viral infection, e.g., HIV infection. ... | 07/13/2010 |
| 7687547 | Diphenyl ether antimicrobial compounds The present invention is directed to compounds having the formula: In the formula, A2 represents N or C—X1a—R1 and A4 represents N or C—X2bâ... | 03/30/2010 |
| 7566740 | Method of treating mucositis A method of treating mucositis in immunocompromised patients is disclosed which is based on contacting the affected area with an amount of composition which comprises triclosan and a cationic antibacterial agent in amounts which are effective to alleviate the sympto... | 07/28/2009 |
| 7473711 | Androgen modulators The present invention is directed to a class of 4-cyano-phenoxy derivatives of formula I and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate ... | 01/06/2009 |
| RE40246 | Method for the suppression of viral growth A method for suppressing undesired viral growth in a host which comprises administering to the host an effective amount of a compound of the formula: wherein R1, R2, R3 and R4 are indep... | 04/15/2008 |
| 7335659 | Substituted 10-aryl-11-benzo[]fluorenes and 7-aryl-5, 6-dihydro-benzo[]anthracenes for selective effects on estrogen receptors This invention provides a compound, or its possible salt, having the formula, wherein: Re and ′Re are OH, optionally independently etherified or esterified; Z is —CH2CH2— or... | 02/26/2008 |
| 7318930 | Control methods for boring bark beetles A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described. Additional tests have shown that beetles will not infest a tree which... | 01/15/2008 |
| 7307071 | RAF-MEK-ERK pathway inhibitors to treat cancer Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia, and which cancer is preferably resistant to the inhibition of the Bc... | 12/11/2007 |
| 7232845 | Active substance combinations comprising insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 06/19/2007 |
| 7220783 | Para-terphenyl compounds The present invention provides a selective suppressor of the IgE production comprising a compound which suppresses the IgE production in a process from a differentiation of a mature B cell into an antibody-producing cell to the production of an antibody and which do... | 05/22/2007 |
| 7157419 | Growth factor binding molecules Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid sidechains. The growth factor binding molecules specifically bind various growt... | 01/02/2007 |
| 7109245 | Vasoconstrictor cannabinoid analogs Methods and compounds for reversing pathological vasodilation of blood vessels, for example vasodilation caused by activation of CB1-like receptors, by administering to a subject a therapeutically effective amount of a compound sufficient to induce vasoconstriction,... | 09/19/2006 |
| 7105577 | Antimicrobial method using a hydroxydiphenyl ether compound The present invention relates to the use of hydroxydiphenyl ether compounds as antimicrobially active substances, to certain new compounds of this type and to processes for the preparation of these compounds. ... | 09/12/2006 |
| 7101915 | P-terphenyl compounds The present invention provides a selective suppressor of the IgE production comprising a compound which suppresses the IgE production in a process from a differentiation of a mature B cell into an antibody-producing cell to the production of an antibody and which do... | 09/05/2006 |
| 7091233 | Active substance combinations comprising insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 08/15/2006 |
| 7074836 | Para-terphenyl compounds The present invention provides a selective suppressor of the IgE production comprising a compound which suppresses the IgE production in a process from a differentiation of a mature B cell into an antibody-producing cell to the production of an antibody and which do... | 07/11/2006 |
| 7056862 | Herbicide potentiators The invention provides an agricultural chemical enhancer and an agricultural chemical composition which are safely used for crops without any phytotoxicity, have a potency enhancing action on various agricultural chemicals and promote the growth of a plant body to b... | 06/06/2006 |
| 7041307 | Biocide-polyester concentrates and biocidal compositions prepared therefrom Concentrates of various classical biocides in a polyester carrier resin when incorporated into a substrate resin, preferably a polyolefin such as polypropylene or polyethylene, provide the substrate polymer which biocidal activity with superior resistance to discolo... | 05/09/2006 |
| 7030162 | Treatment of migraine headache The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs that are non-acidic or segregating the metoclopramide and NSAID, the... | 04/18/2006 |
| 7030985 | Colored transparent or translucent cosmetic composition The invention relates to a transparent or translucent colored cosmetic composition for making up the skin, lips and superficial body growths comprising a transparent or translucent cosmetic base and at least one coloring agent in an amount such that the transmission... | 04/18/2006 |
| 7001926 | Tubulin binding agents and corresponding prodrug constructs A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin... | 02/21/2006 |
| 6994866 | Combinations of active ingredients, which exhibit insecticidal and acaricidal properties The invention relates to novel active compound combinations having very good insecticidal and acaricidal properties and containing (a) cyclic ketoenols having the formula  in... | 02/07/2006 |
| 6984665 | Methods for the inhibition of atrophy or for treatment or prevention of atrophy-related symptoms in women This invention relates to a method for inhibition of skin atrophy, or epithelial or mucosal atrophy in women, or to a method for treatment or prevention of symptoms related to said atrophy, said method comprising administering to the woman an effective amount of the... | 01/10/2006 |
| 6956132 | Process for producing 2-phenylacetophenone derivatives and precursors therefor A process for producing 2-phenylacetophenone derivatives represented by the formula (I): (wherein X is an alkyl group or a haloalkyl group, and Y is a hydrogen atom, a halogen atom or an alkyl group which may be substi... | 10/18/2005 |
| 6949551 | Dihalopropene compounds, processes for their preparation, compositions comprising them and their use as pesticides Dihalopropene compounds, process for their preparation, compositions comprising them and their use as pesticides What is described are dihalopropene compounds of the formula (I) in which R1 and R... | 09/27/2005 |
| 6943197 | Topical administration of pharmacologically active bases in the treatment of inflammatory dermatoses Provided are methods and topical pharmaceutical formulations for the treatment of inflammatory dermatoses. The invention involves the topical administration of a pharmacologically active base in a formulation having a pH of about 7.5 to about 13.0, preferably about ... | 09/13/2005 |
| 6933321 | Antiandrogenic biphenyls Biphenyl derivatives are disclosed for use in the treatment of androgen-dependent diseases, such as prostate cancer, benign prostatic hyperplasia, precocious puberty, polycystic ovarian syndrome, acne, hirsutism, seborrhea, androgenic alopecia and premature male bal... | 08/23/2005 |
| 6855341 | Anti-viral compositions and methods of making and using the anti-viral compositions Disclosed are anti-viral compositions containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients), and a pharmaceutical carrier. Also disclosed are methods of treating lesionous symptoms of a viral infection involvi... | 02/15/2005 |
| 6835386 | Collar containing a novel gel formulation to control arthropod infestation of animals The present invention provides a device, preferably a collar or ear tag, capable of the controlled, sustained release of an effective amount of an active ingredient that can protect an animal against arthropod pests, comprising a reservoir containing a novel gel for... | 12/28/2004 |
| 6797728 | Use of intracellular calcium chelators to increase surfactant secretion in the lungs Pulmonary surfactant is required in order to reduce surface tension in the lungs so that less effort is needed to reinflate the lungs after exhalation. A number of diseases and conditions exist that disrupt the normal flow of surfactant secretion, resulting in respi... | 09/28/2004 |
| 6790868 | Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same Antimicrobial compounds, compositions containing the same, and methods of using of the same for reducing the presence of microorganisms on a substrate or in a fluid environment comprising an antimicrobial effective carrier and at least one antimicrobial compounds in... | 09/14/2004 |
| 6777444 | Method for regulation of gene expression in eukaryotic cells using nordihydroguaiaretic acid derivatives Use of nordihydroguaiaretic derivatives to suppress CDC-2 and survivin, stimulate apoptosis, and treat tumors. ... | 08/17/2004 |
| 6773702 | Use of combretastatin A4 and its prodrugs as an immune enhancing therapy A method of treating immune suppression in a warm-blooded animal bearing a tumor, by administering to the animal an amount of combretastatin A4 and/or a prodrug thereof effective to enhance immune responsiveness without causing vascular destruction. Immunotherapy tr... | 08/10/2004 |
| 6767923 | Benzhydryl derivatives Benzhydryl derivatives of the formula I, where the index and the variables are as defined below: X is oxygen or sulfur; R1, R3 are halogen, cyano, nitro, hydroxyl, mercapto, amino, alk... | 07/27/2004 |
| 6686371 | Non-steroidal, tetracylic compounds for estrogen-related treatments The invention provides non-steroidal estrogenic compounds with estrogenic and anti-estrogenic compounds effects for treatment of estrogen-deficiency related disorders, which compounds are having formula (I) wherein, one of Ra or Rb i... | 02/03/2004 |
| 6677383 | Hydroxylation activated prodrugs The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumor prodrugs and those which are specifically activated by the hydroxylation activity of the enzyme CYP1B1.... | 01/13/2004 |
| 6641800 | Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer soluble in the liquefied hydrofluoroalkane which is selected fr... | 11/04/2003 |
| 6635663 | Pesticidal emulsifiable concentrate The present invention provides a low-irritant pesticidal emulsifiable concentrate comprising (a) 1 to 60% by weight of at least one pesticidal active ingredient compound selected from the group consisting of pyriproxyfen and a pyrethroid compound, (b) 2 t... | 10/21/2003 |
