Did You Know...
...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.
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| Number | Title | Issue Date |
| 8013020 | 1-adamantyl chalcones for the treatment of proliferative disorders The present invention relates to the compounds of the general formula (I), a composition for and a method of treating breast cancer or other proliferative disorders in a subject using a compound of general formula [I], wher... | 09/06/2011 |
| 7977388 | Quinone derivative 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone for the treatment of muscular dystrophies Use of idebenone for the preparation of a medicament for the treating of a muscular dystrophy in particular for treating and/or preventing weakness and/or loss of skeletal muscle tissue and/or cardiomyopathy associated with a muscular dystrophy. ... | 07/12/2011 |
| 7919531 | 3,5-dihydroxy-2,4-cyclohexadienones and their derivatives, dietary compositions and fortified food containing them and their uses The present invention refers especially to 3,5-dihydroxy-2,4-cyclohexadienones of the general formula (I) wherein R1 and R2 are independently from each other C1-6-alkyl, C2-6-alkenyl or x-oxo-Cx-alkyl with x bei... | 04/05/2011 |
| 7364747 | Process and product for inhibiting or preventing bacterial infections The combination of a polymyxin composition and a hop composition produces unexpected and synergistic activity against gram positive bacteria. ... | 04/29/2008 |
| 7348363 | Method of controlling zoological and aquatic plant growth A method of controlling target aquatic microorganism pest populations by exposing the target population to an effective amount of an aquacidal compound. The aquacidal compounds are selected from the group consisting of quinones, anthraquinones, naphthalenediones, qu... | 03/25/2008 |
| 7335384 | Nutrient compositions for the treatment and prevention of inflammation and disorders associated therewith The present disclosure describes a novel composition for the treatment and/or prevention of neurogenic inflammation. Such composition is also useful in the treatment and/or prevention of disease states and conditions associated with neurogenic inflammation. Such dis... | 02/26/2008 |
| 7318428 | Paint ball gun having paint ball dispenser with threaded connector A paint ball gun is disclosed including a dispenser having a locking connector designed to lockingly engage a locking connector on a gun feed tube or one end of a hollow connecting member. ... | 01/15/2008 |
| 7312243 | Materials and methods for treatment of gastrointestinal disorders The subject invention pertains to materials and methods for the prevention and treatment of gastrointestinal diseases, including inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. Therapeutic compositions of the invention include composition... | 12/25/2007 |
| 7112698 | 4-(c2-6alkoxy)-substituted chalcones as therapeutic agents The present invention pertains to compounds of the following formula: (1) wherein: RALK is primary or secondary aliphatic saturated C2-6alkyl; each of RB2, RB3, RB4, and RB5 is independently —H, —... | 09/26/2006 |
| 7064124 | NF-κB inhibitor containing substituted benzoic acid derivative as active ingredient A NF-κB inhibitor represented by the following formula (I) is provided: ... | 06/20/2006 |
| 7026342 | Method for treating fibrotic diseases or other indications utilizing thiazole, oxazole and imidazole compounds Provided is a method of treating or ameliorating a number of indications in an animal, including a human, comprising administering an effective amount of a compound of the formula I or IA, wherein J is oxygen, sulfur, o... | 04/11/2006 |
| 7015252 | Compositions for lessening oxidative stress The present invention provides an antioxidative composition with high safety, which is capable of lessening oxidative stress due to active oxygen species, free radicals, or the like in vivo, thereby preventing the occurrence or worsening of a disease. It was confirm... | 03/21/2006 |
| 6949586 | Synergistic composition of trans-tetracos-15-enoic acid and Apocynin and method of treatment for hepatotoxicity The present invention relates to a synergistic hepatoprotective pharmaceutical composition comprising an effective amount of trans-tetracos-15-enoic acid (TCA) and Apocynin (APO), the present invention also relates to a method of treatment for hepatotoxicity in mamm... | 09/27/2005 |
| 6930207 | Trifluoroacetylalkyl-substituted phenyl, phenol and benzoyl compounds and related methods of treatment Novel and known trifluoroacetyl-substituted phenyl, phenol and benzoyl compounds for the treatment and/or inhibition of obesity and of concomitant and/or secondary diseases involved therewith, in particular metabolic syndrome and cardiovascular diseases. Novel trifl... | 08/16/2005 |
| 6906076 | Compounds and methods of use to treat infectious diseases The present invention concerns alkyl aryl carbonyl compounds that possess anti-infective activity. The compounds of the invention can be used to target specific nuclear localization signal, thereby blocking importation of specific proteins or molecular complex into ... | 06/14/2005 |
| 6822002 | Use of L-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use The use of L-carnitine and its alkanoyl devivatives, optionally in the form of a pharmaceutically acceptable salt, as osmotic agents in the preparation of solutions for medical use, particularly for peritoneal dialysis, is described. ... | 11/23/2004 |
| 6790463 | Uses of targeted oxidative therapeutic formulation in arteriosclerosis The use of a pharmaceutical formulation in treating coronary arteriosclerosis and a two-component pharmaceutical formulation. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by a... | 09/14/2004 |
| 6677376 | Non-peptidic cyclophilin binding compounds and their use The invention relates to non-peptidic compounds that possess bioactive properties, such as the ability to protect neuronal cells from otherwise lethal treatments or the ability to promote the growth or regeneration of neuronal cells. In part, the inventio... | 01/13/2004 |
| 6599530 | Oral compacted composition comprising catechol derivatives The present invention relates to an oral compacted composition comprising entacapone, nitecapone, or a pharmaceutically acceptable salt thereof and croscarmellose sodium. The composition is premised on the discovery that croscarmellose sodium increases th... | 07/29/2003 |
| 6579903 | Klainetins and their derivatives, method for their preparation and use thereof The invention relates to compounds of formula I ##STR1## and of formula II ##STR2## in which R1, R2, R3, R4, R5, X1, X2, X3, X4, X5 and Y are def... | 06/17/2003 |
| 6498195 | Use of 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4'-hydroxyphenyl) as an anticarcinogenic agent Compositions and methods are provided for prevention and treatment of cancer. The compositions comprise pure hydroxylated chalcone compounds of licorice root (Glycyrrhiza glabra) including 1-propanone-1-(2,4-dihydroxyphenyl)-3-hydroxy-3-(4'-hydroxyphenyl)... | 12/24/2002 |
| 6423740 | Chalcones having antiproliferative activity The invention relates to a novel class of compounds that have structures related to certain naturally occurring or synthetic chalcones. The invention also relates to pharmaceutical compositions comprising the compounds and methods for treating certain dis... | 07/23/2002 |
| 6417233 | Ubiguinone-containing composition suitable for promoting enhanced intramitochondrial transportation of ubiguinones and methods of using same Compositions containing as active ingredients a lipid-soluble benzoquinone, e.g. Coenzyme Q10 and at least one omega-3 polyunsaturated fatty acid selected from eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and linolenic acid (LNA), for the preve... | 07/09/2002 |
| 6410602 | Method of increasing the production and improving the quality of semen A method of increasing the volume, the total sperm count and the reproductive performance of semen from human and animal males, is described. The method comprises administration of an effective dosage of a human or veterinary preparation containing at lea... | 06/25/2002 |
| 6410265 | Gene encoding a putive efflux protein for solvents/antibiotics in Pseudomonas mendocina This invention relates to the isolation of a novel putative efflux gene from Pseudomonas mendocina. The putative efflux gene is useful for probing an organism's efflux system to gain an understanding of the mechanisms of solvent tolerance. The invention f... | 06/25/2002 |
| 6335361 | Method of treating benign forgetfulness Disclosed herein are methods to treat cognition disorders, particularly those associated with aging. The method comprises administering a combination of a carnitine and an oxidant. Preferably the oxidant is thioctic acid. Preferably 0.12 grams to 3 grams ... | 01/01/2002 |
| 6306913 | Container for 4-allylanisole and analog scolytid pesticides A projectile can be used to administer pesticides such as one or more from the group consisting of 4-allylanisole, anisole, allylbenzene, 4-isopropylanisole, p-anisaldehyde, ethylbenzene, cumene, 4-methoxyacetophenone, 4-methylstyrene, 2-propylphenol, phe... | 10/23/2001 |
| 6133322 | Quinone derivatives for treating or preventing diseases associated with iron overload A method of treating or preventing a disorder resulting from a mitochondr dysfunction induced by an iron overload including Friedreich Ataxia, hypertrophic cardiomyopathy, Hallervorden-Spatz disease, sideroblastic anemia by administering an effective amo... | 10/17/2000 |
| 6107276 | Pharmaceutical compositions including a drug, a cross-linked polymeric substance, an oil, and a surface active agent The pharmaceutical compositions including a slightly soluble drug incorporated in a water-swellable, but water-insoluble cross-linked polymer, a surface active agent, and an oil show much improved dissolution and, consequently, bioavailability in respect ... | 08/22/2000 |
| 6090851 | Use of an NADPH-oxidase inhibitor in the treatment of reperfusion injury The present invention is directed to a method for the prophylactic and therapeutic treatment of reperfusion injury or injury due to a distal reperfusion. The method involves the administration of an NADPH-oxidase inhibitor to a cell, tissue, organ or anim... | 07/18/2000 |
| 6028115 | Method for preventing sexually transmitted diseases A method for the reduction in the risk of transmitting a sexually transmitted disease--especially HIV and/or HSV--during sexual activity is provided. This method generally comprises the application of an effective amount of an inhibitory agent, preferably... | 02/22/2000 |
| 5973004 | L-carnitine, acetyl-L-carnitine, and pantothenic acid or ubiquinone, combined for prevention and treatment of syndromes related to ineffective energy metabolism A combination can be of L-carnitine and acetyl-L-carnitine, preferably with pantothenic acid or ubiquinone, is administered orally or as a parenteral injection in domesticated animals, especially pet animals, and humans for prevention or treatment of synd... | 10/26/1999 |
| 5902831 | Prevention of atherosclerosis using NADPH oxidase inhibitors A method for the prevention and treatment of atherosclerosis and its related diseases in mammals, in which an NADPH oxidase inhibitor is administered, is provided. The NADPH oxidase inhibitor prevents the production of reactive oxygen species upon exposur... | 05/11/1999 |
| 5763496 | Prevention of atherosclerosis using NADPH oxidase inhibitors A method for the prevention and treatment of atherosclerosis and its related diseases in mammals is provided, in which an NADPH oxidase inhibitor is administered to mammals. The NADPH oxidase inhibitor prevents the production of reactive oxygen species up... | 06/09/1998 |
| 5654330 | Synergistic antimicrobial compositions containing a halogenated acetophenone and an organic acid Compositions for controlling the growth of microorganisms in or on a product, material or medium comprising synergistically effective amounts of halogenated acetophenones, such as 2-bromo-4-hydroxyacetophenone, and at least one organic acid, its salt or e... | 08/05/1997 |
| 5654331 | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics Diaromatic compounds, characterised in that they correspond to the following general formula: ##STR1## in which: R1 is --CH3, --CH2 OH, --COR8 or --CH2 OCOR9, R8 is H, OH, -... | 08/05/1997 |
| 5637600 | Phenylpyrrole derivatives and their use as dopamine D3 antagonists The present invention relates to pyrrole compounds, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, in particular as anti-psychotic agents.... | 06/10/1997 |
| 5527826 | Synergistic antimicrobial compositions containing a halogenated acetophenone and an organic acid Compositions for controlling the growth of microorganisms in or on a product, material or medium comprising synergistically effective amounts of halogenated acetophenones, such as 2-bromo-4-hydroxyacetophenone, and at least one organic acid, its salt or e... | 06/18/1996 |
| 5489614 | Catechol derivatives, their physiologically acceptable salts, esters and use Known and new catechol derivates may be used as medicinal antioxidants in the prevention or treatment of tissue damage induced by lipid peroxidation. The conditions and diseases to be treated are for example heart disease, rheumatoid arthritis, cancer, in... | 02/06/1996 |
| 5476876 | Di-tert-butylphenol compounds useful as anti-inflammatory agents The subject invention relates to compounds having the structure: ##STR1## wherein (a) X is selected from hydroxy, C1 to about C2 alkanoxy, thiol, C1 to about C2 alkanylthiol, and halo; (b) R and R' are each inde... | 12/19/1995 |
