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| Number | Title | Issue Date |
| 7767719 | Anthracenedione compounds This invention relates compositions containing compounds of formula (I) below: Each of R1, R2, R3, R4, R5, R6, R7, and R8 is defined in t... | 08/03/2010 |
| 7732493 | 2-substituted D-homo-estra-1,3,5(10)-trienes as inhibitors of 17β-hydroxy steroid dehydrogenase type 1 The invention relates to new 2-substituted D-homo-estra-1,3,5(10)-trienes of general formula I in which R2 means a C1-C8-alkyl group, a C1-C | 06/08/2010 |
| 7435757 | 2-substituted D-homo-estra-1,3,5(10)-trienes as inhibitors of 17β-hydroxy steroid dehydrogenase type 1 The invention relates to new 2-substituted D-homo-estra-1,3,5(10)-trienes of general formula I in which R2 means a C1-C8-alkyl group, a C1-C | 10/14/2008 |
| 7432284 | Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v... | 10/07/2008 |
| 7432303 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present inventi... | 10/07/2008 |
| 7265248 | Compositions and methods for the treatment of malaria A colchicine derivative and a method of using a colchicine derivative as a pharmacological agent in the treatment of malaria are provided. ... | 09/04/2007 |
| 7238377 | Use of an oil of the gourd family for inhibiting 5 alpha-reductase activity The invention concerns the use of at least an oil derived from the seeds of the gourd family selected from the group consisting of Lagenaria, Luffa and Momordica, for preparing a composition designed to inhibit 5α-reductase activity, and the use of sa... | 07/03/2007 |
| 7235392 | Apoptotic EBV-transformed lymphocytes, a therapeutic agent for post-transplant lymphoproliferative disorder Cell preparations comprising a plurality of apoptotic EBV-transformed B lymphocytes and methods of producing cell preparations comprising a plurality of apoptotic EBV-transformed B lymphocytes. The methods comprise transforming B lymphocytes with EBV, incubating the... | 06/26/2007 |
| 7230139 | Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid... | 06/12/2007 |
| 7217844 | Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents The present invention relates to Diterpenoid Compounds, compositions comprising an effective amount of a Diterpenoid Compound, and methods useful for treating or preventing cancer or a neoplastic disorder comprising administering an effective amount of a Diterpenoid... | 05/15/2007 |
| 7199159 | Use of biguanide derivatives for making a medicine having a wound healing effect The present invention relates to the use of biguanide derivatives of general formula I below: in which: the groups R1 and R2 represent, independently of each other, a hydrogen a... | 04/03/2007 |
| 7157477 | Aliphatic amino-substituted demethoxylated hypocrellins and their synthesis The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these compositions are disclosed. The present ... | 01/02/2007 |
| 7151196 | Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v... | 12/19/2006 |
| 7135502 | Colchinol derivatives as vascular damaging agents The invention relates to the use of compounds of formula (I): wherein X is —C(O)—, —C(S)—, —C═NOH, or —CH(R7)— wherein R7 is hydrogen, hydroxy, C1-7alkoxy, —OR8 or —NR8R9 (wherein ... | 11/14/2006 |
| 7122518 | Method for preventing or reducing collateral phototoxic damage to neighboring tissues during photodynamic therapy of a target tissue A method is provided for preventing or reducing the adverse effects of photodynamic therapy such as collateral damage by regulating the localized phototoxicity of an effector photosensitizer molecule. During photodynamic therapy, the activity of the effector photose... | 10/17/2006 |
| 7101917 | Mitochrondrial permeability transition pore affinity labels and modulators Methods of utilizing compounds of general formulas I and II as modulators and affinity labels of the MPTP complex are elucidated. Furthermore, methods for modulating the activity of the MPTP complex, methods for determining the presence of a component of the MPTP co... | 09/05/2006 |
| 7087599 | Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v... | 08/08/2006 |
| RE39199 | Antipsoriatic compositions, method of making, and method of using A psoriasis treatment composition derived from the plant Asphodelus Microcarpus includes 3-methylanthralin, chrysophanol, aloe-emodin, aloe-emodin monoacetate, and/or derivatives thereof. The composition is prepared by extracting a liquid from the Asphodelus Microca... | 07/18/2006 |
| 7060686 | Anti-inflammatory compounds derived from Methods for treating, preventing, or inhibiting diseases and disorders associated with inflammation, cell-proliferation, and pain comprising the administration of a compound having the structural formula wherein ... | 06/13/2006 |
| 7001877 | Organic laundry detergent and method of producing the same The present invention is a laundry detergent or powder and method of making the same utilizing natural components such as but not limited to milk, beeswax, sodium hydroxide or lye, vegetable or soy oil, sugar, baking soda, and corn starch. It is still further contem... | 02/21/2006 |
| 6958159 | Pharmaceutical gel composition The present invention relates to an improved pharmaceutical composition useful for the topical treatment of burns, cuts, wounds, abrasions and the like, and to methods of treatment of injured body surfaces such as skin. ... | 10/25/2005 |
| 6949250 | Selective algaecides for control of cyanochloronta We have now discovered that certain 9,10-anthraquinone derivatives we developed possess potent activity against O. perornata while possessing a sufficiently high level of solubility in water to make their activity against O. perornata viable. These com... | 09/27/2005 |
| 6949557 | Hydroanthracene based compounds as anticancer agents The invention relates to the use of novel anthracene based compounds for the inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such compounds. The invention relates more specifically to the use of hy... | 09/27/2005 |
| 6936571 | Fungicidal composition containing PQDs The present invention provides an agricultural fungicidal composition containing active compounds selected from perylenequinonoid derivatives or salts thereof. The invention also relates the application of the composition against fungal plant infections. ... | 08/30/2005 |
| 6906059 | Pharmaceutical composition with protective action against oxidative/toxic substances, especially cardiotoxic substances The use of benzazepin-N-acetic acid derivatives which contain an oxo group in the a position to the nitrogen atom and are substituted in the 3 position by a 1-(carboxyalkyl)-cyclopentyl-carbonyl-amino radical, and of their salts and biolabile esters, for the prophyl... | 06/14/2005 |
| 6903238 | Substituted indenones as estrogenic agents This invention provides estrogen receptor modulators of formula I, having the structure R1, R2, and R3 are as defined in the specification, or a pharmaceutically acceptable salt thereof... | 06/07/2005 |
| 6894073 | Use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer The disclosure concerns novel use of diterpene compound as a therapeutic agent of inlfammation, immune disease or cancer. More particularly, the present invention relates to novel use of diterpene compound that include kamebanin, kamebacetal A, kamebakaurin, and exi... | 05/17/2005 |
| 6867235 | Helianthrone derivatives as anti-cancer agents Hypericin, helianthrone and derivatives thereof of general formula (I) wherein the dotted line between positions 11 and 12 represent an optional C11-C12 bond; R is independently selected from the group consisting of hy... | 03/15/2005 |
| 6812255 | Use of aloe-emodin in the treatment of neuroectodermal tumors The invention relates to the use of anti-cancer drug of a natural compound of vegetal origin, known as aloe-emodin (AE). Indeed, said compound has proved to have a specific biological activity of inhibition on the growth of neuroectodermal tumors, without evident to... | 11/02/2004 |
| 6790463 | Uses of targeted oxidative therapeutic formulation in arteriosclerosis The use of a pharmaceutical formulation in treating coronary arteriosclerosis and a two-component pharmaceutical formulation. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by a... | 09/14/2004 |
| 6777447 | Derivatives of benzylidene cyclohexanone, benzylidene cyclopentanone, and benzylidene acetone, and therapeutic uses thereof Benzylidene cyclohexanone, cyclopentanone and acteone derivatives and therapeutic methods of using same are disclosed. The compounds are non-toxic and exhibit potent anti-inflammatory, antibacterial and antioxidation activity. Also, certain compounds of the inventio... | 08/17/2004 |
| 6773727 | Use of gossypol and related terpenes for control of urban and agricultural pests Low concentrations of gossypol and related phyllophage toxins from cotton improve the effectiveness of insecticidal agents against social insects, including cockroaches, and particularly termites and ants. Levels of gossypol and other cotton phyllophage toxins which... | 08/10/2004 |
| 6706767 | Therapeutics for chemokine mediated diseases The invention provides therapeutic and biological uses of chemokine-receptor-binding compounds including uses in the treatment of disease states mediated by chemokines. The relevant chemokines may for example be monocyte chemoattractant protein-one (MCP-1) or interl... | 03/16/2004 |
| 6696484 | Method and compositions for regulation of 5-alpha reductase activity Pharmaceutical compositions and methods for treating androgen related disorders. The pharmaceutical compositions may include a 5-reductase inhibitor, such as natural and synthetic flavanoids, catechols, curcumin-related substances, quinones, catech... | 02/24/2004 |
| 6686393 | Pharmaceutical compositions having antiviral activity against human cytomegalovirus The present invention is directed to the use of antiviral compounds having the following generalized structure: ##STR1## wherein R is 2H or .dbd.O; R' is OH, H, or COOH (single substitution); and R" is OH, H, or alkyl; and pharmaceutically acceptable salt... | 02/03/2004 |
| 6627664 | Perylenequinones for use as sonosensitizers The invention is perylenequinones that are both sonosensitizers and photosensitizers, and their therapeutic use.... | 09/30/2003 |
| 6596774 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives The present invention is the synthesis of a series of 1,5-dichloro-9(10H)-anthracenones bearing O-linked and N-linked substituents in the 10-position. These compounds were evaluated for their ability to inhibit the growth of the human oral epidermoid carc... | 07/22/2003 |
| 6586419 | Phototherapeutic inactivation of ocular viruses A method for inactivating ocular viral pathogens and for treating associated lesions on tissue by means of selectively activating a tissue-associated photosensitizing agent with light. The photosensitizing agent, preferably tin ethyl etiopurpurin, is admi... | 07/01/2003 |
| 6576674 | Method of controlling zoological and aquatic plant growth A method of controlling target aquatic microorganism pest populations by exposing the target population to a toxic amount of an aquacidal compound comprising an anthraquinone. The method is particularly effective for treating ballast water of ships or oth... | 06/10/2003 |
| 6576660 | Methods and compositions for regulation of 5--reductase activity Compounds that inhibit 5-alpha-reductase are provided. The compounds are used to treat prostate cancer, breast cancer, obesity, skin disorders and baldness.... | 06/10/2003 |
