Did You Know...
...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 6984389 | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M ... | 01/10/2006 |
| 6777447 | Derivatives of benzylidene cyclohexanone, benzylidene cyclopentanone, and benzylidene acetone, and therapeutic uses thereof Benzylidene cyclohexanone, cyclopentanone and acteone derivatives and therapeutic methods of using same are disclosed. The compounds are non-toxic and exhibit potent anti-inflammatory, antibacterial and antioxidation activity. Also, certain compounds of the inventio... | 08/17/2004 |
| 6559185 | Nitromethyl ketone compounds having aldose reduction inhibiting properties and methods for their use The present invention relates to the compounds of formula: ##STR1## in which R1, R2, R3, E, A, X, Z, p and n are as defined herein. These compounds are aldose reductase inhibitors.... | 05/06/2003 |
| 6500416 | Pesticide There are described a flowable composition for controlling harmful insects and representatives of the order Acarina, comprising at least one pesticidally active compound, one or more signal substances selected from the group consisting of pheromones, kair... | 12/31/2002 |
| 6433021 | Indane compounds and their pharmaceutical use Indane compounds of general formulae (1) to (4) and their pharmaceutical use, particularly to achieve mast cell stabilising activity and/or anti-inflammatory activity are described. In these formulae R1 to R7 may be selected from: H,... | 08/13/2002 |
| 6117887 | Inhibition of 26S and 20S proteasome by indanones This invention is novel indanone compositions useful for inhibiting cell proliferation disorders in mammals.... | 09/12/2000 |
| 6043281 | Nitromethyl ketones, process for preparing them and compositions containing them The present invention relates to the compounds of formula: ##STR1## in which R1, R2, R3, E, A, X, Z, p and n are as defined herein. These compounds are aldose reductase inhibitors.... | 03/28/2000 |
| 5834487 | Inhibition of 26S and 20S proteasome by indanones This invention is a method for inhibiting cell proliferation using indanones.... | 11/10/1998 |
| 5491140 | Naphthyl tachykinin receptor antagonists to treat physiological conditions This invention provides methods of treating a physiological disorder associated with an excess of tachykinins in a mammal which comprises administering to a mammal in need of said treatment a compound selected from a series of substituted dihydronaphthale... | 02/13/1996 |
| 5476860 | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics Diaromatic compounds, characterized in that they correspond to the following general formula: ##STR1## in which: R1 is --CH3, --CH2 OH, --COR8 or --CH2 OCOR9, R8 is H, OH, -... | 12/19/1995 |
| 5140037 | Treatment of central nervous system disorders with imidazole angiotensin-II receptor antagonists Substituted imidazoles such as 2-butyl-4-chloro-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-5-(hydroxy methyl)imidazole and 2-butyl-4-chloro-1-[(2'-carboxybiphenyl-4-yl)-methyl]-5-(hydroxymethyl)imi dazole and pharmaceutically acceptable salts there... | 08/18/1992 |
| 5106407 | Iodones and methods for antimicrobial use The present invention discloses the antimicrobial utility of certain iodonium ylide compounds. The particular iodonium ylide compounds are phenyl iodonium ylides having an ortho substituent that stabilizes the positive charge on the polyvalent iodine by a... | 04/21/1992 |
| 4791123 | Insecticidal triffluormethyl alkane derivatives There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1## in which R1, R2, R3, R4 and A have the meanings given in the description, processes for their preparation and ins... | 12/13/1988 |
| 4751240 | Phenol derivatives A phenol derivative of the formula wherein NU is a defined phenolic nucleus including a phenyl-hydroxynaphthyl; hydroxyphenyl-naphthyl; phenyl-hydroxyindanyl, phenyl-hydroxybenzothienyl or mono-hydroxyphenyl-ethylene or vinylene nucleus; wherein A is alky... | 06/14/1988 |
| 4678775 | Method of controlling pests A method of controlling a pest which comprises bringing into contact with the pest a pest-controlling amount of an agent selected from the group consisting of (1) a non-formamidine -p-octopamine agonist having substantial activity toward an octopamine rec... | 07/07/1987 |
| 4569945 | Diarylindane-1,3-diones, their preparation and use The invention is dealing with arylindane-1,3-diones of the formula: ##STR1## which can be used in the treatment of inflammatories, psoriasis and asthma.... | 02/11/1986 |
| 4393079 | Pharmaceutical compositions Anti-inflammatory compositions are prepared which comprise a therapeutically effective amount of a compound of the formula ##STR1## wherein X is CO or CHOH; Y is CO; the dotted line represents a double bond which is present or absent; R1 i... | 07/12/1983 |
| 4291061 | 1H-inden-1-one derivatives, processes for producing them, their use in microbicidal compositions, and for combating microorganisms 2,3-Dichloro-7-hydroxy-1H-inden-1-one derivatives of the formula I ##STR1## wherein R1 is hydrogen or one of the groups ##STR2## R2 and R3 independently of one another are each hydrogen, fluorine, chlorine, bromi... | 09/22/1981 |
| 4229478 | Naphthaquinone anti-psoriatic agents Psoriasis in mammals is relieved by topically administering substituted naphthaquinones of the formula: ##STR1## where R1 and R2 are the same or different and are hydrogen, hydroxy, alkoxy or acylamino and R3 is hydro... | 10/21/1980 |
| 4200577 | Coumarin derivatives Bicyclic compounds useful in the prophylaxis and treatment of allergic diseases, pharmaceutical compositions containing the same, methods of administration of the compositions, intermediates useful in preparing the compounds and conversion of the intermed... | 04/29/1980 |
| 4017639 | 2-Hydroxy-3-nitro-1,4-naphthoquinones for the prophylaxis of certain allergies Substituted naphthoquinones of the formula (I) and pharmaceutically acceptable salts thereof wherein R1, R2, R3 and R4 represent alkyl, aryl, alkoxy, hydroxy, hydrogen or halogen or any two of the groups R1... | 04/12/1977 |
| 4005219 | Pharmaceutical compositions and their administration for the prophylaxis of asthma, hayfever and rhinitis Nitro-indane-diones, their production, and pharmaceutical compositions and their administration in forms suitable for the prophylaxis of asthma, hayfever and rhinitis in amounts effective for oral, parenteral and insufflation administration for such forms... | 01/25/1977 |
| 3988476 | Pharmaceutical compositions and methods of treating allergic conditions utilizing 2-nitroindane-1,3-dione derivatives as the active agent Compositions containing 2-nitroindane-1,3-dione derivatives as active agents are useful in the prophylaxis and treatment of asthma, hay fever and also in the treatment of rhinitis.... | 10/26/1976 |
| 3978231 | Pharmaceutical compositions and method of treating allergic conditions utilizing 2-nitroindane-1,3-dione derivatives as the active agents Compositions containing 2-nitroindane-1,3-dione derivatives as active agents are useful in the prophylaxis and treatment of asthma, hayfever and also in the treatment of rhinitis.... | 08/31/1976 |
