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Class 514/649 - Amino nitrogen attached to aryl ring or aryl ring system by an acyclic carbon or acyclic chain


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein an amino nitrogen is indirectly bonded
No. of patents: 540
Last issue date: 07/05/2011


1                      
NumberTitleIssue Date
7973082Substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors
This invention relates to novel substituted aryloxy alkylamines useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprisi...
07/05/2011
7884136Modified-release formulations of a bupropion salt
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a m...
02/08/2011
7838563Compounds, formulations, and methods for ameliorating telangiectasias
Methods, compounds, and topical formulations for treatment of telangiectasias are disclosed. The methods comprise topically applying a composition comprising an α-adrenergic receptor agonist to telangiectatic skin. Amelioration of telangiectasia symptoms begins wit...
11/23/2010
7763660Inhibitors of
The invention provides methods for identifying modulators of yeast phenotypic transitions and methods for treating fungal infections with modulators of phenotypic transitions of yeast cells. These methods include methods for identifying inhibitors of the budded-to-h...
07/27/2010
7754771Compounds for the treatment of AIDS and other viral diseases
The present invention provides methods for treating Acquired Immunodeficiency Syndrome (AIDS) and other viral diseases and Human Immunodeficiency Virus (HIV) related infections by administering one or more compounds of formula I:
07/13/2010
7705054Method of preventing and/or treating oxidant injury in neurodegenerative and oxidative diseases
A method of treating and/or preventing oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or pyridoxamine or pyridoxamine analog, including embodiments where the phenolic compound ...
04/27/2010
7700657Vitamin D analogs
Novel vitamin D analogs, markedly active in the fields of cell proliferation and differentiation, are selected from among (4E,6E)-7-{3-[2-(3,4-bis-hydroxymethylphenyl)-ethyl]phenyl}-3-ethylnona-4,6-dien-3-ol, (E)-6-[3-(3,4-bis-hydroxymethylbenzyloxy)phenyl]1,1,1-tri...
04/20/2010
7671094Bupropion hydrobromide and therapeutic applications
Bupropion hydrobromide formulations as well as their use for the treatment of conditions is described. ...
03/02/2010
7655701Cycloalkylidene-(ortho substituted phenyl)-acetonitriles and their use as odorants
Compounds of formula (I) and their use as fragrance ingredients wherein R is selected from methyl, ethyl, propyl, isopropyl, methoxy and ethoxy; R is hydrogen or methyl; and n is 0 or ...
02/02/2010
7645802Bupropion hydrobromide and therapeutic applications
Bupropion hydrobromide formulations as well as their use for the treatment of conditions is described. ...
01/12/2010
7585897Modified release formulations of a bupropion salt
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a m...
09/08/2009
7569610Modified release formulations of a bupropion salt
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a m...
08/04/2009
7569611Modified release formulations of a bupropion salt
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a m...
08/04/2009
7563823Modified release formulations of a bupropion salt
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a m...
07/21/2009
7541384Mesalamine suppository
The present invention relates to a mesalamine rectal suppository designed to provide improved comfort of use. One embodiment of the invention is a mesalamine rectal suppository containing mesalamine and one or more pharmaceutically acceptable excipients, wherein the...
06/02/2009
7528175Method of treating airway diseases with beta-adrenergic inverse agonists
The use of β-adrenergic inverse agonists provides a new and highly efficient way of treating a number of pulmonary airway diseases, including asthma, emphysema, and chronic obstructive pulmonary diseases. In general, such a method involves administering a therapeut...
05/05/2009
7488759Malic acid addition salts of terbinafine
The invention concerns salts of the compound of formula I with malic acid, their preparation, corresponding pharmaceutical compositions and their use as antimycotics. ...
02/10/2009
7439241Compounds, formulations, and methods for treating or preventing rosacea
In methods, compounds, and topical formulations for treatment of rosacea incorporating compounds represented by the formulas below: wherein each of R1, R2, and R3 is independently hydrogen, ...
10/21/2008
7431916Administration of medicinal dry powders
A method of administering a metered dry powder combined dose of finely divided dry medication powders is disclosed, wherein said method comprises providing a relative motion between a nozzle of a dry powder inhaler and a dose bed carrying said combined dose of finel...
10/07/2008
7427639β2-adrenergic receptor agonists
Disclosed are multibinding compounds which are β2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor....
09/23/2008
7427414Modified release oral dosage form using co-polymer of polyvinyl acetate
Once a day modified release oral dosage form comprising of granules or pellets which are either compressed into tablet or filled inside the capsule, wherein the pellet has a core of active ingredient coated on non pareil seeds with a rate controlling functional coat...
09/23/2008
7402698Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use
The present invention is directed to secondary amino- and cycloamino-cycloalkanol derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia,...
07/22/2008
7399776Polyamine compounds for treating chemokine receptor mediated diseases
This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of the f...
07/15/2008
7384983Inhibitor of monoamine uptake
The present invention provides compounds and methods for the inhibition of monoamine uptake in mammals. ...
06/10/2008
7378552Monoamine re-uptake inhibitors and methods relating thereto
Monoamine re-uptake inhibitors and more specifically serotonin and noradrenaline re-uptake inhibitors are disclosed that have utility in the treatment of disorders of the central or peripheral nervous system in both men and women. The compounds of this invention hav...
05/27/2008
7375111Compositions for affecting weight loss
Disclosed are compositions for affecting weight loss comprising a first compound and a second compound, where the first compound is an opioid antagonist and the second compound causes increased agonism of a melanocortin 3 receptor (MC3-R) or a melanocortin 4 recepto...
05/20/2008
7368440Methods for the administration of amifostine and related compounds
The present invention provides methods of administering amifostine, WR-1065, or a combination thereof, to patients receiving radiation therapy or chemotherapy in a manner that significantly reduces or decreases the adverse or undesirable side-effects of the compound...
05/06/2008
7361686Compounds for the treatment of metabolic disorders
Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyper-lipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. Formula (I) wherein n is 1 or 2; m is 2 or 3; ...
04/22/2008
7355079Thyronamine derivatives and analogs and methods of use thereof
Thyronamine derivatives and analogs, methods of using such compounds, and pharmaceutical compositions containing them are disclosed. Methods of preparing such compounds are also disclosed. ...
04/08/2008
7342133Substituted amino compounds as 5-HT/NA uptake inhibitors
The invention relates to substituted amino compounds, to processes for their preparation, to pharmaceutical formulations containing these compounds and to the use of these substances in the preparation of pharmaceutical formulations, especially for the treatment or ...
03/11/2008
7339079Thyronamine derivatives and analogs and methods of use thereof
Thyronamine derivatives and analogs, methods of using such compounds, and pharmaceutical compositions containing them are disclosed. Methods of preparing such compounds are also disclosed. ...
03/04/2008
7334538Topical medicants for aquatic animals
A topical medicant for fishes, amphibians, reptiles, and aquatic macroinvertebrates applied in a site-specific manner for the localized treatment of skin wounds, lesions and diseases. The medicant comprises a hydrophilic carrier with an antimicrobial therapeutant fo...
02/26/2008
7332525Method of treatment of prostate cancer and composition for treatment thereof
A method and composition for the treatment of prostate cancer comprises an effective amount of a nonsteroidal antiandrogen and an effective amount of a selective estrogen receptor modulator. The composition has fewer side effects such as breast tenderness and gyneco...
02/19/2008
7326730Aminoadamantane derivatives as therapeutic agents
The present invention provides novel aminoadamantane derivatives, methods of making the derivatives, compositions including the novel aminoadamantane derivatives, and methods for the treatment and prevention of neurological diseases using the derivatives and composi...
02/05/2008
7321065Thyronamine derivatives and analogs and methods of use thereof
Thyronamine derivatives and analogs, methods of using such compounds, and pharmaceutical compositions containing them are disclosed. Methods of preparing such compounds are also disclosed. ...
01/22/2008
7317127Process for the optical resolution and recycling of tomoxetine
The present invention provides a process for the optical resolution of racemic tomoxetine under reaction conditions that improve reaction yields and optical purity. The invention also provides an epimerization process for the (S)-(+) enantiomer. The invention furthe...
01/08/2008
7297820Stilbene derivatives and their use for binding and imaging amyloid plaques
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregat...
11/20/2007
7294649Methamphetamine derivatives and conjugates for immunoassay
Compounds of methamphetamine derivatives having a meta-substituted alkyl linker on the benzene ring and a protective group on the nitrogen of the methamphetamine hapten. Such compounds have the structure wherein ...
11/13/2007
7288571Thyroid receptor ligands and method II
New thyroid receptor ligands are provided which have general formula (I) in which: n is an integer from 0 to 4; R1 is halogen, trifluoromethyl, or alkyl of 1 to 6 carbons or cycloalkyl of 3 to 7 carbons; R2 and R3 are the same or dif...
10/30/2007
7276518Substituted cyclohexane-1,4-diamine compounds
Substituted cyclohexane-1,4-diamine compounds, methods for production thereof, pharmaceutical compositions comprising these compounds and methods of treatment using these compounds. ...
10/02/2007
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