Class 514/631 - Amidines (i.e., N=C-N)

Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter containing amidines which have the grouping
No. of patents: 118
Last issue date: 03/25/2008

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Number	Title	Issue Date
7348319	Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same The present invention relates to nitric oxide-releasing amidine diazeniundiolates, compositions comprising same, methods of using same, and a method for preparing same from imidate diazeniumdiolates and primary or secondary amines. ...	03/25/2008
7326730	Aminoadamantane derivatives as therapeutic agents The present invention provides novel aminoadamantane derivatives, methods of making the derivatives, compositions including the novel aminoadamantane derivatives, and methods for the treatment and prevention of neurological diseases using the derivatives and composi...	02/05/2008
7322369	Methods of detaching microorganisms from, or of inhibiting microbial attachment to, animal or poultry carcasses or seafood or parts thereof Methods of detaching microorganisms (e.g., bacteria) from, or of inhibiting microbial (e.g., bacterial) attachment to, animal or poultry carcasses or seafood or parts thereof, wherein the method involves contacting animal or poultry carcasses or seafood or parts the...	01/29/2008
7317040	Nitric oxide synthase inhibitor phosphate salt A compound of formula (I): namely (2S)-2-amino-4-{[2-(ethanimidoylamino)ethyl]thio}butanoic acid, compound with phosphoric acid, or a solvate or physiologically functional derivative thereof, is useful as a relat...	01/08/2008
7285573	Use of creatine or creatine analogs for the treatment of diseases of the nervous system The present invention relates to the use of creatine compounds including creatine, creatine phosphate or analogs of creatine, such as cyclocreatine, for treating diseases of the nervous system. Creatine compounds can be used as therapeutically effective agents again...	10/23/2007
7265136	Substituted stilbene compounds with vascular damaging activity A compound for use in inducing necrosis in vascular tissue of a tumor in an animal. The compound contains a first moiety which is a cis-stilbene moiety and a second moiety which is an inhibitor of the formation or action of nitric acid. Also, a method for inducing n...	09/04/2007
7169814	Guanidinium transport reagents and conjugates Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurality of guanidinium moieties that are either contiguous or spaced along a backbone, but are sufficiently removed fro...	01/30/2007
7163923	Peptide deformylase activated prodrugs This invention provides a method for inhibiting the growth of a microorganism that expresses Peptide Deformylase by contacting the microorganism with an effective amount of the compound described herein. This method inhibits the growth of gram-positive and gram-nega...	01/16/2007
7145037	Adamantane derivatives with neuroprotective, antidepressant and anti-ischaemic activities, and process for preparing them The invention describes compounds represented by the general formula (I) given below: in which: n is an integer between 1 and 4; R1 and R2	12/05/2006
7122535	Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them A method of treating pain in a warm-blooded animal comprising administering to anwarm-blooded animal in need thereof an amount of a compound of the formula wherein the substituents are defined in accordance with the di...	10/17/2006
7115665	Inhibitors of endo-exonuclease activity for treating cancer The present invention relates to the treatment of cancer with compounds that inhibit the activity of endo-exonuclease. Endo-exonuclease has been shown to be necessary for the repair of damaged DNA. Compounds that inhibit the activity of endo-exonuclease have been sh...	10/03/2006
6960574	Antagonists of RF-amide neuropeptides Disclosed are compounds having the formula: where R1=H, C1-C6 alkyl, cycloalkyl, R2...	11/01/2005
6911478	Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitric oxide-releasing amidine- a...	06/28/2005
6911477	Muscarinic receptor agonists This invention relates to a novel class of partial or full muscarinic receptor agonists intermediates for their preparation, and pharmaceutical compositions and methods of use for the treatment or prevention of diseases the treatment or prevention of which is mediat...	06/28/2005
6884784	Diagnosis and management of infection caused by chlamydia The present invention provides a unique approach for the diagnosis and management of infections by Chlamydia species, particularly C. pneumoniae. The invention is based, in part, upon the discovery that a combination of agents directed toward the vario...	04/26/2005
6849662	Therapeutic uses for nitric oxide inhibitors The present invention is based on the discovery that nitric oxide (NO) is an important growth regulator in an intact developing organism. In particular, the present invention relates to a method of increasing in a mammal a population of hematopoietic stem cells whic...	02/01/2005
6809117	Therapeutic uses of nitric oxide inhibitors The present invention is based on the discovery that nitric oxide (NO) is an important growth regulator in an intact developing organism. In particular, the present invention relates to a method of increasing in a mammal a population of hematopoietic stem cells in b...	10/26/2004
6809088	Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them The invention relates to new derivatives of 2-(iminomethyl)amino-phenyl which are NO synthase inhibitors and can trap reactive oxygen species. These compounds can notably be used for the treatment of stroke, of neurodegenerative diseases and of ischemic or hemorragi...	10/26/2004
6797707	Antagonists of RF-amide neuropeptides Disclosed are compounds having the formula: where R1=H, C1-C6 alkyl, cycloalkyl, R2=H, C1-C6 alkyl, cycloalkyl	09/28/2004
6767548	Gel inhibited liquid carrier for a biocide containing a carbodiimide and an emulsifier mixture This invention relates to a biocidal composition resistant to the formation of a gel and to the method for stabilizing a concentrate containing, in addition to the biocide, a carbodiimide, a lipophilic/hydrophilic emulsifier mixture having a HLB of 6 to 20 and optio...	07/27/2004
6750254	Nitric oxide-releasing amidine—and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same The present invention relates to nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions comprising such compounds, methods of using such compounds and compositions, and to a method for the preparation of nitric oxide-releasing amidine- a...	06/15/2004
6750211	Diimino compounds for use as modulators of cell regulation Compositions, methods of use, isolation and biosynthesis of diimino-piperazine derivatives useful for the modification of sphingolipid metabolism and other biological functions are described. The preferred derivative is 2,6-bis-(ω-aminobutyl)-3,5-diimino-piperazine...	06/15/2004
6747062	Regulation of wound healing by nitric oxide The present invention provides methods and compositions for promoting healing of damaged tissue that result in an increased level of nitric oxide in the vicinity of the damaged tissue. Also provided are methods and compositions for inhibiting unwanted wound healing ...	06/08/2004
6740653	Shelf life extension of microemulsions containing active aza biocide This invention relates to the stabilization of o/w microemulsions containing an active aza biocide by addition of an alkaline, water soluble buffering agent in an amount sufficient to adjust the pH to between 6 and 14 and to the use of said o/w microemulsions to con...	05/25/2004
6706764	Use of creatine or creatine analogs for the treatment of diseases of the nervous system The present invention relates to the use of creatine compounds including creatine, creatine phosphate or analogs of creatine, such as cyclocreatine, for treating diseases of the nervous system. Creatine compounds can be used as therapeutically effective agents again...	03/16/2004
6706754	Reversed amidines and methods of using for treating, preventing, or inhibiting leishmaniasis Methods for treating, preventing or inhibiting leishmaniasis in a subject comprising administering to the subject a therapeutically effective amount of at least one compound having the structural formula wherein Y is a h...	03/16/2004
6693125	Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders The invention features a method for treating a patient having a cancer or other neoplasm, by administering to the patient (i) a benzimidazole or a metabolite or analog thereof; and (ii) pentamidine or a metabolite or analog thereof simultaneously or withi...	02/17/2004
6641800	Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer soluble in the liquefied hydrofluoroalkane which is selected fr...	11/04/2003
6627631	Pharmaceutical composition containing desoxypeganine for the treatment of alcoholism Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of alcoholism. Said substances are administered preferably in a continuos and controlled manner. The pharmaceutical administration form enables controlled ...	09/30/2003
6620840	Derivatives of N-(iminomethyl)amines, their preparation, their use as medicaments and the pharmaceutical compositions containing them N-(imino)amines and their preparation and their use as NO synthase inhibitors and selective or non-selective traps for a reactive oxygen species....	09/16/2003
6599511	Pharmaceutical composition containing desoxypeganine for the treatment of drug dependence Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of drug addiction or drug dependence. Said substances are administered preferably in a continuos and controlled manner. The pharmaceutical administration f...	07/29/2003
6593372	Therapeutic uses for nitric oxide inhibitors The present invention is based on the discovery that nitric oxide (NO) is an important growth regulator in an intact developing organism. In particular, the present invention relates to a method of increasing in a mammal a population of hematopoietic stem...	07/15/2003
6586471	Halogenated 2-amino-3, 4 heptenoic acid derivatives useful as nitric oxide synthase inhibitors The present invention contains halogenated 2-amino-3,4 heptenoic acid derivatives useful as nitric oxide synthase inhibitors....	07/01/2003
6579854	Diagnosis and management of infection caused by chlamydia The present invention provides a unique approach for the diagnosis and management of infections by Chlamydia species, particularly C. pneumoniae. The invention is based, in part, upon the discovery that a combination of agents directed toward the various ...	06/17/2003
6545055	Inhibitors of factor Xa Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders....	04/08/2003
6534543	Oxa acids and related compounds for treating skin conditions The present invention is directed to the use of compounds of Formula (I), as active principals for treating skin conditions and compositions containing these compounds ##STR1## wherein R4 is (CR5 R6 -CR7 R8...	03/18/2003
6531506	Inhibitors of epoxide hydrolases for the treatment of hypertension The invention provides compounds that inhibit epoxide hydrolase in therapeutic applications for treating hypertension. A preferred class of compounds for practicing the invention have the structure shown by Formula I ##STR1## wherein Z is oxygen or s...	03/11/2003
6509022	Composition for use in personal care comprising organic acid salts of polymeric biguanidines Cosmetic composition for use in personal care applications comprising a carrier and a polymeric biguanide, characterised in that the polymeric biguanide is in the form of its salt with an organic acid containing from 4 to 30 carbon atoms....	01/21/2003
6500866	1-(adamantyl)amidines and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmission Compounds of 1-(adamantyl) amidine and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmittion....	12/31/2002
6444706	Guanidine derivatives, processes for preparing them and their use as pharmaceutical compositions The invention concerns new guanidine derivatives of formula (I), methods of preparing them and their use in drugs containing such compounds. ##STR1##...	09/03/2002

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Class 514/631 - Amidines (i.e., N=C-N)