...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 7288538 | Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use. ... | 10/30/2007 |
| 7282224 | Pain relief composition Disclosed is a pain relief composition comprising an effective amount of a nerve inhibiting component, including capsaicin, a capsaicinoid or a capsaicin analogue, which numbs or inhibits the nerve endings that signal pain, in combination with at least one of the fo... | 10/16/2007 |
| 7235257 | Drugs for relieving hemicrania comprising 1-menthol and essential oils This invention relates to external drugs for dermal application which have a migraine-alleviating effect, in more detail ointments and patches comprising in mixing l-menthol and an essential oil into a base containing a hydrophilic high-molecular weight compound, a ... | 06/26/2007 |
| 7196119 | Development of new selective estrogen receptor modulators The present disclosure concerns a new class of selective estrogen receptor modulators (SERMs). The disclosure also includes the identification of a previously unknown membrane associated estrogen receptor. Methods for making and using the disclosed SERMs are disclos... | 03/27/2007 |
| 7169748 | Fragrance compounds Novel compounds having the structure (I) where R=methyl, ethyl or propyl, R1=methyl or H, R2=methyl, ethyl or propyl, R3=methyl or H, R4=methyl or ethyl, R5═H or methyl, and where R3 and R5 | 01/30/2007 |
| 7161016 | Cannabimimetic lipid amides as useful medications Novel analogs of arachidonylethanolamide are presented which have higher affinities for the cannabinoid CB1 and/or CB2 receptor sites. Further, most of the analogs exhibit greater metabolic stability than arachidonylethanolamide. The improved receptor affinity and s... | 01/09/2007 |
| 7097771 | In-tank time release ion exchange resin containing a fuel additive The invention provides a device containing an ion-exchange resin to which is chemically bound a fuel additive material which will gradually be released from the resin into a fuel in which the device is placed. ... | 08/29/2006 |
| 7060307 | Topical composition for heightened sensitivity The invention is directed to a topical composition for heightened sensitivity and arousal for humans. The topical composition includes an organic fluid carrier, preferably glycerin, containing an effective amount of capsaicinoids extract, the active principle in chi... | 06/13/2006 |
| 7049329 | Amines that inhibit a mammalian anandamide transporter, and methods of use thereof One aspect of the present invention relates to amines. A second aspect of the present invention relates to the use of the amines as inhibitors of a mammalian anandamide transporter. The compounds of the present invention will also find use in the treatment of numero... | 05/23/2006 |
| 7015251 | Combinations of ceramide and chemotherapeutic agents for inducing tumor cell death This invention provides a method for increasing apoptosis in tumor cells and a method of decreasing a size of a tumor, said methods comprising contacting the tumor cells with: a) an effective amount of at least one antitumor chemotherapeutic agent and b) an effectiv... | 03/21/2006 |
| 6956059 | Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use The present invention ralates to compounds of formula (I): wherein R is hydrogen (H) or C1-6 alkyl; and X is defined such that —NH—(X)—COOH is the residue of an amino acid, which amino acid may itself optionally be substituted at any pendant amino g... | 10/18/2005 |
| 6916852 | Method for regulation of microvascular tone Methods and kits for regulating arterial microvascular tone in which a COX-2 inhibitor and a cannabinoid receptor agonist are co-administered to a subject. ... | 07/12/2005 |
| 6903052 | Nematicidal compositions and methods The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes that parasitize animals can also be controlled using the methods and composition of this invention. Certain of the us... | 06/07/2005 |
| 6846940 | Ceramides, compositions thereof and methods of use thereof Novel ceramide compounds, compositions containing them and the use of these compounds, in particular for strengthening the lipid barrier of the epidermis. ... | 01/25/2005 |
| 6812254 | Pain reliever and method of use A composition containing capsaicin together with other ingredients to neutralize the discomfort resulting from the application of capsaicin to the ski enabling treatment of many types of discomforts, including arthritis pain, neuropathy, post surgical scarring, hemo... | 11/02/2004 |
| 6800770 | Anti-spasticity of an eicosanoid analog The invention compounds and methods for the treatment of motor disorders. In particular, the invention provides eicosanoid analogs which are effective in ameliorating motor disorders such as spasticity caused by multiple sclerosis (MS). ... | 10/05/2004 |
| 6747164 | Use of amine compounds with improved biodegradability as adjuvants for pesticides and fertilizers The present invention relates to the use of an amino compound, which is an esteramine or an amidoamine surfactant with improved biodegradability, as an adjuvant for agrochemically active compounds such as pesticides or fertilizers. The adjuvant has Formula (I) where... | 06/08/2004 |
| 6734204 | Serotonin potentiation by oleamide analogs Analogs related to oleamide are employed for potentiating the 5-HT2A and 5-HT1A responses to serotonin (5-HT). With respect to the potentiation of the 5-HT2A receptor response, it is disclosed that, of the naturally occurring fatty a... | 05/11/2004 |
| 6699851 | Cytotoxic compounds and their use Novel amides of polyunsaturated fatty acids with cysteamine-S-phosphate have been synthesized. Combinations of the all-trans-retinoic acid and/or amides of the 13-cis-retinoic acid with O-phospho-L-tyrosine, and N-docosahexaenoyl-cysteamine-S-phosphate, ... | 03/02/2004 |
| 6689399 | Transdermal delivery of an anti-inflammatory composition The present invention provides an anti-inflammatory composition for treatment of joint and muscle pain through transdermnal delivery of a capsacinoid in conjunction with glucosamine. The ingredients of the composition of the present invention, namely, a c... | 02/10/2004 |
| 6685953 | External preparation compositions The present invention relates to a dermatologic preparation containing a diamide derivative represented by the following formula (1): ##STR1## (wherein, R1 represents a linear or branched hydrocarbon group having 1 to 22 carbon atoms which may ... | 02/03/2004 |
| 6656972 | Control of pain with endogenous cannabinoids Novel pharmaceutical therapeutic compositions and methods for using same for the treatment of pain experienced by an individual are provided. The compositions contain at least one member selected from among anandamide and palmitylethanolamide.... | 12/02/2003 |
| 6653352 | Pain reliever and method of use A composition containing capsicium extract together with other ingredients to neutralize the discomfort resulting from the application of capsicium extract to the skin enabling treatment of many types of discomforts, including arthritis pain, neuropathy, ... | 11/25/2003 |
| 6632839 | Capsicum based disinfectant and sterilizant A method and formulation for sterilizing and disinfecting surfaces, and for killing bacteria on contact, the sterilizing and disinfecting formulation containing water and between about 0.0001 percent and about 10.0 percent by weight capsicum, the method a... | 10/14/2003 |
| 6605641 | 20-HETE antagonists and agonists 20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of 21-hydroxyheneicosa-5(Z), 8(Z), 11(Z), 14(Z)-tetraenoic acid, 20-hydr... | 08/12/2003 |
| 6599941 | Insecticide and insect repellant compositions A non-toxic, environmentally safe and easily employable insecticide and insect repellent is achieved by providing an aqueous composition incorporating ethanolamine based compounds, either independently or in combination with the ethanolamine based compoun... | 07/29/2003 |
| 6596769 | 20-Hete antagonists and agonists 20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of 21-hydroxyheneicosa-5(Z),8(Z),11(Z),14(Z)-tetraenoic acid, 20-hy... | 07/22/2003 |
| 6593371 | Treatment for wart and related disorders A novel treatment for wart and related disorders such as papillomas derived from extracts of pepper, ginger, and related plant species containing vanillyl (FIG. 3), and piperidine (FIG. 7) ring structures typical of the pungent principals found in pepper,... | 07/15/2003 |
| 6593370 | Topical capsaicin preparation A topical capsaicin preparation for the treatment of painful cutaneous disorders and neural dysfunction is disclosed. The preparation contains a nonionic, amphoteric or cationic surfactant in an amount effective to eliminate or substantially ameliorate bu... | 07/15/2003 |
| 6593366 | Ionic polymers as anti-infective agents A method for treating a microbial infection in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising an amino group or an ammonium group attached to the polymer backbone via an aliphatic ... | 07/15/2003 |
| 6589992 | Inhibiting collagen-induced platelet aggregation The present invention describes a therapeutic method useful for treating or preventing a condition of platelet aggregation in a subject including administering to the subject a pharmaceutically effective amount of a compound or composition that inhibits B... | 07/08/2003 |
| 6573302 | Cream utilizing capsaicin A cream comprising: a topical carrier wherein the topical carrier comprises a member selected from the group comprising lavender oil, myristal myristate, and other preservatives including, hypericum perforatum arnica montana capric acid; and 0.01 to 1.0 w... | 06/03/2003 |
| 6489291 | Topical composition for skin A topical skin composition containing a dipeptide compound represented by, formula (1) or a salt of the dipeptide: ##STR1## wherein R1 represents a, hydrogen atom, an alkyl group, an alkanoyl group, or --CH(R6)COOR7 (where... | 12/03/2002 |
| 6436996 | Modulation of nitric oxide production A method of treating cells that carry at least one APOE4 allele comprises increasing nitric oxide levels in the cells (e.g., by administering an exogenous source of nitric oxide to the cells) by an amount sufficient to combat the decrease of nitric oxide ... | 08/20/2002 |
| 6410597 | Hydroxyalkyl amide analogs of ceramide The present invention provides methods for treating disease conditions associated with abnormal cellular proliferation, inflammation and viral infection or proliferation by the administration of ceramic analogs. The ceramic analogs appear to be specific f... | 06/25/2002 |
| 6399073 | Capsicum lachrymator The present invention provides a capsicum containing lachrymator. The lachrymator comprises a nonflammable carrier and capsicum. The nonflammable carrier comprises propylene glycol, ethyl alcohol and water. In one preferred embodiment the lachrymator comp... | 06/04/2002 |
| 6395777 | Ionic polymers as anti-infective agents A method for treating a microbial infection in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising an amino group or an ammonium group attached to the polymer backbone via an aliphatic ... | 05/28/2002 |
| 6395781 | 20-HETE antagonists and agonists 20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of 21-hydroxyheneicosa-5(Z),8(Z),11(Z),14(Z)-tetraenoic acid, 20-hy... | 05/28/2002 |
| 6391909 | Anandamide inhibitors as analgesic agents Disclosed is a method of inhibiting anandamide amidase in an individual or animal and novel inhibitors of anandamide amidase. The disclosed method can be used to reduce pain in an individual or animal suffering from pain, reducing nausea in an individual ... | 05/21/2002 |
| 6359010 | Methods of treating anxiety and mood disorders with oleamide A method of treating conditions characterized by anxiety and/or depression, by the administration of oleamide or related compounds is disclosed.... | 03/19/2002 |