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...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.

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Class 514/627 - Carbon to carbon unsaturation in R


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the carboxylic acid residue (R) contains
No. of patents: 239
Last issue date: 10/30/2007


1            
NumberTitleIssue Date
7288538Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists
The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use. ...
10/30/2007
7282224Pain relief composition
Disclosed is a pain relief composition comprising an effective amount of a nerve inhibiting component, including capsaicin, a capsaicinoid or a capsaicin analogue, which numbs or inhibits the nerve endings that signal pain, in combination with at least one of the fo...
10/16/2007
7235257Drugs for relieving hemicrania comprising 1-menthol and essential oils
This invention relates to external drugs for dermal application which have a migraine-alleviating effect, in more detail ointments and patches comprising in mixing l-menthol and an essential oil into a base containing a hydrophilic high-molecular weight compound, a ...
06/26/2007
7196119Development of new selective estrogen receptor modulators
The present disclosure concerns a new class of selective estrogen receptor modulators (SERMs). The disclosure also includes the identification of a previously unknown membrane associated estrogen receptor. Methods for making and using the disclosed SERMs are disclos...
03/27/2007
7169748Fragrance compounds
Novel compounds having the structure (I) where R=methyl, ethyl or propyl, R1=methyl or H, R2=methyl, ethyl or propyl, R3=methyl or H, R4=methyl or ethyl, R5═H or methyl, and where R3 and R5
01/30/2007
7161016Cannabimimetic lipid amides as useful medications
Novel analogs of arachidonylethanolamide are presented which have higher affinities for the cannabinoid CB1 and/or CB2 receptor sites. Further, most of the analogs exhibit greater metabolic stability than arachidonylethanolamide. The improved receptor affinity and s...
01/09/2007
7097771In-tank time release ion exchange resin containing a fuel additive
The invention provides a device containing an ion-exchange resin to which is chemically bound a fuel additive material which will gradually be released from the resin into a fuel in which the device is placed. ...
08/29/2006
7060307Topical composition for heightened sensitivity
The invention is directed to a topical composition for heightened sensitivity and arousal for humans. The topical composition includes an organic fluid carrier, preferably glycerin, containing an effective amount of capsaicinoids extract, the active principle in chi...
06/13/2006
7049329Amines that inhibit a mammalian anandamide transporter, and methods of use thereof
One aspect of the present invention relates to amines. A second aspect of the present invention relates to the use of the amines as inhibitors of a mammalian anandamide transporter. The compounds of the present invention will also find use in the treatment of numero...
05/23/2006
7015251Combinations of ceramide and chemotherapeutic agents for inducing tumor cell death
This invention provides a method for increasing apoptosis in tumor cells and a method of decreasing a size of a tumor, said methods comprising contacting the tumor cells with: a) an effective amount of at least one antitumor chemotherapeutic agent and b) an effectiv...
03/21/2006
6956059Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use
The present invention ralates to compounds of formula (I): wherein R is hydrogen (H) or C1-6 alkyl; and X is defined such that —NH—(X)—COOH is the residue of an amino acid, which amino acid may itself optionally be substituted at any pendant amino g...
10/18/2005
6916852Method for regulation of microvascular tone
Methods and kits for regulating arterial microvascular tone in which a COX-2 inhibitor and a cannabinoid receptor agonist are co-administered to a subject. ...
07/12/2005
6903052Nematicidal compositions and methods
The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes that parasitize animals can also be controlled using the methods and composition of this invention. Certain of the us...
06/07/2005
6846940Ceramides, compositions thereof and methods of use thereof
Novel ceramide compounds, compositions containing them and the use of these compounds, in particular for strengthening the lipid barrier of the epidermis. ...
01/25/2005
6812254Pain reliever and method of use
A composition containing capsaicin together with other ingredients to neutralize the discomfort resulting from the application of capsaicin to the ski enabling treatment of many types of discomforts, including arthritis pain, neuropathy, post surgical scarring, hemo...
11/02/2004
6800770Anti-spasticity of an eicosanoid analog
The invention compounds and methods for the treatment of motor disorders. In particular, the invention provides eicosanoid analogs which are effective in ameliorating motor disorders such as spasticity caused by multiple sclerosis (MS). ...
10/05/2004
6747164Use of amine compounds with improved biodegradability as adjuvants for pesticides and fertilizers
The present invention relates to the use of an amino compound, which is an esteramine or an amidoamine surfactant with improved biodegradability, as an adjuvant for agrochemically active compounds such as pesticides or fertilizers. The adjuvant has Formula (I) where...
06/08/2004
6734204Serotonin potentiation by oleamide analogs
Analogs related to oleamide are employed for potentiating the 5-HT2A and 5-HT1A responses to serotonin (5-HT). With respect to the potentiation of the 5-HT2A receptor response, it is disclosed that, of the naturally occurring fatty a...
05/11/2004
6699851Cytotoxic compounds and their use
Novel amides of polyunsaturated fatty acids with cysteamine-S-phosphate have been synthesized. Combinations of the all-trans-retinoic acid and/or amides of the 13-cis-retinoic acid with O-phospho-L-tyrosine, and N-docosahexaenoyl-cysteamine-S-phosphate, ...
03/02/2004
6689399Transdermal delivery of an anti-inflammatory composition
The present invention provides an anti-inflammatory composition for treatment of joint and muscle pain through transdermnal delivery of a capsacinoid in conjunction with glucosamine. The ingredients of the composition of the present invention, namely, a c...
02/10/2004
6685953External preparation compositions
The present invention relates to a dermatologic preparation containing a diamide derivative represented by the following formula (1): ##STR1## (wherein, R1 represents a linear or branched hydrocarbon group having 1 to 22 carbon atoms which may ...
02/03/2004
6656972Control of pain with endogenous cannabinoids
Novel pharmaceutical therapeutic compositions and methods for using same for the treatment of pain experienced by an individual are provided. The compositions contain at least one member selected from among anandamide and palmitylethanolamide....
12/02/2003
6653352Pain reliever and method of use
A composition containing capsicium extract together with other ingredients to neutralize the discomfort resulting from the application of capsicium extract to the skin enabling treatment of many types of discomforts, including arthritis pain, neuropathy, ...
11/25/2003
6632839Capsicum based disinfectant and sterilizant
A method and formulation for sterilizing and disinfecting surfaces, and for killing bacteria on contact, the sterilizing and disinfecting formulation containing water and between about 0.0001 percent and about 10.0 percent by weight capsicum, the method a...
10/14/2003
660564120-HETE antagonists and agonists
20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of 21-hydroxyheneicosa-5(Z), 8(Z), 11(Z), 14(Z)-tetraenoic acid, 20-hydr...
08/12/2003
6599941Insecticide and insect repellant compositions
A non-toxic, environmentally safe and easily employable insecticide and insect repellent is achieved by providing an aqueous composition incorporating ethanolamine based compounds, either independently or in combination with the ethanolamine based compoun...
07/29/2003
659676920-Hete antagonists and agonists
20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of 21-hydroxyheneicosa-5(Z),8(Z),11(Z),14(Z)-tetraenoic acid, 20-hy...
07/22/2003
6593371Treatment for wart and related disorders
A novel treatment for wart and related disorders such as papillomas derived from extracts of pepper, ginger, and related plant species containing vanillyl (FIG. 3), and piperidine (FIG. 7) ring structures typical of the pungent principals found in pepper,...
07/15/2003
6593370Topical capsaicin preparation
A topical capsaicin preparation for the treatment of painful cutaneous disorders and neural dysfunction is disclosed. The preparation contains a nonionic, amphoteric or cationic surfactant in an amount effective to eliminate or substantially ameliorate bu...
07/15/2003
6593366Ionic polymers as anti-infective agents
A method for treating a microbial infection in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising an amino group or an ammonium group attached to the polymer backbone via an aliphatic ...
07/15/2003
6589992Inhibiting collagen-induced platelet aggregation
The present invention describes a therapeutic method useful for treating or preventing a condition of platelet aggregation in a subject including administering to the subject a pharmaceutically effective amount of a compound or composition that inhibits B...
07/08/2003
6573302Cream utilizing capsaicin
A cream comprising: a topical carrier wherein the topical carrier comprises a member selected from the group comprising lavender oil, myristal myristate, and other preservatives including, hypericum perforatum arnica montana capric acid; and 0.01 to 1.0 w...
06/03/2003
6489291Topical composition for skin
A topical skin composition containing a dipeptide compound represented by, formula (1) or a salt of the dipeptide: ##STR1## wherein R1 represents a, hydrogen atom, an alkyl group, an alkanoyl group, or --CH(R6)COOR7 (where...
12/03/2002
6436996Modulation of nitric oxide production
A method of treating cells that carry at least one APOE4 allele comprises increasing nitric oxide levels in the cells (e.g., by administering an exogenous source of nitric oxide to the cells) by an amount sufficient to combat the decrease of nitric oxide ...
08/20/2002
6410597Hydroxyalkyl amide analogs of ceramide
The present invention provides methods for treating disease conditions associated with abnormal cellular proliferation, inflammation and viral infection or proliferation by the administration of ceramic analogs. The ceramic analogs appear to be specific f...
06/25/2002
6399073Capsicum lachrymator
The present invention provides a capsicum containing lachrymator. The lachrymator comprises a nonflammable carrier and capsicum. The nonflammable carrier comprises propylene glycol, ethyl alcohol and water. In one preferred embodiment the lachrymator comp...
06/04/2002
6395777Ionic polymers as anti-infective agents
A method for treating a microbial infection in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising an amino group or an ammonium group attached to the polymer backbone via an aliphatic ...
05/28/2002
639578120-HETE antagonists and agonists
20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of 21-hydroxyheneicosa-5(Z),8(Z),11(Z),14(Z)-tetraenoic acid, 20-hy...
05/28/2002
6391909Anandamide inhibitors as analgesic agents
Disclosed is a method of inhibiting anandamide amidase in an individual or animal and novel inhibitors of anandamide amidase. The disclosed method can be used to reduce pain in an individual or animal suffering from pain, reducing nausea in an individual ...
05/21/2002
6359010Methods of treating anxiety and mood disorders with oleamide
A method of treating conditions characterized by anxiety and/or depression, by the administration of oleamide or related compounds is disclosed....
03/19/2002
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