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| Number | Title | Issue Date |
| 8106094 | Compositions and methods for treating skin conditions This invention relates to methods and compositions for treating and ameliorating skin conditions including post inflammatory hyperpigmentation (PIH). More particularly, this invention relates to compositions containing certain natural extracts, salicylic acid, and n... | 01/31/2012 |
| 8093293 | Methods for treating skin conditions This invention relates to methods and compositions for treating and ameliorating skin conditions including acne, rosacea and wrinkling caused by photodamage or intrinsic aging. More particularly, this invention relates to compositions containing certain natural extr... | 01/10/2012 |
| 8030352 | Method of producing retinyl esters A method of producing a retinyl ester compound comprising subjecting a composition comprising retinyl or a retinyl ester and a fat or oil of animal or vegetable origins to enzyme catalysed trans-esterification in solvent free conditions to produce a retinyl ester. | 10/04/2011 |
| 8026280 | Histone deacetylase inhibitors Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, such as, for example, a carboxylic acid group, can inhibit histone deacetylase. Histone deacetylase inhibition can repress gene expression, including expres... | 09/27/2011 |
| 7714024 | Compositions and methods for the intraocular transport of therapeutic agents Membrane transporter-targeted therapeutic agents and methods of making and using the same. ... | 05/11/2010 |
| RE41134 | Slow release vehicles for minimizing skin irritancy of topical compositions Staple Stable, aqueous gel vehicles are provided for the topical application to the skin of irritating active ingredients such as retinoids, particularly tretinoin, with slow release of the active ingredient and minimal irritancy to the skin. The vehicles include a... | 02/16/2010 |
| 7662855 | Retinoid solutions and formulations made therefrom Compositions for topical application for treating a skin disorder (e.g., acne) include a retinoid, which is solubilized completely in alcohol only with the aid of cosolvents such as esters (e.g., alkyl benzoate, isopropyl palmitate, isopropyl myristate, diisopropyl ... | 02/16/2010 |
| 7576131 | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia The present invention provides the use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes, hyperlipidemia and hyperuricemia. ... | 08/18/2009 |
| 7534817 | Kombic acid/sarganol bis-succinate and derivatives as potent apoptogens (antineoplastic agents) with high selectivity for cancer cells This invention provides sarganol bis-succinate and alkyl and aryl derivatives thereof as potent apoptogens (antineoplastic agents) with high selectivity for cancer cells. ... | 05/19/2009 |
| 7425649 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia. ... | 09/16/2008 |
| 7417022 | Compounds and compositions for delivering active agents Modified amino acid compounds useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 08/26/2008 |
| 7396946 | Compound for treatment of external secretion disorders Disclosed is a method for treatment of external secretion disorders, which comprises administering a fatty 5 acid derivative to a subject in need of said treatment. The method of the present invention is useful for treatment of at least one condition selected from h... | 07/08/2008 |
| 7390834 | Cyanophenoxy carboxylic acid compounds and compositions for delivering active agents Cyanophenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration, treatment of disease and preparation are provided as well. ... | 06/24/2008 |
| 7381731 | Pharmaceutical composition comprising citrulline Embodiments of the present invention include compositions and pharmaceutical compositions comprising citrulline and Hmg-CoA reductase inhibitors. Further embodiments relate to the use of such composition treat subjects and stimulating nitric oxide synthase. ... | 06/03/2008 |
| 7371889 | Chemical entities with multiple modes of anti-inflammatory action The invention relates to new chemical compounds that inhibit the various enzymes in the arachidonic acid pathway implicated in inflammatory disease conditions. ... | 05/13/2008 |
| 7371888 | α-(Trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl)-trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetic agents Compounds having a formula: or a pharmaceutically acceptable salt or prodrug thereof, are provided, and are useful for the treatment of metabolic disorders. ... | 05/13/2008 |
| 7368473 | Paclitaxel enhancer compounds One embodiment of the present invention is a compound represented by the Structural Formula (I): Y is a covalent bond of a substituted or unsubstituted straight chained hydrocarbyl group. In addition, Y, taken together with b... | 05/06/2008 |
| 7365091 | Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of PHEX The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula: useful as inhibitors of PHEX. These derivatives are useful fo... | 04/29/2008 |
| 7361856 | Low impact switch apparatus A platform of the type holding a plurality of normally-open electric switches in position for activation of a selected individual switch by application of a force in a direction normal to a surface of the switch by a portion of a human body. An exemplary platform ac... | 04/22/2008 |
| 7358278 | Cellular phosphorylation potential enhancing compositions preparation and use thereof A pharmaceutical composition comprising as an active phosphorylation potential enhancing substance a pharmaceutically-acceptable salt of an alpha-keto carboxylic acid thereof alone or in combination with nicatinamide and creatine and, its use and products containing... | 04/15/2008 |
| 7355134 | Practice switch apparatus A platform of the type holding a plurality of normally-open electric switches in position for activation of a selected individual switch by application of a force in a direction normal to a surface of the switch by a portion of a human body. An exemplary platform ac... | 04/08/2008 |
| 7351737 | 4-[(8-substituted)-6-chromanoyl]-and 4-[8-substituted)-chroman-6-YL-ethynyl]-benzoic and phenylacetic acids, their esters and salts having cytochrome P450RAI inhibitory activity Compounds of the formula where the variables are defined in the specification have cytochrome P450RAI-1 and P450RAI-2 inhibitory activity, and are suitable for treatment of mammals with conditions which are treatable with r... | 04/01/2008 |
| 7342028 | Medical use for tachykinin antagonists The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their preparation, pharm... | 03/11/2008 |
| 7318930 | Control methods for boring bark beetles A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described. Additional tests have shown that beetles will not infest a tree which... | 01/15/2008 |
| 7304039 | Glucose-based compounds with affinity to P-selectin The present invention relates to certain glucose-based compounds that have an affinity to P-selectin. Further, the invention relates to the use of these glucose-based compounds for the preparation of pharmaceutical compositions for the treatment of disorders associa... | 12/04/2007 |
| 7279597 | Phenyl amine carboxylic acid compounds and compositions for delivering active agents Phenyl amine carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 10/09/2007 |
| 7265143 | C-4 substituted retinoids C-4 substituted retinoic acid analogs, synthesis methods of C-4 substituted retinoic acid analogs and methods of using C-4 substituted retinoic acid analogs to treat various cancers and dermatological diseases and conditions. The C-4 substituted retinoic acid analog... | 09/04/2007 |
| 7241809 | Method for treating inflammatory bowel diseases The present invention relates to a method for treating an inflammatory bowel disease, including administering an effective amount of 1,4-dihydroxy-2-naphthoic acid or a salt thereof. ... | 07/10/2007 |
| 7229963 | Methods of using deacetylase inhibitors to promote cell differentiation and regeneration A method of enhancing progenitor cell differentiation, including enhancing myogenesis, neurogenesis, and hematopoiesis, by contacting a progenitor cell with an effective amount of a deacetylase inhibitor (DI). The progenitor cell can be part of cell culture, such as... | 06/12/2007 |
| 7223877 | Uses of hydroquinone substituted polyunsaturated fatty acids as antioxidants This invention provides novel antioxidants comprising hydroquinone substituted polyunsaturated fatty acids. Such fatty acids can be obtained from crude kombo butter and are suitable for preventing oxidation of various organic materials. In particular, the inv... | 05/29/2007 |
| 7223798 | Lipoxin Aanalogs This invention is directed to lipoxin A4 analogs of the following formula (II): wherein R1, R2, R3, R4 and R5 are described herein. These analogs are ... | 05/29/2007 |
| 7208483 | Polymeric delivery agents and delivery agent compounds Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 04/24/2007 |
| 7205001 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 04/17/2007 |
| 7199259 | Resolution of α-(phenoxy)phenylacetic acid derivatives The present invention provides a method for producing an enantiomerically enriched α-(phenoxy)phenylacetic acid compound of the formula (I): from its enantiomeric mixture, where R1 is alkyl or haloalk... | 04/03/2007 |
| 7173062 | Method for the improvement of skin wrinkles using retinyl retinoate The present invention relates to a method for the improvement of skin wrinkles using retinal retaliate. ... | 02/06/2007 |
| 7163703 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 01/16/2007 |
| 7163930 | Pharmaceutical compositions and methods relating to fucans Compositions, methods and the like comprising fucans such as fucoidan to treat surgical adhesions, arthritis, and psoriasis. ... | 01/16/2007 |
| 7164034 | Alpha2delta ligands for fibromyalgia and other disorders This invention relates to a method of treating a disorder selected from OCD, agoraphobia, agoraphobia without history of panic disorder, specific phobia, social phobia, PTSD, restless legs syndrome, premenstrual dysphoric disorder, hot flashes, and fibromyalgia by a... | 01/16/2007 |
| 7160921 | Reduction of hair growth Mammalian hair growth can be reduced by topical application of an inhibitor of fatty acid metabolism. ... | 01/09/2007 |
| 7148257 | Methods of treating mesothelioma with suberoylanilide hydroxamic acid Methods for treating mesothelioma comprising administering the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) are disclosed. ... | 12/12/2006 |
