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| Number | Title | Issue Date |
| 7928141 | Synergistic compositions and methods for enhancing potency and/or for prolonging the duration of action of anesthetics Taught is a composition for enhancing potency and/or for prolonging the duration of action of an anesthetic comprising dexamethasone, compound vitamin B, metronidazole, berberine, etamsylate, gentamicin, chymotrypsin, methylene blue trihydrate, and 5% sodium bicarbo... | 04/19/2011 |
| 7799832 | Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains The invention relates to pharmaceutical combinations of retigabine and sodium channel inhibitors for treating pains which are accompanied by an increase in muscle tone. ... | 09/21/2010 |
| 7763653 | Ternary and quaternary eutectic mixtures of local anesthetics substances The present invention describes ternary and quaternary eutectic mixtures composed by active local anesthetic substances. These eutectic mixtures possess melting point inferior to 20° C. and consist of homogeneous liquid useful in the preparation o pharmaceutical co... | 07/27/2010 |
| 7273887 | Topical anesthetic formulation The topical anesthetic formulation of the present invention is typically a solution that preferably includes lidocaine, USP as the active anesthetic ingredient with benzyl alcohol and isopropyl alcohol. This invention deals with problems commonly associated with top... | 09/25/2007 |
| 7261889 | Local anesthetic methods and kits Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. A... | 08/28/2007 |
| 7202275 | Malonamic acids and derivatives thereof as thyroid receptor ligands The present invention relates to novel thyroid receptor ligands and, more particularly, relates to malonamic acids and derivatives thereof of Formula I, which are useful in the treatment of obesity, overweight condition, hyperlipidemia, glaucoma, cardiac arrhythmias... | 04/10/2007 |
| 7109371 | Prostaglandin synthesis A process for the preparation of prostaglandin compounds having the formula (I): wherein A is selected from the group consisting of C1–C6 alkyl groups; C7–C16 aralk... | 09/19/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 6964782 | Stable hydrogen peroxide compositions, products and methods of use Disclosed are several preferred embodiments of hydrogen peroxide which are packaged with ease of use and extended shelf-life in mind. The embodiments include foam, mist, gel, and disposable towelette forms of H2O2. Optional ingredients of topic... | 11/15/2005 |
| 6958146 | Compounds to affect insect behavior and to enhance insecticides Various exemplary compounds, compositions and methods are disclosed. An exemplary composition includes an insecticide comprising a formula weight greater than approximately 220 and a compound comprising an insect stimulant and a formula weight less than approximatel... | 10/25/2005 |
| 6921539 | Antimicrobial therapeutic compositions and method of use The invention provides therapeutic antimicrobial compositions and methods for their use based on natural organic phenolic compounds combined with pharmacological agents. The antimicrobial activities of each carvacrol and thymol are believed to be enhanced, while the... | 07/26/2005 |
| 6900203 | Optically active fluorinated vasoconstrictors, methods for making them, and anesthetic formulations comprising them (R)-6F-phenylephrine, essentially free of (S)-6F-phenylephrine, and an anesthetic formulation comprising (R)-6F-epinephrin or (R)-6F-phenylephrine and having improved stability compared to formulations containing their non-fluorinated analog, are disclosed. Further ... | 05/31/2005 |
| 6881756 | Method for treating skin disorders The present invention relates to a method for reducing inflammation in the skin and/or treating inflammatory skin disorders, pain, or pruritis by topically applying a composition comprising totarol or a pharmaceutically-acceptable ester thereof. ... | 04/19/2005 |
| 6855341 | Anti-viral compositions and methods of making and using the anti-viral compositions Disclosed are anti-viral compositions containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients), and a pharmaceutical carrier. Also disclosed are methods of treating lesionous symptoms of a viral infection involvi... | 02/15/2005 |
| 6764678 | Local anesthetic methods and kits Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. A... | 07/20/2004 |
| 6730329 | Zinc containing compositions for anti-viral use One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one analgesic) at least one hydrocarbyl containing compound, and water. Anoth... | 05/04/2004 |
| 6632444 | Stabilization of ferulic acid in cosmetic compositions Cosmetic compositions containing ferulic acid at a pH of from 3 to 5, in an aqueous phase, along with a polyol, have improved storage stability and dissolution at body temperature.... | 10/14/2003 |
| 6620852 | Topical anesthetic The present invention is directed to an improved flowable anesthetic composition that does not need to be applied by an applicator. The anesthetic composition of the present invention may be applied by dripping or spraying the composition onto a wound or ... | 09/16/2003 |
| 6569901 | Alkynyl-substituted propionic acid derivatives, their preparation and use The present invention relates to compounds of formula (I) ##STR1## The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).... | 05/27/2003 |
| 6559189 | Non-toxic antimicrobial compositions and methods of use The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for de... | 05/06/2003 |
| 6534048 | Topical clonidine preparation An aqueous gel in unit dose form and suitable for topical delivery of clonidine and comprising clonidine, a water-gelling amount of a pharmaceutically acceptable gelling agent and having a pH value in the range of about 6 to about 8.5. Clonidine is presen... | 03/18/2003 |
| 6475526 | Zinc containing compositions for anti-viral use One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one analgesic) at least one hydrocarbyl containing compound, and w... | 11/05/2002 |
| 6413499 | Methods and kits for maxillary dental anesthesia by means of a nasal deliverable anesthetic Methods and systems for anesthetizing a portion or all of a patient's maxillary dental arch using a nasal delivered anesthetizing composition. The process generates anesthesia sufficient for facilitation of operative dentistry, endodontics, periodontics o... | 07/02/2002 |
| 6413961 | Irrigation solution and method for inhibition of pain and inflammation A method and solution for perioperatively inhibiting a variety of pain, inflammation, spasm and restenosis processes resulting from cardiovascular or general surgical, therapeutic and diagnostic procedures. The solution preferably includes multiple pain a... | 07/02/2002 |
| 6303621 | Method for treating cancers using a diiodo thyronine analogue having no significant hormonal activity and a vinca alkaloid and compositions comprising the same The present invention is directed to a method for treating cancers by administering a pharmaceutically effective amount of a diiodo thyronine analogue having no significant hormonal activity and a vinca alkaloid or biologically active analog thereof. The ... | 10/16/2001 |
| 6291516 | Regulators of the hedgehog pathway, compositions and uses related thereto The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting a cell with a compound, such as a polypept... | 09/18/2001 |
| 6277889 | Molluscicide formulation A molluscicide containing a non-toxic animal repellant and metaldehyde, in which the molluscicidal efficacy of the molluscicide greater than that of the molluscicide if it did not contain repellant. The repellant may be an anthranilate compound or d-puleg... | 08/21/2001 |
| 6245746 | Efflux pump inhibitors Compounds are described which have efflux pump inhibitor activity. Also described are methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds.... | 06/12/2001 |
| 6232312 | Method for treating patient having precancerous lesions with a combination of pyrimidopyrimidine derivatives and esters and amides of substituted indenyl acetic acides Combinations of substituted indenyl acetic acids and pyrimido-pyrimidine derivatives are useful in the treatment of colonic polyps and inhibiting the growth of neoplastic cells.... | 05/15/2001 |
| 6221890 | Acaricidal compositions Provided are novel acaricidal compositions which posses a synergistic acaricidal activity. As such, the acaricidal compositions of the instant invention generally contain 2-methoxycarbonyl-4-chlorotrifluoromethanesulfonanilide and 2-(2,6-difluorophen... | 04/24/2001 |
| 6177465 | Pesticidal composition A pesticidal composition which comprises 2-methoxycarbonyl-4-chlorotrifluoranethanesulfonanilide as an active ingredient and at least one ester selected from the group consisting of di-C2-8 -alkyl C4-10 -alkanedicarboxylate, tri-C | 01/23/2001 |
| 6160014 | Method for controlling acarina A method for controlling acarina which comprises setting a tablet(s) obtainable by pressing 2-methoxycarbonyl-4-chlorotrifluoromethanesulfonanilide or by pressing a composition containing 2-methoxycarbonyl-4-chlorotrifluoromethanesulfonanilide and a ... | 12/12/2000 |
| 6150409 | Adjuvants and methods for raising intracellular calcium ion concentration Adjuvants for preventing adaptation to odors comprising one or compounds having the following formula (1): ##STR1## wherein R1 is a C1 to C8 lower alkyl group or a C7 to C9 aralkyl group, and R2 is a hydrogen atom or a C1 to C8 lower alkyl group, are... | 11/21/2000 |
| 6147102 | Clonidine preparations Sympathetically maintained peripheral neuropathic pain syndromes are relieved by topically applying, to the affected region of a patient suffering from such pain, a pain relieving amount of an aqueous gel comprising clonidine, a water-gelling amount of a ... | 11/14/2000 |
| 6117877 | Method for treating painful conditions of the anal region and compositions therefor Method and composition for treating painful conditions of the anorectal region. The compositions include a combination of an -adrenergic blocker and sucralfate, a combination of -adrenergic blocker and lidocaine, and a combination of an �... | 09/12/2000 |
| 6110970 | Nitrogen-containing oxyalkylene esters and uses thereof This invention relates to nitrogen-containing oxyalkylene diester compositions for treating disease conditions including cancer and other proliferative diseases. The nitrogen-containing oxyalkylene diesters are represented by the formula ##STR1## ... | 08/29/2000 |
| 6075059 | Compositions for dental anesthesia Anesthetic compositions that achieve enhanced anesthesia of the peripheral nerves located in the mouth region of a subject or patient are provided. Such anesthetic compositions comprise water, a local anesthetic agent, and a sugar alcohol at a concentrati... | 06/13/2000 |
| 6063797 | γ-RAR antagonist ligand or -RAR agonist ligand as an apoptosis inhibitor The use of a combination of an alpha RAR receptor-specific agonist ligand and a gamma RAR receptor-specific antagonist ligand to reduce the rate of apoptosis is disclosed.... | 05/16/2000 |
| 6037371 | Insecticidal/acaricidal composition An insecticidal/acaricidal composition which comprises 2-methoxycarbonyl-4-chlorotrifluoromethanesulfonanilide and N-(2-ethylhexyl)bicyclo[2.2.1]hept-5-ene-2,3-dicarboximide as an active ingredient, and inert carrier is useful for controlling insects/acar... | 03/14/2000 |
| 5958973 | Polyhydroxy benzoic acid derivatives and their use as neuraminidase inhibitors The present invention is directed to compositions of the formula: ##STR1## wherein: R2 is H, or an alkyl group having 1 to 3 carbon atoms and 0 to 2 hydroxyls; R3 is H, or hydroxyl; R4 is H, or forms a hydrolyzable ester o... | 09/28/1999 |
