Quotables
"If you build a better mousetrap, you will catch better mice."
George Gobel
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8153689 | Pleuromutilin derivatives for the treatment of diseases mediated by microbes Disclosed are pleuromutilin derivatives of formula (I) and their use in the treatment of diseases mediated by microbes. ... | 04/10/2012 |
| 8153690 | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, card... | 04/10/2012 |
| 8106092 | Treatment of solid cancers The present invention relates generally to the field of cancer including tumor therapy. More particularly, the present invention relates to the treatment of solid cancers, including solid tumors, and the prevention or reduction of cancer metastasis, by chemoablation... | 01/31/2012 |
| 8093291 | Methods of using and compositions comprising tryptophan hydroxylase inhibitors Methods and compositions comprising tryptophan hydroxylase inhibitors are disclosed. Particular methods are directed at reducing or avoiding serotonin-mediated adverse effects associated with some drugs. ... | 01/10/2012 |
| 8093290 | Coolant solutions and compositions comprising the same A solution consisting essentially of menthyl lactate and menthol carboxamide dissolved in a solvent, such as propylene glycol, which solvent is acceptable for food, oral care or cosmetic products and a method of preparing it. ... | 01/10/2012 |
| 8071643 | Pleuromutilin derivatives for the treatment of diseases mediated by microbes A pleuromutilin derivative compound of general formula (I) ... | 12/06/2011 |
| 8067466 | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, card... | 11/29/2011 |
| 8026278 | Inhibitors of pyruvate kinase as therapeutic agents for cancer The present invention relates to compounds for the inhibition of pyruvate kinase and ATP production which are capable of inhibiting cancer cells proliferation. ... | 09/27/2011 |
| 7981930 | Compositions and kits for treating influenza Kits comprising an M2 inhibitor selected from amantadine and rimantadine; ribavirin, and a neuraminidase inhibitor (NAi) in an amount that is antivirally effective in the combination, an oral dosage form containing 75-250 mg of the M2 inhibitor, an oral dosage form ... | 07/19/2011 |
| 7964639 | Modified retinoid compounds and their uses A method of minimizing or reducing the toxicity of a retinoid having a free carboxyl group and the resulting modified retinoids are described. The method comprises the step of esterifying the carboxyl group of the retinoid with a highly sterically hindered compound,... | 06/21/2011 |
| 7951841 | Retinal derivatives and methods for the use thereof for the treatment of visual disorders Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided. ... | 05/31/2011 |
| 7915309 | Deuterium-enriched oseltamivir The present application describes deuterium-enriched oseltamivir, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. ... | 03/29/2011 |
| 7858660 | Compositions and kits for treating influenza Compositions, kits and methods are provided for the treatment or prophylaxis of influenza. ... | 12/28/2010 |
| 7795307 | Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents Carbamoyl esters inhibit cholinesterase activity and, upon hydrolysis release a pharmacologically active agent. In one embodiment, the carbamoyl ester has the following structure: Formula (I) wherein A is selected from the group consisting of an unsubstituted aryl, ... | 09/14/2010 |
| 7750044 | Dimer poly-quaternary ester compounds The present invention relates to a novel class of polymeric compounds having specific quaternized amine based upon a dimer acid reacted with an alkanolamine to make an ester quaternary compound. Dimer acid is a C-36 diacid having a cyclic structure and two amine gro... | 07/06/2010 |
| 7750043 | Modified retinoid compounds and their uses A method of minimizing or reducing the toxicity of a retinoid having a free carboxyl group and the resulting modified retinoids are described. The method comprises the step of esterifying the carboxyl group of the retinoid with a highly sterically hindered compound,... | 07/06/2010 |
| 7687541 | Prodrugs of diaryl-2-(5H)-furanone cyclooxygenase-2 inhibitors The invention encompasses the novel compounds of Formula (I) and Formula (II), which are prodrugs that convert in vivo to diaryl-2-(5H)-furanones useful in the treatment of cyclooxygenase-2 mediated diseases. These prodrugs are far more soluble in aqueous media than... | 03/30/2010 |
| 7635716 | Substituted cyclopentanes or cyclopentanones as therapeutic agents Novel compounds, and therapeutic methods, compositions and medicament related thereto are disclosed herein. ... | 12/22/2009 |
| 7622504 | Esters of 2-phenylalkanenitriles and antifungal compositions containing them Esters of 2-phenylalkanenitriles, such as 3-acetoxy-2-(2-chloro-5-(difluoromethoxy)phenyl)propanenitrile and 3-acetoxy-2-(4-chlorophenyl)propanenitrile, and compositions containing such esters, are useful as fungicides at very low concentrations. ... | 11/24/2009 |
| 7605178 | Therapeutic compounds Disclosed herein are compounds of the formula therapeutic methods, compositions, and medicaments related thereto are also disclosed. ... | 10/20/2009 |
| 7544713 | Compounds and methods for delivery of prostacyclin analogs This invention pertains generally to prostacyclin analogs and methods for their use in promoting vasodilation, inhibiting platelet aggregation and thrombus formation, stimulating thrombolysis, inhibiting cell proliferation (including vascular remodeling), providing ... | 06/09/2009 |
| 7498359 | Composition and method for preventing recurrence of stroke By using a composition for preventing onset and/or recurrence of stroke which contains ethyl icosapentate as its effective component, onset and/or recurrence of stroke is prevented, or in particular, the onset and/or recurrence of stroke in a hyperlipidemia patient ... | 03/03/2009 |
| 7442718 | Inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. T... | 10/28/2008 |
| 7429615 | Cyclohexyl prostaglandin analogs as EP-receptor agonists The invention relates to the use of novel cyclohexyl analogues of E-type prostaglandins as EP4 agonists, in general, and, in particular as ocular hypotensives. The cyclohexyl analogues used in accordance with the invention are represented by the following... | 09/30/2008 |
| 7417070 | Compounds and methods for delivery of prostacyclin analogs This invention pertains generally to prostacyclin analogs and methods for their use in promoting vasodilation, inhibiting platelet aggregation and thrombus formation, stimulating thrombolysis, inhibiting cell proliferation (including vascular remodeling), providing ... | 08/26/2008 |
| 7384978 | Compounds and methods for delivery of prostacyclin analogs This invention pertains generally to prostacyclin analogs and methods for their use in promoting vasodilation, inhibiting platelet aggregation and thrombus formation, stimulating thrombolysis, inhibiting cell proliferation (including vascular remodeling), providing ... | 06/10/2008 |
| 7365097 | Use of at least one (dihydro)jasmonic acid derivative as a desquamating agent Disclosed herein is the cosmetic use, as a desquamating agent, of at least one (dihydro)jasmonic acid derivative of a given formula. Further disclosed herein is a cosmetic method for smoothing the visible and/or tactile irregularities of the skin surface, for... | 04/29/2008 |
| 7351855 | Chemically defined non-polymeric valency platform molecules and conjugates thereof Chemically-defined, non-polymeric valency platform molecules and conjugates comprising chemically-defined valency platform molecules and biological or chemical molecules including polynucleotide duplexes of at least 20 base pairs that have significant binding activi... | 04/01/2008 |
| 7323585 | Levodopa prodrugs, and compositions and uses thereof Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed. ... | 01/29/2008 |
| 7304092 | Compounds and methods for treating tumors, cancer and hyperproliferative diseases The present invention relates to novel compounds, pharmaceutical compositions and methods for treating tumors, cancer and hyperproliferative diseases including psoriasis, genital warts and hyperproliferative cell growth diseases, including hyperproliferative keratin... | 12/04/2007 |
| 7285572 | CaSR antagonist The present invention provides a compound having a calcium-sensitive receptor antagonistic action, a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis. A compound represented by the... | 10/23/2007 |
| 7265130 | NPY Y5 antagonist The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I): wherein R1 is lower alkyl, cycloalkyl or the like, ... | 09/04/2007 |
| 7265143 | C-4 substituted retinoids C-4 substituted retinoic acid analogs, synthesis methods of C-4 substituted retinoic acid analogs and methods of using C-4 substituted retinoic acid analogs to treat various cancers and dermatological diseases and conditions. The C-4 substituted retinoic acid analog... | 09/04/2007 |
| 7262219 | Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorde... | 08/28/2007 |
| 7214710 | Permeable, water soluble, non-irritating prodrugs of chemotherapeutic agents with oxaalkanoic acids The present invention relates to the field of prodrugs of chemotherapeutic agents and method of use thereof. ... | 05/08/2007 |
| 7205435 | Type B botulism toxin inhibitors Novel compounds of general formula (I), are provided with inhibitory properties for the type B botulism toxin activity, along with methods for preparation thereof and corresponding pharmaceutical compositions. ... | 04/17/2007 |
| 7202276 | Use of 13-HODE as a regulator of vascular biocompatibility and an inhibitor of cell hyperplasia This invention relates to the regulation of vascular endothelium biocompatibility and to the inhibition of vessel wall cell and other types of cell hyperplasia following vessel wall dysfunction and/or injury. More particularly, the invention relates to the dietetic ... | 04/10/2007 |
| 7189760 | Physiological cooling compositions containing highly purified ethyl ester of N-[[5-methyl-2-(1-methylethyl) cyclohexyl] carbonyl]glycine The present invention provides, in one aspect, a substantially pure ethyl ester of N-[[5-methyl-2-(1-methylethyl)cyclohexyl]carbonyl]glycine. In another aspect, disclosed is a method for producing substantially pure ethyl ester of N-[[5-methyl-2-(1-methylethyl)cyclo... | 03/13/2007 |
| 7173062 | Method for the improvement of skin wrinkles using retinyl retinoate The present invention relates to a method for the improvement of skin wrinkles using retinal retaliate. ... | 02/06/2007 |
| 7169811 | Composition based on ethyl ester of linoleic acid and triethyl ester of citric acid for topical use in the treatment of seborrhea and acne The present invention relates to a composition for topical use for treating and improving the aesthetic conditions of the skin, which comprises, as an active ingredient, a mixture of ethyllinoleate and triethylcitrate. This composition is active in the treatment of ... | 01/30/2007 |
