A vest or belt is integrally formed with tubular, pet receiving passageways which extend around the wearer's body and terminate in pocket-like chambers for feeding and retrieval.
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| Number | Title | Issue Date |
| 7767710 | Method for treating osteoarthritis A method and composition for treating osteoarthritis with ion-channel regulators is disclosed. The ion-channel regulators are used alone or in combination with other osteoarthritis treatment agents, including but not limited to injectable agents such as viscosupplem... | 08/03/2010 |
| 7723384 | Keto lactam compounds and use thereof The invention relates to novel keto lactam compounds, hydrogenated derivatives and tautomers thereof. These compounds have valuable therapeutic properties and are particularly suited for treating diseases that respond to the modulation of the dopamine D3 ... | 05/25/2010 |
| 7442718 | Inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical features. T... | 10/28/2008 |
| 7355042 | Treatment of CNS disorders using CNS target modulators The invention is directed to compositions and methods useful for treating Central Nervous System (CNS) disorders. Furthermore, the invention provides compositions and methods of treating sleep disorders. More specifically, the invention is directed to the compositio... | 04/08/2008 |
| 7326730 | Aminoadamantane derivatives as therapeutic agents The present invention provides novel aminoadamantane derivatives, methods of making the derivatives, compositions including the novel aminoadamantane derivatives, and methods for the treatment and prevention of neurological diseases using the derivatives and composi... | 02/05/2008 |
| 7317026 | CNS target modulators The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. More specifically, the invention is directed to derivatized, e.g., ester or carboxylic acid derivatized, doxepins, and analogs thereof, useful for the treatment of sl... | 01/08/2008 |
| 7307101 | Use of 20-HETE synthesizing enzyme inhibitors as therapy for cerebral vascular disease A method for treating cerebral vascular diseases in a human or non-human animal is disclosed. The method involves inhibiting 20-HETE synthesizing enzyme activity sufficiently to increase or prevent a decrease in cerebral blood flow in the human or non-human animal. | 12/11/2007 |
| 7300662 | Drug/drug delivery systems for the prevention and treatment of vascular disease A drug and drug delivery system may be utilized in the treatment of vascular disease. A local delivery system is coated with rapamycin or other suitable drug, agent or compound and delivered intraluminally for the treatment and prevention of neointimal hyperplasia f... | 11/27/2007 |
| 7223286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/29/2007 |
| 7217286 | Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Methods of preparing intravascular stents with a polymeric coating containing macrocyclic lactone (such as rapamycin or its analogs), stents and stent graphs with such coatings, and methods of treating a coronary artery with such devices. The macrocyclic lactone-bas... | 05/15/2007 |
| 7217737 | Method and compositions for inhibiting cell proliferative disorders The present invention concerns compounds and their use to inhibit the activity of a receptor tyrosine kinase. The invention is preferably used to treat cell proliferative disorders such as cancers characterized by over-activity or inappropriate activity HER2 or EGFR... | 05/15/2007 |
| 7192607 | Formulations for the prevention or the treatment of diseases affecting mucosae or skin, or for pregnancy prevention, and an applicator for the delivery of topical formulations into mucosal cavities This invention relates to formulations for the prevention of infection and/or abnormal conditions of mucosae and/or skin caused by any pathogen and/or any disease, and more particularly for the prevention of sexually transmitted infections specially HIV and HSV. Thi... | 03/20/2007 |
| 7189757 | Treatment of sleep disorders using CNS target modulators The invention is directed to compositions used for treating Central Nervous System (CNS) disorders. In addition, the invention provides convenient methods of treatment of a CNS disorder. Furthermore, the invention provides methods of treating sleep disorders using c... | 03/13/2007 |
| 7102026 | Process for preparing and isolating -bicalutamide and its intermediates The present invention relates to a new process for the synthesis of racemic and optically active bicalutamide starting from ethyl pyruvate and methyl methacrylate. The present invention discloses processes of preparing bicalutamide intermediates including ethyl-[2-{... | 09/05/2006 |
| 7084280 | Benzotriazol-1-yl-aminoacetonitrile compounds and their use in the control of parasite disease The invention relates to benzotriazol-1-yl-aminoacetonitrile compounds and optionally the enantiomers thereof. The active ingredients have advantageous pesticidal properties. They are especially suitable for controlling parasites on warm-blooded animals. ... | 08/01/2006 |
| 7034045 | Monofluoroalkyl derivatives The present invention provides certain monofluoroalkyl derivatives useful for potentiating glutamate receptor function in a mammal and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders. ... | 04/25/2006 |
| 7022737 | Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses Mammals are treated for infections or for conditions associated with pathologically proliferating mammalian cell growth by administration of a manipulator of nitrosative stress to selectively kill or reduce the growth of the microbes or helminths causing the infecti... | 04/04/2006 |
| 7012095 | Compounds for modulating cell proliferation Novel styrylacrylonitrile compounds which are useful in treating a variety of cell proliferative disorders such as cancer are disclosed. The compounds are of Formula (I). ... | 03/14/2006 |
| 6946426 | Process to prepare aqueous formulations Provided is a method of formulating hydrophobic pesticides comprising emulsifying an aqueous phase and a water-immiscible phase to form a formulation; wherein the aqueous phase is comprised of water and optionally a freeze/thaw agent, one or more emulsifiers, or com... | 09/20/2005 |
| 6908925 | Treating skin wrinkles/fine lines with calcium channel inhibitors A regime or regimen for loosening/slackening and/or relaxing cutaneous and/or subcutaneous human skin tissue, advantageously for cosmetically/therapeutically treating skin wrinkles and fine lines, comprises administering to a candidate subject in need of such treatm... | 06/21/2005 |
| 6852328 | Method and device for protection of wooden objects proximate soil from pest invasion A method and device are disclosed which prevents the decay and deterioration of wooden objects caused by pests by using a controlled release device. This controlled release device utilizes polymers which incorporate pesticides. In the disclosed method, the controlle... | 02/08/2005 |
| 6849661 | Treatment of abnormal increases in gastrointestinal motility with (R)-verapamil The present invention is directed to methods of treating, preventing, and/or managing abnormal increases in gastrointestinal motility, and intestinal conditions that cause the same. Such conditions include, but are not limited to, irritable bowel syndrome (IBS), inf... | 02/01/2005 |
| 6800659 | Compounds for modulating cell proliferation Novel styrylacrylonitrile compounds which are useful in treating a variety of cell proliferative disorders such as cancer are disclosed. The compounds are of the Formula I: ... | 10/05/2004 |
| 6780508 | Powder particles with smooth surface for use in inhalation therapy Carriers for use in the preparation of mixtures for inhalation powders intended for pulmonary administration of micronized drugs by means of a dry powder inhaler and the method for their preparation are described. ... | 08/24/2004 |
| 6713509 | Controlled release formulation for treating COPD This invention relates to a controlled or sustained release formulation designed to deliver a PDE4 inhibitor for treating an inflammatory disease such as asthma or COPD and the like. ... | 03/30/2004 |
| 6703420 | Amino-thio-acrylonitriles as MEK inhibitors This invention relates generally to amino-thio-acrylonitriles of formula Ia or Ib: ##STR1## as MEK inhibitors, pharmaceutical compositions containing the same, and methods of using the same as for treatment and prevention of inflammatory disorders or... | 03/09/2004 |
| 6635663 | Pesticidal emulsifiable concentrate The present invention provides a low-irritant pesticidal emulsifiable concentrate comprising (a) 1 to 60% by weight of at least one pesticidal active ingredient compound selected from the group consisting of pyriproxyfen and a pyrethroid compound, (b) 2 t... | 10/21/2003 |
| 6602907 | Treatment of breast cancer Compounds of the class of 4-oxo-butenoic acid derivatives are disclosed along with the surprising use property of these compounds as a anti-tumor agents in humans against breast carcinoma, which include: 2-(N'-Fluoren-9-ylidene-hydrazino)-5,5-dimethyl-4-o... | 08/05/2003 |
| 6558696 | Desoxypeganine The invention relates to a transdermal therapeutic system (TTS) containing desoxypeganine (1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazoline) as the active component, wherein the TSS includes a back layer impermeable to desoxypeganine and an adhesive reservoir ... | 05/06/2003 |
| 6552066 | Protein tyrosine kinase inhibitors for treating osteoarthritis Disclosed is a method of treating an individual or animal with osteoarthritis. The method comprises administering to the individual or animal a therapeutically effective amount of a protein tyrosine kinase inhibitor.... | 04/22/2003 |
| 6514934 | Imidazoline -adrenergic receptor antagonist compounds in combination with nitric oxide donors, compositions and methods of use The present invention is directed to nitrosated or nitrosylated -adrenergic receptor antagonists, compositions comprising -adrenergic receptor antagonists that are optionally substituted with at least one NO or NO2 moiety and comp... | 02/04/2003 |
| 6509379 | Phenylacetic acid derivatives, process and intermediate products for their preparation, and their use as fungicides and pesticides Phenylacetic acid derivatives of the formula I ##STR1## where the variables are as disclosed herein, their salts, processes and intermediates for their preparation, and their use for controlling harmful fungi and animal pests.... | 01/21/2003 |
| 6482854 | Glaucoma treatment Elevated glutamate levels are associated with glaucoma, and damage to retinal ganglion cells can be controlled by administering to the patient a compound capable of reducing glutamate induced excitotoxicity in a concentration effective to cause reduction ... | 11/19/2002 |
| 6458846 | Ion channel modulating agents The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of oxime derivatives represented by general formula (I) that has proven useful as modulators of SKCa, IK... | 10/01/2002 |
| 6436937 | Use of desoxypeganine in the treatment of Alzheimer's dementia The invention relates to a device and method for the treatment of Alzheimer's dementia with desoxypeganine and/or a pharmaceutically acceptable acid addition salt of desoxypeganine.... | 08/20/2002 |
| 6426366 | Pharmaceutical compositions comprising tyrphostins Compounds useful for countering undesired toxic effects to cells, tissues or organs having formula (I) wherein: Ar is a group of formulae (i) or (ii), n is 0 or, when Ar has formula (i) above, then n may also be 1, R is CN, --GC(S)NH2, --C(O)NH... | 07/30/2002 |
| 6376224 | Pharmaceutical compositions for eliminating membrane-mediated cell resistance The invention relates to a pharmaceutical composition containing an inhibitor for diaphragm pumps and a photoaffinity-marked chemotherapeutic agent. Said composition is suitable for eliminating membrane-mediated cell resistance, especially membrane-mediat... | 04/23/2002 |
| 6365609 | Substituted 3,3-diamino-2-propenenitriles, their preparation and use Described are substituted cyanoenamines of formula I ##STR1## wherein Z, R1, R2 and R3 are defined in the description, compositions thereof and methods for preparing these compounds. These compounds are useful in the treat... | 04/02/2002 |
| 6362205 | Substituted 3,3-diamino-2-propenenitriles, their preparation and use Described are substituted cyanoenamines of formula I ##STR1## wherein Z, R1, R2 and R3 are defined in the description, compositions thereof and methods for preparing these compounds. These compounds are useful in the treat... | 03/26/2002 |
| 6344461 | Treating skin wrinkles/fine lines with calcium channel inhibitors A regime or regimen for loosening/slackening and/or relaxing cutaneous and/or subcutaneous human skin tissue, advantageously for cosmetically/therapeutically treating skin wrinkles and fine lines, comprises administering to a candidate subject in need of ... | 02/05/2002 |