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| Number | Title | Issue Date |
| 8067465 | Tricyclic-bis-enone derivatives and methods of use thereof Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral s... | 11/29/2011 |
| 7678830 | Tricyclic-bis-enone derivatives and methods of use thereof Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral s... | 03/16/2010 |
| 7531573 | Use of triaryl methane compounds for inhibiting unwanted cellular proliferation associated with inflammatory disease The present invention provides a class of chemical compounds useful as efficacious drugs in the treatment of sickle cell disease and diseases characterized by unwanted or abnormal cell proliferation, and in particular inflammatory diseases associated with unwanted c... | 05/12/2009 |
| 7488754 | Method for the treatment of polycystic kidney disease The present invention provides a method for treating, inhibiting the progression of, or eradicating polycystic kidney disease of in a patient in need thereof which comprises providing to said patient an effective amount of a TACE inhibitor compound alone or in combi... | 02/10/2009 |
| 7368123 | Pesticidal resin compositions and pesticidal products formed from the same According to the present invention, there is provided a pesticidal resin composition that contains (A) at least one resin selected from polyamide resins and polyacetal resins, (B) at least one compound selected from sulfone amide derivatives, sulfonic acid ester der... | 05/06/2008 |
| 7288568 | Therapeutic compositions and methods of use Compounds and methods useful for chemopreventative treatment of diseases such as cancer, Alzheimer's disease, Parkinson's disease, inflammatory bowel diseases, and multiple sclerosis. ... | 10/30/2007 |
| 7268152 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof Compounds of Formula (IA) and Formula (IB) wherein R1, R2, R3, R4, R5, and R6 are as defined herein for Formula (IA) or Formula (IB), or a tautome... | 09/11/2007 |
| 7211589 | Atisane compounds and use thereof The present invention provides a novel compound exhibiting an excellent suppressing effect to cell injury caused by radicals and neurotoxicity induced by excitatory nuerotransmitters such as glutamate. Specifically, it provides a compound represented by the followin... | 05/01/2007 |
| 7205120 | Substrates and assays for β-secretase activity The present invention is directed to novel substrates for Hu-Asp. More particularly, the invention provides peptide substrates and fusion polypeptide substrates comprising a β-secretase cleavage site. Methods and compositions for making and using the peptides are d... | 04/17/2007 |
| 7193101 | Esters with antimicrobial, bioresistant and fungal resistant properties A bromine/nitro moiety linked into the backbone of an ester or other compound over a wide range of occurrence rates provides antimicrobial, bio-resistant and fungal resistant properties for metal working fluids (MWF)s, coatings, plastics, and medical devices. The mo... | 03/20/2007 |
| 7176237 | Tricyclic-bis-enone derivatives and methods of use thereof Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral s... | 02/13/2007 |
| 7148255 | Amidoacetonitrile compounds The invention relates to compounds of formula I wherein R1, R2, R3, R4, R5, R6, R8, R8′, R9, W, X, A1 | 12/12/2006 |
| 7041844 | Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer The present invention relates to an antiandrogen compound and a method of treating prostate cancer in a patient utilizing the compound. The present invention also relates to a pharmaceutical composition which includes the compound. ... | 05/09/2006 |
| 6992106 | Anti-tumor composition The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus m... | 01/31/2006 |
| 6958146 | Compounds to affect insect behavior and to enhance insecticides Various exemplary compounds, compositions and methods are disclosed. An exemplary composition includes an insecticide comprising a formula weight greater than approximately 220 and a compound comprising an insect stimulant and a formula weight less than approximatel... | 10/25/2005 |
| 6946426 | Process to prepare aqueous formulations Provided is a method of formulating hydrophobic pesticides comprising emulsifying an aqueous phase and a water-immiscible phase to form a formulation; wherein the aqueous phase is comprised of water and optionally a freeze/thaw agent, one or more emulsifiers, or com... | 09/20/2005 |
| 6903052 | Nematicidal compositions and methods The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes that parasitize animals can also be controlled using the methods and composition of this invention. Certain of the us... | 06/07/2005 |
| 6881248 | Paint composition A paint composition containing an insecticide and piperonyl butoxide as a synergist. ... | 04/19/2005 |
| 6858588 | Nitrile glycoside useful as a bioenhancer of drugs and nutrients, process of its isolation from moringa oleifera The present invention relates to a novel nitrile glycoside of Formula I named NIAZIRIDIN and to analogues and derivatives thereof. The present invention also relates to a process for the isolation of a novel nitrile glycoside of Formula I below named NIAZIRIDIN and ... | 02/22/2005 |
| 6815465 | Heterocyclic compounds inhibiting angiogenesis The invention relates to compounds of general formula (I) wherein R stands for a group of general formula —COOR1, —CONR2R3, —CONR4CONR4R5 or —CH2OR6, wherein R1 | 11/09/2004 |
| 6730705 | Alkoximino acetic acid amides The invention relates to new alkoximinoacetic acid amides, a process for their preparation and their use as agents for combating pests. ... | 05/04/2004 |
| 6713077 | Control of shoot/foliar feeding pests with pesticide seed treatments A method of preventing damage to the shoots and foliage of a plant by a pest includes treating the seed from which the plant grows with a composition that includes at one pyrethrin or synthetic pyrethroid. In another embodiment, the pesticide is not limited to pyret... | 03/30/2004 |
| 6710071 | Difluoromethylene aromatic ethers as inhibitors of glycine transport This invention relates to a series of difluoromethylene aromatic ethers of the formula wherein ring A and X and Y are defined as in the specification, that exhibit activity as glycine transport inhibitors, their pharmace... | 03/23/2004 |
| 6620846 | Absorbable adhesive compositions A method of treating living tissue includes applying to living tissue a biocompatible adhesive composition containing at least one alkyl ester cyanoacrylate monomer and a polymerization initiator or accelerator, wherein the polymerization initiator or acc... | 09/16/2003 |
| 6608074 | Contraception method using competitive progesterone antagonists and novel compounds useful therein Competitive progesterone antagonists, including two novel steroids, viz., 11ଲ,19-[4-(cyanophenyl)-o-phenylene]-17ଲ-hydroxy-17-(3-hy droxyprop-1(Z)-enyl)-4-androsten-3-one and 11ଲ,19-[4-(3-pyridinyl)-o-phenylene]-17ଲ-hydroxy-1... | 08/19/2003 |
| 6545043 | Compounds related to natural sources and their use as biopesticides A method for suppressing target pests, comprising exposing the pests to an effective biopesticidal amount of a composition, the composition comprising a carrier and a purified glucosinolate breakdown product having a hydroxyl group attached, wherein a sta... | 04/08/2003 |
| 6538026 | Compositions useful for remodeling body spaces A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified f... | 03/25/2003 |
| 6514510 | Insecticidal and miticidal compositions An insecticidal and miticidal composition comprising as active ingredients 4-bromo-2-(4-chloro-phenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)pyrrole-3- carbonitrile and a pyrethroid insecticidal ingredient(s). This insecticidal and miticidal composition is e... | 02/04/2003 |
| 6509373 | Strain of streptomyces, and relevant uses thereof Disclosed is a new Streptomyces candidus strain, and relevant uses thereof.... | 01/21/2003 |
| 6482861 | Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer The present invention relates to an antiandrogen compound and a method of treating prostate cancer in a patient utilizing the compound. The present invention also relates to a pharmaceutical composition which includes the compound.... | 11/19/2002 |
| 6337078 | Controlled delivery compositions and processes for treating organisms in a column of water or land Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive ag... | 01/08/2002 |
| 6290992 | Foam formulation for termite control and method of application therefor A method of termite control consists of injecting a foam formulation above ground into the walls of a structure infested with termites or other undesirable pests. The inner spaces of affected walls are flooded at and above ground level to ensure that the ... | 09/18/2001 |
| 6271263 | Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives Novel derivatives of 1-aminoindan and their salts are described. Optically active 1-aminoindan derivatives are prepared by reacting a N-benzyl analog of the desired compound with an enantiomer of mandelic acid. Parkinson's disease, dementia, epilepsy, con... | 08/07/2001 |
| 6262091 | Process and agents for controlling harmful fungi Compositions for controlling harmful fungi, containing in a solid or liquid carrier a) at least one p-hydroxyaniline derivative of the formula I ##STR1## b) at least one amide compound of the formula II A--CO--NR8 --R9 (II) where the sub... | 07/17/2001 |
| 6251947 | Fungicidal carboxamides ##STR1## Compounds of Formula (I) are disclosed which are useful as fungicides, wherein Q is: (Q-1) or (Q-2), Z is (Z-1); (Z-2); (Z-3) or (Z-4); X is --O--, --CH(R11)-- or .dbd.C(R11)--; R1 is H or C1 -C | 06/26/2001 |
| 6207705 | Biopesticides related to natural sources The present invention provides novel biopesticides which can replace commercial pesticides and biopesticides which have been banned, restricted, or are being phased out, including, but not limited to chloropicrin, dichlorvos and methyl bromide. Many of th... | 03/27/2001 |
| 6207706 | Use of COMT inhibitors for the manufacture of a medicament for the prevention of diabetic vascular dysfunctions The invention is related to the use of COMT inhibitors in the treatment of diabetic vasculat dyfunctions.... | 03/27/2001 |
| 6197825 | Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective agents for trapping... | 03/06/2001 |
| 6174919 | Cyanoacrylate compositions with vinyl terminated ester groups An adhesive composition includes compounds having the following formula: ##STR1## wherein R1 is alkyl, alkoxy alkyl, anhydride, ether, ester, or amide, and R2 and R3 are hydrogen, alkyl, alkoxy alkyl, hydroxy, alkenyl, est... | 01/16/2001 |
| 6160009 | Excitatory amino acid receptor modulators Compounds of the formula ##STR1## in which R1 and R2 are as defined in the specification, and non-toxic metabolically labile ester and amides thereof are useful as modulators of metabotropic glutamate receptor function.... | 12/12/2000 |
