"Flight by machines heavier than air is unpractical and insignificant, if not utterly impossible."
Simon Newcomb, astronomer ; Said in 1902, less than two years before the first flight at Kitty Hawk
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| Number | Title | Issue Date |
| 7619000 | S-dimethylarsino-thiosuccinic acid S-dimethylarsino-2-thiobenzoic acid S-(dimethylarsino) glutathione as treatments for cancer Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenic... | 11/17/2009 |
| 7405314 | Compounds and methods for the treatment of cancer The present invention provides organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia. | 07/29/2008 |
| 7323044 | Biocidal compositions The invention provides co-solvents for preparing clear solutions of a biocidal agent known as 10, 10′-oxybisphenoxarsine (OBPA). The clear solutions are stable over a relatively broad range of temperatures and have very low Volatile Organic Carbon (VOC) content. T... | 01/29/2008 |
| 7205001 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 04/17/2007 |
| 7163703 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 01/16/2007 |
| 6995188 | S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenic... | 02/07/2006 |
| 6939566 | Microbicidal formulations and methods to control microorganisms Microbicidal formulations are described which are preferably ecologically friendly and non-toxic to mammals, and are highly effective against a broad spectrum of detrimental pathogenic microorganisms. The microbicidal formulation contains complexes having the formul... | 09/06/2005 |
| 6911471 | S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer Arsenic trioxide, an inorganic compound, is commercially available anti-cancer agent but it carries significant toxicity. Organic arsenicals, on the other hand, are much less toxic, to the extent that the methylation of inorganic arsenic in vivo into organic arsenic... | 06/28/2005 |
| 6875451 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 04/05/2005 |
| 6770674 | Mollusc repellent A mollusc repellent, which includes a substantially insoluble metal oxalate and a suitable carrier therefor, which exhibits prolonged efficacy. The mollusc repellent is environmentally friendly, being both non-phytotoxic and harmless to non-target animals, and is th... | 08/03/2004 |
| 6764692 | Method to treat laminitis and reduce dietary intake for horses A method of treating laminitis in a horse is disclosed, comprising administering to the horse a naturally chelated trace mineral composition; promoting healthy skin, hair and hoof tissue. A method of reducing dietary intake is also disclosed, comprising administerin... | 07/20/2004 |
| 6630172 | Microbicidal composition containing potassium sodium tartrate Disinfectant formulations are described which are preferably ecologically friendly and non-toxic to mammals and plants, and are highly effective against a broad spectrum of detrimental pathogenic microorganisms. The microbicidal formulation contains compl... | 10/07/2003 |
| 6521265 | Method for applying a blood clotting agent A method of arresting the flow of blood and other protein containing body fluids flowing from an open wound and for promoting wound healing. In the method, a substantially anhydrous compound of a salt ferrate is provided for a unique use which, when hydra... | 02/18/2003 |
| 6498189 | Method for induction of L-selectin shedding The invention provides anti-thiol reagents which inhibit enzyme activity of cell-associated protein disulfide isomerase (PDI) by oxidizing or blocking PDI active site vicinal thiol groups which normally participate in disulfide bond rearrangement of PDI s... | 12/24/2002 |
| 6380248 | Metal-thiols as immunomodulating agents A method is described to treat or prevent sepsis and septic shock in a subject by administering a Group V metal chelated by a complexing agent such as thiol compounds in the form of a metal:complexing agent, wherein the metal is selected from the group co... | 04/30/2002 |
| 6242009 | Microbicidal formulations and methods to control microorganisms Microbicidal formulations are described which are preferably ecologically friendly and non-toxic to mammals, and are highly effective against a broad spectrum of detrimental pathogenic microorganisms. The microbicidal formulation contains complexes having... | 06/05/2001 |
| 5889048 | Methods and compositions for treating defective cell functions A pharmaceutical formulation having immunomodulating and regenerating effect on abnormal function of cell tissue division-regulating system comprises, as an active ingredient, mercury dichloride or potassium arsenite or sodium arsenate in the amount of 0.... | 03/30/1999 |
| 5709890 | Polyaspartic acid and its analogues in combination with insecticides An insecticide composition is enhanced from the standpoint of its ability to be absorbed by insects, such as red fire ants, particularly dithiophosphate ester pesticides by the addition of a small amount of a water soluble non-aromatic polyorganic acid or... | 01/20/1998 |
| 5676923 | Substituted DTPA monoamides of the central carboxylic acid group and their metal complexes Diethylenetriaminepentaacetic acid monoamide derivatives, their complexes and complex salts, containing an element of atomic numbers 21-29, 31, 32, 39, 42-44, 49 or 57-83, pharmaceutical agents containing these compounds, their use as contrast media and p... | 10/14/1997 |
| 5629342 | Antimicrobial compositions This invention relates to antimicrobial compositions comprising a phenoxyarsine as the active antimicrobial substance and a solvent, which is a compound of the formula ##STR1## wherein R1, R2 and R3 are hydrogen or lo... | 05/13/1997 |
| 5597809 | Treatment of optic neuritis Methods of treating optic neuritis comprising administering a protective agent which inhibits glutamate-mediated retinal cell damage to a mammal at risk of developing optic neuritis.... | 01/28/1997 |
| 5565184 | Functionalized tripodal ligands for x-ray & radioactive imaging applications The present invention provides new and structurally diverse compositions comprising compounds of the general formula: ##STR1## wherein A is N or CR1, R1 is hydrogen, C1 -C8 alkyl, or C6 -C10... | 10/15/1996 |
| 5488065 | Antimicrobial compositions This invention relates to antimicrobial compositions comprising a phenoxyarsine as the active antimicrobial substance and a solvent, which is a compound of the formula ##STR1## wherein R1, R2 and R3 are hydrogen or lo... | 01/30/1996 |
| 5460751 | Compositions for the preservation of timber products Aqueous wood treating compositions, containing compounds which contain elements selected from copper, chromium and arsenic and oxyalkylene polymer additives, provide improved stability to CCA solutions containing additives. In addition, the compositions o... | 10/24/1995 |
| 5405601 | Functionalized tripodal ligands for imaging applications The present invention provides new and structurally diverse compositions for diagnostic imaging comprising compounds of the general formula: ##STR1## wherein A is N or CR1, R1 is hydrogen, C1 -C8 alkyl, or ... | 04/11/1995 |
| 5399190 | Wood preservatives A wood preservative composition including a mixture of two or more metallic soaps of long chain unsaturated fatty acids, which soaps have a metallic component selected from the group consisting of copper, zinc, chromium, iron, antimony, tin, cobalt, nicke... | 03/21/1995 |
| 5281588 | Organometallic compounds, methods for their preparation and pharmaceutical compositions containing them A method for treating trypanosomiases, leishmanioses, filariases and pneumonias caused by Pneumocystis carinii, comprising the step of administering an effective amount of an organometallic compound of the formula: ##STR1## in which: M is arseni... | 01/25/1994 |
| 5108610 | Method for isolating dithiochrome, an insulin-binding molecule with glucose metabolism-related pharmaceutical utility A process for obtaining a material possessing glucose tolerance factor activity and capable of binding with insulin including the steps of (i) contacting a eukaryotic cell mass with a mixture of water and alcohol to form a water phase and an alcohol phase... | 04/28/1992 |
| 5102657 | Microbiocidal compositions Homogeneous, stable liquid compositions are provided comprising a carrier, e.g., a plasticizer, a solvent selected from C5 to C9 aliphatic alcohols and diols, e.g., isodecyl alcohol, 2-ethyl hexanol, 2-ethyl-1, 3-hexanediol or mixtur... | 04/07/1992 |
| 4923895 | Method of treatment of human immunodeficiency virus A method of treating a patient for human immunodeficiency virus (HIV) inces administering to the individual patient intravenously a therapeutically effective dosage of oxyphenarshine (3 amino-4 hydroxyphenyl-arsineoxide hydrochloride). The dose emplyed m... | 05/08/1990 |
| 4891391 | Compositions containing antimicrobial agents in combination with stabilizers Composition of an antimicrobial agent and an antioxidant having improved antimicrobial activity compared to the antimicrobial agent alone. The preferred environment of the invention is a composition of a thermoplastic resin, an antioxidant, and an antimic... | 01/02/1990 |
| 4851398 | Bismuth containing pharmaceutical compositions The invention relates to a method for making a composition which comprises selecting at least one fatty acid or fatty ester compound having an allylic unsaturation of the type --CH.dbd.CH--CH2 --CH.dbd.CH-- or --CH.dbd.CH--CH.dbd.CH--CH2 | 07/25/1989 |
| 4814168 | Transdermal multipolymer drug delivery system A dermal compositon comprising a drug, a multi-polymer of vinyl acetate, polyethylene and optionally one or more monomers, a natural or synthetic rubber and a tackifying agent. The ratio of the multipolymer to the rubber is, respectively, about 1:1 to abo... | 03/21/1989 |
| 4761247 | Phenol-stabilized microbiocidal compositions Solutions of microbiocides in cosolvents having alkanol moieties and concentrate compositions of carriers, microbiocides and cosolvents having alkanol moieties are stabilized against UV-catalyzed oxidation by the addition of phenolic antioxidants. The sol... | 08/02/1988 |
| 4683080 | Microbiocidal compositions comprising an aryl alkanol and a microbiocidal compound dissolved therein Compositions are provided comprising a polymer processing aid, and from about 5% to about 20% by weight, based on the total weight of the composition, of a microbiocidal compound, said microbiocidal compound being present as the solute in an aryl alkanol ... | 07/28/1987 |
| 4663077 | Microbiocidal compositions comprising an aryl alkanol and a microbiocidal compound dissolved therein Provided are microbiocidal solutions comprising an aryl alkanol solvent and a microbiocidal compound dissolved therein. The solutions may be used to impart microbiocidal properties to polymer compositions.... | 05/05/1987 |
| 4656060 | Arsenical creosote wood preservatives A novel stable, homogeneous aqueous solution for application to wood surfaces is provided herein. The aqueous solution consists essentially of creosote, a conventional inorganic wood preservative component, ammonia and an oil. The oil and the creosote are... | 04/07/1987 |
| 4430329 | Synergistic treatment of adult canine heartworm with thiacetarsamide and ivermectin There is disclosed a method for the treatment of adult canine heartworm which involves treating a dog infected with adult heartworm first with thiacetarsamide and then, following a period of from 3 to 6 weeks, with ivermectin. The thiacetarsamide which ha... | 02/07/1984 |
| 4396417 | Non-Newtonian agricultural formulations Thixotropic high internal phase ratio emulsions containing biologically active agents including biocides, insecticides, fungicides, herbicides, defoliants, desiccants, seed disinfectants, growth regulators, etc., which are useful, for example, in agricult... | 08/02/1983 |
| 4049822 | Microbiocidal compositions comprising a solution of a phenoxarsine compound A microbiocidal solution for resin compositions including a glycyl phosphite or glycyl phosphonate and at least about 20 weight percent of a microbiologically active phenoxarsine. The composition can include additional solvents or dispersants or resin pla... | 09/20/1977 |