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| Number | Title | Issue Date |
| 7267822 | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation Novel oligonucleotides comprising a sequence derived by a computer program are provided for inhibiting cytotoxic activity of lymphocytic cells, inhibiting production of inflammatory cytokines and inflammatory responses associated with those cytokines, inhibiting the... | 09/11/2007 |
| 7182948 | Topical veterinary compositions and methods for the treatment and prevention of infection The present invention provides compositions and methods for the treatment of infection in a subject. More particularly, the invention provides a therapy for the treatment or prevention of mammary infections, such as bovine mastitis, comprising the topical administra... | 02/27/2007 |
| 7163918 | Iodothyronine compositions The present invention relates to compositions comprising thyroxine (T4) and triiodothyronine (T3). More specifically, the invention relates to thyroxine (T4) and triiodothyronine (T3) compositions that include a peptide carrier and thyroxine (T4) and triiodothyronin... | 01/16/2007 |
| 7029846 | Site-specific protein modification Site-specific modified proteins and method for producing site-specific modified proteins using amino acid analogs are disclosed. Methods for labeling proteins at a desired site in the presence of nucleophilic side chains, including lysine and cysteine side chains, a... | 04/18/2006 |
| 6998106 | Radioconjugation of internalizing antibodies Antibodies to cell surface ligands such as EGFRvIII can be used to therapeutically or diagnostically deliver a radiolabel to tumor cells with high selectivity. The utility of radioconjugated internalizing antibodies is limited, however, by release of the label and i... | 02/14/2006 |
| 6926908 | Formulation for inhalation Microparticles, obtainable by spray-drying a substantially pure solution of a therapeutic agent, consist essentially of the agent having its therapeutic activity when administered to the lung. In a preferred embodiment the agent is insulin. ... | 08/09/2005 |
| 6743773 | Method of using lectins for contraception, prophylaxis against diseases transmittable by sexual contact, and therapy of such diseases, and apparatus for administering lectins In order to prevent conception and/or the spread of sexually transmitted diseases (STD's) one or more lectins capable of binding sperm and/or the pathogenic microorganisms responsible for STD's are administered to the vagina prior to sexual intercourse. The lectins ... | 06/01/2004 |
| 6642202 | Egg having active oxygen eliminating ability and method of producing same The object of the present invention is to allow an egg originally having almost no active oxygen eliminating ability, to strongly possess an active oxygen eliminating ability. It was found that an egg containing a high level of iodine (4.2 ppm or more) ha... | 11/04/2003 |
| 6630123 | Method to enhance tissue accumulation of radiolabeled compounds Administration of a radioisotopic compound by infusion over a period of time greater than two hours, preferably greater than twelve hours, greatly increases the maximum radioactivity that accumulates in the target cell. The efficacy of the administration ... | 10/07/2003 |
| 6451349 | Spray-drying process for the preparation of microparticles Microparticles, obtainable by spray-drying a substantially pure solution of a therapeutic agent, consist essentially of the agent having its therapeutic activity when administered to the lung. In a preferred embodiment the agent is insulin.... | 09/17/2002 |
| 6251860 | Pharmaceutical preparations The present invention relates to pharmaceutical compositions of transferrin and to the manufacture of such preparations. The present invention concerns specifically a pharmaceutical composition of apotransferrin, the iron-free form of transferrin, wherein... | 06/26/2001 |
| 6190696 | Stabilized thyroxine medications Thyroxine medications which include combinations of levothyroxine, and/or liothronine, or dextrothyroxine, or thyroid, and one or more iodine salts, or iodine donor compounds are described, which produce a stable thyroxine medication, with a long shelf li... | 02/20/2001 |
| 6015836 | Chemical disinfectant employing dual chain quaternary ammonium compounds with iodine A new and improved formulation of a dual chain quaternary ammonium chloride compound and iodine/potassium iodide complex to serve as a disinfectant and sanitizer on surfaces and tissue as well as being utilized as an immersion solution in health care area... | 01/18/2000 |
| 5951989 | Method for the treatment of dry skin A method for the treatment of dry skin by applying an effective amount of thyroid hormone in a pharmaceutically acceptable carrier to the skin.... | 09/14/1999 |
| 5849291 | Opthalmic non-irritating iodine medicament The present invention relates to an enzymatically generated iodine microbicide for the inactivation of pathogenic organisms that are contaminants in or on sensitive biological materials such as the human eye. The biocidal agent from the enzymatic reaction... | 12/15/1998 |
| 5780509 | Compound bearing two, 2,6-diiodophenol-4-YL groups and diagnostic drug for iodine allergy A compound bearing at least two 2,6-diiodophenyl-4-yl groups represented by formula (IV), particularly a polymer composed of two to eight iodinated tyrosine molecules condensed with each other. This compound is useful as a diagnostic drug for iodine aller... | 07/14/1998 |
| 5767227 | Iodothyronine polymers Iodothyronine polymers having a plurality of recurring units of formula I ##STR1## in which A is iodo and B, C and D are independently H or iodo are described. Polymers in which A and C are iodo and B and D are independently H or iodo and in which su... | 06/16/1998 |
| 5746998 | Targeted co-polymers for radiographic imaging A radiographic imaging agent including a plurality of block copolymers forming a micelle, the block copolymers including a hydrophilic polymer linked to a hydrophobic polymer, and the hydrophobic polymer including a backbone incorporating radiopaque molec... | 05/05/1998 |
| 5739116 | Enediyne derivatives useful for the synthesis of conjugates of methyltrithio antitumor agents This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The... | 04/14/1998 |
| 5688770 | Antiglaucoma compositions and methods The present invention relates to ophthalmo-logical pharmaceutical compositions comprising a renin inhibitor and to methods for using said composition in the treatment of glaucoma.... | 11/18/1997 |
| 5648075 | Iodine based germicidal composition The present invention relates generally to an enzymatically generated iodine microbiocide and more specifically to the use of such a microbiocide for the inactivation of pathogenic organisms that are contaminants in sensitive biological materials. The bio... | 07/15/1997 |
| 5639481 | Method for the therapeutic treatment of a mammalian eye using an admixed composition containing free molecular iodine The present invention relates generally to an enzymatically generated iodine microbicide and more specifically to the use of such a microbiocide for the inactivation of pathogenic organisms that are contaminants in or on sensitive biological materials suc... | 06/17/1997 |
| 5567410 | Composotions and methods for radiographic imaging A radiographic imaging agent including a plurality of block copolymers forming a micelle, the block copolymers including a hydrophilic polymer linked to a hydrophobic polymer, and the hydrophobic polymer including a backbone incorporating radiopaque molec... | 10/22/1996 |
| 5538726 | Method and compositions for delivering cytotoxic agents to cancer A method of treating solid tumor cancer in a living being by prolonging the time a therapeutically effective agent remains in the tumor. The method comprises the steps of selecting particles of an aggregated protein and injecting them interstitially into ... | 07/23/1996 |
| 5447710 | Method of making nanoparticulate X-ray blood pool contrast agents using high molecular weight nonionic surfactants The present invention is directed to a composition comprised of nanoparticles containing an x-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier asso... | 09/05/1995 |
| 5352666 | Antiglaucoma compositions and methods The present invention relates to ophthalmological pharmaceutical compositions comprising a renin inhibitor and to methods for using said composition in the treatment of glaucoma.... | 10/04/1994 |
| 5340564 | Formulations comprising olin 10-G to prevent particle aggregation and increase stability This invention discloses a composition comprised of nanoparticles having p-isononylphenoxypoly (glycidol) as a surface modifier adsorbed on the surface thereof. In preferred embodiments, the p-isononylphenoxypoly (glycidol) provides resistance to particle... | 08/23/1994 |
| 5326552 | Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants The present invention is directed to a composition comprised of nanoparticles containing an X-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier asso... | 07/05/1994 |
| 5186922 | Use of biodegradable microspheres labeled with imaging energy constrast materials The invention relates to an inexpensive and easy to use method of visualizing an arterial circulation, using biodegradable microspheres which are permeated with an imaging energy absorbent contrast material, such as an X-ray absorbent material, which enab... | 02/16/1993 |
| 5168102 | Endocrine manipulation to improve body composition of poultry The body composition of poultry is improved by a hormonal strategy that includes the step of increasing plasma levels of thyroid hormone to about 150-250% (normal endogeneous T3 hormone level=100%) during essentially the finishing phase (e.g., ... | 12/01/1992 |
| 5128136 | Wound healing kit comprised of gelable collagen A stabilized collagen gel is disclosed as are methods of making this collagen gel which is useful as a wound dressing to prevent dehydration of the subject being treated and infection of the wound. The collagen gel of the invention is stabilized by combin... | 07/07/1992 |
| 5093114 | Treatment of human viral infections Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'... | 03/03/1992 |
| 5081106 | Wound dressing protocol utilizing collagen gelatin formed with iodine A stabilized collagen gel is disclosed as are methods of making this collagen gel which is useful as a wound dressing to prevent dehydration of the subject being treated and infection of the wound. The collagen gel of the invention is stabilized by combin... | 01/14/1992 |
| 5000935 | Treatment method utilizing transferrin-radioiodine conjugate Conjugates of transferrin with a radioactive isotope of iodine are utilized to treat cancer in animals.... | 03/19/1991 |
| 4923890 | Difluoro keto compounds and their use as HLE inhibitors The invention relates to selected difluoro compounds of formulae Ia, Ib and Ic (set out hereinafter) which are useful as inhibitors of human leukocyte elastase.... | 05/08/1990 |
| 4839080 | Antibacterial iodophor soap base composition and method of making same An antibacterial soap composition and method of making the same in which the product is especially useful for wound cleansing, pre-operative cleansing of surgical sites, sanitizing, surgical scrubbing and the like containing an iodophore as its essential ... | 06/13/1989 |
| 4783401 | Viable cell labelling Methods for reproducibly labelling viable cells with cyanine dyes that do not significantly affect cell viability. Applications for labelled cells include using labelled red blood cells to distinguish post-transfusional bleeding from immunologic reaction ... | 11/08/1988 |
| 4761421 | Use of certain compounds in livestock food as growth promotants for better feed utilization and improved carcass composition A method is described in which the feed utilization by livestock is improved by the incorporation in the feed or drinking water of the said livestock of certain compounds, with resultant increase in body weight, decrease in body fat and increase in body p... | 08/02/1988 |
| 4169141 | 1-Peptidyl derivatives of di-O-aminoglycosyl-1,3-diaminocyclitol antibacterial agents Disclosed herein are di-O-(aminoglycosyl)-1,3-diaminocyclitol antibacterial agents having on the 1-N-position of the 1,3-diaminocyclitol moiety a dipeptidyl or a tripeptidyl substituent. The compounds are useful antibacterial agents, as are their non-toxi... | 09/25/1979 |
| 4148884 | Certain lodophor disinfectant compositions Stable microbicidal disinfectant compositions comprising a complex of a halogen, a nonionic surface-active agent, and an -onium salt of an alkyl amine characterized by a negative reaction to standard tests for free halogen, no loss of halogen when boiled ... | 04/10/1979 |
