Class 514/485 - The ring is a benzene ring

Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the ring is a benzene ring.
No. of patents: 149
Last issue date: 09/14/2010

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Number	Title	Issue Date
7795304	Histone deacetylase inhibitors The invention relates to hydroxamic acid derivatives having carbamate linkage with the structural formula that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular prol...	09/14/2010
7659309	Polymorphic forms of (1-{3-[3-(4-cyano-3-methoxy-phenyl) ureido]-phenyl}-ethyl)-carbamic acid-2-cyano-1-ethyl-ethyl ester The present invention relates to polymorphic forms of (1-{3-[3-(4-cyano-3-methoxy-phenyl)ureido]-phenyl}-ethyl)-carbamic acid-2-cyano-1-ethyl-ethyl ester, processes therein, pharmaceutical compositions thereof, and uses therewith. ...	02/09/2010
7544712	Treatment of coronavirus infection A method for treating coronavirus infection by administering to a subject in need of the treatment an effective amount of one or more of the following compounds: aklavin, sanguinarine, amiodarone, chlorpromazine, clomiphene, dihydroergotamine, dipyridamole, emetine,...	06/09/2009
7365196	Sulphonamido-substituted bridged bicycloalkyl derivatives A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of and/or prevention of Alzheimer's disease. ...	04/29/2008
7342039	Substituted indole oximes The present invention relates to substituted indole oximes and methods of using them. ...	03/11/2008
7329689	Monohydrate hydrochloride of the 4-hydroxycarbamoyl-phenyl)-carbamic acid (6-diethylaminomethyl-naphtalen-2-yl) ester A compound having formula (I) and a process for the preparation thereof are described. ...	02/12/2008
7244755	Hydroxypropylamines Disclosed are compounds of formula I: and the pharmaceutically acceptable salts thereof wherein the variables RN, R1, R2, R3, RP and RC are define...	07/17/2007
7230000	Methods and compositions utilizing quinazolinones Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity ...	06/12/2007
7192965	4-(3,3-dihalo-allyloxy)phenoxy alkyl derivatives Compounds of formula wherein A1, A2 and A3 are each independently of the others a bond or a C1–C6alkylene bridge; A4 i...	03/20/2007
7161034	Lidocaine analogs and methods of making and using same Lidocaine analogs, latex particle-analog conjugates, and methods of making and using the same. The analogs have the formula: wherein Z comprises a nucleophilic group and optiona...	01/09/2007
7138122	Therapeutic systems A compound comprising a target cell-specific portion and human NAD(P)H:quinone reductase 2 (NQO2) or a variant or fragment or fusion or derivative thereof which has substantially the same activity as NQO2 towards a given prodrug, or a polynucleotide encoding said NQ...	11/21/2006
7135465	Sustained release beadlets containing stavudine Extended dosage forms of stavudine are provided comprising beadlets formed by extrusion-spheronization and coated with a seal coating. The beadlets are also coated with a modified release coating such that a hard gelatin capsule containing such beadlets will provide...	11/14/2006
7129268	Peroxisome proliferator activated receptor-active arylene acetic acid derivatives Novel compounds of the general formula (I), wherein Ar, R1, R2, X1, X2, Y1, Y, and Z are as defined in the specification, the use of these compounds as pharm...	10/31/2006
7045512	Fungicidal phenoxyphenylhydrazine derivatives A fungicidally active compound of the formula: a) wherein Q is —NY—NH—, —N═N—, or X is oxygen...	05/16/2006
7015345	Propionic acid derivatives A compound represented by the following formula (1) or a salt thereof: wherein R1 represents a C1-12 alkyl group, phenyl group, 1-naphthyl group and the like, R2 represents a C2-12 ...	03/21/2006
6972292	Certain substituted polyketides, pharmaceutical compositions containing them and their use in treating tumors The present invention relates to certain substituted polyketides of formula I, wherein A, B, C, D, E, F and m are as defined herein, pharmaceutical compositions containing said compounds, and the use of said compounds ...	12/06/2005
6936719	Biaryl compounds as serine protease inhibitors Compounds of formula (I) are useful as inhibitors of trypsin like serine protease enzymes such as thrombin, factor VIIa, factor Xa, TF/FVIIa, and trypsin. These compounds could be useful to treat and/or prevent clotting disorders, and as anticoagulating agents. ...	08/30/2005
6924312	Taxol enhancer compounds Disclosed is a compound represented by the Structural Formula (I): Y is a covalent bond, a phenylene group or a substituted or unsubstituted straight chained hydrocarbyl group. In addition, Y, ...	08/02/2005
6867231	Therapeutic systems A compound comprising a target cell-specific portion and human NAD(P)H:quinone reductase 2 (NQO2) or a variant or fragment or fusion or derivative thereof which has substantially the same activity as NQO2 towards a given prodrug, or a polynucleotide encoding said NQ...	03/15/2005
6831196	Urokinase inhibitors The invention relates to a highly active, highly specific urokinase inhibitor which is suitable for therapeutic applications and can be synthesized in an extremely simple manner. Surprisingly, it was found that amidino benzylamine derivatives, especially 4-amidino-b...	12/14/2004
6825224	Prodrugs of carbamate inhibitors of IMPDH The present invention relates to novel compounds, methods of preparing these compounds, and pharmaceutical compositions comprising these compounds. These compounds are carbamate prodrugs that convert to active inhibitors of the IMPDH enzyme in vivo. The compounds an...	11/30/2004
6818765	Benzene-sulphonamide derivatives and their uses Benzene-sulphonamide derivatives complying with the general formula (I): in which the different symbols have different meanings, their optical isomers and the salts pharmacologically acceptable of these derivatives, as...	11/16/2004
6812229	Carbamate derivative and agricultural/horticultural fungicide It is to provide a novel fungicide having high controlling effects on plant diseases particularly on wheat powdery mildew and cucumber gray mold, without ill effects on crops. A carbamate derivative represented by the general formula [I]	11/02/2004
6777572	Use of propargyl glycine amino propargyl diol compounds for treatment of renal failure Compounds characterized generally as propargyl glycine amino propargyl diol derivatives are useful for treatment of renal failure. Compounds of particular interest are those of Formula I wherein A is selected from CO and...	08/17/2004
6765021	2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia This invention provides compounds of formula I having the structure wherein: B, D, C, and R1 as defined herein. ...	07/20/2004
6756511	Gamma-secretase inhibitors Gamma-secretase inhibitors, useful in the treatment or prevention of Alzheimer's disease, are disclosed. The preferred compounds have, as the central portion of the molecule, the structure (a) and are di-astereoisomers of known protease inhibitors.	06/29/2004
6753298	Agents for combating Neospora spec Compositions for controlling diseases caused by protozoans of the genus Neospora, which are characterized in that they comprise one or more active compounds which inhibit the microtubulin system of plants. ...	06/22/2004
6716875	Synergistic therapeutic compositions of ACE and renin inhibitors and methods This invention relates to compositions and methods for achieving a therapeutic effect such as lowering blood pressure and treating congestive heart failure in a mammal. More specifically, this invention relates to synergistic compositions comprising amounts of at le...	04/06/2004
6696488	(Hydroxyethyl)ureas as inhibitors of alzheimer's ଲ-amyloid production Novel (hydroxyethyl)ureas are described. These compounds are effective inhibitors of certain aspartyl proteases, notably secretases involved in the enzymatic cleavage of amyloid precursor protein (APP) to yield amyloid-ଲ peptide. Methods are provide...	02/24/2004
6686391	N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions Methods for the treatment of cancers or viral infections in mammals are disclosed that include administration of an N-chlorophenylcarbamate, or an N-chlorophenylthiocarbamate, or a salt thereof. Such compounds may be used in combination with a chemotherap...	02/03/2004
6589986	Methods of treating anxiety disorders This invention provides methods for treating, preventing or inhibiting anxiety, anxiety-related conditions and phobias in a mammal using compounds of the formula: ##STR1## wherein: R1 is H, alkyl, alkanoyl or the radical Ar; R2 is H ...	07/08/2003
6534546	Aniline derivatives possessing an inhibitory effect of nitric oxide synthase Compounds represented by the general formula (1): ##STR1## (where R1 is SR6 or NR7 R8, where R6 is typically an alkyl group having 1-6 carbon atoms, R7 is a hydrogen atom, an alkyl group having ...	03/18/2003
6498188	Methods of treatment for cancer or viral infections Methods for the treatment of cancers or viral infections in mammals are disclosed that include administration of an N-chlorophenylcarbamate, or an N-chlorophenylthiocarbamate, or a salt thereof. Such compounds may be used in combination with a chemotherap...	12/24/2002
6458781	Substituted diarylalkyl amides as calcium channel antagonists The present invention provides compounds that block calcium channels and have the Formula I: ##STR1## The present invention also provides pharmaceutical compositions containing the compounds of Formula I and methods of using them to treat stroke, cer...	10/01/2002
6416789	Synergistic combination of fungicides to protect wood and wood-based products from fungal decay, mold and mildew damage A wood treatment material having a synergistic combination of fungicides including boron-containing compounds, organo-iodine compounds and amine-oxides is provided. This combination is shown to be especially effective in providing resistance to decay, mol...	07/09/2002
6395763	Prodrugs of carbamate inhibitors of IMPDH The present invention relates to novel compounds, methods of preparing these compounds, and pharmaceutical compositions comprising these compounds. These compounds are carbamate prodrugs that convert to active inhibitors of the IMPDH enzyme in vivo. The c...	05/28/2002
6375999	Methods for treating potatoes A sprout inhibitor for potatoes is introduced into a potato storage facility as a gas phase carried in an air stream. The liquid sprout inhibitor may be heated prior to injection into a flowing air stream or a large surface area of the liquid sprout inhib...	04/23/2002
6297275	Method for controlling fungi using phenylhydrazine derivatives A method for controlling fungi using a phenylhydrazine derivative compound of the formula: ##STR1## wherein: X is phenyl, phenylalkoxy, phenoxy, or benzyl, alone or in combination with one or more halogen, alkyl, or alkylthio; Y is hydrogen, alkanoyl, hal...	10/02/2001
6274586	Combatting parasitic fungi with a combination of an active agent inhibiting respiration in the cytochrome complex III and of fenazaquine The present nvention relates to compositions for controlling harmful fungi which comprise, as active ingredients, at least one compound which inhibits respiration on the cytochrome complex III and fenazaquin. The compositions according to the invention ar...	08/14/2001
6232339	Phenylcarbamates, their preparation, and compositions comprising them Phenylcarbamates of the formula I ##STR1## where: R1 is C1 -C4 -alkyl; R2 is cyano, nitro, trifluoromethyl, halogen, C1 -C4 -alkyl and C1 -C4 -alkoxy; m is 0, 1 or 2, where...	05/15/2001

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Class 514/485 - The ring is a benzene ring