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| Number | Title | Issue Date |
| 8022104 | Formulations of ladostigil tartrate Disclosed are formulations of ladostigil tartrate, including pharmaceutical compositions, process for the manufacture, and use thereof. ... | 09/20/2011 |
| 7625946 | Propargylated aminoindans, processes for preparation, and uses thereof This invention provides compounds having the structure: wherein R1 is methyl and R2 is H, or R1 is ethyl and R2 is hydroxymethyl; R3 is H or propargyl; ... | 12/01/2009 |
| 7618999 | Process of obtaining taxosteroids and precursors thereof The present invention relates to a process of obtaining taxosteroids and precursors thereof from the hydrindane bicyclic ring system. The compounds have a tetracyclic system which combines the structural characteristics of taxanes, such as the bicyclo[5.3.1]undecane... | 11/17/2009 |
| RE39616 | Aminoindan derivatives This invention is directed to compounds of the following formula: wherein when a is 0, b is 1 or 2; when a is 1, b is 1, m is from 0-3, X is O or S, Y is halogeno, R1 is hydrogen C1-4 alkyl, R2 is... | 05/08/2007 |
| 7169804 | Antibacterial mutilins A compound of formula (I) wherein R and R2 together with the nitrogen atom to which they are attached form pyrrolidinyl or piperidinyl, R1 is a group of formula (II) R3 and R′3 are hydrogen, deuterium or halogen, R4... | 01/30/2007 |
| 7160907 | Pleuromutilin derivatives Pleuromutilin compounds of the formula: are of use in anti-bacterial therapy. ... | 01/09/2007 |
| 7115767 | Tetraline derivatives as ghrelin receptor modulators The present invention is related to compounds of formula (I), or a therapeutically suitable salt or prodrug thereof, the preparation of the compounds, compositions containing the compounds and the use of the comp... | 10/03/2006 |
| 7060727 | Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof The present invention relates generally to prodrugs of fused GABA analogs, pharmaceutical compositions of prodrugs of fused GABA analogs, methods of making prodrugs of fused GABA analogs and methods of using prodrugs of fused GABA analogs and pharmaceutical composit... | 06/13/2006 |
| 6974878 | Catalyst ligands, catalytic metal complexes and processes using same A new ligands that include a benzene ring in the backbone can be combined with a metal or metal precursor compound or formed into a metal-ligand complex catalyze a number of different chemical transformations, including olefin polymerization reactions. The ligands, ... | 12/13/2005 |
| 6737547 | Compositions containing and methods of using N-acyl-1H-aminoindenes The present invention provides novel aminoindenes having the structure: wherein n is 1 or 2, R1 is hydrogen, linear or branched chain C1-C8 alkyl or linear or branched chain C1... | 05/18/2004 |
| 6717012 | Antioxidant nitroxides and nitrones as therapeutic agents The invention provides novel adamantane compounds having one of the following formulas: wherein: R1 and R3 are H, OH, alkyl, cycloalkyl, amino or aryl, and can be the same or different; | 04/06/2004 |
| 6538025 | Aminoindan derivatives This invention is directed to compounds of the following formula: ##STR1## wherein when a is 0, b is 1 or 2; when a is 1, b is 1, m is from 0-3, X is O or S, Y is halogeno, R1 is hydrogen C1-4 alkyl, R2 is hydrogen, C... | 03/25/2003 |
| 6469056 | Pharmaceutically active compounds, their preparation and use as ECE-inhibitors Pharmaceutically active compounds are prepared as described and used to produce pharmaceutical preparations for treating diseases.... | 10/22/2002 |
| 6416789 | Synergistic combination of fungicides to protect wood and wood-based products from fungal decay, mold and mildew damage A wood treatment material having a synergistic combination of fungicides including boron-containing compounds, organo-iodine compounds and amine-oxides is provided. This combination is shown to be especially effective in providing resistance to decay, mol... | 07/09/2002 |
| 6410574 | Fungicidal composition and method for using the same The present invention relates to a fungicidal composition obtained by mixing a 1,2,3-thiadiazole derivative of general formula (I) useful as a plant disease controller with at least one fungicide selected from the compounds having a fungicidal activity ag... | 06/25/2002 |
| 6303650 | Aminoindan derivatives This invention is directed to compounds of the following formula ##STR1## wherein when a is O, b is 1 or 2; when a is 1, b is 1, m is from 0-3 X is O or S, Y is halogeno, R1 is hydrogen C1-4 alkyl, R2 is hydrogen, C1-... | 10/16/2001 |
| 6303569 | Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents The present invention is directed to double prodrugs containing polymeric-based transport forms. These polymeric compounds comprise the formula: ##STR1## wherein: B is H, OH, OSiR13, a residue of an amine-containing target moiety or a resi... | 10/16/2001 |
| 6290992 | Foam formulation for termite control and method of application therefor A method of termite control consists of injecting a foam formulation above ground into the walls of a structure infested with termites or other undesirable pests. The inner spaces of affected walls are flooded at and above ground level to ensure that the ... | 09/18/2001 |
| 6239175 | Carbamoyloxy derivatives of mutiline and their use as antibacterials Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and derivatives thereof, in which R1 is ethyl or vinyl, Y is a carbamoyloxy group, in which the N-atom is unsubstituted, or mono- or di-substituted, are useful in the... | 05/29/2001 |
| 6180095 | Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents The present invention is directed to double prodrugs containing polymeric-based transport forms. These polymeric prodrugs are preferably of the formula: ##STR1## wherein: L1 is a bifunctional linking moiety; G is H or ##STR2## where B is H... | 01/30/2001 |
| 6080784 | Protein kinase C modulators N Compositions with protein kinase C-modulatory, anti-inflammatory and other activities are disclosed.... | 06/27/2000 |
| 6020368 | Carbamoyloxy derivatives of mutiline and their use as antibacterials Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and derivatives thereof, in which R1 is ethyl or vinyl, Y is a carbamoyloxy group, in which the N-atom is unsubstituted, or mono- or di-substituted, are useful in the... | 02/01/2000 |
| 6011045 | Vitronectin receptor antagonists, their preparation and their use The present invention relates to compounds of the formula I A--B--D--E--F--G (I) in which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds... | 01/04/2000 |
| 5981564 | Water-soluble derivatives of paclitaxel, method for producing same and uses thereof The invention relates to new paclitaxel derivatives showing an increased solubility in water. More particularly, the invention relates to glutarylpaclitaxel, glutarylpaclitaxel 6-aminohexanol glucuronide and to different amino acid derivatives of the glut... | 11/09/1999 |
| 5955501 | Protein kinase C modulators O Compounds having anti-inflammatory and other activities are disclosed. The compounds are derived from phorboids of the diterpene- and benzolactam-classes.... | 09/21/1999 |
| 5922761 | Methods for in vivo reduction of iron levels and compositions useful therefor In accordance with the present invention, there are provided methods for the in vivo reduction of free iron ion levels in a mammalian subject. The present invention employs a scavenging approach whereby free iron ions are bound in vivo to a suitable physi... | 07/13/1999 |
| 5922771 | Benzocycloalkene compounds, their production and use A compound of the formula ##STR1## wherein R1 and R2 independently represent H or an optionally substituted hydrocarbon group; R3 represents an optionally substituted hydrocarbon group; R4 represents H or a... | 07/13/1999 |
| 5773469 | Diaryl antimicrobial agents The invention relates to diaryl antimicrobial compounds of the general formula: ##STR1## where G, E L, J, q, m, X, Ar, W, p, n and A are as described herein, pharmaceutical compositions containing the compounds, methods for their production and ... | 06/30/1998 |
| 5733924 | DC 107 derivatives and treatment methods DC107 derivatives represented by the formula (I): ##STR1## or pharmacologically acceptable slats thereof, wherein R1 is hydrogen, lower alkoxyalkyl, aralkyloxyalkyl, lower alkoxyalkoxyalkyl, lower alkoxyalkoxyalkoxyalkyl, aralkyl, tetrah... | 03/31/1998 |
| 5709890 | Polyaspartic acid and its analogues in combination with insecticides An insecticide composition is enhanced from the standpoint of its ability to be absorbed by insects, such as red fire ants, particularly dithiophosphate ester pesticides by the addition of a small amount of a water soluble non-aromatic polyorganic acid or... | 01/20/1998 |
| 5688817 | Di(aromatic) compounds and their use in human and veterinary medicine and in cosmetics Di(aromatic) compounds corresponding to the following formula: ##STR1## in which: Ar represents either ##STR2## n=1 or 2 or: ##STR3## X represents a divalent radical, Z represents O, S or a divalent radical, and R1, R2 | 11/18/1997 |
| 5646133 | Polyaspartic acid and its analogues in combination with insecticides An insecticide composition is enhanced from the standpoint of its ability to be absorbed by insects, such as red fire ants, particularly dithiophosphate ester pesticides by the addition of a small amount of a water soluble non-aromatic polyorganic acid or... | 07/08/1997 |
| 5519043 | Fluorenyl derivatives The compound having the formula: ##STR1## and a method of treating an inflammatory condition comprising administering to an animal in need of such treatment an effective amount of at least one compound represented by the formula.... | 05/21/1996 |
| 5504109 | Susbstituted amino acid amide derivatives their preparation and use Amino-acid derivatives of the formula ##STR1## in which R1 represents alkyl, alkenyl, alkinyl, halogenoalkyl, halogenoalkenyl, halogenoalkinyl, cycloalkyl, cycloalkenyl, unsubstituted or substituted aryl, unsubstituted or substituted aralk... | 04/02/1996 |
| 5472973 | Fluorenyl derivatives as anti-inflammatory agents The compound having the formula: ##STR1## and a method of treating an inflammatory condition comprising administering to an animal in need of such treatment an effective amount of at least one compound represented by the formula.... | 12/05/1995 |
| 5464866 | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases Substituted hydrindanes and their use in controlling angiogenesis-dependent diseases in warm blooded animals are disclosed.... | 11/07/1995 |
| 5385917 | Carboxylic acid derivatives Carboxylic acid derivatives of the formula: ##STR1## are provided, which are useful for treatment of androgen dependent diseases.... | 01/31/1995 |
| 5356931 | Use of -arylacrylic derivatives for controlling pests Alpha-Arylacrylic acid derivatives of the general formula I ##STR1## where X is ethylene or ethenylene; n is 0 or 1; m is 0, 1, 2, 3 or 4; R1 is cyano, cyanato, thiocyanato, nitro, hydroxyl, carboxyl, haloalkyl, haloalkoxy, unsubstituted or sub... | 10/18/1994 |
| 5349112 | Cyclic anti-tumor promoter compounds, compositions and methods for production and use Novel cyclic anti-tumor promoter compounds and therapeutic compositions are disclosed, along with method for their production and use as anti-cancer and cancer-prevention agents.... | 09/20/1994 |
| 5290774 | Photostabilizing method for ophthalmic solutions and the resulting ophthalmic solutions therefrom This invention relates to a photostabilizing method for ophthalmic solutions and the resulting ophthalmic solutions therefrom. The stabilization is attained by adding polyhydric alcohol and boric acid, and/or sodium borate to ophthalmic solutions which co... | 03/01/1994 |
