A forehead support apparatus for resting a standing users forehead against a wall above a bathroom commode or urinal or beneath a showerhead.
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| Number | Title | Issue Date |
| RE43372 | C16 unsaturated FP-selective prostaglandins analogs Compounds having the general structure: which are useful for the treatment of a variety of diseases and conditions, such as bone disorders. ... | 05/08/2012 |
| 8153683 | Methods of treatment using a prodrug of an excitatory amino acid This invention relates to synthetic excitatory amino acid prodrugs and processes for their preparation. The invention further relates to methods of using, and pharmaceutical compositions comprising, the compounds for the treatment of neurological disorders and psych... | 04/10/2012 |
| 8153682 | Sulfonamides as TRPM8 modulators Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein A, B, G, Y, R1... | 04/10/2012 |
| 8148422 | Sulfonamides as TRPM8 modulators Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) and Formula (II) as follows: wherein Y, R | 04/03/2012 |
| 8143307 | Benzothiophen-2-carbonylguanidine derivatives, preparation thereof, and pharmaceutical composition containing the same The present invention is related to benzothiophen-2-carbonylguanidine derivatives, a preparation method thereof, and pharmaceutical compositions containing the same. The derivatives have potent inhibitory effect on the sodium/hydrogen exchanger NHE-I, improve the fu... | 03/27/2012 |
| 8129425 | Small organic molecule regulators of cell proliferation The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a hedgehog agonist, such as the compounds depicted in FIGS. 32 and 33. In certain embodim... | 03/06/2012 |
| 8101651 | Compounds with activity at estrogen receptors Disclosed herein are compounds of Formula I as disclosed herein, methods of modulating the activity of an estrogen receptor and methods of treating a disorder associated with estrogen receptors. ... | 01/24/2012 |
| 8063099 | Trans-3-aza-bicyclo[3.1.0]hexane derivatives The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicam... | 11/22/2011 |
| 8003684 | Crystal form and pharmaceutical compositions of (+)-R-zileuton Crystalline forms of (+)-R-zileuton, which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of (+)-R-zileuton are characterized by a variety of properties and physical measurements. As well, methods of producing crystall... | 08/23/2011 |
| 7999001 | Antiviral compounds and methods of using thereof Disclosed herein are compounds which exhibit antiviral activity against a plurality of viruses belonging to different families such as Bornaviridae, Filoviridae, Paramyxoviridae, Rhabdoviridae, Arenaviridae, Bunyaviridae, Orthomyxoviridae, and Poxviridae. Thus, meth... | 08/16/2011 |
| 7985768 | Compounds as cannabinoid receptor ligands The present invention relates to thiophene containing compounds of formula (I) wherein R1, R2, R3, and n are as defined in the specification, pharmaceutical compositions comprising such comp... | 07/26/2011 |
| 7981924 | Thiophene derivatives The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents. ... | 07/19/2011 |
| 7973074 | π-conjugated mono-, oligo- and polymeric compounds, and photovoltaic cells comprising them Monomeric, oligomeric or polymeric compound corresponding to the following formula (I): in which: A represents an optionally substituted polycyclic group, the said polycyclic group ... | 07/05/2011 |
| 7964632 | Methods of treatment using a prodrug of an excitatory amino acid This invention relates to synthetic excitatory amino acid prodrugs and processes for their preparation. The invention further relates to methods of using, and pharmaceutical compositions comprising, the compounds for the treatment of neurological disorders and psych... | 06/21/2011 |
| 7935725 | Aryl-substituted bridged or fused diamines as modulators of leukotriene Ahydrolase Aryl-substituted bridged or fused diamine compounds, pharmaceutical compositions containing them, and methods of using the compounds and the pharmaceutical compositions for leukotriene A4 hydrolase (LTA4H or LTA4H) modulation and for the treatm... | 05/03/2011 |
| 7935724 | Thiophene and benzothiophene hydroxamic acid derivatives The present invention relates to a novel class of hydroxamic acid derivatives having a benzothiophene or thiophene backbone. The hydroxamic acid compounds can be used to treat cancer. The hydroxamic acid compounds can also inhibit historic deacetylase and are suitab... | 05/03/2011 |
| RE42327 | Medicinal compositions improving brain function and method for improving brain function An alkyl ether derivative represented by the formula: wherein R1, R2, R3, R4, m and n are as defined in the specification, or salts thereof exhibits synergistically improved anti-... | 05/03/2011 |
| 7888387 | Electro-optic chromophore having an edot structure, and related methods and apparatuses In various embodiments, chromophores are described that include novel election acceptors, novel electron donors, and/or novel conjugated bridges that are useful in nonlinear optical applications. In some embodiments, the present invention provides chromophore archit... | 02/15/2011 |
| 7868038 | Compounds as cannabinoid receptor ligands The present invention relates to thiophene containing compounds of formula (I) wherein m, n, p, q, r, s, R1, R2, and R3 are as defined in the description. Included also are pharmaceutical co... | 01/11/2011 |
| 7855226 | Treatment of inflammatory bowel disease Disclosed herein is a method comprising administering a compound to a mammal suffering from an inflammatory bowel disease for the treatment of said disease, said compound having a structure according to Formula I wherein X,... | 12/21/2010 |
| 7846964 | Thiophene derivatives as spingosine-1-phosphate-1 receptor agonists The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents. ... | 12/07/2010 |
| 7834053 | Medicinal compositions improving brain function and method for improving brain function An alkyl ether derivative represented by the formula: wherein R1, R2, R3, R4, m and n are as defined in the specification, or salts thereof exhibits synergistically improved anti-... | 11/16/2010 |
| 7750040 | Thiophene derivatives The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents. ... | 07/06/2010 |
| 7737176 | Substituted arylhexadienoic acids and esters thereof which can be used for the treatment and prevention of diabetes, dyslipidaemia and atherosclerosis, pharmaceutical compositions comprising them and processes for the preparation of them The invention relates to compounds of the formula I: and to the pharmaceutically acceptable salts thereof, to processes for the preparation of them and to pharmaceutical compositions comprising them, which are useful especi... | 06/15/2010 |
| 7732483 | DNA-PK inhibitors A compound of formula I: and isomers, salts, solvates, chemically protected forms, and prodrugs thereof, wherein: R1 and R2 are independently selected from hydrogen, an optionally substituted C1-7... | 06/08/2010 |
| 7723378 | Hydrogenated benzo (C) thiophene derivatives as immunomodulators The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds particularly as immunosuppressant agents. ... | 05/25/2010 |
| 7674822 | PTP1b inhibitors This invention relates to modulating (e.g., inhibiting) protein tyrosine phosphatase 1B (PTP1B). ... | 03/09/2010 |
| 7671082 | Prodrugs of excitatory amino acids This invention relates to synthetic excitatory amino acid prodrugs and processes for their preparation. The invention further relates to methods of using, and pharmaceutical compositions comprising, the compounds for the treatment of neurological disorders and psych... | 03/02/2010 |
| 7671081 | Multifunctional cationic photoinitiators, their preparation and use Compounds of formula (I): wherein the substituents are as defined herein. ... | 03/02/2010 |
| 7652063 | 10-hydroxy-11-dihydroprostaglandin analogs as selective EP4 agonists A compound comprising or a pharmaceutically acceptable salt or a prodrug thereof, wherein the dashed line represents the presence or absence of a double bond; J is C═O or CHOH; ... | 01/26/2010 |
| 7645791 | Salicylic anilides Novel salicylic anilides are chemical uncouplers useful e.g. for the treatment of obesity. ... | 01/12/2010 |
| 7585888 | Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders This invention relates to novel benzofuran and benzothiophene derivatives of the general formula and their use for the treatment of hyper-proliferative disorders. ... | 09/08/2009 |
| 7582673 | Bissulfonamide compounds as agonists of GalR1, compositions, and methods of use Embodiments of the present invention provide bissulfonamide compounds that are agonists of GalR1. The present invention further provides compositions comprising bissulfonamide compounds that are agonists of GalR1, and methods of use of such compounds and composition... | 09/01/2009 |
| 7576122 | Ophthalmic compositions for treating ocular hypertension This invention relates to potent potassium channel blocker compounds of Formula I or a formulation thereof for the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the us... | 08/18/2009 |
| 7473704 | Cyclohexyl prostaglandin analogs as EP-receptor agonists The invention relates to the use of novel cyclohexyl analogues of E-type prostaglandins as EP4 agonists, in general, and, in particular as ocular hypotensives. The cyclohexyl analogues used in accordance with the invention are represented by the following... | 01/06/2009 |
| 7465752 | Pentenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof Compounds of the formula (I): in which R, R1, R2 and R3 are as defined in the description, to their use for the treatment of dyslipidaemia, atherosclerosis and diabe... | 12/16/2008 |
| 7449490 | Pharmaceutically active compounds and methods of use New fused thiophene compounds are provided and methods of using those compounds for a variety of therapeutic indications. Compounds of the invention are particularly useful for treatment of neuropathic pain. ... | 11/11/2008 |
| 7442808 | Antidiabetic bicyclic compounds Tricyclic compounds containing a cyclopropyl carboxylic acid or carboxylic acid derivative (e.g. amide) fused to a bicyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled receptor 40 (GPR40) and are useful a... | 10/28/2008 |
| 7439271 | Reduction of hair growth Mammalian hair growth is reduced by applying an inhibitor of telomerase to the skin. ... | 10/21/2008 |
| 7435834 | 2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof The present invention relates to compounds of 2-thia-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition... | 10/14/2008 |