Bizarre Patents
User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
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| Number | Title | Issue Date |
| 7973073 | Antidiabetic agent for control of diabetic hyperglycemia and diabetic complications Described herein is a compound of Formula I, which is the metformin salt of the naturally occurring endogenous biological compound, (R)-(+) α lipoic acid, pharmaceutical compositions containing the compound of Formula I, and methods of treatment of diabetes or diab... | 07/05/2011 |
| 7838549 | Linker compound, ligand conjugate, and production methods thereof The present invention provides a novel linker compound which minimizes any nonspecific hydrophobic interactions and is capable of easily adjusting the length to a disulfide group subjected to metal bond to thereby enable effective formation of a metal-sulfur bond; n... | 11/23/2010 |
| 7452914 | Spiro-benzo[c]chromene derivatives useful as modulators of the estrogen receptors The present invention is directed to novel spiro-benzo[C]chromene derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders mediated by one or more estrogen receptors. The compounds of the invention are useful in the treatm... | 11/18/2008 |
| 7429614 | Medicament containing an effector of the glutathione metabolism together with α-lipoic acid for treating diabetes mellitus The invention relates to a medicament containing an effector of the glutathione metabolism together with α-lipoic acid for treating diabetes mellitus. This medicament enables disturbances of the thiol-disulfide status or those that occur, for example, in diabetes m... | 09/30/2008 |
| 7399755 | Formulations comprising multiple dietary and endogenously made antioxidants and B-vitamins and use of same The invention is directed to formulations comprised of multiple dietary and endogenously made antioxidants and B-vitamins and the use of these formulations in preventing and treating coronary artery disease. ... | 07/15/2008 |
| 7335384 | Nutrient compositions for the treatment and prevention of inflammation and disorders associated therewith The present disclosure describes a novel composition for the treatment and/or prevention of neurogenic inflammation. Such composition is also useful in the treatment and/or prevention of disease states and conditions associated with neurogenic inflammation. Such dis... | 02/26/2008 |
| 7326690 | Modulation of cell fates and activities by phthalazinediones Phthalazinediones that function as intracellular redox modulators are useful in treating cells in various disease states where intracellular redox status is impaired. By buffering aberrant redox states, phthalazinediones enable cellular processes essential for survi... | 02/05/2008 |
| 7309696 | Compositions and methods for targeting cancer cells The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The compositions o... | 12/18/2007 |
| 7304089 | Preparation for improved dietary utilisation Food, feed or drug preparations are described that contain conjugated trans/cis-octadecatrienoic acid, and processes are described for their production. Inventive preparations preferably comprise calendic acid. The invention also relates to the use of the preparatio... | 12/04/2007 |
| 7294620 | Lipid analogs for inhibiting HIV-1 activity The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294619 | Lipid analogs for inhibiting the activity of hepatitis B antigen The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294621 | Lipid analogs for combating tumors The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7285664 | Heterocyclic or benzenic derivatives of lipoic acid, their preparation and their use as medicaments A compound having a formula selected from the group consisting of wherein the substituents are defined as in the specification. The compounds are useful as intermediates in the preparation of compounds of formula... | 10/23/2007 |
| 7268132 | Substituted thioacetamides The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases. ... | 09/11/2007 |
| 7244703 | Pharmaceutical compositions and methods for peptide treatment Compositions and methods for treating a patient with a pharmaceutically active peptide that combines a pharmaceutically active peptide, a permeation enhancer, and a carrier, are disclosed. ... | 07/17/2007 |
| 7235582 | Basic salt of thioctic acid with L-carnitine Salt of thioctic acid with L-carnitine with the formula: AY(X)x where A is where Y is the cation of an alkaline metal, of an alkaline earth metal or is a quaternary ammonium group,... | 06/26/2007 |
| 7208609 | Method for producing thioctic acid The invention relates to a method for producing pure racemic, R- or S-thioctic acid or mixtures thereof by reacting 6,8-disubstituted octanoic acid or their salts or esters with sulfides, sulfur or sulfites. ... | 04/24/2007 |
| 7202270 | Convenient stable non-hygroscopic crystalline solid forms of racemic and chiral LA-plus salts: process for their manufacture and uses A process for the manufacture of new crystalline salts of N-[2-(dimethylamino)ethyl]-1,2-dithiolane-3-pentanamide (racemic and chiral forms) is described. Such salts are stable, crystalline and have very good solubility in water. The salts exhibit antioxidant proper... | 04/10/2007 |
| 7196065 | Enteral formulation A formulation for enteral administration to a patient is disclosed. ... | 03/27/2007 |
| 7189748 | Compounds and methods for treating insulin resistance and cardiomyopathy Novel compounds, compositions comprising compounds, and methods for methods for preparing and using compounds are described herein. Methods of treating or ameliorating various conditions, including insulin resistance, pancreatic beta cell apoptosis, obesity, pro-thr... | 03/13/2007 |
| 7141557 | Lipid analogs for treating viral infections A method of treating viral infections, and in particular HIV-1, hepatitis B virus, and herpes virus, is disclosed. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative.... | 11/28/2006 |
| 7125882 | Treatment of acne using alkonolamine compositions Acne is treated or prevented by the topical application of compositions containing an alkanolamine such as dimethylaminoethanol, tyrosine, and a sulfur ingredient such as lipoic acid or glutathione. Adjunct ingredients such as fatty acid esters of ascorbic acid, e.g... | 10/24/2006 |
| 7118762 | Controlled release lipoic acid A controlled release formulation of lipoic acid is disclosed. The lipoic acid is combined with excipient materials in such a way that those materials provide for gradual release of the lipoic acid in a manner which makes it possible to substantially increase the per... | 10/10/2006 |
| 7112561 | Pharmaceutical compositions and methods for insulin treatment Compositions and methods for treating a patient with insulin that combines insulin, a permeation enhancer, and a carrier that maintains an acidic pH, are disclosed. ... | 09/26/2006 |
| 7109362 | Process for the preparation of lipoic acid and dihydrolipoic acid The present invention relates to a process for the preparation of R- and S-lipoic acid and R- and S-dihydrolipoic acid comprising (a) reaction of where MS is SO | 09/19/2006 |
| 7081479 | Treatment of acne using alkonolamine compositions Acne is treated or prevented by the topical application of compositions containing an alkanolamine such as dimethylaminoethanol, tyrosine, and a sulfur ingredient such as lipoic acid or glutathione. Adjunct ingredients such as fatty acid esters of ascorbic acid, e.g... | 07/25/2006 |
| 7078402 | Aminothiol ester compounds, pharmaceutical and cosmetics compositions containing same and uses thereof The invention relates to novel aminothiol ester compounds having the general formula (I): and to a method for preparing them and to their use in pharmaceutical compositions intended for use in human or veterinary... | 07/18/2006 |
| 7074832 | Compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use Topical compositions which include urea and an antimicrobial agent, particularly sulfacetamide or metronidazole, are described. Sulfacetamide compositions further including sulfur are also described. Methods for treating dermatological disorders using the compositio... | 07/11/2006 |
| 7049461 | Treatment of leukemia A preferred embodiment of the invention encompasses a compounds having the property of anti-carcinogenic activity against human leukemia comprising the use of 4-(4-Ethoxy-phenyl)-2-(N′-fluoren-9-ylidene-hydrazino)-2-hydroxy-4-oxo-butyric acid methyl ester (OF-13),... | 05/23/2006 |
| 7030251 | Modifications of the trometamol salt of R-thioctic acid as well as a process for their production The invention relates to new modifications of the trometamol salt of R-thioctic acid of the formula I, processes for their production, pharmaceutical preparations containing these modifications, and their medical applic... | 04/18/2006 |
| 7030154 | Stability of lipoic acid A method of stabilizing R-α-lipoic acid includes combining R-α-lipoic acid with nicotinamide in a weight ratio between about 10:4 to about 10:8. A composition for treating oxidative stress includes R-α-lipoic acid and nicotinamide in a weight ratio of between abo... | 04/18/2006 |
| 7026469 | Compositions and methods of double-targeting virus infections and cancer cells The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The compositions o... | 04/11/2006 |
| 6998407 | Antagonists of MCP-1 function and methods of use thereof Chemical compounds which are antagonists of Monocyte Chemoattractant Protein-1 (MCP-1) function, pharmaceutical compositions comprising these compounds, methods of treatment employing these compounds and compositions, and processes for preparing these compounds. The... | 02/14/2006 |
| 6998419 | 3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same Disclosed are 3,4,5-trisubstituted aryl nitrone compoundsd and pharmaceutical compositions containing such compounds. The 3,4,5-trisubstituted aryl nitrone compounds have formula (I); where R1–R4 are as defined in the specification. The discl... | 02/14/2006 |
| 6979459 | Treatment of skin damage using polyenylphosphatidycholine Polyenylphosphatidylcholine is topically applied to treat skin damage, such as contact dermatitis (particularly diaper area dermatitis), atopic dermatitis, xerosis, eczema (including severe hand and foot eczema), rosacea, seborrhea, psoriasis, thermal and radiation ... | 12/27/2005 |
| 6964969 | Composition and method for treating impaired or deteriorating neurological function A nutritional supplement composition for normalizing impaired or deteriorating neurological function in humans is composed of: at least one agent which promotes synthesis of ATP and/or creatine phosphate in the body, at least one antioxidant for scavenging free radi... | 11/15/2005 |
| 6951887 | Lipoic acid derivatives and their use in treatment of disease This invention relates to the identification of a novel class of therapeutic agents which selectively target and kill tumor cells and certain other types of diseased cells, and to compositions comprising lipoic acid derivatives which poison the pyruvate dehydrogenas... | 10/04/2005 |
| 6932963 | Treatment of skin wounds using polyenylphosphatidylcholine and alkanolamines Polyenylphosphatidylcholine in combination with an alkanolamine are topically applied to treat skin wounds, promote healing, and minmize scar formation. Typical compositions contain from about 0.25% to about 12% of a polyenylphosphatidylcholine preparation obtained ... | 08/23/2005 |
| 6923960 | Antioxidant combination composition and use thereof An orally or parenterally administrable composition which comprises the following components: (a) L-carnitine inner salt or a pharmacologically acceptable salt thereof; (b) acetyl L-carnitine inner salt or a pharmacologically acceptable sal... | 08/02/2005 |
| 6914071 | Antioxidant containing composition and method A companion pet diet meeting ordinary nutritional requirements of the pet and further comprising a sufficient amount of an antioxidant or mixture thereof to inhibit the onset of deterioration of the mental capacity of said companion pet in its aged years. ... | 07/05/2005 |
