Bizarre Patents
Apparatus for Simulating a High Five
A self-righting hand-arm configuration which is adapted to pivot when struck by a user, thereby simulating a "high five."
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8399505 | Sulfonylpyrroles Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors. ... | 03/19/2013 |
| 8383668 | 11-beta-hydroxysteroid dehydrogenase type 1 active compounds The use of substituted amides for modulating the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) and the use of these compounds as pharmaceutical compositions, are described. Also a novel class of substituted amides, of the general formula I. Their u... | 02/26/2013 |
| 8329741 | Substituted pyrrolidine compounds with central nervous system activity Provided herein are substituted pyrrolidines that demonstrate binding at biogenic amine transporters and can be synthesized by a methodology based on a chiral dirhodium catalyst. Compositions comprising substituted pyrrolidines can be used to treat central nervous s... | 12/11/2012 |
| 8268881 | Carboxamide derivatives as muscarinic receptor antagonists The invention relates to compounds of formula processes and intermediates for their preparation, their use as muscarinic antagonists and pharmaceutical composition containing them. ... | 09/18/2012 |
| 8263638 | Dosing regimens for ion channel modulating compounds Dosing regimens, routes of administration and methods for the treatment or prevention of arrhythmias are disclosed. In these methods, arrythmias (e.g. atrial fibrillation, atrial flutter, early after depolarizations and prolongation of QT interval) may be reduced or... | 09/11/2012 |
| 8227505 | Method for preparing enantiomerically pure 4-pyrrolidino phenylbenzyl ether derivatives The invention relates to a method for preparing enantiomerically pure 4-pyrrolidinophenylbenzyl ether derivatives of formula I: wherein R1, R21, R22, R23, R24 and n are... | 07/24/2012 |
| 8211936 | Co-crystals of pyrrolidinones The present invention relates to new co-crystals of pyrrolidinones having the formula (I) wherein R1 is a C1-C6 alkyl group. R2 is a C1-C6 alkyl group which is optionally substituted by 1 to 3 halogen... | 07/03/2012 |
| 8207219 | Ion channel modulating activity I Methods, compositions, dosing regimes, and routes of administration for the treatment or prevention of arrhythmias. In these methods, early afterdepolarizations and prolongation of QT interval may be reduced or eliminated by administering ion channel modulating comp... | 06/26/2012 |
| 8207218 | DMAE as sole agent for the treatment of mild cognitive impairment The present invention relates to the use, as sole active ingredient, of dimethylaminoethanol (DMAE) in free form or in the form of salts or of esters and also of hydrates and solvates thereof, for the manufacture of a medicament for use in the treatment of a non-dem... | 06/26/2012 |
| 8188140 | Uses of ion channel modulating compounds Methods, formulations, dosing regimes, and routes of administration for the treatment or prevention of arrhythmias, including the treatment or prevention of atrial fibrillation. In these methods, the disease or condition is treated or prevented by administering one ... | 05/29/2012 |
| 8178576 | Non-polymeric lipophilic pharmaceutical implant compositions for intraocular use Solid or semi-solid intraocular implant compositions are disclosed. The compositions contain a lipophilic compound but lack a polymeric ingredient. ... | 05/15/2012 |
| 8097647 | Augmented cognitive training The present invention provides methods of treating cognitive deficits associated with mental retardation. The methods comprise combining cognitive training protocols and a general administration of phosphodiesterase 4 inhibitors. ... | 01/17/2012 |
| 8071639 | Soft anticholinergic zwitterions Soft anticholinergic zwitterions of the formulas: wherein R1 and R2 are both phenyl or one of R1 and R2 is phenyl and the other is cyclopentyl; and wherein each asterisk marks a c... | 12/06/2011 |
| 8067458 | Alkoxyalkyl-substituted cyclic ketoenols The invention relates to new alkoxyalkyl-substituted cyclic ketoenols of the formula (I) in which A, B, D, G, W, X and Y have the definitions indicated above, to processes and intermediates for the... | 11/29/2011 |
| 8058304 | Merged ion channel modulating compounds and uses thereof Merged compounds of ion channel modulating compounds, including, for example, merged compounds of the ion channel modulating compound of the following formula: (I) are described herein, as well as methods of making and using such merged compounds and pharmaceutical ... | 11/15/2011 |
| 8058305 | Pyrrolidine derivatives as prostaglandin modulators Substituted pyrrolidine compounds are provided, and methods of treatment and pharmaceutical composition that utilize or comprise one or more such compounds. Compounds of the invention are useful for a variety of therapies, including treating or preventing preterm la... | 11/15/2011 |
| 8048908 | 11β-hydroxysteroid dehydrogenase type 1 active compounds The use of substituted amides for modulating the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) and the use of these compounds as pharmaceutical compositions, are described. Also a novel class of substituted amides, of the general formula I. Their u... | 11/01/2011 |
| 8026273 | 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient An 8-azaprostaglandin represented by formula (I) (wherein all symbols have the same meanings as described in the specification), a pharmaceutically acceptable salt thereof or a cyclodextrin clathrate thereof. Since the comp... | 09/27/2011 |
| 8022098 | Deuterated aminocyclohexyl ether compounds and processes for preparing same This invention is directed to deuterated aminocyclohexyl ether compounds and processes for preparing same and methods of using same. ... | 09/20/2011 |
| 8013008 | Cyclic amine compound A compound represented by the formula (I) each symbol of which is defined in the specification, or a salt thereof which has a superior androgen receptor regulating activity. ... | 09/06/2011 |
| 8008342 | Ion channel modulating compounds and uses thereof Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatme... | 08/30/2011 |
| 8008341 | Pharmaceutically active benzsulfonamide derivatives as inhibitors of protein junkinases The present invention relates to benzsulfonamide derivatives of formula I and methods of use thereof. The benzsulfonamide derivatives of the present invention are efficient modulators of the JNK pathway. In particular the benzsulfonamide derivatives of the present i... | 08/30/2011 |
| 7998999 | Cyclohexyl substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 The present invention discloses novel compounds of Formula I: having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, a... | 08/16/2011 |
| 7985766 | Combination of anticholineric and β mimetics for the treatment of respiratory diseases The present invention describes a combination of an anticholinergic, such as R,R-glycopyrrolate, and a β mimetic, such as tormoterol, for the treatment of respiratory diseases including airway inflammation or obstruction such as chronic obstructive pulmonary diseas... | 07/26/2011 |
| 7981923 | Tetralin and indane derivatives and uses thereof Compounds of the formula I, II or III: or pharmaceutically acceptable salts thereof, wherein m, n, q, Ar, R1, R2, R3, R4 and R5 are as defined herein. Also pr... | 07/19/2011 |
| 7977373 | Prodrugs of ion channel modulating compounds and uses thereof Prodrugs of ion channeling modulating compounds, including, for example, prodrugs of the ion channel modulating compound of the following formula: are described herein, as well as methods of making and using such prodrugs and pharmaceutical compositions containing s... | 07/12/2011 |
| 7968592 | 3-aminopyrrolidone derivatives 3-aminopyrrolidone compounds and pharmaceutically acceptable salts thereof that are active as sodium and/or calcium channel modulators and therefore useful in preventing, alleviating and curing a wide range of pathologies, including, but not limited to cardiovascula... | 06/28/2011 |
| 7960429 | Kappa-opiate agonists for the treatment of diarrhea-predominant irritable bowel syndrome The present invention concerns methods useful in treating a subject having diarrhea-predominant IBS (IBS-D) by administering N methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidin-1-yl)ethyl]-2,2-diphenylacetamide and/or a pharmaceutically acceptable salt thereof to ... | 06/14/2011 |
| 7947731 | Augmented cognitive training The present invention provides methods of therapy of cognitive deficits associated with a central nervous system disorder or condition, methods of enhancing cognitive performance and methods for repeated stimulation of neuronal activity or a pattern of neuronal acti... | 05/24/2011 |
| 7919520 | Inhibitors of tace The present invention relates to compounds that inhibit TACE, compositions thereof, and methods of using those compounds and compositions for treating diseases. ... | 04/05/2011 |
| 7915303 | Glycopyrronium salts and their therapeutic use A glycopyrronium salt such as glycopyrronium iodide has a lower glass transition temperature than glycopyrronium bromide. It is therefore more suitable for formulation. ... | 03/29/2011 |
| 7863317 | Lactams of alkylated acyclic diamine derivatives as modulators of chemokine receptor activity The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma, multiple sclerosis, artherosclerosis, and rheumatoid arthritis. | 01/04/2011 |
| 7820712 | Uses of ion channel modulating compounds Methods, formulations, dosing regimes, and routes of administration for the treatment or prevention of arrhythmias, including the treatment or prevention of atrial fibrillation. In these methods, the disease or condition is treated or prevented by administering one ... | 10/26/2010 |
| 7816396 | Method for increasing the bioavailability of glycopyrrolate The invention relates to a method of treating sialorrhea in a human patient, which comprises orally administering glycopyrrolate in a liquid solution to the human patient under fasted conditions. ... | 10/19/2010 |
| 7816395 | Pyrrolidinone anilines as progesterone receptor modulators The present invention relates to a compound represented by the following formula: or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a combination thereof, wherein R1, R2, and X ar... | 10/19/2010 |
| 7799823 | Androgen modulators The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth. ... | 09/21/2010 |
| 7754758 | Pyrrolidine derivatives acting as CCR3-receptor antagonists Compounds of formula I in free or salt form, wherein T, X, Y, U, R1, R2, m, n and p have the meanings as indicated in the specification, are useful for treating conditions mediated by CCR3. Pharmaceuti... | 07/13/2010 |
| 7732481 | Prolinylarylacetamides Novel compounds of the formula (I), in which R, R1, R2, R3, X, X′ and Y have the meaning indicated in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboe... | 06/08/2010 |
| 7705036 | Deuterated aminocyclohexyl ether compounds and processes for preparing same This invention is directed to deuterated aminocyclohexyl ether compounds and processes for preparing same and methods of using same. ... | 04/27/2010 |
| 7696243 | Pyrrolidin-2-one derivatives for use as DPreceptor agonists The present invention is directed to compounds that may be used as agonists of prostaglandin receptors. More specifically, the specification describes methods and compositions for making and using DP1 receptor agonists that are pyrrolidin-2-one derivatives. ... | 04/13/2010 |
