Did You Know...
...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 8168598 | Optimised formulation of tobramycin for aerosolization The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatmen... | 05/01/2012 |
| 8101582 | Topical ophthalmic compositions containing tobramycin and dexamethasone Ophthalmic pharmaceutical compositions containing tobramycin, dexamethasone and deacetylated xanthan gum are described. The compositions provide longer ocular retention for enhanced ocular bioavailability of tobramycin and dexamethasone. In a preferred embodiment, t... | 01/24/2012 |
| 7939502 | Optimised formulation of tobramycin for aerosolization The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatmen... | 05/10/2011 |
| 7829544 | Aqueous solution preparation containing aminoglycoside antibiotic and bromfenac Stable and clear aqueous solution preparations comprising an aminoglycoside antibiotic or a pharmacologically acceptable salt thereof and bromfenac being a nonsteroidal antiinflammatory agent or a pharmacologically acceptable salt thereof. ... | 11/09/2010 |
| 7696178 | Optimised formulation of tobramycin for aerosolization The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatmen... | 04/13/2010 |
| 7345024 | Pharmaceutical preparation, method for its production as well as its use The invention relates to hardly soluble antiphlogistic salts and antiphlogistic-antibiotic pharmaceutical preparations and their use. The hardly water soluble antiphlogistic antibiotics salts have as their cationic component one of the antibiotics gentamicin, clinda... | 03/18/2008 |
| 7267815 | Methods and reagents for the enhancement of virus transduction in the bladder epithelium Agents and methods for enhancing recombinant virus transduction in the bladder epithelium are described. A first method involves contacting the luminal surface of the bladder with a composition comprising a transduction enhancing agent and an oncolytic virus. Altern... | 09/11/2007 |
| 7238380 | Water containing soluble fiber A water-like fluid containing safe water and a significant quantity of soluble dietary fiber. The resulting solution is generally optically clear and has physical properties similar to potable water. The fluid is intended as a replacement for bottled, or other water... | 07/03/2007 |
| 7235370 | Site-specific aminoglycoside derivatives for use in immunodiagnostic assays A method of making a derivatized aminoglycoside includes reacting an aminoglycoside with at least 2 equivalents of a divalent metal ion in an aprotic solvent to complex two neighboring amino group and hydroxyl group pairs; reacting the non-complexed amino groups wit... | 06/26/2007 |
| 6987094 | Optimized formulation of tobramycin for aerosolization The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatmen... | 01/17/2006 |
| 6818625 | Method for increasing survival rate of cells in animal cell culture under hypoxia condition The present invention relates to a method for increasing survival rate of cells in animal cell culture under hypoxia condition by adding antibiotics to the culture media. The method of present invention comprises a step of culturing animal cells in culture media con... | 11/16/2004 |
| 6716822 | Therapeutic agent for ischemia which inhibits apoptosis under ischemic condition The present invention relates to a therapeutic agent for ischemia which inhibits apoptosis under ischemic condition. The therapeutic agent of the present invention comprises antibacterial agents of quinolones, quinones, aminoglycosides or chloramphenicol as an activ... | 04/06/2004 |
| 6541456 | Antimicrobial 2-deoxystreptamine compounds The present invention is directed to analogs of aminoglycoside compounds of the class having a glycosylated 2-deoxystreptamine (2-DOS) ring as well as their preparation and use as prophylactic or therapeutics against microbial infection. Compounds of the ... | 04/01/2003 |
| 6475993 | Treatment of hereditary diseases with gentamicin This invention relates to a method of treating an inherited disease due to a point mutation producing a stop codon by administering an effective dose of an aminoglycoside antibiotic or a derivative thereof. Mdx mouse, which is an animal model for Duchenne... | 11/05/2002 |
| 6344473 | Imidazoles useful as nitric oxide synthase inhibitors 1,3-diazolino and 1,3-diazolidino heterocycle derivatives useful as nitric oxide synthase inhibitors.... | 02/05/2002 |
| 6248390 | Fiber-water--water containing soluble fiber A shelf stable, ready to use, essentially tasteless and odorless water-like fluid for humans/animals comprised of safe water and a significant quantity of one or more water-soluble dietary fibers. Fiber-water is intended to be consumed by drinking or by e... | 06/19/2001 |
| 5929039 | Method for treating cardiac dysfunction and pharmaceutical compositions useful therefor The present invention relates generally to a method for, and pharmaceutical compositions useful in, the prophylaxis and/or treatment of cardiac dysfunction in a mammal by the administration of an effective amount of an agent capable of blocking or inhibit... | 07/27/1999 |
| 5900406 | Use of antibiotics of the type 2-deoxystreptamine substituted with aminosugars to inhibit growth of microorganisms containing group I introns The invention described herein provides for methods of screening for compounds that can be used to prevent or inhibit the growth of microbial eukaryotes, particularly plant or animal pathogens. The screening methods of the invention involve the step of sc... | 05/04/1999 |
| 5814488 | Semisynthetic 1-N-ethylgentamicin C1a and method for its preparation This invention relates to the fields of microbiology and antibiotics. Particularly, it relates to a new mutant strain, a method of its mutation breeding, to a monocomponent Gentamicin C1a produced by this strain which is used as mother nucleus ... | 09/29/1998 |
| 5731007 | Pharmaceutical composition for skin diseases The present invention relates to novel pharmaceutical composition for skin diseases, in particular to novel pharmaceutical composition useful for treatment of skin diseases; e.g. burns, wounds, general operative wounds, pernio, decubitus, folliculitis, im... | 03/24/1998 |
| 5714469 | Method of treating sepsis The invention relates to the method of preventing and treating sepsis using (S)-5-oxo-L-prolyl-L--glutamyl-L--aspartyl-N8 -(5-amino-1-carboxypentyl)-8-oxo-N7 -N-N-(5-oxo-L-prolyl)-L--glutamyl!-L--aspar... | 02/03/1998 |
| 5677288 | Use of aminoglycosides to protect against excitotoxic neuron damage A method is disclosed for reducing excitotoxic damage to neurons, which can occur as a result of stroke, cardiac arrest, or other events or conditions. This method involves administering an aminoglycoside that suppresses the flow of calcium ions into neur... | 10/14/1997 |
| 5663152 | Potentiators for aminoglycosides The present invention provides antimicrobial compositions, especially compositions comprising an antimicrobial (microbiocidal or microbiostatic) compound and a potentiator of antimicrobial activity. Compositions of the invention combinating an antimicrobi... | 09/02/1997 |
| 5662929 | Therapeutic liposomal formulation The invention relates to a liposomal formulation containing a therapeutic agent. The formulation of the invention when administered to animals, allows a substantial increase in antibacterial activity of the agent, through an enhanced penetration of the ag... | 09/02/1997 |
| 5604208 | Antibiotic preparation and use of the same in plants An antibiotic formulation comprising gentamicin, and optionally tetracycline or oxytetracycline, for use in plants.... | 02/18/1997 |
| 5595977 | Salts of amino glycosides The present invention relates to novel amino glycoside salts of sucrose-octa-O-sulfonic acid of formula I: ([sucrose-octa-O-sulfonic acid8- ]-[R-(NH3+)x ]y -Mzn+) ... | 01/21/1997 |
| 5534408 | 2-deoxystreptamine aminoglycoside inhibition of HIV RRE/Rev binding Disclosed is a method for the inhibition of binding of a ligand to an RNA, the inhibition being mediated by a small organic molecule which binds to the RNA, thereby inhibiting ligand binding. A preferred class of small organic molecules are the 2-deoxystr... | 07/09/1996 |
| 5527781 | 4-O-(aminoglycosyl)- or 4,6-di-O-(aminoglycosyl)-2,5-dideoxy-5,5-difluorostreptamine derivatives As new compounds are now synthetized 5-deoxy-5,5-difluoro derivatives of aminoglycosidic antibiotics of neamine, kanamycin A-series, kanamycin B-series, gentamicin-series and seldomycin-series. Further, the 1-N-(-hydroxy-ω-aminoalkanoyl) derivativ... | 06/18/1996 |
| 5149694 | Combination of tobramycin and dexamethasone for topical ophthalmic use Disclosed are pharmaceutical compositions comprising tobramycin and dexamethasone for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for infection and control of inflammatory response for opt... | 09/22/1992 |
| 5149693 | Combination of tobramycin and fluorometholone for topical ophthalmic use Disclosed are pharmaceutical compositions comprising tobramycin and fluorometholone or fluorometholone acetate for topical ophthalmic delivery and methods of treatment comprising administering said composition when indicated for infection and control of i... | 09/22/1992 |
| 5079234 | Inhibitors of aminoglycoside nephrotoxicity Certain water-soluble polyanionic organic acid polymers in the weight range of from about 1,000 to 30,000 daltons may be use to inhibit aminoglycoside nephrotoxicity. These polyanionic polymers are homopolymers or copolymers comprised of monomers selected... | 01/07/1992 |
| 5061729 | Pharmaceutical composition and process for preparing the same The invention relates to pharmaceutical compositions as well as the preparation thereof which are useful for improving the status of patients suffering from external otitis or otitis (otitis media), or particularly from a chronic otitis (otitis media chro... | 10/29/1991 |
| 4932994 | Evaporation inhibitors An evaporation inhibitor, having particular use with spray mixtures of agricultural chemicals applied by the low-volume method, in the form of a paraffin-containing aqueous dispersion or a self-emulsifying solution in an organic solvent, and having the fo... | 06/12/1990 |
| 4888327 | Topical antibiotic compositions Disclosed are antibiotic compositions for topical administration comprising an aminoglycoside, a benzylpyrimidine and a sulfonamide.... | 12/19/1989 |
| 4886781 | Substituted 2,3-diphenyl-1,2-dihydroquinoxalines and antibiotics for growths promoting Novel substituted 2,3-diphenyl-1,2-dihydroquinoxalines are useful for promoting growth and improving feed conversion efficiencies in meat-producing animals. In addition, the novel compounds are useful for controlling coccidiosis in poultry.... | 12/12/1989 |
| 4855287 | Aminoglycoside compounds, processes for production thereof, and pharamaceutical composition containing the same An aminoglycoside compound represented by the following formula (I) ##STR1## wherein one of R1 and R2 represents a hydrogen atom, and the other represents a methyl group, R3 represents a hydrogen atom or a hydroxyl group, ... | 08/08/1989 |
| 4831015 | High potency biomass-free avoparcin and a method for its preparation The invention relates to high potency biomass-free avoparcin and a method for its preparation.... | 05/16/1989 |
| 4803209 | Substituted 2,3-diphenyl-1,2-dihydroquinoxalines Novel substituted 2,3-diphenyl-1,2-dihydroquinoxalines are useful for promoting growth and improving feed conversion efficiencies in meat-producing animals. In addition, the novel compounds are useful for controlling coccidiosis in poultry.... | 02/07/1989 |
| 4749694 | Novel lysine esters used as absorption Novel lysine esters used as absorption enhancing agents for gastrointestinally and rectally administered drugs. Also provided are processes for preparation of said lysine ester compounds as well as pharmaceutical formulations and methods for their use as ... | 06/07/1988 |
| 4656160 | Aminoglycoside derivatives Aminoglycoside derivatives and pharmaceutically acceptable salts thereof which are useful as prophylactic and therapeutic agents for infectious diseases caused by pathogenic microorganisms, and a pharmaceutical composition comprising the same.... | 04/07/1987 |
