User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8138211 | Isothiazolyloxyphenylamidines and their use as fungicides The present invention relates to isothiazolyloxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms, and also to a composition for this purpose w... | 03/20/2012 |
| 8138212 | Synergistic microbicidal compositions This invention relates to synergistic combinations of selected isothiazolin-3-one microbicides in combination with a second microbicide or formulation ingredient or raw material. The combinations have greater efficacy than would be expected from combinations of the ... | 03/20/2012 |
| 8119670 | Antimicrobial composition useful for preserving wood Antimicrobial compositions useful for preserving wood, and comprising a variety of antimicrobial compounds. ... | 02/21/2012 |
| 8093277 | Antimicrobial composition useful for preserving wood Antimicrobial compositions useful for preserving wood, and comprising a variety of antimicrobial compounds. ... | 01/10/2012 |
| 8088807 | Microbicidal composition A microbicidal composition comprising relatively high levels of a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one; a metal nitrate; and water. The composition optionally contains magnesium chloride. ... | 01/03/2012 |
| 8076363 | Isothiazolone-containing preservative with improved effectiveness The invention relates to a preservative which 5 comprises a) one or more isothiazolones and b) one or more glycerol monoalkyl ethers, to the use of the preservatives for microbicidal finishing of cosmetic and pharmaceutical products, and to corresponding microbicida... | 12/13/2011 |
| 8067452 | 3-hydroxyisothiazole-4-carboxamidine derivatives as CHK2 inhibitors This invention provides compounds of Formula I which are inhibitors of Chk2 and are useful as a radiation protection agents in anticancer radiotherapy. A method of modulating Chk2 in vitro includes treating a substrate with Chk2 in the presence of compounds of formu... | 11/29/2011 |
| 8058298 | Antimicrobial composition useful for preserving wood Antimicrobial compositions useful for preserving wood, and comprising a variety of antimicrobial compounds. ... | 11/15/2011 |
| 8058297 | Compounds for the treatment of proliferative disorders The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 ... | 11/15/2011 |
| 7981912 | Indole acetic acids exhibiting CRTH2 receptor antagonism and uses thereof The invention relates to indole acetic acid compounds which function as antagonists of the CRTH2 receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D2 and its metabolites or certain thromboxane metab... | 07/19/2011 |
| 7960419 | Substituted carboxamides This application relates to a substituted carboxamide compound of formula I, or a pharmaceutically acceptable salt thereof, as defined herein, a pharmaceutical composition thereof, and its use in treating pain. ... | 06/14/2011 |
| 7947718 | Isoxazole compounds as histamine Hmodulators Certain isoxazole compounds are histamine H3 modulators useful in the treatment of histamine H3 receptor mediated diseases. ... | 05/24/2011 |
| 7939554 | Protein phosphatase inhibitors A method of inhibiting protein tyrosine phosphatase in a subject includes administering to the subject a therapeutically effective amount of at least one benzo-1,4-quinone, phenyl isothiazolone, or analog thereof to the subject. ... | 05/10/2011 |
| 7897629 | Therapeutic compounds Disclosed herein is a compound having a structure or a pharmaceutically acceptable salt thereof, or a prodrug thereof. Therapeutic methods, compositions, and medicaments related thereto are also disclosed. ... | 03/01/2011 |
| 7872033 | Compounds as cannabinoid receptor ligands The present application relates to isothiazolylidene containing compounds of Formula (I) wherein R1, R2, R3, R4, and L are as defined in the specification, compositions comprising... | 01/18/2011 |
| 7781466 | Preparation for the fungicidal and algicidal finish of alkaline coating compositions The invention relates to a preservative comprising at least one isothiazolone, at least one quaternary ammonium compound, and at least one stabilizer selected from the group of sulphite salts, hydrogen sulphite salts, sulphite-releasing compounds and hydrogen-sulphi... | 08/24/2010 |
| 7772262 | Substituted benzoylguanidines, method for production and use thereof as medicament or diagnostic and medicament comprising the same The present invention relates to substituted benzoylguanidines of the formula I: in which R1 to R8 and X and Y are as described in the specification, and their pharmaceutically acceptable salts are substituted acylguanidine... | 08/10/2010 |
| 7745469 | Fungicidal active substance combinations The invention relates to novel fungicidally active compound combinations of 2′-cyano-3,4-dichloroisothiazole-5-carboxanilide of the formula and active compounds listed in the disclosure. ... | 06/29/2010 |
| 7741351 | Compounds which potentiate glutamate receptor and uses thereof in medicine This case discloses compounds of formula (I) wherein R1 is C1-6alkyl, haloC1-6alkyl, C2-6alkenyl, amino, monoC1-4alkylamino or diC1-4alkylamino; R2 and R3, which may be the same ... | 06/22/2010 |
| 7652047 | Phenylamino isothiazole carboxamidines as MEK inhibitors The invention concerns compounds which inhibit MEK and which have activity as anti-neoplastic agents. These compounds include N-substituted-3-hydroxy-5-arylamino-isothiazole-4-carboxamidines. Also included are the tautomeric isothiazol-3(2H)-ones. ... | 01/26/2010 |
| 7572821 | Compounds for the treatment of proliferative disorders The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 ... | 08/11/2009 |
| 7560476 | Microbicidal composition A microbicidal composition containing: (a) at least one non-halogenated 2-alkyl-4-isothiazolin-3-one selected from substituted and unsubstituted 2-(C1-C4)alkyl-4-isothiazolin-3-ones; and (b) at least one of 2,2′-dithiobis(N-methylbenzamide) a... | 07/14/2009 |
| 7442240 | Alkoxylpropylisothiazolinone and preparation method and use thereof An alkoxylpropyl isothiazolinone of formula: C6H6Cl2NO2SR, in which R is CH3, CH2CH3, CH(CH3)2, CH2CH2CH2CH3, CH2 | 10/28/2008 |
| RE40558 | Therapeutic uses of di-aryl acid derivatives The use of diaryl acid derivatives of formula (I) or pharmaceutically acceptable salts, N-oxides, hydrates or solvates thereof, wherein the variables shown are defined in the disclosure, and their pharmaceutical compositions as P... | 10/28/2008 |
| 7435748 | Gamma-secretase inhibitors Compounds of formula I: inhibit gamma-secretase and hence find use in treatment of Alzheimer's disease. ... | 10/14/2008 |
| 7405218 | Isothiazole derivatives useful as anticancer agents The present invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein X1, R1, R2 and R3 are as defined herein.... | 07/29/2008 |
| 7399765 | Substituted diazabicycloalkane derivatives Compounds of formula (I) Z-Ar1—Ar2 (I) wherein Z is a diazabicyclic amine, Ar1 is a 5- or 6-membered aromatic ring, and Ar2 is selected from the group consisting of an unsubstituted or substitute... | 07/15/2008 |
| 7396846 | Growth hormone secretagogues This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in thes... | 07/08/2008 |
| 7396838 | Use of 1H-indol-3-yl-2-oxoacetamide compounds A method of treating cancer including administering to a subject in need thereof an effective amount of a compound of the formula 1: wherein R1, R2, R3, R4, and n are as defined h... | 07/08/2008 |
| 7384929 | N-aryl azaspiroalkene and azaspiroalkane compounds and methods of preparation and use thereof Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are N-aryl or heteroaryl azaspiroalkene/alkane compounds, prodrugs or metabolites of these compounds, or pharmaceutically acceptab... | 06/10/2008 |
| 7371771 | Alkenyl-substituted spirocyclic sulfamides as inhibitors of gamma-secretase Compounds of formula (I) are disclosed: wherein R4 is an alkenyl group of defined structure. The compounds inhibit gamma-secretase, and hence are useful for treatment of Alzheimer's disease. ... | 05/13/2008 |
| 7365196 | Sulphonamido-substituted bridged bicycloalkyl derivatives A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of and/or prevention of Alzheimer's disease. ... | 04/29/2008 |
| 7361657 | Respiratory syncytial virus replication inhibitors This invention concerns the use of compounds of formula (I) wherein −a1=a2−a3=a4—is a radical of formula —CH═CH—CH═CH—, —N═CH—CH═CH—, —CH═N—CH═CH—, —CH═CH—N═CH—, —CH═CH—C... | 04/22/2008 |
| 7357947 | Bone graft material incorporating demineralized bone matrix and lipids One embodiment of the invention is demineralized bone putty composition comprises: (1) demineralized bone matrix (DBM); and (2) a lipid fraction selected from the group consisting of lecithin and a mixture of lecithin and triglycerides containing unsaturated fatty a... | 04/15/2008 |
| 7348440 | Mitotic kinesin inhibitors The present invention relates to dihydropyrrole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comp... | 03/25/2008 |
| 7342039 | Substituted indole oximes The present invention relates to substituted indole oximes and methods of using them. ... | 03/11/2008 |
| 7338969 | Modulation of pathogenicity The present invention relates to the use of compounds of the general Formula (XIII): wherein A7 is C═O, C═S, SO2, CH—OR13, C═NR12... | 03/04/2008 |
| 7326695 | Anti-bacterial agents based upon oxoanion binding Compounds of the structure I: are useful for treating bacterial growth, wherein E is selected from the group consisting of B, P, and S, T1 and T2 are each independen... | 02/05/2008 |
| 7297193 | Wax-biocide wood treatment A method for preserving wood by contacting wood with an aqueous composition comprising a paraffin wax, at least one nonionic surfactant, and at least one organic wood preservative. ... | 11/20/2007 |
| 7291276 | Controlled production and release of oxygen activated biocide into holding tanks for RV's, boats and the like Waste in a black or gray water holding tank is treated by an oxygen activated biocide by the addition of tetra acetyl ethylene diamine (TAED) and a peroxygen compound. Hydrogen peroxide and/or peracetic acid are released over a period of time and thus maintained in ... | 11/06/2007 |