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| Number | Title | Issue Date |
| 8173681 | Method for the protection of materials The present invention relates to the use of the compound A) 4-(2,2-difluoro-1,3-benzodioxol-4-yl)pyrrole-3-carbonitrile(fludioxonil) as a microbicide for the protection of engineering or industrial materials, to mixtures containing such compound, and to the use of s... | 05/08/2012 |
| 8143293 | Kinase inhibitors useful for the treatment of myleoprolific diseases and other proliferative diseases Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant, melanomas, glioblastomas, ovarian cancer, pancreatic cancer, prostate cancer, lung cancers, breast cancers, kid... | 03/27/2012 |
| 8143294 | 2-sulfanyl-substituted imidazole derivatives and their use as cytokine inhibitors The invention relates to 2-thio-substituted imidazole derivatives of the Formula I, and to methods of use thereof. ... | 03/27/2012 |
| 8143292 | N-Thio-anthranilamid compounds and their use as pesticides N-Thio-anthranilamid compounds of formula (I) wherein A is a group selected from A1 and A2 wherein the variables and the indices are as defined per the descr... | 03/27/2012 |
| 8119665 | Aryl imidazoles and related compounds as C5a receptor modulators The invention provides packaged pharmaceutical preparations of Aryl substituted imidazoles, pyrazoles, pyridizines and related compounds of the Formula where the variables are defined herein. Such compounds are liga... | 02/21/2012 |
| 8084474 | Insecticides Compounds of formula (I) wherein the substituents are as defined in claim (1), and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula (I) can be used as agrochemical active ingredients and can be prepare... | 12/27/2011 |
| 8071629 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides A compound of general formula (I): A process for preparing this compound. A compound of general formula (II): A fungicide composition comprising a compound of general formula (I... | 12/06/2011 |
| 8063077 | Factor Xa inhibitors The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to intermediates used in making such compounds, pharmaceutical... | 11/22/2011 |
| 8063076 | Solid forms of 2-Chloro-4-[1-(4-fluoro-phenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]-pyridine The present invention relates to the mono-sulfate salt, crystalline forms A and B of the mono-sulfate salt, an amorphous form of the mono-sulfate salt, hemi-sulfate salts, and a crystalline form A of the hemi-sulfate salt of the compound 2-chloro-4-[1-(4-fluoro-phen... | 11/22/2011 |
| 8026260 | Histone deacetylase inhibitors with aryl-pyrazolyl-motifs The present invention relates to a novel class of histone deacetylase inhibitors with aryl-pyrazolyl motifs. The compounds of this invention can be used to treat cancer. The compounds of this invention are suitable for use in selectively inducing terminal differenti... | 09/27/2011 |
| 8017632 | Selective insecticides based on haloalkylnicotinic acid derivatives, anthranilic acid diamides, or phthalic acid diamides and safeners The present invention relates to the use of selective insecticidal compositions, characterized by an effective amount of an active compound combination comprising (a) (1) at least one haloalkylnicotinic acid derivative of the formula (I) ... | 09/13/2011 |
| 7994200 | Cycloalkane-substituted pyrazoline derivatives, their preparation and use as medicaments The present invention relates to Cycloalkane-substituted substituted pyrazoline compounds of formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and a... | 08/09/2011 |
| 7994201 | Anthranilamide compounds, process for their production and pesticides containing them Anthranilamide compounds, a process for their production, and pesticides containing these compounds as active ingredients. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any w... | 08/09/2011 |
| 7968573 | Hydrazide compound and pesticidal use of the same A hydrazide compound represented by the formula (1): (wherein R1, R2, R3, R4, A1, A2, J, Q and n are defined in the specification) has excellent pesticidal a... | 06/28/2011 |
| 7964620 | Imidazole derivatives The present invention relates to imidazole derivatives of formula I wherein R1, R2, R3, R4, X, Y and R are described hereinabove, or a pharmaceutically acceptable salt thereof. Th... | 06/21/2011 |
| 7960413 | Pyrazole compounds Compounds of the formula (I) and salts and solvates thereof, in which X, R1, R2, R3, R4, R5 and R6 have the meanings indicated in Claim 1, are suitable as ligands of 5 HT receptors. | 06/14/2011 |
| 7939550 | Aminopyrazole derivatives, process for the preparation thereof, and composition for preventing or treating ischemic diseases containing the same Provided are aminopyrazole derivatives, a process for the preparation thereof, and a composition for preventing or treating an ischemic disease containing the same. Since the aminopyrazole derivatives of the present invention can reduce an ischemic cell death signif... | 05/10/2011 |
| 7902231 | Anthropodicidal anthranilamides This invention provides compounds of Formula 1, their N-oxides and agriculturally suitable salts wherein R1, R2, R3, R4a, R4b and R | 03/08/2011 |
| 7902232 | Substituted arylpyrazoles This invention relates to a combination product comprising a range of 1-aryl-4 -cyclopropylpyrazoles in which there is at least one fluorine attached to the cyclopropyl ring, and one o more further therapeutic agents, particularly anti-parasitic agents. ... | 03/08/2011 |
| 7875634 | Cyano anthranilamide insecticides This invention provides compounds of Formula 1, N-oxides and suitable salts thereof wherein R1 is Me, Cl, Br or F; R2 is F, Cl, Br, C1-C | 01/25/2011 |
| 7868025 | Pesticide The present invention provides a composition comprising synergistic amounts of a compound of the formula (I) wherein X, E, R, A and Z are as defined herein, and at least one fungicidal active compound as defined herein. The... | 01/11/2011 |
| 7863299 | Triazolyl derivatives of azabicyclo [3.1.0] hexane as dopamine D3 receptor modulators The present invention relates to novel compounds of formula (IC) or a salt thereof: wherein: p is an integer ranging from 0 to 4; R1 is independently selected from a group consisting of:... | 01/04/2011 |
| 7829586 | Aryl-substituted nitrogen-containing heterocyclic compounds Disclosed is an aryl-substituted nitrogen-containing heterocyclic compound represented by the formula (I) below or a pharmaceutically acceptable salt thereof. This compound serves as nociceptin receptor antagonist and is useful as a pharmaceutical agent for treating... | 11/09/2010 |
| 7807698 | Azabicyclo[3.1.0]hexane derivatives as modulators of the dopamine D3 receptor The present invention relates to novel compounds of formula (I) or a pharmaceutically acceptable salt thereof: wherein G is selected from a group consisting of: phenyl, pyridyl, benzothiaz... | 10/05/2010 |
| 7803819 | DPP IV inhibitors The present invention relates to compounds of formula (I) wherein R1, R2, and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for... | 09/28/2010 |
| 7803821 | Fungicide N-cycloalkyl-carboxamide, thiocarboxamide and N-substituted-carboximidamide derivatives The present invention relates to N-cycloalkyl-carboxamide, N-cycloalkyl-thiocarboxamide and N-cycloalkyl-N-substituted carboximidamide derivatives of formula (I) wherein A represents carbo-linked, 5-membered heterocyclyl groups, T represents O, S, NRc, Nâ... | 09/28/2010 |
| 7803820 | 3-triazolylthiaalkyl-3-azabicyclo (3-1-O) hexanes and their use as dopamine D3 receptor ligands The present invention relates to novel compounds of formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 is hydrogen or C1-4alkyl; R... | 09/28/2010 |
| 7799809 | Carboxamide compounds and their use as calpain inhibitors The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carbo... | 09/21/2010 |
| 7799810 | Organic compounds The present invention concerns a compound of formula (I), or a pharmaceutically acceptable salt, or solvate thereof, wherein the groups Ri- Rs are defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibi... | 09/21/2010 |
| 7790756 | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases The present invention is concerned with novel compounds useful in the treatment of hyperproliferative diseases and mammalian cancers, especially human cancers. The invention also pertains to methods of modulating kinase activities, pharmaceutical compositions, and m... | 09/07/2010 |
| 7767696 | Pyrazole derivatives Compounds of the formula (I), in which R1 and R2 have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases, and can be employed, inter alia, for the treatment of tumours. | 08/03/2010 |
| 7767697 | Factor Xa inhibitors The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to intermediates used in making such compounds, pharmaceutical... | 08/03/2010 |
| 7759366 | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, process for preparing them, medicaments comprising these compounds, and their use This invention relates to arylaminoaryl-alkyl-substituted imidazolidone-2,4-diones of formula (I) and also to their physiologically tolerated salts: Wherein R, R′, R1 to R10, A, D, E, G, L and p are as defined herein. The... | 07/20/2010 |
| 7728011 | Dermally applicable liquid formulations for controlling parasitic insects on animals The present invention relates to novel skin-friendly dermally applicable liquid formulations comprising permethrin and agonists or antagonists of nicotinic acetylcholine receptors of insects for controlling parasitic insects on animals. ... | 06/01/2010 |
| 7728012 | Carboxamide compounds and their use as calpain inhibitors The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carbo... | 06/01/2010 |
| 7723363 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides A compound of general formula (I). A process for preparing this compound. A fungicidal composition comprising a compound of general formula (I). A method for treating plants by applying a compound of general formula (I) or a composition comprising it. | 05/25/2010 |
| 7696233 | Method for controlling particular insect pests by applying anthranilamide compounds This invention pertains to a method for controlling lepidopteran, homopteran, hemipteran, thysanopteran and coleopteran insect pests comprising contacting the insects or their environment with an arthropodicidally effective amount of a compound of Formula I, its N-o... | 04/13/2010 |
| 7696232 | Anthranilamide arthropodicide treatment This invention pertains to methods for protecting a propagule or a plant grown therefrom from invertebrate pests comprising contacting the propagule or the locus of the propagule with a biologically effective amount of a compound of Formula I, its N-oxide or an agri... | 04/13/2010 |
| 7671072 | Aminopyrazole derivatives as GSK-3 inhibitors The present invention provides compounds of formula (I) the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds, stereoisomers, and prodrugs, wherein R1, R2, and R3 are as defined herein; ph... | 03/02/2010 |
| 7666882 | Anthranilamide insecticides This invention provides compounds of Formula I, N-oxides and suitable salts thereof wherein Y and V are each independently N or CR4a; W is N, CH or CR6; and R1 through R6, and n a... | 02/23/2010 |
