An armor with rollers is provided that enables a user to move in all positions by rolling on a hard and smooth surface while constantly varying his bearing points on the ground.
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| Number | Title | Issue Date |
| 8183261 | Microorganism control agent and stabilizing method Disclosed is a microorganism control agent containing not less than 1% by weight but less than 10% by weight of N,N′-hexamethylenebis(4-carbamoyl-1-decylpyridinium bromide), not less than 35% by weight but less than 60% by weight of at least one alcohol having 2 o... | 05/22/2012 |
| 8158654 | Pyridine non-classical cannabinoid compounds and related methods of use Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors. ... | 04/17/2012 |
| 8143288 | Inhibitors of HCV replication Compounds having the structure of formula I are described. The compounds can inhibit hepatitis C virus (HCV) replication, and in particular can inhibit the function of the HCV NS5A protein. ... | 03/27/2012 |
| 8101636 | Linear dicationic terphenyls and their aza analogues as antiparasitic agents Novel aza analogues of dicationic terphenyl compounds for use in combating microbial infections are described. Also described are processes for synthesizing the compounds. The presently disclosed compounds can include those of the formulas: | 01/24/2012 |
| 8084470 | Substituted nicotinamide compounds and uses thereof Substituted nicotinamide compounds corresponding to formula I a process for their preparation, pharmaceutical compositions containing these compounds, and the use thereof for the treatment or inhibition conditions such as p... | 12/27/2011 |
| 8071626 | Chelating agents and highly luminescent and stable chelates and their use This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relat... | 12/06/2011 |
| 8067440 | Phosphonium salts derivatives and uses thereof There are provided compounds of formulas (VA), (VIA), (VIIA) (IXA), (XIA), (XIIA), (XIIIA), and (XIVA): wherein A, Z, R2, X−, and L2 represent various different po... | 11/29/2011 |
| 8063072 | Heterocyclic antiviral compounds Compounds having the formula I wherein R1, R2, R3, R4, and R5 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and... | 11/22/2011 |
| 8053449 | Method for inhibiting AGE complex formation Various methods of administering medication(s) that inhibit the nonenzymatic formation of glycation and dehydration condensation complexes known as advanced glycation end-products (AGEs) or modulate the advanced glycation end-product receptor (RAGE) are provided. Al... | 11/08/2011 |
| 8048896 | Methods for inhibiting and breaking AGE complex formation Various methods of administering medication(s) that inhibit the nonenzymatic formation of glycation and dehydration condensation complexes known as advanced glycation end-products (AGEs) or modulate the advanced glycation end-product receptor (RAGE) are provided. | 11/01/2011 |
| 8030332 | Potassium channel inhibitors The present invention relates to dipyridin-3-ylmethoxy compounds and derivatives thereof having the structure I useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 10/04/2011 |
| 7989476 | Electron-transporting materials and processes for making the same Compound of formula C is made by reacting a compound of formula A with an pyridyl boronic acid or pyridyl borate ester to form a compound of formula B; and combining the compound of formula B with a... | 08/02/2011 |
| 7973059 | Potassium channel inhibitors The present invention relates to compounds having the structure useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 07/05/2011 |
| 7964619 | Teraryl components as antiparasitic agents Disclosed herein are novel dicationic teraryl compounds and their aza analogues, including compounds of Formula (IIe): wherein p and q are each 0 and each A, Y and Z is CR4. An exemplary compound of Formula (IIe)... | 06/21/2011 |
| 7919511 | Certain chemical entities, compositions, and methods Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, and chemical entities, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described. ... | 04/05/2011 |
| 7888374 | Inhibitors of c-jun -terminal kinases The present invention relates to compounds that are inhibitors of c-jun N-terminal kinase 1, 2, or 3 (JNK1, JNK2, or JNK3), compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders regulated by the activation of ... | 02/15/2011 |
| 7875633 | Phenylpyridone derivative A compound represented by the formula (I) is contained as an active ingredient: wherein R1 and R2 independently represent a hydrogen atom, a lower alkyl group or the like, or R1 together wit... | 01/25/2011 |
| 7872029 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present inventi... | 01/18/2011 |
| 7851489 | Pyridinone compounds The invention is directed to pyridinone compounds useful for modulating Met kinase, having the following structure: and is further directed to pharmaceutical compositions comprising the compound; and methods for treating pr... | 12/14/2010 |
| 7846947 | Use of octenidine dihydrochloride in semisolid preparations The invention relates to the use of octenidine dihydrochloride for manufacturing a semisolid pharmaceutical composition for the treatment of wounds, atopic dermatitides, infected eczemas, dermatomycoses, vaginal infections, acne, herpes and/or for controlling multid... | 12/07/2010 |
| 7829584 | Pyridines and pyridine N-oxides as modulators of thrombin The present invention describes compounds of Formula I: wherein W, X, Y, Z, and Q are defined herein, or a pharmaceutically acceptable salt thereof, for the prophylaxis, or treatment of diseases and conditions related to th... | 11/09/2010 |
| 7754738 | Pyrazole and pyrrole carboxamide insecticides This invention provides compounds of Formula (I), N-oxides and salts thereof wherein: A is O or S; B is a phenyl ring or a pyridine ring, each ring optionally substituted with 1 to 5 R; J is a pyrazole or a pyrrole heterocyclic ring system as defined herein; and; R | 07/13/2010 |
| 7625930 | Chelating agents and highly luminescent and stable chelates and their use This invention relates to a group of novel chelating agents, novel chelates, biomolecules labeled with said chelates or chelating agents as well as solid supports conjugated with said chelates, chelating agents or labeled biomolecules. Especially the invention relat... | 12/01/2009 |
| 7612097 | Method for producing bactericidal pyridine compound and bactericidal pyridine compound Provided are novel pyridine compounds represented by the following formula (7): wherein R1 and R4 may be the same or different and are each a linear or branched alkyl group having 1 to 4 carbon atoms; ... | 11/03/2009 |
| 7572815 | Amide derivative Amide derivatives represented by the formula (I): wherein: A is a cycloalkyl group, an aryl group or a heteroaryl group; X is a nitrogen atom or CR17; Y is —NRa—, —(CRbRb′)m-, and ... | 08/11/2009 |
| 7534802 | Compounds having 4-pyridylalkylthio group as substituent A subject of the present invention is to provide a novel aromatic five- or six-memberd heterocyclic derivative having 4-pyridylalkylthio as a substituent or a salt thereof which is useful as a pharmaceutical. Compound represented by the following general formula [I]... | 05/19/2009 |
| 7417041 | Imidazopyrimidines as transforming growth factor (TGF) inhibitors Novel fused heteroaromatic compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of tran... | 08/26/2008 |
| 7414060 | Pyridine-2-carboxyamide derivatives The invention relates to compounds of formula I: wherein R1 to R3 are as defined in the specification, to processes for their preparation, to pharmaceutical compositions containing them, and to methods... | 08/19/2008 |
| 7410979 | Synergistically effective combinations of dihaloacetamide compounds and interferon or ribavirin against HCV infections The present invention relates to anti-HCV dihaloacetamide compounds in synergistic combination with an interferon and/or ribavirin and pharmaceutical compositions thereof for inhibition of the replication of HCV virus. The present invention also relates to the use o... | 08/12/2008 |
| 7407972 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade The present invention provides compounds of Formula (I): wherein A, B, C, G, and W1 have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful to treat thro... | 08/05/2008 |
| 7402683 | Cinnamic acid amides The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection. ... | 07/22/2008 |
| 7388021 | Urea antagonists of P2Yreceptor useful in the treatment of thrombotic conditions The present invention provides novel pyridyl or phenyl ureas and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating disease... | 06/17/2008 |
| 7371763 | Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas The invention relates to a group of quinolyl, isoquinolyl and pyridyl ureas, their the use in treating raf mediated diseases, and pharmaceutical compositions which contain these ureas for use in such therapy. ... | 05/13/2008 |
| 7371766 | Curcumin analogs with anti-tumor and anti-angiogenic properties The present invention is directed to curcumin analogs exhibiting anti-tumor and anti-angiogenic properties, pharmaceutical formulations including such compounds and methods of using such compounds. ... | 05/13/2008 |
| 7351722 | Use of Mangafodipir for treating oxidative stress effects The invention concerns the use of Mangafodipir to obtain a medicine for preventive or curative treatment of hepatocellular deficiencies. ... | 04/01/2008 |
| 7351742 | Sulfonamide derivatives for the treatment of diseases The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the ... | 04/01/2008 |
| 7338950 | Amide compounds as ion channel ligands and uses thereof Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals ... | 03/04/2008 |
| 7332602 | Pyridyl substituted heterocycles useful for treating or preventing HCV infection The present invention relates to pyridyl substituted heterocycles and hydro isomers thereof and pharmaceutical compositions thereof that inhibit replication and/or proliferation of HCV virus. The present invention also relates to the use of the pyridyl heterocycles ... | 02/19/2008 |
| 7326723 | Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same The present invention relates to compounds of formula (I): in which X represents N or CH; R1 represents a hydrogen or halogen atom or a CF3 group; n is an ... | 02/05/2008 |
| 7312235 | Benzamide inhibitors of factor Xa Novel benzamide compounds, their salts and compositions related thereto having activity against mammalian Factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders. ... | 12/25/2007 |