Did You Know...
...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8101634 | Bicyclic compounds and use as antidiabetics The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds. ... | 01/24/2012 |
| 8084465 | Derivatives of pryidone and use thereof The present invention provides N-substituted-2(1H) pyridones or the pharmaceutical acceptable salts thereof, and the pharmaceutical preparations containing the compounds. The compounds of the present invention can be used to treat various fibrotic diseases effective... | 12/27/2011 |
| 8080564 | Hemodynamics improving agent Agents which contains a serotonin derivative as an active ingredient are effective for improving hemodynamics and for preventing or improving deterioration of hemodynamics associated with aging and progression of cardiovascular diseases. ... | 12/20/2011 |
| 8053447 | 11β-hydroxysteroid dehydrogenase type 1 active compounds A novel class of compounds of the general formula (I), their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. The present compounds modulate the activity of 11β-hydroxy-stero... | 11/08/2011 |
| 8026254 | Therapeutic agents useful for treating pain 4-Tetrazolyl-4-phenylpiperidine Compounds, compositions comprising an effective amount of a 4-Tetrazolyl-4-phenylpiperidine Compound, methods for treating or preventing pain or diarrhea in an animal comprising administering to an animal in need thereof an effective ... | 09/27/2011 |
| 8022087 | Derivatives of pyridone and use thereof The present invention provides N-substituted-2(1H) pyridones or the pharmaceutical acceptable salts thereof, and the pharmaceutical preparations containing the compounds. The compounds of the present invention can be used to treat various fibrotic diseases effective... | 09/20/2011 |
| 8008325 | Plasma carboxypeptidase B inhibitors Compounds of the following formula (I), for example: wherein R1, R2, R3, and R4 are described herein, are useful as inhibitors of plasma carboxypeptidase B. Pharmaceutical composi... | 08/30/2011 |
| 7973054 | Use of glucosidase inhibitors for therapy of mucovisidosis A method provides for the use of glycosidase inhibitors selected from compounds of general formula (1), wherein R1 represents a CH3 group, or CH2OH, R2 represents H or an alkyl group having 1-5 carbon atoms, or R1 | 07/05/2011 |
| 7964617 | Methods for treating parkinsons disease and parkinsonism Described is a method for treating an individual having a neurological disorder with an associated mutation or mutations in a gene encoding a lysosomal enzyme. Specifically, the individual is administered a specific pharmacological chaperone for the lysosomal enzyme... | 06/21/2011 |
| 7960410 | Method for treating insulin resistance, abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids with a cortisol inhibitor The invention concerns the use of ketoconazole and derivatives having a corresponding biological activity, and combinations thereof, in the treatment of abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids. ... | 06/14/2011 |
| 7932267 | Use of α-glucosidase inhibitors to treat alphavirus infections The present invention provides methods for treating a flavivirus infection, including hepatitis C virus (HCV) infection, in an individual suffering from a flavivirus infection. In some embodiments, the methods involve administering to an individual in need thereof a... | 04/26/2011 |
| 7897620 | Methods of using anti-inflammatory compounds The invention relates to the use of 3-(2′,2′-dimethylpropanoylamino)-tetrahydropyridin-2-one for preparing a medicament intended to prevent or treat inflammatory disorders. ... | 03/01/2011 |
| 7884115 | Methods and compositions for the treatment of pain and other neurological conditions Methods and compositions for the treatment of conditions including stress-associated, chronic pain, and neurodegenerative conditions in a mammal using a composition comprising NB-DNJ or a compound structurally similar thereto. ... | 02/08/2011 |
| 7829579 | Method for the treatment of neurological disorders by enhancing the activity of β-glucocerebrosidase Provided is a method of increasing the stability of wild-type β-glucocerebrosidase. Also provided are methods of treating and/or preventing an individual having a neurological disease in which increased expression or activity of β-glucocerebrosidase in the central... | 11/09/2010 |
| 7825134 | Amelioration of cataracts, macular degeneration and other ophthalmic diseases Ophthalmically acceptable compositions used in arresting the development of macular degeneration, retinopathy, glaucoma, eyelid disorders, corneal disease, or uveitis are disclosed. The compositions comprise a pharmaceutically acceptable carrier or diluent and at le... | 11/02/2010 |
| 7825133 | Derivatives of pyridone and the use of them The present invention provides N-substituted-2(1H) pyridones or the pharmaceutical acceptable salts thereof, and the pharmaceutical preparations containing the compounds. The compounds of the present invention can be used to treat various fibrotic diseases effective... | 11/02/2010 |
| 7812033 | Method for increasing the activity of acid-β-galactosidase Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method ... | 10/12/2010 |
| 7807695 | Cosmetic use of piperidine derivatives The present invention relates to the cosmetic use, as an agent for combating wrinkles, especially expression wrinkles, and/or for dencontracting the skin and/or relaxing the features, of at least one piperidine derivative chosen from the compounds of formula (I): | 10/05/2010 |
| 7776884 | Cyclic derivatives as modulators of chemokine receptors activity The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of rheumatoid arthritis, multiple sclerosis, atherosclerosis, asthma, restin... | 08/17/2010 |
| 7767692 | 1-amidomethylcarbonyl-piperidine compounds, methods and intermediate products for the production thereof and pharmaceutical formulations containing said compounds 4-substituted 1-amidomethylcarbonyl-piperidine compounds having motilin-agonistic properties and their acid addition salts, pharmaceutical compositions containing these compounds, processes and intermediate products for the preparation of these compounds, and method... | 08/03/2010 |
| 7767693 | Hsp90 family protein inhibitors The present invention provides Hsp90 family protein inhibitors comprising, as an active ingredient, a benzoyl compound represented by general formula (I): (wherein n represents an integer of 0 to 10; R1 represent... | 08/03/2010 |
| 7745464 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners The present invention relates to heterocyclic compounds that bind to Bcl proteins and inhibit Bcl function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer. ... | 06/29/2010 |
| 7741340 | Hydroxy piperidine derivatives to treat gaucher disease The present invention provides novel hydroxy piperidine (HP) derivatives having (i) a positive charge at the position corresponding to the anomeric position of a pyranose ring; (ii) a short, flexible linker emanating from the corresponding position of the ring oxyge... | 06/22/2010 |
| 7723357 | Thalidomide and thalidomide derivatives for treating spinal disorders mediated by nucleus pulposus Described herein are methods and compositions for the treatment of spinal disorders mediated by nucleus pulposus. The compositions can include thalidomide or a thalidomide derivative. ... | 05/25/2010 |
| 7718673 | Isonipecotamides for the treatment of integrin-mediated disorders The invention is directed to novel isonipecotamide derivatives of Formula (I): which are useful in treating integrin-mediated disorders. ... | 05/18/2010 |
| 7700622 | p-38 kinase inhibitors Compounds and compositions for modulating the activity of p38 kinases are provided, including p38α and p38β kinase. Methods for treating, preventing or ameliorating one or more symptoms of a p38 kinase mediated disease or disorder are also provided. ... | 04/20/2010 |
| 7691880 | Methylphenidate solution and associated methods of administration and production A methylphenidate solution and associated methods of administration and production, which includes methylphenidate and at least one organic acid dissolved in a solvent system, where the solvent system includes at least one non-aqueous solvent. The solvent system may... | 04/06/2010 |
| 7687518 | Therapeutic agents useful for treating pain 4-Tetrazolyl-4-phenylpiperidine Compounds, compositions comprising an effective amount of a 4-Tetrazolyl-4-phenylpiperidine Compound, methods for treating or preventing pain or diarrhea in an animal comprising administering to an animal in need thereof an effective ... | 03/30/2010 |
| 7652038 | Methods of reducing angiogenesis The present invention provides methods of reducing angiogenesis in an individual. The methods generally involve administering to the individual an effective amount of a nicotinic acetyl choline receptor antagonist. The methods are useful to treat conditions associat... | 01/26/2010 |
| 7622485 | Method of enhancing lysosomal α-galactosidase A A method of enhancing the activity of lysosomal α-Galactosidase A (α-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds. ... | 11/24/2009 |
| 7615566 | Substituted pyrrolidine and related compounds This invention is directed to compounds of formula I: wherein R1-R5 and a-e are as defined in the specification; or pharmaceutically-acceptable salt or solvate or stereoisomer thereof. The invention also... | 11/10/2009 |
| 7612093 | Compositions of treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds in combination therapy Provided are methods and compositions for treating hepatitis virus infections in mammals, especially humans. The methods comprise (1) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds in combination with nucleoside antiviral agents, nucleotide a... | 11/03/2009 |
| 7598269 | Methods and compositions for treating amyloid-related diseases Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease. ... | 10/06/2009 |
| 7589107 | Amelioration of vitrectomy-induced cataracts Methods to prevent, inhibit, or slow the development of vitrectomy-induced cataracts are disclosed. The methods comprise administering to the eye of a subject a composition comprising an ophthalmologically acceptable carrier or diluent and at least one hydroxylamine... | 09/15/2009 |
| 7576101 | Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents The application provides for methods and compositions for inhibiting demyelination, promoting remyelination and/or treating paralysis in a subject in need thereof. Preferably, such compositions include immunoglobulins (e.g., antibodies, antibody fragments, and recom... | 08/18/2009 |
| 7572811 | Immunosuppressant compounds and compositions The present invention relates to immunosuppressant, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by... | 08/11/2009 |
| RE40851 | 3,3-diphenylpropylamines, their use and preparation The invention relates to 3,3-diphenylpropylamines of formula (I), wherein R1 signifies hydrogen or methyl, R2 and R3 independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphamoyl or halogen, and X represents a terti... | 07/14/2009 |
| 7528152 | Hemiasterlin derivatives and uses thereof in the treatment of cancer The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R1 | 05/05/2009 |
| 7514453 | Method for enhancing mutant protein activity Provided is a method for enhancing the activity of a protein, which protein when mutated, folds in an incorrect conformation in the endoplasmic reticulum, by contacting the protein with an effective amount of a compound which specifically binds to the protein and in... | 04/07/2009 |
| 7501439 | Tartrate salt of isofagomine and methods of use A novel tartaric acid salt of Isofagomine (Isofagomine tartrate) that can be used for the treatment of Gaucher disease is provided. The invention also provides a crystalline form of isofagomine tartrate, method for preparing the salt, a pharmaceutical composition co... | 03/10/2009 |
