Bizarre Patents
Safety System For Remove a Rider From a Vehicle by Deploying a Parachute
Methods and apparatus for reducing the velocity of a rider in or on an open cockpit vehicle when the rider is thrown from the vehicle.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8168649 | Niacin receptor agonists, compositions containing such compounds and methods of treatment The present invention encompasses compounds of Formula (I): as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.... | 05/01/2012 |
| 8119655 | Kinase inhibitors Compounds, pharmaceutical compositions, kits and methods are provided for use with kinases that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. ... | 02/21/2012 |
| 8076352 | Administration of carboline derivatives useful in the treatment of cancer and other diseases In accordance with the present invention, compounds that inhibit the expression of VEGF post-transcriptionally have been identified, and compositions, and methods for the administration and use of those compounds. provided. In one aspect of the invention, compounds ... | 12/13/2011 |
| 8076353 | Inhibition of VEGF translation In accordance with the present invention, methods for inhibiting the translation of VEGF and methods for decreasing VEGF level by inhibiting VEGF translation are provided. In another aspect of the invention, compounds that inhibit the 5′-UTR-dependent translation ... | 12/13/2011 |
| 8063061 | 6-heteroarylpyridoindolone derivatives, their preparation and therapeutic use thereof The disclosure relates to compounds of formula (I): wherein R1, R2, R3, R4, are R5 are as defined in the disclosure; their preparation method, compositions containing t... | 11/22/2011 |
| 8058288 | Amido compounds and their use as pharmaceuticals The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases... | 11/15/2011 |
| 8034826 | Cycloalkane[B]azaindole antagonists of prostaglandin Dreceptors Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination ... | 10/11/2011 |
| 8012991 | Pyridoindolone derivatives substituted in the 3-position by a phenyl, their preparation and their application in therapeutics The present disclosure relates to pyridoindolone derivatives of general formula (I): to processes for preparing the same and to their use in therapeutics. ... | 09/06/2011 |
| 8003661 | Naphthalene and quinoline sulfonylurea derivatives as EP4 receptor antagonists The invention is directed to naphthalene and quinoline sulfonylurea derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutic... | 08/23/2011 |
| 7998971 | Combinations containing a 4-acylaminopyridine derivative The instant disclosure describes compositions and methods for treating diseases and conditions of the central and peripheral nervous system. The disclosure includes compositions and methods based on use of a 4-acylaminopyridine derivative in combination with one or ... | 08/16/2011 |
| 7968562 | Pharmaceutical formulations comprising an immune response modifier Pharmaceutical formulations comprising an immune response modifier (IRM) chosen from imidazoquinoline amines, imidazotetrahydroquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, thiazolo-quinoli... | 06/28/2011 |
| 7956064 | Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators The invention relates in part to fused tricyclic compounds having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. The fused tricyclic compounds ... | 06/07/2011 |
| 7915280 | Compounds and their uses This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP. ... | 03/29/2011 |
| 7910600 | Therapeutic kinase modulators The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, and modulating protein kinase activity. Molecules of the invention can modulate casein kinase (CK) activity. The inve... | 03/22/2011 |
| 7767689 | Carboline derivatives useful in the treatment of cancer In accordance with the present invention, compounds that inhibit the expression of VEGF post-transcriptionally have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the inhibition of VEGF production, in the tre... | 08/03/2010 |
| 7745458 | Azabicyclo (3, 1, 0) hexan derivatives useful as modulators of dopamine D3 receptors The present invention relates to novel compounds of formula (I) or a salt thereof: wherein: p is 0, 1, 2, 3, 4 or 5; R1 is independently selected from a group consisting of: halogen, hyd... | 06/29/2010 |
| 7732461 | Tryclic nitrogen containing compounds and their use as antibacterials Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials. ... | 06/08/2010 |
| 7732460 | Heterocyclic compounds, their preparation and their use as antibacterials Tricyclic nitrogen containing compounds of formula (I) and their use as antibacterials. ... | 06/08/2010 |
| 7723352 | Isoquinolinone potassium channel inhibitors The present invention relates to compounds having the structure (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. ... | 05/25/2010 |
| 7718667 | Fused aminopiperidines as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes The present invention is directed to novel substituted fused aminopiperidines which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DPP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV en... | 05/18/2010 |
| 7652031 | Compounds which mimic the chemical and biological properties of discodermolide Compounds which mimic the chemical and/or biological activity of discodermolide are provided. ... | 01/26/2010 |
| 7618980 | Pyrrolo(oxo)quinolines as 5HT ligands The present application provides pyrrolo(oxo)isoquinolines as modulators of serotonin receptors, pharmaceutical compositions containing such modulators and methods for treating various diseases, conditions and disorders associated with modulation of serotonin recept... | 11/17/2009 |
| 7612083 | Urea substituted imidazoquinoline ethers Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and urea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are us... | 11/03/2009 |
| 7608625 | Method for treating bruxism and bruxism-related diseases The present invention provides a preventive or therapeutic agent for bruxism or bruxism-related diseases that contains as an active ingredient at least one selected from the group consisting of proton pump inhibitors, histamine H2 receptor antagonists, an... | 10/27/2009 |
| 7572805 | Pyrrolo(oxo)isoquinolines as 5HT ligands The present application describes compounds according to Formula I, pharmaceutical compositions, comprising at least one compound according to Formula I and optionally at least one additional therapeutic agent and methods of treating various diseases, conditions and... | 08/11/2009 |
| 7524857 | Pharmaceutical combinations based on pyridoindolone derivatives and anticancer agents The invention relates to the combination of compounds of formula: with one or more anticancer agents. ... | 04/28/2009 |
| 7501436 | 5-HT3 receptor antagonists and methods of use The subject invention provides useful and novel 5-HT3 antagonists. The subject invention also provides methods for synthesizing the compounds of invention. The invention also provides methods for the treatment of irritable bowel syndrome and other such conditions. | 03/10/2009 |
| 7470704 | Benzonaphthyridines The compounds of formula I in which R1, R2, R3, R4, R5, R6 and n have the meanings as indicated in the description, are novel effective PDE3/4 inhibitors. ... | 12/30/2008 |
| 7449476 | Tetrahydrocarboline antiviral agents The invention encompasses a series of tetrahydrocarboline compounds of Formula I which inhibit HIV entry by attaching to the exterior viral envelop protein gp120 and interrupting the viral entry process, possibly by interfering with the cellular receptor CD4. This a... | 11/11/2008 |
| 7439253 | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors The invention relates to novel heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a method for preparing these compounds, and to their use as medicaments, in p... | 10/21/2008 |
| 7419985 | 4-Phenyl substituted tetrahydroisoquinolines and therapeutic use thereof Compounds are provided that, by way of their selective neurotransmitter binding useful for the treatment of various neurological and psychological disorders, e.g., ADHD. Such compounds are 4-phenyl substituted tetrahydroisoquinolines having the Formula IA, IB, IIA, ... | 09/02/2008 |
| 7408064 | Carbazole derivatives and their use as NPY5 receptor antagonists The use of a compound of formula (I) in the manufacture of a medicament for the treatment, in a warm-blooded animal, of disorders mediated by the neuropeptide Y5 receptor: wherein: R1... | 08/05/2008 |
| 7390818 | Pyridoindolone derivatives substituted in the 3-position by a phenyl, their preparation and their application in therapeutics The present invention relates to pyridoindolone derivatives substituted in the 3-position by a phenyl of general formula (I): to processes for preparing the same and to their use in therapeutics. ... | 06/24/2008 |
| 7371721 | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes The present invention relates to methods for prevention and treatment of bone-related disorders and calcium homeostasis related syndromes using a GLP-2 molecule or GLP-2 activator either alone or in combination with another therapeutic. The present invention also en... | 05/13/2008 |
| 7365089 | Triazolo-quinolin derivatives useful as adenosine receptor ligands The present invention relates to adenosine A3? receptor ligands of the general formula (I), within those preferably antagonists, as well as their salts, solvates and isomers, and the pharmaceutical compositions containing them, to the use of the compounds of the gen... | 04/29/2008 |
| 7348336 | Substituted β-carbolines The subject matter of the present invention is directed to novel substituted β-carbolines, and specifically compounds of the formula I, which are suitable for the production of pharmaceuticals for the prophylaxis and thera... | 03/25/2008 |
| 7335772 | 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates The invention relates to a process for the synthesis of 1H-imidazo[4,5-c]quinoline 4-cyano and 1H-imidazo[4,5-c]quinoline 4-carboxamide intermediates useful in preparing 1H-imidazo[4,5-C]quinoline 4-amines, a process for preparing 1H-imidazo[4,5-C]quinoline 4... | 02/26/2008 |
| 7329666 | Derivatives of variolin B The invention provides antitumour compounds of formula (I), wherein R1 is an aromatic substituent; R2 is hydrogen or a substituent when the dotted line is absent, or R2 is absent when the dotted line represents a bond to give a doubl... | 02/12/2008 |
| 7326784 | Intermediates for the preparation of tricyclic dihydropyrano-imidazo-pyridines derivatives The invention relates to compounds of the formula 1, in which R1, R2, R3, Arom and PG have the meanings as indicated in the description. These compounds are valuable intermediates for the preparation of pharmaceu... | 02/05/2008 |
| 7323473 | Condensed indoline derivatives and their use as 5-HT, in particular 5-HT, receptor ligands A chemical compound of formula (I) wherein R1 and R2 are independently selected from hydrogen and alkyl; R3 is alkyl; R4 and R5 are selected from hydrogen and alkyl; R6 and R7 are independe... | 01/29/2008 |
