Bizarre Patents
A Receptacle for supporting, rotating and sculpting a portion of ice cream or similarly malleable food while it is being consumed.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8188079 | 3-amino-5-phenyl-5,6-dihydro-2H-[1,4]oxazines The present invention relates to 3-Amino-5-phenyl-5,6-dihydro-2H-[1,4]oxazines of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as ther... | 05/29/2012 |
| 8178528 | Histamine H3 receptor agents, preparation and therapeutic uses The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof which have histamine—H3 receptor antagonist or inverse agonist activity, as well as methods and intermediates for preparing such compounds. In another embod... | 05/15/2012 |
| 8173651 | Pyridine compounds This invention features compounds of formula (I): pharmaceutical compositions of the compounds, and methods of using the compounds for the treatment of, inter alia, IL-12-related diseases and disorders. ... | 05/08/2012 |
| 8148373 | Compounds The present invention relates to spirocyclic amide derivatives of the formula I, pharmaceutically acceptable salts thereof, a process for their preparation, pharmaceutical compositions containing them, and their use in ther... | 04/03/2012 |
| 8129376 | Piperidine derivatives as inhibitors of stearoyl-CoA desaturase The present invention relates to piperidine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds. ... | 03/06/2012 |
| 8124605 | Compositions and methods for modulating a kinase cascade The invention relates to compounds and methods for modulating one or more components of a kinase cascade. ... | 02/28/2012 |
| 8097624 | Cycloalkyl derivatives of 3-hydroxy-4-pyridinones The present invention provides an cycloalkyl derivative of 3-hydroxy-4-pyridinone which is useful for the chelation of metal ions such as iron. Its preparation and use is described. In particular, the invention concerns the removal of iron in chemical and biological... | 01/17/2012 |
| 8076329 | Histamine H3-receptor ligands and their therapeutic applications The present patent application concerns compounds of formula (I) with R1 and R2 taken together with the nitrogen atom to which they are attached, form a mono or bicyclic saturated nitrogen-containing ring; their preparation and their use as a H3 receptor ligand for ... | 12/13/2011 |
| 8071594 | Substituted diketopiperazines and their use as oxytocin antagonists Compounds of formula (1) wherein R1 is 2-indanyl, R2 is 1-methylpropyl, R3 is 2-methyl-1,3-oxazol-4-yl and R4 and R5 together with the notrogen atom to which they are a... | 12/06/2011 |
| 8063043 | Salts of N-[6-cis-2,6-dimethylmorpholin-4-yl)pyridine-3-yl]-2-methyl-4′-(trifluoromethoxy)[1,1′-biphenyl]-3-carboxamide Salts of N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridine-3-yl]-2-methyl-4′-(trifluoromethoxy)[1,1′-biphenyl]-3-carboxamide are prepared and characterized. ... | 11/22/2011 |
| 8026237 | Pyrrole derivatives as pharmaceutical agents Compounds, compositions and methods for modulating the activity of receptors are provided. In particular compounds and compositions are provided for modulating the activity of receptors and for the treatment, prevention, or amelioration of one or more symptoms of di... | 09/27/2011 |
| 8017607 | N-substituted-pyrrolidines as inhibitors of MDM2-P-53 interactions There are provided compounds of the formula wherein X, Y, R1, R2, R3, R3, R4, and R5 are as described herein and enantiomers and pharmaceutically a... | 09/13/2011 |
| 8012969 | 11C-labeled benzyl-lactam compounds and their use as imaging agents The invention relates to “C-labeled compounds, their preparation, compositions comprising an effective amount of a “C-labeled compound, and the use of a “C-labeled compound as a radiopharmaceutical for positron emission tomography. ... | 09/06/2011 |
| 8012970 | Derivatives of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine, synthesis process and uses thereof The present invention concerns pyrrole compounds, derivatives of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine (BM212). The invention concerns the use of the described compounds as antitubercular agents having high activity and low t... | 09/06/2011 |
| 8008296 | Histamine H3 receptor agents, preparation and therapeutic uses The present invention discloses novel compounds of Formula I or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention d... | 08/30/2011 |
| 8003642 | Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient The compound represented by formula (I), a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof specifically binds CCR5, so it is useful for preventing and/or treating CCR5-related diseases, for example, various inflammatory diseases (asthma, ne... | 08/23/2011 |
| 8003641 | Compositions and methods of treating cell proliferation disorders The invention relates to compounds and methods for treating cell proliferation disorders. ... | 08/23/2011 |
| 7998959 | Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1 and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydr... | 08/16/2011 |
| 7964596 | Therapeutic compounds Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein Y, A, B, and J are as described. Methods, compositions, and medicaments related thereto are also disclosed.... | 06/21/2011 |
| 7956052 | Modulators of ATP-binding cassette transporters Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The ... | 06/07/2011 |
| 7951804 | Piperidinyl compounds Novel compounds of the formula (I) in which D, E, Q, T, X, Y, Z, Z′, R1, R4 and R4′ have the meanings indicated, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic dis... | 05/31/2011 |
| 7947680 | Adamantyl diamide derivatives and uses of same The present invention provides adamantyl-diamide derivatives of formula (I): wherein R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and ... | 05/24/2011 |
| 7939529 | Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof The invention relates to compositions comprising 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts. More specifically, the invention provides an efficient process for the synthesis of 2-(5-(4-(2-morpholinoe... | 05/10/2011 |
| 7935697 | Compositions for modulating a kinase cascade and methods of use thereof The invention relates to compositions comprising 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts. The invention provides an efficient process for the synthesis of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi... | 05/03/2011 |
| 7932252 | Aryl sulfonamides The present invention relates to compounds that modulate various chemokine receptors. These compounds are useful for treating inflammatory and immune diseases. ... | 04/26/2011 |
| 7928103 | Compounds which modulate the CB2 receptor Compounds of formula (I) are disclosed. Compounds according to the invention are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain. | 04/19/2011 |
| 7906510 | Amide derivative and pharmaceutical composition containing the same Disclosed is a compound having a strong affinity to serotonin-4 receptors, which is useful as an enterokinesis-promoting agent or a digestive tract function-improving agent. Specifically, disclosed is a compound represented by Formula (1) or a pharmaceutically accep... | 03/15/2011 |
| 7902191 | Histamine H3 receptor antagonists, preparation and therapeutic uses The present invention discloses novel compounds of Formula I or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceuti... | 03/08/2011 |
| 7893061 | Alkyne-substituted pyridone compounds and methods of use The present invention comprises a new class of compounds capable of modulating the c-kit receptor and, accordingly, useful for treatment of c-kit mediated diseases, including various inflammatory, fibrotic and/or mast cell mediated diseases such as mastocytosis. The... | 02/22/2011 |
| 7893062 | Pyrrolidine derivatives as dual NK1/NK3 receptor antagonists The invention relates to pyrrolidine derivatives of formula wherein R1, R2, R3, n, and o are defined in the specification and to pharmaceu... | 02/22/2011 |
| 7879852 | Melanocortin receptor agonists The present invention relates to a compound of the following formula 1, pharmaceutically acceptable salt and isomer thereof effective as agonist of melanocortin receptor, and an agonistic composition of melanocortin receptor comprising the same as active ingredient.... | 02/01/2011 |
| 7858621 | Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention pro... | 12/28/2010 |
| 7851470 | Composition and methods for modulating a kinase cascade The invention relates to compounds and methods for modulating one or more components of a kinase cascade. ... | 12/14/2010 |
| 7838523 | Certain substituted amides, method of making, and method of use thereof At least one chemical entity chosen from compounds of Formula 1 and pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, prodrugs, and mixtures thereof is described herein. Pharmaceutical c... | 11/23/2010 |
| 7825115 | Cyclic urea compounds, preparation thereof and pharmaceutical use thereof as kinase inhibitors The disclosure relates to a cyclic urea compound of formula I: as defined herein, to the process for its preparation, pharmaceutical composition comprising it and its pharmaceutical use as an inhibitor on a protein kinase. ... | 11/02/2010 |
| 7812020 | Substituted pyridine derivatives The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders. ... | 10/12/2010 |
| 7812021 | Pyrrolidine aryl-ether as NK3 receptor antagonists The invention relates to a compound of general formula wherein Ar, R1, R2, R3, R4, n, o, p, s, X and are as def... | 10/12/2010 |
| 7807672 | Compounds that are ERK inhibitors Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a do... | 10/05/2010 |
| 7781435 | Imidazole compounds for the treatment of neurological disorders The present invention relates to compounds of Formula I wherein R1, R2, R3, R4, R6, R7 and A are as defined. Compounds of Formula I have activity inhibiting ... | 08/24/2010 |
| 7723332 | Aryl sulfonamides useful for modulation of the progesterone receptor In one embodiment, compounds of the following structure are described, wherein R1to R7are described herein. Also provided are methods for preparing these compounds and methods of contraception; treating ... | 05/25/2010 |
