Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
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| Number | Title | Issue Date |
| 8138177 | Benzimidazolone derivatives as CB2 receptor ligands This invention relates to compounds of the formula (I): or pharmaceutically acceptable salts thereof, wherein: A, B, R1, R2 and R3 are each as described herein, and compositions containing such compounds and the use of such compounds... | 03/20/2012 |
| 8097617 | Organic compounds New compounds of the Formula (I): for the treatment of non-insulin-dependent diabetes mellitus. ... | 01/17/2012 |
| 8058269 | Oxindole derivatives There is provided compounds of the formula wherein R6, V, W, X, Y, Q and n are as described. The compounds exhibit activity as anticancer agents. ... | 11/15/2011 |
| 8053431 | Pharmaceutical use of substituted amides The use of substituted amides for modulating the activity of 11-hydroxysteroid dehydrogenase type 1 (11HSD1) and the use of these compounds as pharmaceutical compositions, are described. Also a novel class of substituted amides, their use in therapy, pharmaceutical ... | 11/08/2011 |
| 8044045 | Indazole-carboxamide compounds as 5-HTreceptor agonists The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 recep... | 10/25/2011 |
| 7981886 | Antibiotics derivatives The invention relates to antibiotic derivatives of formula I wherein: A represents —O—, S, —C(═O)—, —C(═NOR6)—; Z—B represents NCH2CH2, NCOCH... | 07/19/2011 |
| 7964593 | Indolone-acetamide derivatives, processes for preparing them and their uses The present invention relates to indolone-acetamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as for the treatment of epilepsy, epileptogenesis, seizure disorders and convulsion. ... | 06/21/2011 |
| 7879844 | Heterocyclic janus kinase 3 inhibitors The present invention provides a compound of formula (I) having an excellent JAK3 inhibition activity and being useful as an active ingredient of an agent for treating and/or preventing various immune diseases including autoimmune diseases inflammatory diseases, and... | 02/01/2011 |
| 7879845 | Bicyclic sulfonamide derivatives which are L-CPT1 inhibitors The invention is concerned with novel heterobicyclic derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6, V, W, X and Y are as defined in the descripti... | 02/01/2011 |
| 7858616 | Indolinone derivatives substituted in the 6 position, their preparation and their use as medicaments The present invention relates to indolinone derivatives, substituted in the 6-position, of the formula in which R1 to R6 and X are as defined in Claim 1, to their tautomers, enantio... | 12/28/2010 |
| 7851467 | Carbamate compounds as 5-HTreceptor agonists The invention provides novel benzoimidazolone-carboxamide-derived carbamate 5-HT4 receptor agonist compounds of formula (I): wherein R1, R2, R3, R4, a, and b are define... | 12/14/2010 |
| 7795250 | Indole derivatives as antiviral agents The present invention relates to indole compounds of the formula (I): wherein R1, R2, R3, R4, A, E and X are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepat... | 09/14/2010 |
| 7732441 | Azabicycloalkane compounds This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification... | 06/08/2010 |
| 7723325 | 5-amido-indole-2-carboxamide derivatives The present invention relates to compounds of formula I wherein G and R1 to R5 and R12 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compou... | 05/25/2010 |
| 7713964 | Methods for treating asthmatic conditions This invention provides methods for treating in mammals asthma and asthmatic conditions using substituted indole compounds of the general formula: and pharmaceutically acceptable salt forms thereof, and methods for using th... | 05/11/2010 |
| 7605156 | Methods for the use of inhibitors of cytosolic phospholipase A2 This invention provides methods for the use of substituted indole compounds of the general formula: and pharmaceutically acceptable salt forms thereof. The invention provides methods for the use of the compounds as inhibito... | 10/20/2009 |
| 7534788 | Benzofuran and benzothiophene-2-carboxylic acid amide derivatives The present invention relates to compounds of formula I wherein X, A and R1 to R4 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful f... | 05/19/2009 |
| 7465726 | Substituted pyrrolo[2.3-B]pyridines Compounds represented by Formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, are inhibitors of least two of the Abl, Aurora-A, Blk, c-Raf, cSRC, Src, PRK2, FGFR3, Flt3, Lck, ... | 12/16/2008 |
| 7439238 | Antiparasitic artemisinin derivatives (endoperoxides) This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substitued derivatives of artemisinin, processes f... | 10/21/2008 |
| 7432255 | 1H-indol-5-yl-piperazin-1-yl-methanone derivatives The present invention relates to compounds of formula I and their pharmaceutically acceptable salts wherein in formula I is: wherein R1 to R4 are as defined in the description and claims. The compounds... | 10/07/2008 |
| 7432276 | ABCA1 elevating compounds The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The inve... | 10/07/2008 |
| 7423045 | ABCA1 elevating compounds The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The inve... | 09/09/2008 |
| 7402579 | Quinobenzoxazine analogs and compositions The present invention relates to quinobenzoxazines analogs having the general formula: and pharmaceutically acceptable salts, esters and prodrugs thereof; wherein A, U, W, X, Z, B, ... | 07/22/2008 |
| 7399760 | Pyrimidinedione derivatives Pyrimidinedione derivatives of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them are useful for the tre... | 07/15/2008 |
| 7384940 | Method of treating cancer using kinase inhibitors Described herein are methods for treating cancer and other disease conditions in individuals who have either developed a resistance to conventional tyrosine kinase inhibitor (TKI) therapy or who are non-responsive ab initio to conventional TKI therapy. In various em... | 06/10/2008 |
| 7371765 | Quinoline derivatives having VEGF inhibiting activity The invention relates to compounds of formula (I) wherein: either any one of G1, G2, G3, G4 and G5 is nitrogen and the other four are —CH—, or G1, G2, G3, G4 and G... | 05/13/2008 |
| 7361682 | Indole derivatives as H3 inverse agonists The present invention relates to compounds of formula I: wherein X, R1, R2, R3, R4 and R5 are as defined in the description and claims, and pharmaceutically acceptable ... | 04/22/2008 |
| 7358244 | Azabicycloalkane compounds This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, or a pharmaceutically acc... | 04/15/2008 |
| 7351704 | Indazole-carboxamide compounds as 5-HTreceptor agonists The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 recep... | 04/01/2008 |
| 7348426 | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates... | 03/25/2008 |
| 7342017 | 1,2,5-Thiadiazol-3-yl-piperazine therapeutic agents useful for treating pain, depression and anxiety A compound of formula: (wherein X, R1, R3, R4, and R5 are disclosed herein) or a pharmaceutically acceptable salt thereof (a “Thiadiazolylpiperazine Compound”), pharmaceutical... | 03/11/2008 |
| 7342022 | Compounds in the treatment of dementia related diseases, Alzheimer's Disease and conditions associated with glycogen synthase kinase-3 The present invention relates to new compounds of formula I wherein R1, R2, R3, n, m are defined as in claim 1, a process for their preparation and new intermediates used in the preparation thereof, pharmaceutical formulations contai... | 03/11/2008 |
| 7329655 | Nitrogenous heterocyclic compounds The present invention relates to nitrogen-containing heterocyclic compounds and pharmaceutically acceptable salts thereof which have inhibitory activity on the phosphorylation of kinases, which inhibits the activity of such kinases. The invention is also related to ... | 02/12/2008 |
| 7329752 | Carbamate compounds as 5-HTreceptor agonists The invention provides novel benzoimidazolone-carboxamide-derived carbamate 5-HT4 receptor agonist compounds of formula (I): wherein R1, R2, R3, R4, a, and b... | 02/12/2008 |
| 7326702 | Substituted quinobenzoxazine analogs The present invention relates to quinobenzoxazines analogs having the general formula: and pharmaceutically acceptable salts, esters and prodrugs thereof; wherein A, U, V, W, X and Z are substituents. | 02/05/2008 |
| 7320984 | Remedies or preventives for urinary frequency or urinary incontinence and morphinan derivatives having nitrogen-containing heterocyclic group The invention provides a morphinan derivative of the Formula (I): wherein R1 is methyl, cyclopropylmethyl or the like; R2 and R3 are hydroxy, methoxy, acetoxy or the like; both Y ... | 01/22/2008 |
| 7312212 | Aminopiperidine derivatives Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man. ... | 12/25/2007 |
| 7312209 | Acridone inhibitors of IMPDH enzyme Compounds having the formula (I), wherein R3 is selected from H, OH and NH2; R30 is selected from ═O and ═S; W is —C(═O)—, —S(═O)—, or —S(O)2—; or W... | 12/25/2007 |
| 7294629 | Quinazoline derivatives A compound of the formula (I) or a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, an optically active compound thereof, a racemate thereof or a diastereomer mixture thereof has a ... | 11/13/2007 |
| 7279493 | Therapeutic agents useful for treating pain A compound of formula: wherein A, Ar, R3, R6, and m are disclosed herein, or a pharmaceutically acceptable salt thereof (a “Cyanoiminopiperazine Compound”), compositions comprising an ef... | 10/09/2007 |