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| Number | Title | Issue Date |
| 7910580 | Enhancement of effectiveness of 5-Fluorouracil in treatment of tumor metastases and cancer Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof. ... | 03/22/2011 |
| 7371743 | Carboxylic acid amides, the preparation thereof and their use as medicaments The present invention relates to new substituted carboxylic acid amides of general formula wherein A, B and R1 to R5 are defined as in claim 1, the tautomers, the enantiomers, the diastereomers,... | 05/13/2008 |
| 7361653 | Pest control agent composition and method of using the same The present invention relates to a composition for noxious organisms-controlling agent having a synergistic effect and a method for using said composition, which comprises, as active ingredients thereof, one or more compounds selected from the phthalamide derivative... | 04/22/2008 |
| 7345039 | Enhancement of effectiveness of 5-fluorouracil in treatment of tumor metastases and cancer Tumor growth and metastases in cancer patients are inhibited by administration of a combination therapy including effective amounts of 5-Fluorouracil and a methylol transfer agent such as taurolidine, taurultam or mixtures thereof. ... | 03/18/2008 |
| 7230000 | Methods and compositions utilizing quinazolinones Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity ... | 06/12/2007 |
| 7217706 | Propanolamine derivatives This invention relates to new propanolamine derivatives or salts thereof represented by the following formula [I]: Wherein each symbol is as defined in the specification or salts thereof which have gut selective sympatho... | 05/15/2007 |
| 7214701 | Active substance combinations having insecticidal and acaricdal properties The invention relates to insecticidal mixtures for protecting plants against attack by pests comprising (a) compounds of the formula (I) ... | 05/08/2007 |
| 7195773 | Pesticidal composition A pesticidal composition comprising a pesticidally effective amount of at least one of a pyridic compound of the formula (I) or it salt and at least one of other pesticides: wherein Y is a haloalkyl group, m is 0 or 1, and Q is or a substituted or unsubstituted hete... | 03/27/2007 |
| 7026307 | Method for producing 1,3-disubstituted 2-nitroguanidines The present invention relates to a process for the preparation of compounds of the formula (I) by reacting compounds of the formula (II) in which ... | 04/11/2006 |
| 6683028 | Cyclic guanidine derivatives and their use as pesticides The invention relates to novel guanidine derivatives of the formula (I) ##STR1## in which A, R1, R2, R3 and Z are as defined in the description, to a process for their preparation and to their use for controlling animal ... | 01/27/2004 |
| 6495546 | Propanolamine derivatives Propanolamine derivatives represented by the following formula (I): ##STR1## These derivatives may be 댣 agonists and exert sympathomimetic, anti-ulcerous, anti-pancreatitis, lipolytic and anti-urinary incontinence and anti-pollakiuria ac... | 12/17/2002 |
| 6420361 | Soil pesticide A liquid soil pesticide composition containing tetrahydro-3,5-dimethyl-2H-1,3,5-thiadiazine-2-thione. The composition contains 1,3-dichloropropene as a first co-solvent and a second co-solvent selected from the group consisting of dimethyl sulfoxide and ... | 07/16/2002 |
| 6410042 | Plant protection products in the form of a granulate with controlled release of the active agent Crop protection granules based on the active substance tetrahydro-3,5-dimethyl-1,3,5-thiadiazine-2-thione and comprising an outer shell having a proportion by weight of from 0.1 to 50% by weight, based on the granules, of which at least 50% by weight cons... | 06/25/2002 |
| 6344453 | Insecticidal heterocyclic compounds Insecticidal heterocyclic compounds of the formula ##STR1## wherein A represents a five-membered or six-membered heteroaryl group containing one to three hetero atoms selected from the group consisting of S, O and N, said heteroaryl group being unsubstitu... | 02/05/2002 |
| 6319912 | Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides This invention relates to cyclic combination therapies utilizing, in combination with a progestin, an estrogen, or both, progesterone receptor antagonists of the general structure: ##STR1## wherein the substituents are as defined herein, or pharmaceutical... | 11/20/2001 |
| 6232309 | Insecticidal heterocyclic compounds Insecticidal heterocyclic compounds of the formula: ##STR1## wherein A represents a five-membered or six-membered heteroaryl group containing one to three hetero atoms selected from the group consisting of S, O and N, said heteroaryl group being unsubstit... | 05/15/2001 |
| 6054454 | Method of controlling fish parasites The present invention relates to the use of compounds of formula ##STR1## wherein A is an unsubstituted or mono- to tetrasubstituted, aromatic or non-aromatic, monocyclic or bicyclic heterocyclic radical, where one to two of the substituents of A can... | 04/25/2000 |
| 5977156 | Fungicidal pyrazoles Method for protecting plants against fungal or bacterial attack, which comprises applying a 1-phenyl-pyrazole or 1-(2-pyridyl)pyrazole.... | 11/02/1999 |
| 5972915 | Pesticide containing a synergistic combination of active ingredients A pesticide comprising an active ingredient combination consisting of a) tetrahydro-3,5-dimethyl-1,3,5-thiadiazine-2-thione of the formula ##STR1## and b) O-(O-ethyl-S-n-propylphosphoryl)-O-(N-methylcarbamoyl)pyrocatechol of the formula ##STR2## ... | 10/26/1999 |
| 5948799 | Method for improving morbidity and/or mortality This invention relates to a method for reducing morbidity and/or mortality in a mammal with congestive heart failure due to non-ischemic etiology comprising administering amlodipine or a pharmaceutically acceptable amlodipine acid addition salt, and, opti... | 09/07/1999 |
| 5948776 | Compositions and methods for treating bone deficit conditions Compounds containing two aromatic systems covalently linked through a linker containing one or more atoms, or "linker" defined as including a covalent bond per se so as to space the aromatic systems at a distance 1.5-15Å, are effective in treating condit... | 09/07/1999 |
| 5929114 | Arylthio compounds Arylthiol and dithiobisarylamide antibacterial and antiviral agents have the general formula ##STR1## where A is monocyclic or bicyclic aryl which can contain up to 3 heteroatoms selected from O, S, and N, R1 and R2 are substitu... | 07/27/1999 |
| 5885598 | Insect control compositions comprising entomopathogenic fungi Insecticidal compositions which have an active content of buprofezin (I) ##STR1## in combination with insect-pathogenic fungi.... | 03/23/1999 |
| 5753256 | Plaster for the treatment of nail mycoses The invention relates to a plaster for the treatment of nail mycoses, which s characterized by an antimycotically active substance, clotrimazole and bifonazole being excluded.... | 05/19/1998 |
| 5716629 | Synergistic blend of 1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane tetrahydro-3,5,-dimethyl-2h-1,3,5-thiadiazine-2-thione The invention is a composition for controlling microbiological growth which comprises a combination of 1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane and tetrahydro-3,5-dimethyl-2H-1,3,5-thiadiazine-2-thione. The invention has particular utility a... | 02/10/1998 |
| 5705497 | 3-alkoxycarbonyl-thiadiazinones 3-Alkoxycarbonyl thiadiazinones of the formula I ##STR1## and physiologically unobjectionable salts thereof, in which R1, R2, R3, R4, R5, Q and n have the meanings described herein, exhibit a pos... | 01/06/1998 |
| 5616579 | Anti-ulcer pyridyloxy derivatives, their preparation and uses Compounds of formula (I): ##STR1## [wherein: R1 is a cyclic amino group, or a dialkylamino group; R2 a group of formula --NHCHR3 R4 wherein R3 and R4 are each alkyl aryl or aralkyl, or... | 04/01/1997 |
| 5536715 | Combinations of anthelmintically active agents Pharmaceutical compositions comprising a compound of formula (I) and at least one other anthelmintically active compound, being an avermectin or a milbemycin, are useful in the treatment of helminthiasis. In formula (I): R is optionally substituted phenyl... | 07/16/1996 |
| 5496830 | Inhibition of hemoflagellates by camptothecin compounds Camptothecin compounds are effective inhibitors of hemoflagellate growth and are useful in treating leishmaniasis and trypanosomiasis in livestock, other domestic animals and humans.... | 03/05/1996 |
| 5077314 | Agricultural gel-forming compositions A method is disclosed for the containment and controlled release of and the substantial reduction of the leaching from the site of application of agricultural chemicals. In the disclosed method, the agricultural chemicals are applied to the soil dispersed... | 12/31/1991 |
| 5063215 | Biocidal compositions and use thereof containing a synergistic mixture of n-tributyl tetradecyl phosphonium chloride and 3,5-D-thiadiazine thione A bactericidal composition and method for inhibiting and controlling the growth of the capsulated, facultative bacterium, Klebsiella pneumoniae, are disclosed. The composition comprises an amount, effective for the intended purpose of n-tributyl tetradecy... | 11/05/1991 |
| 5021412 | Thiadiazines, and insecticidal and acaricidal preparations Novel tetrahydro-1,3,5-thiadiazin-4-ones of the following general formula (I) or their salts which are useful as an insecticidal and acaricidal agent. ##STR1## In the formula, each of R1 and R2 represents a halogen atom or a ... | 06/04/1991 |
| 4994476 | Dihydropyridin-3,5-dicarboxylates incorporating aryloxypropanolamine moieties A series of compounds useful in treating cardiovascular disorders due to the combined expression of both ଲ-block and calcium-block activity by these agents. This useful combination of actions is effected by a novel combination of structural subunits... | 02/19/1991 |
| 4935447 | Agricultural gel-forming compositions A method is disclosed for the containment and controlled release of and the substantial reduction of the leaching from the site of application of agricultural chemicals. In the disclosed method, the agricultural chemicals are applied to the soil dispersed... | 06/19/1990 |
| 4735942 | [[4 -[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]-methyl]-1H- imidazoles and 1H-1,2,4-triazoles having antimicrobial properties Substituted [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3 dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having antimicrobial properties and being particularly useful in the treatment of vaginal candidosis.... | 04/05/1988 |
| 4719209 | Antiatherosclerotic agent compositions 3,5-Dimethyl-4,6-diphenyl-tetrahydro-2H-1,3,5-thiadiazine-2-thione having the formula: ##STR1## for use as an active therapeutic agent.... | 01/12/1988 |
| 4639444 | 3,5-dialkyl-4,6-diaryl-tetrahydro-2H-13,5-thiadiazine-2-thione derivative, process for its production and antihyperlipidemic agent containing it A compound of the formula: ##STR1## wherein R is methyl or ethyl, X is hydrogen (provided R is ethyl), lower alkyl, lower alkoxy, lower alkylthio, fluorine, bromine, phenoxy or substituted phenoxy, Xm is methylenedioxy or --CH.dbd.CH-... | 01/27/1987 |
| 4624950 | Method for treating atherosclerosis hyperlipidema, lipid deposition on arterial walls, or raising the ratio of high density lipoprotein cholesterol to total cholesterol in serum 3,5-Dimethyl-4,6-diphenyl-tetrahydro-2H-1,3,5-thiadiazine-2-thione having the formula: ##STR1## as an antiatherosclerotic agent.... | 11/25/1986 |
| 4568672 | 3,6-Disubstituted 2-thioxo-1,3,5-thiadiazin-4-ones 3,6-Disubstituted 2-thioxo-1,3,5-thiadiazin-4-ones of the formula ##STR1## in which R1 represents hydrogen; alkyl which is optionally monosubstituted or polysubstituted by identical or different substituents; alkenyl which is optionally mo... | 02/04/1986 |
| 4452795 | 5-Phenoxyphenyl-tetrahydro-1,3,5-thiadiazin-4-ones The invention relates to novel substituted 5-phenoxyphenyl-tetrahydro-1,3,5-thiadiazin-4-ones of the formula ##STR1## wherein R1 is hydrogen, halogen, C1 -C4 -alkyl, trifluoromethyl, methoxy, ethoxy, benzyl, phenoxy, ... | 06/05/1984 |
