Celebrity Inventors
Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 7915252 | Sulfonyl compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 Sulfonyl derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dysli... | 03/29/2011 |
| 7820648 | Pyrimidine derivatives for the treatment of abnormal cell growth The present invention relates to a compound of the formula 1 or a pharmaceutically acceptable salt thereof, wherein Ar is a group of formula and R1, R2, R | 10/26/2010 |
| 7342043 | Medicinal compositions improving brain function and method for improving brain function An alkyl ether derivative represented by the formula: wherein R1, R2, R3, R4, m and n are as defined in the specification, or salts thereof exhibits synergistically improved anti-... | 03/11/2008 |
| 7300928 | Benzimidazolidinone derivatives as muscarinic agents Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes, pharmaceutical compositions comprising the s... | 11/27/2007 |
| 7294628 | Piperazinylacylpiperidine derivatives, their preparation and therapeutic use thereof The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; R1 represents a halogen at... | 11/13/2007 |
| 7176212 | 2,4-diamino pyrimidine compounds having anti-cell proliferative activity A pyrimidine derivative of formula (I) wherein, for example, R1 is hydrogen, (1–6C)alkyl, (3–5C)alkenyl or (3–5C)alkynyl; Q1 and Q2 are independently selected from phenyl, naphthyl, indanyl and 1,2,3,4-tetrahydronaphthyl; and o... | 02/13/2007 |
| 7166588 | Derivatives and analogs of galanthamine New compounds of general formula I ... | 01/23/2007 |
| 7153964 | Pyrimidine compounds Pyrimidine derivatives of formula (I) wherein: Qh1 and Q2 are independently selected from aryl or carbon linked heteroaryl optionally substituted as defined within; and one of Q1 and Q2 or both Q1 and Q2 | 12/26/2006 |
| RE39300 | Inhibiting the development of tolerance to and/or dependence on an addictive substance Nontoxic substances that block the N-methyl-D-aspartate (NMDA) receptor, e.g., a morphinan such as dextromethorphan or dextrorphan, or that block a major intracellular consequence of NMDA-receptor activation, e.g., a ganglioside such as GM1 or GT1b | 09/19/2006 |
| 7101916 | Exo-S-mecamylamine formulation and use in treatment A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in combination with a pharmaceutically acceptable carrier. Preferably the amount is... | 09/05/2006 |
| 7094786 | Method of treating nausea, vomiting, retching or any combination thereof Methods are disclosed for the treatment of nausea and vomiting in a patient suffering therefrom comprising administering 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine. ... | 08/22/2006 |
| 7067522 | 2,4,DI (hetero-) arylamino (-oxy)-5-substituted pyrimidines as antineoplastic agents Pyrimidine derivatives of formula (I) wherein Q1, Q2, G and R1 are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compos... | 06/27/2006 |
| 7067515 | Quinuclidines-substituted-multi-cyclic-heteroaryls for the treatment of disease The invention provides compounds of Formula I: where in W is These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or... | 06/27/2006 |
| 7030245 | Antidepressant azahetorocyclylmethyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenathrene Compounds of the formula useful for the treatment of such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disord... | 04/18/2006 |
| 7001900 | Azabicyclic compounds for the treatment of disease The invention provides compounds of Formula I: wherein Azabicyclo is W is a six-membered heterocyclic ring system having 1–2 nitrogen atoms or a 10-membered bicyclic-six-... | 02/21/2006 |
| 6969714 | Imidazolo-5-YL-2-anilino-pyrimidines as agents for the inhibition of the cell proliferation Compounds of the formula (I): wherein R1, R2, R3, R4, R5, R6, p, q, and n are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described ar... | 11/29/2005 |
| 6951868 | Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease The invention provides compounds of Formula I: wherein Azabicyclo is any of: These compounds may be in the form of pharmaceutical salts or compositions, and racemic mixtu... | 10/04/2005 |
| 6951849 | Benzimidazolidinone derivatives as muscarinic agents Benzimidazolidinone derivative compounds, which increase acetylcholine signaling or effect in the brain, and highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes, pharmaceutical compositions comprising the s... | 10/04/2005 |
| 6949539 | Admantane derivatives The invention provides compounds of general formula (I) in which m, A, R1 and Ar have the meanings defined in the specification; a process for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compo... | 09/27/2005 |
| 6930109 | Antidepressant azaheterocyclyl methyl derivatives of 7,8-dihydro-6H-5-oxa-1-aza-phenanthrene Compounds of the formula useful for the treatment of such as depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disor... | 08/16/2005 |
| 6911543 | Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease The invention provides compounds of Formula I: wherein Azabicyclo is These compounds may be in the form of pharmaceutical salts or co... | 06/28/2005 |
| 6908920 | Pyrimidine derivatives Compounds of formula (I), wherein R1, p, R2, q, R3 and R4 are defined within, and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and th... | 06/21/2005 |
| 6906065 | 4-Amino-5-cyano-2-anilino-pyrimidine derivatives and their use as inhibitors of cell-cycle kinases Compounds of formula (I) wherein: R1 is halo, nitro, cyano, hydroxy, amino, carboxy, carbamoyl, mercapto, C1-6alkyl, C2-6alkenyl or C2-6alkynyl; p is 0-4; wherein the values of R1 may be the same or different; R... | 06/14/2005 |
| 6869946 | Substituted azabicyclic moieties for the treatment of disease The invention provides compounds of Formula I: wherein m1 is 0 or 1; m2 is 1 or 2; R1 is —H, alkyl, halogenated alkyl, subst... | 03/22/2005 |
| 6812234 | Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity The present invention is directed to compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 | 11/02/2004 |
| 6784194 | Therapeutic use of a thienylcyclohexylamine derivative A method of inhibiting effects of exogenous neurotoxic or neurotoxinic products in warm-blooded animals comprising administering to warm-blooded animals before exposure to said products an inhibitorily effective amount of reversible cholinesterase inhibitor selected... | 08/31/2004 |
| 6649605 | Treatment of tension-type headaches with NMDA receptor antagonists NMDA receptor antagonists, especially mirtazapine, can be used to treat tension-type headaches.... | 11/18/2003 |
| 6465491 | 6-phenylpyridyl-2-amine derivatives The present invention relates to certain 6-phenyl-pyridin-2-ylamine derivatives that exhibit activity as nitric oxide synthase (NOS) inhibitors, to pharmaceutical compositions containing them and to their use in the treatment and prevention of central ner... | 10/15/2002 |
| 6462065 | Use of 5-HT3 receptor antagonists for treating musculoeskeletal diseases The present invention relates to a new use for compounds having 5-HT3 (serotonin M) receptor antagonist activity, especially tropisetron, for the manufacture of a pharmaceutical composition for the treatment of a non-inflammatory local disease ... | 10/08/2002 |
| 6348456 | Method of treating chemical dependency in mammals and a composition therefor An essentially pure noribogaine compound having the formula: ##STR1## wherein R is hydrogen or a hydrolyzable group of the formula: ##STR2## wherein X is an unsubstituted C1 -C12 group or a C1 -C12 group substit... | 02/19/2002 |
| 6235747 | 6-phenyl-pyridin-2-ylamine derivatives The present invention relates to certain 6-phenyl-pyridin-2-ylamine derivatives that exhibit activity as nitric oxide synthase (NOS) inhibitors, to pharmaceutical compositions containing them and to their use in the treatment and prevention of central ner... | 05/22/2001 |
| 6103713 | Therapeutic treatment for autoimmune diseases Methods for inhibiting activation and/or proliferation of T cells and B cells and for treating autoimmune diseases and/or disease manifestations are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-[N, N'-1,1'-((2"-ethoxy)-3... | 08/15/2000 |
| 6071900 | Heterocyclic compounds and their use The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nerv... | 06/06/2000 |
| 6051575 | Piperazino derivatives as neurokinin antagonists The invention relates to compounds of the formula ##STR1## wherein Z, Rc, y, m, u, Ar2, n, X, Rc', I and Ar2 are as described herein. These compounds are neurokinin antagonists. These compounds are useful i... | 04/18/2000 |
| 6015813 | Heterocyclic compounds and their preparation and use The present invention relates to therapeutically active azabicyclic compounds of formula I ##STR1## wherein X, R1, R2, R3, Ar, m and n are defined in the description, a method of preparing the same and to pharmaceutic... | 01/18/2000 |
| 5968929 | Piperazino derivatives as neurokinin antagonists The invention relates to compounds of the formula ##STR1## wherein Z, Rc, y, m, u, Ar2, n, X, Rc', l and Ar2 are as described herein. These compounds are neurokinin antagonists. These compounds are useful i... | 10/19/1999 |
| 5888999 | Method for treating anxiety with muscarinic cholinergic receptor agonists The present invention relates a method for treating anxiety using azacyclic and azabicyclic pyrazine compounds.... | 03/30/1999 |
| 5763457 | Method for treating anxiety The present invention relates a method for treating anxiety using azacyclic and azabicyclic oxadiazole compounds.... | 06/09/1998 |
| 5710167 | Hydroxamic acid derivatives with tricyclic substitution for treating degenerative joint diseases The invention provides hydroxamic acid derivatives of the general formula ##STR1## wherein R1 represents cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl; R2 represents a saturated 5- to 8-membered monocyclic or bridged N-hete... | 01/20/1998 |
| 5686448 | Treatment of virus infections with ganglionic blocking agents A method for preventing or treating infection or disease in a mammal caused by a virus, such as herpes simplex virus type 1 and 2. A ganglionic blocking agent, such as tetraethylammonium ion or hexamethonium ions, is administered to the mammal in an effec... | 11/11/1997 |
