Bizarre Patents
A simulation environment for the sport of boxing utilizing a robotic machine interface system which carries a person.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8148364 | Substituted bicyclic pyrimidone derivatives A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: Wherein Y, Z, R1, R2, R3, R4, R5, R6, R7, n, m, and o are as described herein. The invention relates also to a... | 04/03/2012 |
| 8119628 | Pyrrolidine fused indolobenzadiazepine HCV NS5B inhibitors The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. | 02/21/2012 |
| 8076324 | Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them The present invention relates to di(hetero)arylcyclohexane derivatives of the formula I, in which Ar1, Ar2, R1 and R2 have the meanings indicated in the claims. The compounds of t... | 12/13/2011 |
| 8063040 | Triazabenzo[E]azulene derivatives for the treatment of tumors Novel triazabenzo[e]azulene derivatives of the formula, (I) in which R1, R2 and R3 have the meanings indicated in Claim 1, are inhibitors of TGF-beta receptor kinase and can be employed, inter alia, for the treatment of tumors... | 11/22/2011 |
| 8022061 | N-aryl pyrazole compounds, compositions, and methods for their use Compounds having formula I: where A1, A2, L, V, W, R1, R2, R3, R4 and R5 are as described herein, compositions thereof, and their use for the trea... | 09/20/2011 |
| 7754709 | Tetracyclic thiophenepyrimidinone compounds as inhibitors of 17β hydroxysteroid dehydrogenase compounds Thiopheneprymidinone compounds useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder, preferably a steroid hormone dependent disease or disorder requiring the inhibition of a 17β-hydroxysteroid dehydrogenas... | 07/13/2010 |
| 7754710 | Noribogaine in the treatment of pain and drug addiction The present invention is directed to methods of treating patients for pain by administering noribogaine. Noribogaine may also be used to treat patients for the symptoms associated with withdrawal from drug dependency. In the latter case, the noribogaine treatment sh... | 07/13/2010 |
| 7732438 | CGRP receptor antagonists Compounds of Formula (I) and Formula (II) (where variables R1, R2, R4, A, B, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is invo... | 06/08/2010 |
| 7732437 | Use of anti-histaminics for acute reduction of elevated intracranial pressure The invention concerns a novel histamine receptor antagonist and the use of an histamine receptor antagonist for the reduction of intracranial pressure (ICP), in particular for the prevention and treatment of elevated intracranial pressure and/or secondary ischaemid... | 06/08/2010 |
| 7713959 | Compositions of an anticonvulsant and mirtazapine to prevent weight gain Disclosed are pharmaceutical compositions comprising mirtazapine and an anticonvulsant drug. Also disclosed are methods of preventing weight gain associated with the administration of mirtazapine comprising identifying a patient to whom mirtazapine is to be administ... | 05/11/2010 |
| 7538104 | Photoactivable nitrogen bases Compounds of the formula I R7″N—R6 RS—C,N—R4 H C, R′/I R, 3 R 2 (I) in which R, is an aromatic or heteroaromatic radical which is capable of absorbing light in the wave-length range from 200 nm to 650 nm and which is unsubstituted or substituted one or mor... | 05/26/2009 |
| 7476662 | Substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine The invention concerns novel substituted tetracyclic imidazole derivatives useful for the treatment of elevated intracranial pressure (ICP) and/or secondary ischaemia, in particular caused by brain injury, more in particular caused by traumatic (TBI) and non-traumat... | 01/13/2009 |
| 7414045 | Substituted pyrimido[1,2-a]azepines useful as HIV integrase inhibitors Tetrahydro-4H-pyrido[1,2-a]pyrimidines and related compounds of Formula (A): are described as inhibitors of HIV integrase and inhibitors of HIV replication, wherein n is an integer equal to zero, 1, 2 or 3, and R1, R3, R4, R12 | 08/19/2008 |
| 7390798 | Carboxamide spirolactam CGRP receptor antagonists The present invention is directed to compounds of Formula I: I (where variables A1, A2, B, J, K, m, n, R4, R5a, R5b and R5c are as defined herein) useful as antagonists of CGRP receptors and useful in... | 06/24/2008 |
| 7378082 | Method for treating allergic rhinitis without adverse effects The present invention is directed to a method for treating allergic rhinitis without causing an adverse effect of bitter taste. The method comprises administering to a patient an aqueous pharmaceutical formulation comprising 0.1-0.15% (w/v) of epinastine or an acid ... | 05/27/2008 |
| 7371220 | System and method for real-time apnea/hypopnea detection using an implantable medical system Techniques are provided for detecting the onset of an episode of apnea/hypopnea substantially in real-time. A moving threshold is generated based on recent respiration cycles and differences are accumulated between amplitudes of new respiration cycles and the moving... | 05/13/2008 |
| 7361146 | System and method for detecting abnormal respiration via respiratory parameters derived from intracardiac electrogram signals Techniques are provided for tracking patient respiration based upon intracardiac electrogram (IEGM) signals or other electrical cardiac signals. Briefly, respiration patterns are detected based upon cycle-to-cycle changes in morphological features associated with in... | 04/22/2008 |
| 7268127 | Azaindoles having serotonin receptor affinity Described herein are compounds with affinity for the 5-HT6 receptor, which have the general formula I: Wherein A, B, D, E, R1 to R3 and n are described herein. Also described is t... | 09/11/2007 |
| 7262190 | Benzothiazine and benzothiadiazine compounds The invention relates to compounds of formula (I): wherein: R1 represents hydrogen, alkyl or cycloalkyl, R2 represents hydrogen, halogen or hydroxy, A ... | 08/28/2007 |
| 7256363 | Intermediate switch actuator array A switch actuator assembly is provided comprising a circuit board housing including an upper housing and a lower housing forming a board compartment. A circuit board assembly, mounted within the board compartment, includes a switch element. A button assembly, positi... | 08/14/2007 |
| 7247623 | Method of treating dry eye disease with non-drying antihistamines A method and preparation for reducing dry eye symptoms and promoting tear secretion in a subject in need of such treatment is disclosed. The method comprises administering to the eyes of the subject a non-drying antihistamine compound, such as epinastine hydrochlori... | 07/24/2007 |
| 7220737 | Noribogaine in the treatment of pain and drug addiction The present invention is directed to methods of treating patients for pain by administering noribogaine. Noribogaine may also be used to treat patients for the symptoms associated with withdrawal from drug dependency. In the latter case, the noribogaine treatment sh... | 05/22/2007 |
| 7214691 | 2-substituted benzimidazole derivatives as selective melanin concentrating hormone receptor antagonists for the treatment of obesity and related disorders The present invention discloses compounds of formula I wherein Ar, X, R1 and R11 are herein defined, said compounds being novel antagonists for melanin-concentrating hormone (MCH), as well a... | 05/08/2007 |
| 7202238 | Diazabicyclo alkane derivatives with NKantagonistic activity The present invention relates to a group of unique diazabicyclo alkane derivatives having interesting neurokinin-NK1 receptor antagonistic activity represented by the general formula (1) wherein: R1 represents phenyl, 2-indolyl, 3-indolyl, 3-in... | 04/10/2007 |
| 7179229 | System and method for apnea detection using blood pressure detected via an implantable medical system Techniques are provided for detecting non-obstructive forms of apnea within a patient using an implantable medical system based on changes in blood pressure. The implantable system monitors for any substantially uniform decease in diastolic blood pressure over a ser... | 02/20/2007 |
| 7173022 | Bicyclic heterocycles as HIV integrase inhibitors The invention encompasses a series cyclic bicyclic heterocyclic compounds of Formula I which are inhibitors of HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also ... | 02/06/2007 |
| 7105663 | Derivatives of pyrimido[6,1-a]isoquinolin-4-one Compounds of general formula (I) wherein each of R1 and R2 independently represents a C1-6 alkyl or C2-7 acyl group; R5 represents a hydrogen atom or a C1-3 alkyl, C2-3 alkenyl or C2-3... | 09/12/2006 |
| 7094207 | System and method for diagnosing and tracking congestive heart failure based on the periodicity of cheyne-stokes respiration using an implantable medical device Techniques are provided for distinguishing Cheyne-Stokes Respiration (CSR) caused by central sleep apnea (CSA) from CSR caused by congestive heart failure (CHF) and for evaluating the severity of CHF, if present, based up CSR. A time period associated with the CSR i... | 08/22/2006 |
| 7086397 | Patient usable emergency medical kit The invention provides an emergency medical kit for use immediately upon the onset of symptoms of an attack of a vascular disease such as a heart attack or a stroke. The emergency medical kit at least includes breathable oxygen in a light weight container and may in... | 08/08/2006 |
| 7081455 | Substituted heterocycle fused gamma-carbolines The present invention is directed to methods of treating addictive behavior and sleep disorders by administering compounds represented by structural Formula (I) or pharmaceutically acceptable salt forms thereof, ... | 07/25/2006 |
| 7070568 | System and method for diagnosing and tracking congestive heart failure based on the periodicity of Cheyne-Stokes Respiration using an implantable medical device Techniques are provided for distinguishing Cheyne-Stokes Respiration (CSR) caused by central sleep apnea (CSA) from CSR caused by congestive heart failure (CHF) and for evaluating the severity of CHF, if present, based up CSR. A time period associated with the CSR i... | 07/04/2006 |
| 7030108 | Combating Parkinson's disease-related movement disorder A method of combating movement disorder is disclosed in a patient with Parkinson's disease comprising administering an effective amount of mirtazapine, a receptor antagonist for 5HT2/3 and α2 receptors. ... | 04/18/2006 |
| 6953791 | Dipeptide derivatives This invention is directed to compounds of the formula and the pharmaceutically-acceptable salts thereof, where the substituents are as defined in the Specification, which are growth hormone secretogogues and which inc... | 10/11/2005 |
| 6939854 | Peptide inhibitors of hepatitis C virus NS3 protease This invention relates to a novel class of peptides having the Formula (I): which are useful as serine protease inhibitors, and more particularly as Hepatitis C virus (HCV) NS3 protease inhibitors. This invention also ... | 09/06/2005 |
| 6933293 | Use of mirtazapine for the treatment of sleep disorders The invention relates to the use of mirtazapine for the preparation of a medicine for a new method of treatment of a sleep disorder in a subject, which treatment comprises the administration of mirtazapine with a unit treatment dose comprising between 0.1 and 5 mg m... | 08/23/2005 |
| 6906060 | Substituted hexahydropyrrolo[1,2-a]pyrazines, octahydropyrido[1,2-a]-pyrazines and decahydropyrazino[1,2-a]azepines Novel substituted hexahydropyrrolo[1,2-a]pyrazines, octahydropyrido[1,2-a]-pyrazines and decahydropyrazino[1,2-a]azepines, use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, and a method of treatment employin... | 06/14/2005 |
| 6849619 | Substituted pyridoindoles as serotonin agonists and antagonists The present invention is directed to certain novel compounds represented by structural Formula (I) or pharmaceutically acceptable salt forms thereof, wherein R1, R5, R6, R7, ... | 02/01/2005 |
| 6835728 | Drug combination for the treatment of depression and related disorders comprising mirtazapine The invention relates to a combination comprising an amount of mirtazapine, or a pharmaceutically acceptable salt or solvate thereof, and an amount of gepirone, or a pharmaceutically acceptable salt or solvate thereof, optionally in association with one or more phar... | 12/28/2004 |
| 6794382 | Benzimidazole derivatives, preparation and therapeutic use thereof The invention relates to benzimidazole derivatives of general formula in which X represents a nitrogen atom or a carbon atom; and when X represents a nitrogen atom: R3 represents a hydrogen atom or a... | 09/21/2004 |
| 6727242 | Pharmacological treatment for sleep apnea The present invention relates generally to pharmacological methods for the prevention of amelioration of sleep-related breathing disorders via administration of agents or combinations of agents that possess serotonin-related pharmacological activity. ... | 04/27/2004 |
