Bizarre Patents
A haircutting appliance comprises an enclosed housing having a hollow handle connecting the housing to a vacuum source to carry away cut hairs from a subject's head.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8188069 | Azepine derivatives as gamma-secretase inhibitors Compounds of formula (I), pharmaceutical compositions comprising them, and methods for their use are described. ... | 05/29/2012 |
| 8076323 | Anti-inflammatory agents The invention provides compounds, pharmaceutical compositions and uses of compounds and salts thereof of general formula (I), for the preparation of a medicament for treatment of an inflammatory disorder, but excluding (S)-... | 12/13/2011 |
| 8063039 | 3-aminopyrrolidone derivatives A method for treating pain, migraine, inflammation, gastrointestinal tract disorders, disorders of the genito-urinary tract, ophthalmic diseases or obesity in a subject, the method including administering to the subject an effective amount of a compound of a general... | 11/22/2011 |
| 7803794 | Anti-inflammatory agents The invention provides compounds, pharmaceutical compositions and uses of compounds and salts thereof of general formula (I), for the preparation of a medicament for treatment of an inflammatory disorder, but excluding (S)-3-(r-methylcyclohexyl-carbonylamino)-caprol... | 09/28/2010 |
| 7803793 | Heterocyclic derived metalloprotease inhibitors This invention provides novel heterocyclic derived matrix metalloprotease inhibitors of the formula: and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing matrix metallop... | 09/28/2010 |
| 7767664 | Plant growth regulation The present invention relates to a new class of plant growth regulators. In particular, the invention relates to fused azepinone derivative of general formula (I) or an agriculturally acceptable salt thereof wherein X is CO2R2 or H; Y is OH; NH... | 08/03/2010 |
| 7691845 | Anti-inflammatory agents The invention provides compounds, compositions and uses of compounds of general formula (I) or (I′), or pharmaceutically acceptable salts thereof, which are 3-aminocaprolactam derivatives, for the preparation of a medicament intended to treat an inflammatory disor... | 04/06/2010 |
| 7691846 | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4-P-M-M4 I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle ... | 04/06/2010 |
| 7585855 | Bengamides with a substituted caprolactam cycle, method for the preparation thereof, compositions containing them and use thereof The invention relates to the preparation of substituted caprolactams, a method for the preparation thereof, compositions containing them and the use thereof as a medicament, particularly as anticancer agents. ... | 09/08/2009 |
| 7501406 | Fluoro substituted 2-oxo-azepan derivatives The invention relates to compounds of general formula wherein R1, R2, R3/R3′, R4/R4′ and R5/R5′ | 03/10/2009 |
| 7378410 | Substituted lactams and their use as anti-cancer agents This invention relates to certain substituted lactam compounds of the formula (I), particularly caprolactam compounds, which are useful for the treatment of cancer ... | 05/27/2008 |
| 7361648 | Heterocyclylakylamines as muscarinic receptor antagonists This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula I: wherein X, Y, and Z are O, S or NR5, and the other substituents are as defined... | 04/22/2008 |
| 7354914 | Lactams substituted by cyclic succinates as inhibitors of Aβ protein production This invention relates to novel lactams having the Formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifica... | 04/08/2008 |
| 7342007 | Lactams and uses thereof This invention relates to novel compounds having formula (I) to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit secretase and thereby inhibit the production of amyloid β protein, thereby acting to prevent the formation o... | 03/11/2008 |
| 7326698 | Prostaglandin analogs Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof is disclosed herein. A, X, J, and E are as described herein. These compounds are useful for treating diseases. ... | 02/05/2008 |
| 7304048 | Indole-type derivatives as inhibitors of p38 kinase The invention is directed to methods to inhibit p38-α kinase using compounds containing an aromatic system coupled through a 7-membered heterocycle to an indole-type system. ... | 12/04/2007 |
| 7304049 | Succinoylaminobenzodiazepines as inhibitors of Aβ protein production This invention relates to novel lactams having the formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, mor... | 12/04/2007 |
| 7294622 | Lactams and uses thereof Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid β protein production and neurological disorders such as Alzheimer's disease. These compounds inhibit... | 11/13/2007 |
| 7279582 | Retroviral protease inhibiting compounds A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed. ... | 10/09/2007 |
| 7253158 | Sulfonamides The invention relates to compounds of the general formula in which R1, R2, R3, R4, R2′, R3′, R4′, R5, and X is —CHR— are as defined in t... | 08/07/2007 |
| 7208488 | N-substituted benzene sulfonamides Disclosed are N-substituted benzenesulfonamides for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. In Formula (I), R1, R2, R3, R4, R | 04/24/2007 |
| 7205324 | Inhibitors of IMPDH enzyme The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5′-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as tr... | 04/17/2007 |
| 7160880 | Short-acting benzodiazepines The present invention provides a compound of formula (I): wherein all variables are as defined herein, pharmaceutical formulations containing the same, processes for preparing the same and their use therapy. ... | 01/09/2007 |
| 7153846 | Bengamide derivatives, process for preparing them, and their use The present invention relates to bengamide derivatives which are formed, during fermentation, by the microorganism Myxococcus virescens ST200611 (DSM 15898), to their use for treating cancer diseases, to pharmaceuticals which comprise bengamide derivatives, t... | 12/26/2006 |
| 7141561 | Substituted diaryl heterocycles, process for their preparation and their use as medicaments This invention discloses and claims diary heterocycles of formula (I) and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, and methods of using said compounds of formula (I) for the t... | 11/28/2006 |
| 7119188 | N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor This invention relates to isolated or recombinant N-carbobenzyloxy-deprotecting enzyme polypeptides, and variants and fragments thereof, that catalyze the removal of carbobenzyloxy from carbobenzyloxy-protected amino acids and alcohols. Also related are isolated nuc... | 10/10/2006 |
| 7109233 | Protease inhibitors This invention relates in general to certain substituted substituted 1,1,4-1l6-trioxo[1,2]thiazepan-4-ylamides of formula I as defined herein which are protease inhibitors. ... | 09/19/2006 |
| 7091200 | Quinazolone derivatives as alpha 1A/B adrenergic receptor antagonists This invention relates to compounds which are generally alpha-1A/B adrenoceptor antagonists and which are represented by Formula I: wherein Z is —C(O)— or —S(O)2—, X is... | 08/15/2006 |
| 7087596 | 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders This invention relates to new 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives of formula (1) having anticonvulsant activity which are useful as therapeutic agents for the treatment or prevention of epilepsy and other neurological disorders. The inven... | 08/08/2006 |
| 7034033 | Substituted quinazolinone compounds A variety of low molecular weight, guanidino-containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases. The compounds have the structure IA, IB, or IC where the values of the variable are defi... | 04/25/2006 |
| 7026358 | Oral general anesthetics and metabolitically resistant anticonvulsants The present invention is directed to novel themisone derivative compounds that have been modified to prevent the formation of the toxic metabolite, 2-phenyl-acrylamide. Compositions comprising such derivative compounds have activity as anesthetics and as neuroprotec... | 04/11/2006 |
| 7022844 | Amide-based compounds, production, recovery, purification and uses thereof Methods are disclosed of producing and purifying at least one amide. In accordance with one of the methods disclosed herein, the at least one amide is produced by providing an organic liquid comprising at least one oxime, providing at least one catalyst, adding the ... | 04/04/2006 |
| 7001899 | Interleukin converting enzyme inhibitors The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula: wherein each X is independently selected from: i) —C(W)2... | 02/21/2006 |
| 6992103 | Benzamide derivatives, processes for their preparation, and their pharmaceutical use The present invention relates to novel hydroxyethylene compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevat... | 01/31/2006 |
| 6958329 | Lactams substituted by cyclic succinates as inhibitors of A-β protein production This invention relates to novel lactams having the Formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more spec... | 10/25/2005 |
| 6953788 | 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase The present invention relates to certain novel 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase. Pharmaceutical compositions containing said compounds as well as methods of treating various disease state... | 10/11/2005 |
| 6951862 | Calcium channel blockers comprising two benzhydril moieties Certain piperazine substituted compounds are described which are useful in altering calcium channel activity. ... | 10/04/2005 |
| 6943168 | Calcium channel inhibitors comprising benzhydril spaced from piperazine Certain piperazine substituted compounds are described which are useful in altering calcium channel activity. ... | 09/13/2005 |
| 6921759 | Aza- and polyaza-naphthalenyl carboxamides useful as HIV integrase inhibitors Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described. These compounds are inhibitors of HIV integrase and inhibitors of HIV replication, and are useful in the prevention... | 07/26/2005 |
| 6906056 | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release an... | 06/14/2005 |
