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Pneumatic Shoe Lacing Apparatus
This invention provides a pneumatic shoe lacing apparatus for the pneumatic lacing of shoe.
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| Number | Title | Issue Date |
| 8030281 | Methods and apparatus for creating particle derivatives of HDL with reduced lipid content The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL. These derivatives of HDL are particles with reduced lipid content, particularly reduced cholesterol content.... | 10/04/2011 |
| 7781406 | Production and use of the methotrexate-albumin conjugate as an immunosuppressive agent in GVHD A method for modulating a transplantation-associated immune response in a subject is disclosed. The method comprises administering to the subject an effective amount of a conjugate comprising a carboxyl group-containing organic compound and albumin, wherein the carb... | 08/24/2010 |
| 7759315 | Treatment of inflammatory conditions of the intestine A method for the treatment and/or prophylaxis of an inflammatory condition of the intestine of a patient, comprises parenteral administration to the patient of an effective amount of high density lipoprotein (HDL). ... | 07/20/2010 |
| 7704958 | Methods and compositions for inhibiting apoptosis using serine protease inhibitors The instant invention provides a method of treating an animal suffering a disease characterized by excessive apoptosis by administering a therapeutically effective amount of at least one serine protease inhibitor and thereafter monitoring a decrease in apoptosis. Th... | 04/27/2010 |
| RE41288 | Metabolic intervention with GLP-1 or its biologically active analogues to improve the function of the ischemic and reperfused brain It has now been discovered that GLP-1 treatment after acute stroke or hemorrhage, preferably intravenous administration, can be an ideal treatment because it provides a means for optimizing insulin secretion, increasing brain anabolism, enhancing insulin effectivene... | 04/27/2010 |
| 7696176 | Blood replacement product A composition comprising Human Serum Albumin and an Amino Acid Solution, a method of making the same, and a method for use, including treating acute hypovolemia due to any number of medical conditions due to sepsis with shock, hemorrhagic shock, hypovolemic shock, b... | 04/13/2010 |
| 7696175 | Combination cancer immunotherapy with co-stimulatory molecules Provided are methods of reducing the size of a tumor or inhibiting the growth of cancer cells in an individual or inhibiting the development of metastatic cancer by administering an effective amount of a soluble form of a co-stimulatory molecule from an antigen pres... | 04/13/2010 |
| 7648965 | Method for fostering bone formation and preservation A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The metho... | 01/19/2010 |
| 7531518 | Method for fostering bone formation and preservation A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The metho... | 05/12/2009 |
| 7465711 | Treatment of cancers of lymphocytic cells with product R A method of treating a patient suffering from cancers of lymph cells such as acute lymphocytic leukemia, chronic lymphocytic leukemia, Hodgkin's disease and non-Hodgkin's lymphoma comprises parenterally administering to said patient an effective acute lymphocytic le... | 12/16/2008 |
| 7442308 | Process for removing viruses in fibrinogen solutions and fibrinogen obtained by said process A process for removing viruses in fibrinogen solutions and fibrinogen obtained thereof wherein the process starts with an adjusted purified fibrinogen solution, the adjusted purified solution is frozen and then thawed at a temperature between 5 and 20° C., the undi... | 10/28/2008 |
| 7439234 | Method for treating cancer patients undergoing chemotherapy A method for treating cancer patients undergoing chemotherapeutic treatments by administering Product R, a peptide-nucleic acid preparation, is disclosed. ... | 10/21/2008 |
| 7432241 | Device for treating diabetes and methods thereof A composite supported vascular graft comprising Vascular Endothelial Growth Factor (VEGF) and/or Platelet Derived Growth Factor (PDGF) for enhanced site-specific angiogenesis and methods thereof are disclosed. At least one VEGF, PDGF or angiogenesis factor is incorp... | 10/07/2008 |
| 7429567 | Sustained delivery of PDGF using self-assembling peptide nanofibers The present invention is directed to a therapeutic composition in which human PDGF is bound directly to peptides that self assemble into a biologically compatible gel. When implanted in a patient's body, the composition provides for the slow, sustained release of PD... | 09/30/2008 |
| 7425542 | Stabilizing alkylglycoside compositions and methods thereof The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptid... | 09/16/2008 |
| 7419683 | Method of inhibiting side effects of pharmaceutical compositions containing amphiphilic vehicles or drug carrier molecules A method is provided for inhibiting or preventing toxicity and other unwanted effects (a) caused by solvents for pharmaceuticals which solvents or emulsifier which contain amphiphilic molecules such as polyethoxylated oils or a derivative thereof, or (b) caused by a... | 09/02/2008 |
| 7417023 | Targeted delivery of bioaffecting compounds for the treatment of cancer A homogeneous conjugate for targeting and treating diseased cells wherein the conjugate comprises an anti-cancer drug and a targeting protein, wherein said anti-cancer drug is selected from the group consisting of heat sensitizers, photosensitizers and apoptosis ind... | 08/26/2008 |
| 7407934 | Methods for regulating postprandial blood glucose Methods for treating conditions associated with elevated, inappropriate or undesired post-prandial blood glucose levels are disclosed which comprise administration of an effective amount of an amylin agonist alone or in conjunction with other anti-gastric emptying a... | 08/05/2008 |
| 7402655 | Molecules designated LDCAM The invention is directed to LDCAM as a purified and isolated protein, the DNA encoding the LDCAM, host cells transfected with cDNAs encoding LDCAM, processes for preparing LDCAM polypeptides and compositions and methods for treating utilizing LDCAM polypeptides. | 07/22/2008 |
| 7393829 | Pharmaceutical compositions comprising fragments and homologs of troponin subunits The present invention relates to pharmaceutical compositions comprising therapeutically effective amounts of fragments or homologs of troponin C, I or T subunits for the treatment of diseases or disorders involving abnormal angiogenesis. ... | 07/01/2008 |
| 7388124 | Non-traumatic model for neurogenic pain A method for producing a non-human mammalian model for neurogenic pain is provided, which includes altering a peripheral nerve of a non-human mammal by non-surgically placing a gel substance into the fascial tunnel through which the peripheral nerve passes. The plac... | 06/17/2008 |
| 7388071 | Composition and method for inducing and enhancing a telomerase reverse transcriptase-reactive cytotoxic T lymphocyte response Telomerase peptides that bind MHC are disclosed. The instant application also discloses vaccines containing said peptides and methods of using said peptides to enhance a CTL response against mammalian cancer cells. ... | 06/17/2008 |
| 7384916 | Methods and compositions for preventing and treating aging or photodamaged skin Disclosed are methods for treating aging and photodamaged skin employing topical application of compositions which comprise at least one peptide manganese complex. Also disclosed are methods wherein the composition further comprises retinol, at least one retinol der... | 06/10/2008 |
| 7384918 | Botulinum toxin for treating muscle contracture The invention provides for the use of a botulinum toxin to treat contracture, such as muscle contracture, in patients by transdermal administration of the botulinum toxin. ... | 06/10/2008 |
| 7378389 | Botulinum toxin neurotoxic component for treating juvenile cerebral palsy The invention provides for the use of a presynaptic neurotoxin (for example a bacterial neurotoxin such as botulinum toxin A) for the manufacture of a medicament for the treatment of cerebral palsy in juvenile patients. The juvenile patients are preferably juveniles... | 05/27/2008 |
| 7378096 | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or grp170 polypeptide complexed with an immunogenic polypeptide. The immuno... | 05/27/2008 |
| 7375080 | Immobilized lactoferrin (Im-LF) antimicrobial agents and uses thereof Disclosed is a composition of matter comprising a defined dispersion of lactoferria immobilized on a naturally occuring substrate via the N-terminus region of the lactoferrin. Compositions comprising immobilized lactoferrin (Im-LF) are used in a method for reducing ... | 05/20/2008 |
| 7371399 | Polymer gel containing hyaluronic acid and collagen, and its use in joints Formulations and methods for treating joints, such as temporomandibular joint disorders, osteoarthritis of the knee, hip and other types of inflammatory joint diseases. The method involves identifying specific matrix metalloproteinases (MMPs) that may be responsible... | 05/13/2008 |
| 7371411 | Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells The present invention relates to a composite for the treatment of a variety of medical conditions, the composite comprising an oxidized glutathione-based compound, which has a disulfide bond, and a metal material, in particular where the metal is either platinum or ... | 05/13/2008 |
| 7371721 | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes The present invention relates to methods for prevention and treatment of bone-related disorders and calcium homeostasis related syndromes using a GLP-2 molecule or GLP-2 activator either alone or in combination with another therapeutic. The present invention also en... | 05/13/2008 |
| 7368425 | Cyclic peptides for modulating growth of neo-vessels and their use in therapeutic angiogenesis The present disclosure teaches analogs of human chemokines and methods of using them in the prevention, treatment, and ameliorization of diseases that can benefit from therapeutic angiogenesis. The teachings are generally directed to compositions comprising SDF-1 mi... | 05/06/2008 |
| 7368431 | Polypeptide, the conjugate thereof with doxorubicine and a pharmaceutical composition based thereon The inventive polypeptide is embodied in the form of a similar fragment of the epidermal growth factor of aminoacid ranging from 21 to 31 and capable of efficiently binding with the receptor of the epidermal growth factor as a vector for the directed supply of antic... | 05/06/2008 |
| 7368531 | Human secreted proteins The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding the polypeptides, useful for diagnosing and treating diseases, disorders, and/or conditions related to the human secreted proteins. Antibodies that bind these ... | 05/06/2008 |
| 7358342 | Preparation derived from shark cartilage for treatment of diseased related to excessive PHF or excessive intracellular calcium A preparation derived from shark cartilage for the treatment of diseases related to excessive PHF or Excessive intracellular calcium. ... | 04/15/2008 |
| 7358284 | Particulate acellular tissue matrix A method of processing an acellular tissue matrix to give a particulate acellular tissue matrix includes: cutting sheets of dry acellular tissue matrix into strips; cryofracturing the dry acellular tissue matrix strips at cryogenic temperatures; separating the resul... | 04/15/2008 |
| 7357915 | Method of imaging cell death in vivo A method of imaging apoptosis in vivo, using radiolabeled annexin, is described. ... | 04/15/2008 |
| 7358332 | Bioactive peptides, uses thereof and process for the production of same Novel bioactive peptide compositions and process for producing the same and the use of such compositions for enhancing the growth of warm blooded animals and fish is disclosed. ... | 04/15/2008 |
| 7355149 | Coil unit, process for producing the same, and image heating apparatus An electromagnetic induction coil unit for use with an electromagnetic induction heating-type image heating apparatus includes magnetic flux generation means comprising an exciting coil and a magnetic core; a core holder for holding the magnetic core; a coil holder ... | 04/08/2008 |
| 7354896 | Administration of leptin A method and composition for administering leptin to a subject. The invention includes suspending isolated native leptin-containing milk fat globules in a suitable medium for administering to a subject. The suspended milk fat globules may be administered orally as w... | 04/08/2008 |
| 7354702 | Processing tissue to produce a biopolymer scaffold for tissue engineering A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue, particularly fetal or neo-natal tissue, to chemical and mechanical processing. The process includes, but is not limited to, harvesting the tissue, optional... | 04/08/2008 |
