Celebrity Inventors
Glam girl Heddy Lamar may have used her good looks to good effect on the silver screen, but she put her smarts to better use as an inventor. During World War II, she co-patented a frequency-switching system for torpedo guidance that was considered years ahead of its time.
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| Number | Title | Issue Date |
| 7960372 | Bivalent Smac mimetics and the uses thereof The invention relates to bivalent mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis. ... | 06/14/2011 |
| 7842683 | Neurotherapeutic compositions and method Administration of β-Lactam compounds, including β-lactam antibiotics and β-lactamase inhibitors provides significant neurotropic effects in warm-blooded vertebrates evidence inter alia by anxiolytic and anti-aggressive behavior modification and enhanced cognition... | 11/30/2010 |
| 7488724 | 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors The invention provides compounds of formula (I): wherein: R1-R4 and A have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting β-lact... | 02/10/2009 |
| 7358237 | Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2 Cyclooxygenase (COX2) and inducible nitric oxide synthase (iNOS) are two major inflammatory mediators. Inducible NOS specifically binds to COX2 and S-nitrosylates it, enhancing COX2 catalytic activity. Selectively disrupting iNOS—COX2 binding prevents NO-mediated ... | 04/15/2008 |
| 7351419 | Oral pharmaceutical suspension of Cefdinir crystal The present invention relates to a novel oral pharmaceutical suspension of Cefdinir crystal. More specifically, the present invention relates to a novel kit for preparation of an oral pharmaceutical suspension containing crystal form C Cefdinir. ... | 04/01/2008 |
| 7332471 | Cross-linked glycopeptide-cephalosporin antibiotics This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacter... | 02/19/2008 |
| 7307062 | Method for treating a mental disorder A method of treating an individual exhibiting at least one symptom of a mental disorder is provided which comprises administering to the individual an antimicrobial composition in an amount effective to inhibit or eliminate the at least one symptom of the disorder. ... | 12/11/2007 |
| 7288520 | Cyclosporin compositions A composition is disclosed herein comprising from about 0.001% to about 0.4% cyclosporin A, castor oil, and a surfactant selected from the group consisting of alcohol ethoxylates, alcohols, alkyl glycosides, alkyl polyglycosides, alkylphenol ethoxylates, amine oxide... | 10/30/2007 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7244842 | Amorphous hydrate of a cephalosporin antibiotic A process for the preparation of cefdinir of the formula (I) the said process comprising the steps of: i) condensing 7-amino-3-cephem-4-carboxylic acid of the formula (XII) wherein R1 is as defined above with compound of the formula (XIII) in the presence of a terti... | 07/17/2007 |
| 7189708 | Topical composition for skin A topical skin composition containing a dipeptide compound represented by formula (1) or a salt of the dipeptide: wherein R1 represents a hydrogen atom, an alkyl group, an alkanoyl group, or —CH(R | 03/13/2007 |
| 7169811 | Composition based on ethyl ester of linoleic acid and triethyl ester of citric acid for topical use in the treatment of seborrhea and acne The present invention relates to a composition for topical use for treating and improving the aesthetic conditions of the skin, which comprises, as an active ingredient, a mixture of ethyllinoleate and triethylcitrate. This composition is active in the treatment of ... | 01/30/2007 |
| 7157095 | Multiple-delayed release antifungal product, use and formulation thereof An anti-fungal product is comprised of at least three delayed release dosages forms, each of which has a different release profile, with the Cmax for the anti-fungal product being reached in less than about twelve hours after initial release of anti-funga... | 01/02/2007 |
| 7125986 | Penicillanic acid derivative compounds and methods of making Compounds of formula I: wherein R1, R2, R3, R4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for in... | 10/24/2006 |
| 7122204 | Antibiotic composition with inhibitor Antibiotic composition having four dosage forms with different release profiles providing for initial release of a beta lactam antibiotic followed by release of a beta-lactamase inhibitor, followed by release of the antibiotic followed by release of the inhibitor. I... | 10/17/2006 |
| 7105174 | Multiple-delayed release anti-neoplastic product, use and formulation thereof An anti-neoplastic product is comprised of at least three delayed release dosages forms, each of which has a different release profile, with the Cmax for the anti-neoplastic product being reached in less than about twelve hours after initial release of an... | 09/12/2006 |
| 7101572 | Taste masked aqueous liquid pharmaceutical composition A substantially taste masked liquid pharmaceutical composition containing a pharmaceutically effective amount of an unpleasant tasting drug dissolved or dispersed in an aqueous excipient base, said excipient base comprising polyvinyl pyrrolidone and/or copolyvidone,... | 09/05/2006 |
| 7087588 | Nitric oxide donors capable of reducing toxicity from drugs Use of organic compounds containing the —ONO2 function, or inorganic compound containing the —NO group or compositions comprising said compounds to reduce the toxicity caused by drugs to the gastrointestinal and/or renal apparatus, said compounds bein... | 08/08/2006 |
| 7081253 | Use of nanodispersions in pharmaceutical end formulations A description is given of the use of a nanodispersion, which comprises (a) a membrane-forming molecule, (b) a coemulsifier and (c) a lipophilic component, in pharmaceutical end for... | 07/25/2006 |
| 7074417 | Multiple-delayed release anti-viral product, use and formulation thereof An anti-viral product is comprised of at least three delayed release dosage forms, each of which has a different release profile, with the Cmax for the anti-viral product being reached in less than about twelve hours after initial release of anti-viral fr... | 07/11/2006 |
| 7025989 | Multiple-delayed released antibiotic product, use and formulation thereof An antibiotic product is comprised of at least three delayed release dosages forms, each of which has a different release profile, with the Cmax for the antibiotic product being reached in less than about twelve hours. ... | 04/11/2006 |
| 7011826 | Control of acidosis The present invention relates to a vaccine for the prevention of lactic acidosis in a vertebrate, said vaccine comprising at least one isolated microorganism, or fragment or fragments thereof, wherein said microorganism is capable of producing lactic acid within the... | 03/14/2006 |
| 6998397 | Method for decreasing cholesterol level in blood A method for improving blood cholesterol and its conjugates levels in a mammal, which is based on the administration of steroidal plant hormone 24-epibrassinolide. ... | 02/14/2006 |
| 6979735 | Agglomerates by crystallization The present invention describes novel agglomerates in crystalline form of β-lactam compounds. Furthermore, a process for the preparation of said agglomerates, wherein a solution or suspension of at least one β-lactam compound in a solvent is mixed with one or more... | 12/27/2005 |
| 6949521 | Therapeutic azide compounds Pharmaceutical prodrug compositions are provided comprising azide derivatives of drugs which are capable of being converted to the drug in vivo. Azide derivatives of drugs having amine, ketone and hydroxy substituents are converted in vivo to the corresponding drugs... | 09/27/2005 |
| 6929804 | Anti-fungal composition An anti-fungal product for delivering at least two different anti-fungals that is comprised of three dosage forms with different release profiles with each anti-fungal being present in at least one of the dosage forms. ... | 08/16/2005 |
| 6916801 | 7-Alkylidene-3-substituted-3-cephem-4-carboxylates as β-lactamase inhibitors The invention provides compounds of formula (I): wherein: R1-R4 and A have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting β... | 07/12/2005 |
| 6906054 | Compositions for inhibiting beta-lactamase The invention provides pharmaceutical compositions comprising compounds of formula I and IV: wherein R1-R11 and A have any of the values defined in the specification, and ... | 06/14/2005 |
| 6869976 | Inorganic-polymer complexes for the controlled release of compounds including medicinals This invention relates generally to the production and use of inorganic-polymer complexes for the controlled release of compounds including medicinals. Advantageously, the inorganic used is calcium sulfate. ... | 03/22/2005 |
| 6709678 | Easy to swallow oral medicament composition An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance, the particles being combined with one or more gelling or swelling agent... | 03/23/2004 |
| 6645959 | Method for treating postoperative ileus This invention is a method for preventing or treating postoperative ileus comprising administering a vasopressin antagonist such as a compound of Formula (1), where R1, R2, and R3 include hydrogen, halo, alkyl, and alkoxy;... | 11/11/2003 |
| 6627625 | Treatment of behavioral disorders with ଲ-lactam compounds Administration of ଲ-lactam compounds including ଲ-lactam antibiotics and ଲ-lactamase inhibitors provides significant neurotropic effects in warm-blooded vertebrates evidenced inter alia by anxiolytic and anti-aggressive behavior modificat... | 09/30/2003 |
| 6599892 | 7-alkylidene cephalosporanic acid derivatives and methods of using the same Derivatives of 7-alkylidene cephalosporanic acid sulfone and the pharmaceutically active salts thereof are found to be potent inhibitors of ଲ-lactamase enzymes.... | 07/29/2003 |
| 6583133 | Propenyl cephalosporin derivatives and process for the manufacture thereof Disclosed are cephalosporin derivatives of the general formula ##STR1## wherein R is an organic residue with a molecular weight not exceeding 400 bonded to the adjacent sulphur atom via carbon and consisting of carbon, hydrogen, and optional oxygen, sulfu... | 06/24/2003 |
| 6565882 | Antibiotic composition with inhibitor Antibiotic composition having four dosage forms with different release profiles providing for initial release of a beta lactam antibiotic followed by release of a beta-lactamase inhibitor, followed by release of the antibiotic followed by release of the i... | 05/20/2003 |
| 6537985 | Antibiotic formulation and a method of making this formulation An antibiotic formulation in a true solution is provided. This formulation includes an antibiotic and N-methyl-2-pyrrolidone. It also may include a preservative, an antioxidant, and/or an additive. The antibiotic is a beta lactam, such as a penicillin, a ... | 03/25/2003 |
| 6537984 | Uses of diterpenoid triepoxides as an anti-proliferative agent Combinations of diterpenoid triepoxides and anti-proliferative agents are used in a combination therapy to treat hyperproliferative disorders. Anti-proliferative agents of interest include agents active in killing tumor cells, as well as immunosuppressant... | 03/25/2003 |
| 6531465 | Antibacterial cephalosporins A compound of formula ##STR1## wherein Ac, R1 and R2 have various meanings, a process for a preparation thereof and its use as a pharmaceutical, i.e. as antibacterial agent.... | 03/11/2003 |
| 6489319 | Neurotherapeutic use of carboxypeptidase inhibitors Administration of inhibitors of carboxypeptidase E provides significant neurotropic effects in warm-blooded vertebrates evidenced inter alia by anxiolytic and anti-aggressive behavior and enhanced cognition. Certain ଲ-Lactam antibiotics, most signif... | 12/03/2002 |
| 6486149 | Composition comprising a crystallographically stable, amorphous cephalosporin and processes for the preparation thereof Processes are provided for the preparation of orally administrable, yellow and powdery compositions essentially consisting of particles composed of a homogeneous mixture of an amorphous Cefditoren pivoxil substance with a water soluble high-molecular addi... | 11/26/2002 |
