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| Number | Title | Issue Date |
| 7232572 | Methods of treating rosacea A method of treating rosacea in a human in need thereof comprising administering to said human a tetracycline compound in an amount that is effective to treat rosacea, but has substantially no antibiotic activity. ... | 06/19/2007 |
| 7169808 | Compounds useful for the preparation of medicaments with phosphodiesterase IV inhibitory activity Formula (I) compounds are described, where the groups are defined in the description, as well as processes for their preparation and their use as medicaments, particularly as selective phosphodiesterase IV inhibitors. ... | 01/30/2007 |
| 7119083 | β-Lactamyl vasopressin VAntagonists Novel 2-(azetidin-2-on-1-yl)alkanedioic acid derivatives and 2-(azetidin-2-on-1-yl)alkoxyalkanoic acid derivatives are described for use in the treatment of disease states responsive to antagonism of the vasopressin V1a receptor. ... | 10/10/2006 |
| 6974801 | Inhibitors and methods of use thereof New triterpenoid derivatives with various substituents at the C-17 position of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO) were synthesized. Among them, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile (CNDDO), 1-(2-cyano-3,12-dioxooleana-1,9(11)-dien-... | 12/13/2005 |
| 6949521 | Therapeutic azide compounds Pharmaceutical prodrug compositions are provided comprising azide derivatives of drugs which are capable of being converted to the drug in vivo. Azide derivatives of drugs having amine, ketone and hydroxy substituents are converted in vivo to the corresponding drugs... | 09/27/2005 |
| 6884784 | Diagnosis and management of infection caused by chlamydia The present invention provides a unique approach for the diagnosis and management of infections by Chlamydia species, particularly C. pneumoniae. The invention is based, in part, upon the discovery that a combination of agents directed toward the vario... | 04/26/2005 |
| 6709678 | Easy to swallow oral medicament composition An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance, the particles being combined with one or more gelling or swelling agent... | 03/23/2004 |
| 6706290 | Methods for eradication of nanobacteria Nanobacteria contribute to pathological calcification in the human and animal body, including diseases such as kidney stones, salivary gland stones, dental pulp stones and atherosclerosis. The present invention provides methods for sterilizing articles contaminated ... | 03/16/2004 |
| 6627625 | Treatment of behavioral disorders with ଲ-lactam compounds Administration of ଲ-lactam compounds including ଲ-lactam antibiotics and ଲ-lactamase inhibitors provides significant neurotropic effects in warm-blooded vertebrates evidenced inter alia by anxiolytic and anti-aggressive behavior modificat... | 09/30/2003 |
| 6579854 | Diagnosis and management of infection caused by chlamydia The present invention provides a unique approach for the diagnosis and management of infections by Chlamydia species, particularly C. pneumoniae. The invention is based, in part, upon the discovery that a combination of agents directed toward the various ... | 06/17/2003 |
| 6569839 | Fast-acting pharmaceutical compositions and methods of use A pharmaceutical composition comprising at least one local anesthetic, at least one anti-inflammatory agent and at least one antibiotic are disclosed. The local anesthetic has a peak effect no later than about 10 minutes after administration to a mammal, ... | 05/27/2003 |
| 6544991 | Compositions and methods for treating bacterial infections A composition having antibacterial activity is disclosed. More particularly, a mixture of an oxazolidinone compound, sulbactam, and ampicillin active agents, demonstrating activity against resistant strains of bacteria is disclosed. Methods for using an o... | 04/08/2003 |
| 6537985 | Antibiotic formulation and a method of making this formulation An antibiotic formulation in a true solution is provided. This formulation includes an antibiotic and N-methyl-2-pyrrolidone. It also may include a preservative, an antioxidant, and/or an additive. The antibiotic is a beta lactam, such as a penicillin, a ... | 03/25/2003 |
| 6514955 | Multi-faceted method to repress reproduction of latent viruses in humans and animals Disclosed are methods for repressing reproduction of latent viruses, such as HIV, in animals by the generally concurrent administration of (1) antioxidants including a glutathione agent; and (2) an NFKB induction inhibitor. Also disclosed are pharmaceutic... | 02/04/2003 |
| 6429191 | Treatment of hearing impairments Compositions and methods are provided for prophylactic or therapeutic treatment of a mammal for hearing impairments involving neuronal damage, loss, or degeneration, preferably of spinal ganglion neurons, by administration of a therapeutically effective a... | 08/06/2002 |
| 6380181 | Synthetic catechol derivatives, method for production and use thereof Catechol derivatives of general formula (I) ##STR1## in which R1 denotes O-acyl and R2 represents amino acid residues in the 3- and/or 4-position function as siderophores and/or as biological chelating agents for iron in gram-negativ... | 04/30/2002 |
| 6316015 | Hyperbactericidal surfaces A surface is provided with antibiotic or antiseptic properties. A solid substrate is modified by covalently fixing one or more spacers having reactive extremities via a proximate reactive extremity, and one or more antibiotic, bactericidal, viricidal or f... | 11/13/2001 |
| 6271212 | Prodrug azide compositions and compounds Pharmaceutical prodrug compositions are provided comprising azide derivatives of drugs which are capable of being converted to the drug in vivo. Azide derivatives of drugs having amine, ketone and hydroxy substituents are converted in vivo to the correspo... | 08/07/2001 |
| 6238659 | Agent for treating papilloma virus-positive malignant and premalignant lesions The present invention relates to a preparation comprising a substance influencing the cellular redox state for treating papilloma virus-positive malignant lesions.... | 05/29/2001 |
| 6225282 | Treatment of hearing impairments Compositions and methods are provided for prophylactic or therapeutic treatment of a mammal for hearing impairments involving neuronal damage, loss, or degeneration, preferably of spinal ganglion neurons, by administration of a therapeutically effective a... | 05/01/2001 |
| 6174876 | Use of boswellic acid for treating brain tumors The present invention relates to the use of pure boswellic acid, a physiologically acceptable salt, a derivative, a salt of said derivative or a vegetable preparation containing boswellic acid for the preparation of a pharmaceutical composition for the tr... | 01/16/2001 |
| 6156346 | Urease-responsive delivery systems for diagnostic and therapeutic applications A delivery system that releases a diagnostic marker or therapeutic agent in a manner sensitive to the concentration of urease in a physiological compartment, particularly the gastrointestinal tract, and methods of use.... | 12/05/2000 |
| 6013647 | Benzoxazinedione derivatives, method of producing them and uses thereof This invention relates to new benzoxazinedione derivatives corresponding to the formula I: ##STR1## wherein R1 =H or carboxyalkyl, R2 =H, alkyl or phenyl, and R3 represents different acid groups derived from amino aci... | 01/11/2000 |
| 5994340 | Azetidinone derivatives as ଲ-lactamase inhibitors New 2-oxo-1-azetidine sulfonic acid derivatives with an aminoalkyl substituted "anti" (E-isomer) oxyimino group in the acylamino substituent at the 3 position of the monobactam ring. These compounds are potent inhibitors of bacterial ଲ-lactamases. T... | 11/30/1999 |
| 5948422 | Oral dosage-forms containing a ଲ-lactam antibiotic A granulate, containing at least 50 wt. % of a water soluble ଲ-lactam antibiotic, is provided. A process to prepare a granulate containing such ଲ-lactam antibiotic comprises moistening components making up the granulate with an aqueous solutio... | 09/07/1999 |
| 5883074 | Potentiators of antibacterial agents Methods for screening for compounds which potentiate the activity of antibacterial agents against bacteria resistant to the antibacterial agent alone, pharmaceutical compositions including such potentiators, and methods of treating bacterial infections us... | 03/16/1999 |
| 5849797 | D-ଲ-lysylmethanediamine derivatives and preparation thereof Now are provided (R)-3,6-diamino-N-(ω-aminoalkyl)-hexanamides which are novel compounds having the general formula (I): ##STR1## wherein n stands for 2-5, and which may be for example, (R)-3,6-diamino-N-(2-aminoethyl)hexanamide (n=2) and (R)-3,... | 12/15/1998 |
| 5846961 | Multi-faceted method to repress reproduction of latent viruses in humans and animals Disclosed are methods for repressing reproduction of latent viruses, such as HIV, in animals by the generally concurrent administration of (1) antioxidants including a glutathione agent; and (2) an NFKB induction inhibitor. Also disclosed are pharmaceutic... | 12/08/1998 |
| 5780049 | Enhanced skin penetration system for improved topical delivery of drugs The invention involves pharmaceutical compositions for topical application comprising: (a) a safe and effective amount of a pharmaceutical active; and (b) from about 0.05% to about 5% of a non-ionic polyacrylamide having a molecular wight of from about 1,000,0... | 07/14/1998 |
| 5712268 | Compositions of tricyclic ଲ-lactams and uses thereof There are described pharmaceutical compositions comprising (a) compounds of the formula ##STR1## in which R signifies lower alkoxycarbonyl, lower alkoxy-carbonylamino, the acyl residue of an - or ଲ-amino acid or a residue of the general... | 01/27/1998 |
| 5698533 | Ophthalmic pharmaceutical composition A method of administering a drug to an eye including the steps of: (a) admixing a pharmaceutically acceptable hydrocarbonaceous semi-solid or oil which contains the drug with water at a temperature above the melting point of the semi-solid or oil; and (b)... | 12/16/1997 |
| 5698577 | Compositions of bicyclic ଲ-lactams and uses thereof There are described pharmaceutical compositions comprising (a) compounds of the formula ##STR1## in which R signifies lower alkoxycarbonyl, lower alkoxy-carbonylamino, the acyl residue of an - or ଲ-amino acid or a residue of the general... | 12/16/1997 |
| 5686436 | Multi-faceted method to repress reproduction of latent viruses in humans and animals Disclosed are methods for repressing reproduction of latent viruses, such as HIV, in animals by the generally concurrent administration of (1) antioxidants including a glutathione agent; and (2) an NFKB induction inhibitor. Also disclosed are pharmaceutic... | 11/11/1997 |
| 5674858 | Medicaments for treating gastrointestinal disorders The use is described of both (i) ranitidine bismuth citrate and (ii) one or more Helicobacter pylori-inhibiting antibiotics in treating or preventing gastrointestinal disorders. Pharmaceutical compositions containing both (i) and (ii) and methods for the ... | 10/07/1997 |
| 5650394 | Use of urinastatin-like compounds to prevent premature delivery The present invention provides a method of diagnosing and treating a pregnant female at risk for impending preterm delivery. The method comprises the step of diagnosing imminent preterm delivery by testing with a method that has a sensitivity of at least ... | 07/22/1997 |
| 5643902 | Veterinary treatment A formulation comprising amoxycillin or a veterinarily acceptable derivative thereof, clavulanic acid or a veterinarily acceptable derivative thereof, and a veterinarily acceptable carrier is used in the treatment of farrowing fever and/or bacterial pneum... | 07/01/1997 |
| 5607671 | Medical use, a medical method and a pharmaceutical preparation The invention concerns medical use, a medical method and a pharmaceutical preparation. The invention allows the action of ଲ-lactam antibiotics to be targeted and their side effects to be reduced by inactivation of part of the antibiotic in a desired... | 03/04/1997 |
| 5599795 | Method for treatment of idiopathic inflammatory bowel disease (IIBD) A new method for the prevention and treatment of Idiopathic inflammatory Bowel Disease (IIBD), including Crohn's Disease and Ulcerative Colitis, in human patients is provided. The key steps include sterilizing the intestinal tract with multiple antibiotic... | 02/04/1997 |
| 5478819 | Phospholipid composition and use thereof A method of and composition for treating a Helicobacter pylori infection in a mammal. The method comprises administering to said mammal orally a therapeutically effective amount of a Helicobacter pylori eradicating antibiotic and a phospholipid. The compo... | 12/26/1995 |
| 5397778 | Enteral formulations for treatment of inflammation and infection The present invention features saponin containing enteral formulations for treatment of infection and inflammation. These saponin containing formulations are particularly useful in conjunction with oils rich in ω3 polyunsaturated fatty acids such as fish... | 03/14/1995 |
