...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7375215 | Compounds for PDT A tetrakis(hydroxyphenyl)chlorin, bacteriochlorin or isobacteriochlorin, derivatised at one or more of the hydroxy groups by addition reaction with a diisocyanate, diisothiocyanate or isocyanate-isothiocyanate at one isocyanate or isothiocyanate group thereof, the o... | 05/20/2008 |
| 7323452 | Method for the accelerated in vivo removal of ethanol A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as catalysts or “pseudo” enzymes for the oxidation. These additives... | 01/29/2008 |
| 7205289 | Combinations of active ingredients with insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 04/17/2007 |
| 7097701 | Phthalocyanine compound, ink, inkjet recording method, and image forming method An ink containing a phthalocyanine compound represented by the formula (I): wherein X1 to X4, Y1 to Y4, A1 to A4, and M are defined herein. ... | 08/29/2006 |
| 7011854 | Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g., rheumatoid arthritis, and of diseases with a strong inflammatory component, such as atherosclerosis, stroke... | 03/14/2006 |
| 6992047 | Method of microencapsulating an agricultural active having a high melting point and uses for such materials A method of producing a controlled release form of an agricultural active material includes the provision of an organic liquid composition in which the active is present, but where the liquid composition is free from aromatic solvents and is maintained below the nor... | 01/31/2006 |
| 6906050 | Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and MRI diagnosis Substituted porphyrin and azaporphyrin deviations with various substitutents in the 12- and 17-positions of the porphyrin skeleton as pharmaceutical agents for use in photodynamic therapy, MRI diagnosis, and radiodiagnostics. ... | 06/14/2005 |
| 6833362 | Method and composition for the accelerated in vivo removal of ethanol A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or “pseudo” enzymes for the oxidation. Additives include the oxidant Nicotinami... | 12/21/2004 |
| 6630172 | Microbicidal composition containing potassium sodium tartrate Disinfectant formulations are described which are preferably ecologically friendly and non-toxic to mammals and plants, and are highly effective against a broad spectrum of detrimental pathogenic microorganisms. The microbicidal formulation contains compl... | 10/07/2003 |
| 6608050 | Lyophilizate of lipid complex of water insoluble porphyrins The present invention relates to a pharmaceutically acceptable dosage form of water insoluble porphyrins, particularly metal containing porphyrins such as tin porphyrin, which can be complexed with a lipid, reconstituted from a lyophilizate and administra... | 08/19/2003 |
| 6602487 | Methods and tests for producing and for inhibiting coronary artery vasospasms Methods for producing coronary vasospasms and for inhibiting coronary vasospasms are disclosed. Both in vivo and in vitro methods are disclosed. The methods are useful as tests for determining the ability of a chemical compound to inhibit or reduce corona... | 08/05/2003 |
| 6384027 | Phthalocyanine analogs Disclosed are compounds of formula V ##STR1## wherein M is selected from: a metal atom; a metal compound; 2H whereby one H is bonded to each of the two nitrogen atoms depicted as being bonded to M (positions 29 and 31 shown) R3 is H or methyl; ... | 05/07/2002 |
| 6287541 | Oral care compositions The invention relates to an oral care composition with antiplaque agents. The antiplaque agents are complexes of divalent copper, zinc, iron or tin, or trivalent iron with a specific class of cyclic -hydroxyketones. A typical example is the copper ... | 09/11/2001 |
| 6147070 | Methods and compositions for controlling iron stores to treat and cure disease states Methods and compositions of matter are provided that enable a phased reduction of body iron stores to near a iron deficiency level, and thereafter maintain the body iron stores at that level by reducing further iron accumulation. In a first phase, a patie... | 11/14/2000 |
| 6133252 | Fungicides for the control of take-all disease of plants A method of controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula ##STR1## wherein Z1 and Z2 are C or N and are part of an aromatic ring selected from benzene, p... | 10/17/2000 |
| 5916885 | Topical administration of certain azaspiranes to prevent or treat skin conditions associated with hyperproliferation of skin cells and/or immunologically mediated disorders A locally administrable topical pharmaceutical composition is provided for prevention or treatment of skin conditions associated with hyperproliferation of skin cells and/or an immunologically mediated disorder, e.g., psoriasis, atopical dermatitis, conta... | 06/29/1999 |
| 5843936 | Topical administration of azaspiranes to prevent or treat skin conditions associated with hyperproliferation of keratinocytes A locally administrable topical pharmaceutical composition is provided for use in the prevention or treatment of skin conditions associated with hyperproliferation of keratinocytes and/or an immunologically mediated disorders, as psoriasis, atopic dermati... | 12/01/1998 |
| 5811411 | Fungicides for the control of take-all disease of plants A method of controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula ##STR1## wherein Z1 and Z2 are C and are part of an aromatic ring that is thiophene; A is selec... | 09/22/1998 |
| 5504075 | Modification of DNA and oligonucleotides using metal complexes of polyaza ligands A process is provided for oxidatively modifying nucleic acids containing a target nucleotide. The nucleic acid is contacted with a polyaza metal complex in the presence of an oxidizing agent so that the nucleic acid is modified at or near the target nucle... | 04/02/1996 |
| 4971989 | Substituted 1-arylpyrazoles, pesticidal compositions and use Substituted 1-arylpyrazoles useful in combating insects having the arachnida and nematodes of the formula ##STR1## in which R1 represents hydrogen or alkyl, R2 represents alkyl or halogenoalkyl, R3 represents hydrogen or a... | 11/20/1990 |
| 4935408 | Organotin compounds and pesticides containing them A compound of the formula: ##STR1## in which R1 represents alkyl, cycloalkyl or aralkyl, R* represents fluorophenyl or trifluoromethylphenyl when R1 is alkyl; R* represents dichlorophenyl, neopentyl, trimethylsilylmethyl, dimeth... | 06/19/1990 |
| 4877446 | Pesticides based on pyrimidine derivatives A method of combating fungi which comprises applying to such fungi or to a fungus habitat a fungicidally effective amount of a substituted pyrimidine of the formula ##STR1## in which Ar represents optionally substituted phenyl, X represents oxygen, s... | 10/31/1989 |
| 4843068 | Pyrazole oxime derivatives and compositions A pyrazole oxime derivative represented by the general formula (I) which is useful as an insecticide and fungicide, ##STR1## wherein the structural elements are defined in the specification, and the method of controlling said pests. The compounds rep... | 06/27/1989 |
| 4774235 | Organotin compounds and pesticides containing them A compound of the formula: ##STR1## in which R1 represents alkyl, cycloalkyl or aralkyl, R* represents fluorophenyl or trifluoromethylphenyl when R1 is alkyl; R* represents dichlorophenyl, neopentyl, trimethylsilylmethyl, dimeth... | 09/27/1988 |
| 4732894 | Fungicidal insecticidal and acaricidal tin salts of heterocyclic hydroxamic acids Compounds of the formula ##STR1## wherein Het is a 5- or 6-membered aromatic heterocyclic ring containing 1 to 2 ring nitrogen atoms and the remaining ring atoms carbon atoms optionally substituted with 1 to 2 substituents independently selected ... | 03/22/1988 |
| 4690942 | 1-aryl-2-fluoro-2-azolyl alkanones, alkanols, esters, and ethers, composition containing them, and use of them to control phytopathogenic microorganisms The invention relates to 1-aryl-2-fluoro-2-azolyl alkanones, alkanols, esters and ethers of formula I ##STR1## wherein Az is 1H-1,2,4-triazole, 4H-1,2,4-triazole or 1H-imidazole; T is --C(O)--, --CH(OH)-- or one of the groups ##STR2## wherein R | 09/01/1987 |
| 4690947 | Synergistic composition for the control of arthropods Arthropodicidal compositions in the form of synergistic combinations of (A) cyano-(4-fluoro-3-phenoxyphenyl)-methyl 3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropanecarboxylate plus (B) O-ethyl-O-[4-(methylthio)-phenyl]-S-propyl phosphorodithioate, (A) plus... | 09/01/1987 |
| 4622333 | Fungicidal hydroxyalkynyl-azolyl derivatives Hydroxyalkynyl-azolyl derivatives of the formula ##STR1## in which Az is 1,2,4-triazolyl or imidazolyl, X is optionally substituted phenyl or alkyl, R is ##STR2## R1 is hydrogen or halogen, R2 is halogen, R3 is alkylt... | 11/11/1986 |
| 4619923 | Metal protoporphyrins in the control of tryptophan metabolism Method of controlling the rate of tryptophan metabolism in the liver of humans by parenteral administration of tin or chromium protoporphyrin to increase the rate, and the administration of cobalt protoporphyrin to decrease the rate.... | 10/28/1986 |
| 4587239 | 1-azolyl-3-pyrazolyl-2-propanol fungicides 1-Azolyl-3-pyrazolyl-2-propanol derivatives of the general formula ##STR1## in which Az represents 1,2,4-triazol-1-yl, imidazol-1-yl or pyrazol-1-yl and R represents alkyl, alkenyl, alkinyl, optionally substituted phenyl, optionally substituted pheny... | 05/06/1986 |
| 4584308 | Substituted hydroxyalkyl-azole fungicidal agents, their preparation and their use A method of combating fungi which comprises to such fungi or to a fungus habitat a fungicidally effective amount of a substituted hydroxyalkyl-azole of the formula ##STR1## in which R1 is optionally substituted phenyl, --O-phenyl, --S-phen... | 04/22/1986 |
| 4582828 | Fungicidal 5-oxo-4-trisubstituted tin-1,3,4-oxadiazolines Compounds of the formula: ##STR1## wherein R is aryl of 6 to 10 carbon atoms; substituted aryl substituted with 1 to 5 substituents selected from halogen, nitro, lower alkyl of 1 to 6 carbon atoms, lower alkoxy of 1 to 6 carbon atoms, lower alkylthio... | 04/15/1986 |
| 4565812 | Fungicidal tin salts of thienyl and furyl hydroxamic acids, compositions, and method of use therefor Compounds of the formula: ##STR1## wherein Z is sulfur or oxygen; R is alkyl of 1 to 7 carbon atoms; R1 is aryl of 6 to 10 carbon atoms, lower alkyl of 1 to 6 carbon atoms or cycloalkyl of 3 to 8 carbons, all optionally substituted with 1 ... | 01/21/1986 |
| 4563447 | Combating fungi with 4-piperidino methyl-1,3-dioxolanes Substituted 4-piperidinomethyl-1,3-dioxolanes of the formula ##STR1## in which R1 is tetrahydronaphthyl, decahydronaphthyl, optionally substituted naphthyl, optionally substituted cycloalkyl or cycloalkenyl, optionally substituted phenyl, ... | 01/07/1986 |
| 4549900 | Combating fungi with substituted 1-azolyl-butan-2-ones and -2-ols Substituted 1-azolyl-but-2-ones and -2-ols of the formula ##STR1## in which B is --CO-- or --CH(OH)-- Az represents a 1,2,4-triazol-1-yl or -4-yl or imidazol-1-yl radical, R1 represents a hydrogen atom, an alkyl, alkenyl, alkinyl, optionally su... | 10/29/1985 |
| 4548945 | Fungicidally active substituted 1-hydroxyethyl-triazolyl derivatives Substituted 1-hydroxyethyl-triazole derivatives of the formula ##STR1## in which R represents optionally substituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl, X represents the grouping --OCH2 --, --SCH2 | 10/22/1985 |
| 4522825 | Acaricide compositions employing synergistic mixtures of 1-decyloxy-4-(7-oxa-4-octinyl)-oxy-benzene and propargite There are described mixtures with a synergistic action of two acaricide compounds as well as their use in suitable compositions in the fight against mite infestations on useful plants.... | 06/11/1985 |
| 4517194 | Azolylmandelic acid derivatives and use thereof for controlling microorganisms The invention relates to microbicidal mandelic acid derivatives of the formula I ##STR1## wherein X is the bridge member --CH.dbd. or --N.dbd., Ar is a phenyl, diphenyl or naphthyl group, R1, R2 and R3 independently of one... | 05/14/1985 |
| 4497806 | Triorganotin compounds, antifungal and antibacterial compositions containing same, and method of using same Antifungal and antibacterial compounds, compositions containing the same, and method of using the same comprising triorganotin 5-nitro-2-furoates represented by Formula (I) ##STR1## wherein R, which may be the same or different, is an alkyl group, a ... | 02/05/1985 |
| 4497647 | Triazolylalkenes as fungicides and plant growth regulants The invention relates to novel azolyl-olefin derivatives of the general formula I ##STR1## wherein R1 is an azolyl group, R2 is C1 -C12 alkyl, C3 -C8 cycloalkyl, C1 -C4... | 02/05/1985 |