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Patent No. 5687752

Dining Table Having Integral Dishwasher

A space-saving dishwasher, which may be installed within a counter top or table, having a dish-carrying rack that is vertically shiftable through the open top of the dishwasher for facilitating loading and unloading of the dishes.

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Class 514/183 - Heterocyclic carbon compounds containing a hetero ring having chalcogen (i.e., O,S,Se or Te) or nitrogen as the only ring hetero atoms DOAI


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter which includes a compound containing a ring
No. of patents: 1731
Last issue date: 03/16/2010


1                      
NumberTitleIssue Date
7678783Macrocyclic tertiary amine beta-secretase inhibitors for the treatment of alzheimer's disease
The present invention is directed to macrocyclic tertiary amine compounds represented by general formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the be...
03/16/2010
7678784Oxime-containing macrocyclic acyl guanidines as β-secretase inhibitors
There is provided a series of oxime-containing macrocyclic acyl guanidines of Formula (I) or a stereoisomer; or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, R4, ...
03/16/2010
7662809Tetracyclic indole derivatives as antiviral agents
The present invention relates to tetracyclic indole compounds of formula (I); wherein R1, R2, R14, R15, A, Ar, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprisi...
02/16/2010
7662807Sulphonated meso-tetraphenyl chlorins
The present invention provides photosensitizing agents obtained by reducing a single double bond in the porphyrin macrocycle of a sulphonated meso-tetraphenylporphyrin, preferably a disulphonated meso-tetraphenylporphyrin such as TPPS2a. The resulting sul...
02/16/2010
7662808Diazabicyclic aryl derivatives as cholinergic receptor modulators
This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the in...
02/16/2010
7655643Antibacterial macrocycles with substituted biphenyl
The invention relates to antibacterial macrocycles with substituted biphenyl and processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the production of medicaments for the treatment and/or prophylaxis of dise...
02/02/2010
76556423-cyano-quinoline derivatives with antiproliferative activity
The present invention concerns the compounds of formula the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Z represents NH; Y...
02/02/2010
7652003Macrocyclic β-secretase inhibitors
Disclosed are novel compounds of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, n and X are as defined in the sp...
01/26/2010
764897617-allylamino-17-demethoxygeldanamycin polymorphs and formulations
Polymorphs and pharmaceutical formulations of 17-allylamino-17-demethoxygeldanamycin (17-AAG). ...
01/19/2010
7648975Macrocyclic quinazoline derivatives as antiproliferative agents
The present invention concerns the compounds of formula (I) the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein Z represents O, CH2, NH or S; in particular Z represents NH; Y represent...
01/19/2010
7618957Perfluoroalkyl-containing complexes, process for their production as well as their use
The invention relates to the subjects that are characterized in the claims, namely perfluoroalkyl-containing metal complexes with nitrogen-containing radicals of general formula I, process for their production and their use in NMR and x-ray diagnosis, radiodiagnosis...
11/17/2009
7615548Method to inhibit ischemia and reperfusion injury
Methods of treating or inhibiting ischemia and reperfusion injury are provided. ...
11/10/2009
7612056Substituted diaza-spiro-[4.5]-decane derivatives and their use as neurokinin antagonists
This invention concerns substituted diaza-spiro-[4.5]-decane derivatives having neurokinin antagonistic activity, in particular NK1 antagonistic activity, a combined NK1/NK2 antagonistic activity, a combined NK1/NK3
11/03/2009
7612054Dibenzo[b,f]oxepine-10-carboxamides and pharmaceutical uses thereof
The present invention pertains to novel dibenzo[b,f]oxepine-10-carboxamides compound to a process for the preparation of such compounds of formula I, their use as a pharmaceuticals, especially in the treatment of neurological and vascular disorders related to beta-a...
11/03/2009
7612055Macrocyclic lactams and pharmaceutical use thereof
The present invention relates to novel macrocyclic compounds of the formula wherein R1, R2, R3, U, V, W, X, Y, Z and n are as defined in the specification, the number of ring atoms included ...
11/03/2009
7608613Analogs of benzoquinone-containing ansamycins and methods of use thereof
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where...
10/27/2009
7608611Hsp90 inhibitors, methods of making and uses therefor
The invention provides purified 18,21-didehydro-18,21-dideoxo-18,21-dihydroxy-geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents that are useful for the treatment and/or the amelioration of s...
10/27/2009
7608612Radiosensitizer formulations and methods for use
The present invention provides radiosensitizer compositions, in controlled-release formulations or other acceptable formulations, particularly nitrohistidine radiosensitizer compositions, which may be administered by any suitable means including oral, intravenous, a...
10/27/2009
7601709Macrocyclic hepatitis C serine protease inhibitors
The present invention relates to compounds of Formula I, II or Ill, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: wherein W is a substituted or unsubstituted heterocyclic ring system. The compounds inhibi...
10/13/2009
7595310Glucuronate salt of a piperazine compound
The present invention provides a salt form, and compositions thereof, useful as a modulator of one or more GPCRs and which exhibits desirable characteristics for the same. The present invention also provides methods for preparing said salt form. ...
09/29/2009
7592330Methods and compositions for preserving the viability of photoreceptor cells
Provided are methods and compositions for maintaining the viability of photoreceptor cells following retinal detachment. The viability of photoreceptor cells can be preserved by administering a neuroprotective agent, for example, a substance capable of suppressing e...
09/22/2009
7592331Macrocyclic factor VIIa inhibitors useful as anticoagulants
The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, L, M, W, Z, R1
09/22/2009
7589083Compounds and compositions to control abnormal cell growth
A class of compounds commonly containing a trialkylammonium group have been synthesized and characterized as anticancer compounds. A representative of this class, N,N-diethyl-N-methyl-2-[(9-oxo-9H-thioxanthen-2-yl)methoxy]ethanaminium iodide (CCDTHT) was shown in va...
09/15/2009
7579336Pharmaceutical composition comprising temozolomide ester
The present invention discloses general formula I of Temozolomide-8-carboxylate compounds, the process for preparation, pharmaceutical compositions comprising the compounds and the use of the compounds and pharmaceutical compositions for the manufacture of an antitu...
08/25/2009
7579337Analogs of benzoquinone-containing ansamycins and methods of use thereof
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where...
08/25/2009
7576074Receptor-type kinase modulators and methods of use
The present invention provides compounds for modulating receptor kinase activity, particularly ephrin and EGFR, and methods of treating diseases mediated by receptor kinase activity utilizing the compounds and pharmaceutical compositions thereof. Diseases mediated b...
08/18/2009
7572798Combi-molecules having signal transduction inhibitory properties and DNA damaging properties
The present invention relates to a series of new chemical agents that demonstrate anti-tumor activity. More particularly, the present invention relates to molecules, referred to as “combi-molecules”, that combine two major mechanisms of anti-tumor action. A comb...
08/11/2009
7566706Analogs of benzoquinone-containing ansamycins and methods of use thereof
The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where...
07/28/2009
7560449Methods and therapeutic combinations for the treatment of demyelination
The present invention provides methods for treating demyelination and associated conditions by administering at least one sterol absorption inhibitor and compositions, therapeutic combinations and methods including: (a) at least one sterol absorption inhibitor; and ...
07/14/2009
7553832Methods and compositions for specific inhibition of protein splicing by small molecules
The present invention relates to compositions (i.e., various organic small molecules as exemplified herein) and methods for the inhibition of protein splicing and especially relates to the inhibition of protein autosplicing of intein-containing proteins. Additionall...
06/30/2009
7553831Compounds to treat Alzheimer's disease
The present invention is disubstituted amines of formula (I) and disubstituted amines of formula (II) useful in treating Alzheimer's disease and other similar diseases. ...
06/30/2009
7547688Methods for treatment of nocturia
A method for the treatment of nocturia which consists of administering to a mammal in need of such treatment a therapeutically effective amount of a nonsteroidal anti-inflammatory drug consisting of loxoprofen or a pharmacologically acceptable salt thereof, wherein ...
06/16/2009
7544675Chemical compounds with dual activity, processes for their preparation and pharmaceutical compositions
The present invention concerns chemical compounds combining affinity and antagonism against the human m3 muscarinic receptor with activity as selective phosphodiesterase IV (PDE IV) inhibitors, processes for preparing them, pharmaceutical compositions containing the...
06/09/2009
7531529Imidazole derivatives
The present invention relates to imidazole derivatives of formula I wherein R1, R2, R3 and R4 are described hereinabove. These compounds can be used in the treatment or prevention...
05/12/2009
75281241,3-dihydro-2H-indol-2-one derivative
A 1,3-dihydro-2H-indol-2-one derivative expressed by Formula 1 (wherein R1 is a halogen atom, a C1 to C4 alkyl group, etc., and R2 is a hydrogen atom, a halogen atom, etc., or R2 is in the 6-position of the indo...
05/05/2009
7524837Benzotriazapinone salts and methods for using same
This invention relates to pharmaceutically acceptable salts of compounds of formula (I) Such salts are useful, for example, for the treatment of gastrin related disorders. ...
04/28/2009
7507727Substituted quinobenzoxazine analogs and methods of using thereof
The present invention relates to quinobenzoxazines analogs having the general formula: and pharmaceutically acceptable salts, esters and prodrugs thereof; wherein V, A, X, Z, W, U a...
03/24/2009
7507726Peptide deformylase inhibitors
Novel PDF inhibitors and novel methods for their use are provided. ...
03/24/2009
7494986Cycloalkylamine derivatives as NK-1/SSRI antagonists
The present disclosure relates to chemical compounds and their use in human therapy. A specific embodiment relates to compounds of Formula (I) or an isomer, a pharmaceutically acceptable salt or solvate thereof and pharmaceutically acceptable formulations comprising...
02/24/2009
7485630Neuroprotective macrocyclic compounds and methods for their use
Embodiments of this invention provide novel peptidomimetics that contain a macrocycle. Such compounds are neuroprotective and have utility as therapeutic agents for treatment of diseases, injuries and other conditions characterised by neuronal degeneration and/or de...
02/03/2009
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