Class 436/829 - LIPOSOMES (E.G., ENCAPSULATION, ETC.)

Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Art collection relating to the formation of lipsomes containing
No. of patents: 396
Last issue date: 09/02/2008

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Number	Title	Issue Date
7419796	Method of making a test device The present invention relates to a method for making a test device for detecting or quantifying an analyte in a sample. This method involves contacting a membrane with a mixture including derivatized, marker-loaded liposomes, and substantially dehydrating the mixtur...	09/02/2008
7208322	Sensor surfaces for detecting analytes The present invention provides a sensor surface comprising: a substrate coated with a free electron metal; and a matrix layer disposed on the free electron metal, wherein the matrix layer comprises an organic compound having a boronic acid complexing moiety. The mat...	04/24/2007
7179659	Sensor surfaces for detecting analytes and methods of use The present invention provides a method for detecting an analyte, comprising providing a sensor comprising a substrate coated with a free electron metal, a matrix layer disposed on the free electron metal, the matrix layer comprising an organic compound, wherein the...	02/20/2007
7049152	Color and shape changing polymeric ribbons and sheets The present invention herein provides the design, synthesis and characterization of compositions comprising asymmetric bolaamphiphilic lipids that form extended polymeric ribbons and wide sheets. These compositions may be doped, or interspersed, with various compoun...	05/23/2006
7005132	Prodrug compositions and drug delivery methods using synthetic receptors The present invention provides prodrug and multiprodrug complexes comprising drugs specifically bound to synthetic receptors in such a manner that active drug becomes available only in the presence of a targeted pathophysiologic receptor. Methods for preparation end...	02/28/2006
6984528	Method for detecting an analyte by fluorescence Two-dimensional and three-dimensional arrays of a polydiacetylene backbone having a substrate incorporated are used in chemical sensing methods to detect the interaction of an analyte with the substrate by monitoring the change in the fluorescence of the array. ...	01/10/2006
6962747	Self-assembled lipid bilayer materials The present invention is a self-assembling material comprised of stacks of lipid bilayers formed in a columnar structure, where the assembly process is mediated and regulated by chemical recognition events. The material, through the chemical recognition interactions...	11/08/2005
6939721	Fluorescence immunoassays using organo-metallic complexes for energy transfer The invention includes a composition of matter and method that utilizes energy transfer between one or more donor and acceptor molecules. The composition of matter includes an encapsulation vesicle having a matrix, a surface coating of an organo-metallic complex and...	09/06/2005
6858224	Method of preventing aggregation of a lipid:nucleic acid complex Particle aggregation of lipid:nucleic acid complex particles is prevented by incorporating a non-cationic lipid into lipid:nucleic acid complex particles containing a cationic lipid and a nucleic acid polymer. The non-cationic lipid is a polyethylene glycol-based po...	02/22/2005
6815432	Methods for encapsulating plasmids in lipid bilayers Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are described. The particles can be formed using either detergent dialysis methods or methods which utilize organic solvents. The particles are typically 65-85 nm, fully encapsula...	11/09/2004
6777193	Methods for diagnostic and/or treatment of antiphospholipids antibodies-related diseases, and devices Methods for detecting anti-lipidic particles antibodies and lipidic particles in cellular membranes for the diagnosis of diseases associated to the antiphospholipid syndrome are disclosed. Kits or sets to put these methods of diagnosis into practice are also disclos...	08/17/2004
6743585	Methods for preparing conjugates Methods are disclosed for conjugating one moiety to another moiety. In the method the moieties are reacted with one another in a protic solvent. Reaction between the moieties and the protic solvent during the conjugating is negligible or reversible. A stable bond is...	06/01/2004
6743638	Detection system using liposomes and signal modification A process for detecting an analyte which process comprises (a) contacting a sample suspected of containing said analyte with a containment means comprising a barrier which separates signal generating reagents from said sample, in the presence of an element which int...	06/01/2004
6720192	Screening for analytes using labeled receptors A method for assaying an analyte in a sample. The method comprising the steps of a) contacting the sample with material comprising a receptor which is present in a liposome and which liposome comprises a detectable functionality, said contact occurring under conditi...	04/13/2004
6706861	Reconstitution of purified membrane proteins into preformed liposomes The present application relates to a method of making liposomes having membrane proteins incorporated therein, the method comprising: providing the membrane protein in solution; providing a solution of preformed liposomes; and incubating the mixture. Prior to the st...	03/16/2004
6582970	Simple immunochemical semi-quantitative assay method and apparatus The present invention relates to a simple immunochemical semi-quantitative assay method according to chromatography, which comprises trapping a certain amount of an analyte in a sample with a predetermined amount of a fixed antibody for the analyte before...	06/24/2003
6582928	Carbohydrate-directed cross-linking reagents The invention provides heterobifunctional cross-linking reagents and methods of using the cross-linking reagents. The cross-linking reagents of the invention combine a nucleophilic hydrazide residue with an electrophilic maleimide residue allowing couplin...	06/24/2003
6534484	Methods for encapsulating plasmids in lipid bilayers Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are described. The particles can be formed using either detergent dialysis methods or methods which utilize organic solvents. The particles are typically 65-85 nm, full...	03/18/2003
6495352	Sol-gel method for encapsulating molecules A method for encapsulating organic molecules, and in particular, biomolecules using sol-gel chemistry. A silica sol is prepared from an aqueous alkali metal silicate solution, such as a mixture of silicon dioxide and sodium or potassium oxide in water. Th...	12/17/2002
6485987	Sol-gel matrices for direct colorimetric detection of analytes The present invention relates to methods and compositions for the direct detection of analytes using color changes that occur in immobilized biopolymeric material in response to selective binding of analytes to their surface. In particular, the present in...	11/26/2002
6410696	Cyclosporin immunoassay A method of measuring the amount of cyclosporin in a sample suspected of containing cyclosporin is disclosed. A method of inactivating interfering cross-reactive material in an assay for measuring the amount of cyclosporin in a sample suspected of contain...	06/25/2002
6403117	Archaesomes, archaeosomes containing coenzyme Q10 and other types of liposomes containing coenzyme Q10 adjuvants and as delivery vehicles Novel archaeosome compositions and their use in vaccine formulations as adjuvants and/or delivery systems, to enhance the immune response to immunogens in an animal such as a human, are described. Another aspect relates to the use of these archaeosomes to...	06/11/2002
6391541	Apparatus for analyzing a fluid sample A cartridge for separating a desired analyte from a fluid sample has a sample flow path and a lysing chamber in the sample flow path. The lysing chamber contains at least one filter for capturing cells or viruses from the sample as the sample flows throug...	05/21/2002
6387397	Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery The present invention relates to targeted polymerized liposomes for oral and/or mucosal delivery of vaccines, allergens and therapeutics. In particular, the present invention relates to polymerized liposomes which have been modified on their surface to co...	05/14/2002
6352716	Steroidal liposomes Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to b...	03/05/2002
6350466	Targeted polymerized liposome diagnostic and treatment agents Polymerized liposome particles which are linked to a targeting agent and may also be linked to a contrast enhancement agent and/or linked to or encapsulating a treatment agent. The targeting imaging enhancement polymerized liposome particles interact with...	02/26/2002
6348213	Method for reversing age-related changes in heart muscle cells A method of-treating a relatively aged animal to reverse age-related changes in the lipid composition of organ and tissue cells, such as heart muscle cells, and the ability of the animal to withstand respiratory stress. A suspension of small unilamellar v...	02/19/2002
6322810	Materials and methods for making improved micelle compositions Provided are methods for preparing improved biologically active micelle and crystalline products comprising a biologically active amphipathic compound in association with a micelle or crystalline product. Methods for producing the micelle or crystalline p...	11/27/2001
6316024	Therapeutic liposome composition and method of preparation Reagents for use in preparing a therapeutic liposome composition sensitized to a target cell are described. The reagents include a liposomal composition composed of pre-formed liposomes having an entrapped therapeutic agent and a plurality of targeting co...	11/13/2001
6294191	N-acyl phosphatidylethanolamine-mediated liposomal drug delivery This invention provides liposomes containing one or more N-acylated phosphatidylethanolamines, such liposomes being useful for localizing the delivery of bioactive agents to cells....	09/25/2001
6284267	Amphiphilic materials and liposome formulations thereof Disclosed is a new structural class of amphiphilic molecules which incorporate a hydrophilic material or polymer attached, at spatially distinct sites, to at least two hydrophobic residues. Certain of the amphiphilic molecules comprise a plurality of hydr...	09/04/2001
6277652	Colorimetric sensor employing polydiacetylene membrane Disclosed is a colorimetric sensor comprising polydiacetylene membrane liposomes, a polydiacetylene membrane film or fine particles coated with a polydiacetylene membrane, in which the polydiacetylene membrane is incorporated with a protein having a reduc...	08/21/2001
6258528	Signal amplification method The present invention relates to a method for the amplification of or creation of A signalling event for detection of a probe which reacts with a test substance, the method comprising causing the test substance to react with the probe and identifying the ...	07/10/2001
6258378	Delivery of biologically active substance to target sites in the body of patients The invention concerns a method for administering bioactive substances to patients at selected sites in the body and remotely promoting delivery of said media to selected organs or tissues in the body. The method comprises providing an administrable formu...	07/10/2001
6251581	Assay method utilizing induced luminescence Methods are disclosed for determining an analyte in a medium suspected of containing the analyte. One method comprises treating a medium suspected of containing an analyte under conditions such that the analyte, if present, causes a photosensitizer and a ...	06/26/2001
6248353	Reconstitution of purified membrane proteins into preformed liposomes The present application relates to a method of making liposomes having membrane proteins incorporated therein, the method comprising: providing the membrane protein in solution; providing a solution of preformed liposomes; and incubating the mixture. Prio...	06/19/2001
6248596	Liposome-enhanced immunoassay and test device A test device for detecting or determining an analyte in a test solution includes an absorbent material having separate contact, competitive binding, and measurement portions. The contact portion is positioned for contact with and uptake of the test solut...	06/19/2001
6235535	Fluorescent energy transfer ligand interaction assay on a lipid film This invention relates to a fluorescence-based immunoassay method for the detection of an analyte, or for the measurement of its concentration in a biological sample. The method is based on the ability of a multivalent analyte to induce aggregation of rec...	05/22/2001
6221386	Use of virulence factors of pathogens to improve liposomal delivery of therapeutic agents Liposome encapsulated antibiotic therapy has limited application against infectious organisms, which can sequester in non-phagocytic cells. Virulence factors of these infectious organisms, for example bacterial components, when used in the formulation of ...	04/24/2001
6207185	Method for inducing a systemic immune response to an HIV antigen A method is provided for inducing a systemic immune response to an antigen selected from inactivated HIV I and HIV II antigens in a mammal. The method comprises orally administering lyophilized multilaminar liposomes containing the antigen. The liposomes ...	03/27/2001

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Class 436/829 - LIPOSOMES (E.G., ENCAPSULATION, ETC.)