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Class 436/69 - CLOTTING OR CLOTTING FACTOR LEVEL TESTS


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Processes or compositions , for performing clotting tests
No. of patents: 531
Last issue date: 05/21/2013


1                      
NumberTitleIssue Date
8445287Method and apparatus for determining anticoagulant therapy factors
Methods and apparatus are disclosed for determining new anticoagulant therapy factors for monitoring oral anticoagulant therapy to help prevent excessive bleeding or deleterious blood clots that might otherwise occur before, during or after surgery. The inventive me...
05/21/2013
8435792Methods and compositions for treating bleeding disorders
Aspects of the invention include methods for enhancing blood coagulation in a subject. In practicing methods according to certain embodiments, an amount of a non-anticoagulant sulfated polysaccharide (NASP) is administered to a subject to enhance blood coagulation i...
05/07/2013
8357539Activated partial thromboplastin time measuring reagent, activated partial thromboplastin time measuring method, and determination method for determining presence or absence of blood coagulation inhibitor
An activated partial thromboplastin time measuring reagent, including a first reagent containing a phospholipid and an activator and a second reagent containing a herparin neutralizer and a calcium salt is disclosed. An activated partial thromboplastin time measurin...
01/22/2013
8236568Method for analyzing hemostasis
A method and device for blood hemostasis analysis is disclosed. A blood sample is displaced to reach a resonant state. The resonant frequency of the blood sample is determined before, during and after a hemostasis process. The changes in the resonant frequency of th...
08/07/2012
8088624Method of detecting thrombosis by measuring von Willenbrand factor-cleaving protease
A method of detecting thrombosis or the degree of thrombophilia by measuring a von Willebrand factor cleaving protease, and a kit for detecting thrombosis or the degree of thrombophilia, comprising an antibody or a fragment thereof specifically binding to a von Will...
01/03/2012
8076144Protocol for risk stratification of ischemic events and optimized individualized treatment
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis ...
12/13/2011
8058073Immunodiagnostic test cards having indicating indicia
An immunodiagnostic test card includes a plurality of transparent chambers wherein each chamber includes a quantity of testing material that combines with a patient sample, when mixed, to produce an agglutination reaction. A plurality of indicia are disposed to aid ...
11/15/2011
8008086Protocol for monitoring direct thrombin inhibition
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis ...
08/30/2011
7977106Method for assaying coagulation in fluid samples
This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively ...
07/12/2011
7947505Method for testing efficacy of antithrombotic agent
The present invention provides a method for testing quickly and easily the manner in which an antithrombotic agent inhibits the acceleration of blood coagulation when a platelet agonist causes acceleration of blood coagulation. The invention is a test method wherein...
05/24/2011
7939329Protocol for risk stratification of ischemic events and optimized individualized treatment
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis ...
05/10/2011
7923256Method for assaying coagulation in fluid samples
This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively ...
04/12/2011
7923255Method of detecting platelet thrombosis or organ failure
A method of detecting platelet thrombosis or organ failure in a patient suffering from disseminated intravascular coagulation (DIC) or systemic inflammatory response syndrome (SIRS), comprising analyzing a von Willebrand factor-cleaving protease and/or a cleaving fa...
04/12/2011
7915049Method for investigating the thrombocyte function of the blood
A method for investigating the thrombocyte function of the blood, and particularly of platelet aggregation, wherein the following steps are carried out: a) cross-flowing an aperture with blood or blood components; b) determining the active radius of the aperture dep...
03/29/2011
7906338Systems and methods for measuring fluid properties
A fluid property measurement system for measuring free stream particulates includes a fluid movement device positioned within a fluid container which is configured to cause fluid flow within the fluid container along a fluid flow path when a fluid is present. A cons...
03/15/2011
7892842Procedure for the determination of the activity of the protease which activates factor VII from protein solutions
The present application relates to procedures for the determination of the activity of the protease which activates factor VII, also known as factor VII activating protease or FSAP. The application also relates to a method of detecting whether an individual has incr...
02/22/2011
7879615Hemostasis analyzer and method
A method and device for blood hemostasis analysis is disclosed. A blood sample is displaced to reach a resonant state. The resonant frequency of the blood sample is determined before, during and after a hemostasis process. The changes in the resonant frequency of th...
02/01/2011
7867771Reagent for measuring clotting time and method for stabilizing tissue factor
The present invention provides a reagent for measuring clotting time including a nonionic surfactant, a nickel ion and a tissue factor. A method for stabilizing a tissue factor, and use of a nonionic surfactant and a nickel salt for stabilizing a tissue factor are a...
01/11/2011
7785891Device and methods for identifying and treating aspirin non-responsive patients
The present invention relates to methods and compositions for identifying and treating subjects in need of antithrombotic therapies but who are not responsive to aspirin. ...
08/31/2010
7767459Method for determining prothrombin time
A method for determining prothrombin time of a plasma or whole blood sample includes measuring prothrombin time for at least two different dilutions for a test sample to determine tmin or INRmin. The prothrombin time for at least two different ...
08/03/2010
7767458Method for determining coagulation activation and device for carrying out said method
A method is disclosed of assaying circulating microparticles contained in a sample of whole blood or blood plasma from a patient to determine the patient's ability to generate thrombin or Factor Xa as blood-clotting factors, wherein the circulating microparticles ar...
08/03/2010
7754489Protocol for risk stratification of ischemic events and optimized individualized treatment
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis ...
07/13/2010
7745223Device with novel and improved surface properties
To increase the adhesion strength of coagulated blood on a surface by increasing the surface interaction of blood-inherent components like fibrin/fibrinogen and thrombocytes it is described to treat the surface by exposing it to ionized atoms or molecules. The surfa...
06/29/2010
7745224Procedure for the standardization of coagulation tests
The present invention lies in the field of coagulation diagnosis and relates to a procedure for the standardization of coagulation tests, where calibrators are used to which a discrete standard coagulation time is assigned. The procedure is particularly suitable for...
06/29/2010
7741124Detection procedures for fibrinogen and/or fibrinogen derivatives
Described are determination procedures for fibrinogen and/or fibrinogen-derivatives by matrix-independent turbidimetry. In the FIFTA called procedure the fibrinogen activity is preferably determined in an undiluted sample by addition of thrombin and/or albumin, as w...
06/22/2010
7732213Method of evaluating patient hemostasis
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis ...
06/08/2010
7544514Method and system for determining platelet-mediated clot formation
The present subject matter concerns methods for determining platelet medicated clot formation. Specifically, the subject matter provides a method for determining platelet-medicated clot formation in a blood sample. The method may include obtaining sample of blood, a...
06/09/2009
7534620Method and device for monitoring platelet function
The invention provides a method of monitoring platelet function in a mammal by passing blood removed from the body of the mammal through a passageway to contact an obstruction or irregularity in the passageway to generate a platelet mass in the passageway, and monit...
05/19/2009
7521247Cartridge for monitoring the function of a device for testing blood platelet function, method for function monitoring, and use of a test fluid
A cartridge for monitoring the function of a device for blood platelet diagnosis has a housing which includes a test chamber and a holding chamber. A fluid volume of a test fluid is present inside the holding chamber. An air cushion is arranged above the fluid volum...
04/21/2009
7510879Detection procedures for fibrinogen and/or fibrinogen derivatives
Described are determination procedures for fibrinogen and/or fibrinogen-derivatives by matrix-independent turbidimetry. In the FIFTA called procedure the fibrinogen activity is preferably determined in an undiluted sample by addition of thrombin and/or albumin, as w...
03/31/2009
7439069Blood coagulation test cartridge, system, and method
A system and method for determining a coagulation time, e.g., thrombin time, PT, aPTT, and ACT, of a blood sample deposited in a test cartridge is disclosed. The test cartridge includes a blood receptacle that is open to the atmosphere into which a blood sample is t...
10/21/2008
7422905Blood coagulation test cartridge, system, and method
A system and method for determining a coagulation time, e.g., TT, PT, aPTT, and ACT, of a test sample deposited in a test cartridge is disclosed. A cartridge housing having upper and lower major sides and a minor sidewall encloses a test chamber having a test chambe...
09/09/2008
7399637Blood coagulation test cartridge, system, and method
A system and method for determining a coagulation time, e.g., TT, PT, aPTT, and ACT, of a blood test sample deposited in a test cartridge is disclosed. A cartridge housing having upper and lower major sides and a minor sidewall encloses a test chamber having a test ...
07/15/2008
7393690Systems and methods for measuring fluid properties
A method for measuring properties of a fluid including placing a quantity of fluid in a container; inducing flow in the fluid wherein the flow is substantially streamlined in at least a measuring region of the container by constricting flow, and wherein the fluid is...
07/01/2008
7387880Method for monitoring resting and activated platelets in unfixed blood samples
The amount of platelet surface proteins in a sample may be measured by collecting a sample containing platelets into a collection tube containing a platelet stabilizing composition, labeling the platelet surface protein and detecting by cytometry. ...
06/17/2008
7361306Device and method for measuring coagulation time and platelet activity
The present invention refers to a novel device for measuring coagulation time and platelet activity wherein the patient can measure his or her coagulation time and platelet activity without the aid of medical professionals due to the fact that this device is fully a...
04/22/2008
7357016Process and device for determining viscosity
A process and a device for determining the viscosity of a fluid are proposed. Very simple and accurate determination is enabled in that the magnetic particles in the fluid are set into vibration by a magnetic field which varies over time. A measurement of the amplit...
04/15/2008
7357916Method for creating a uniform vascular wound in zebrafish or zebrafish larva
Disclosed are improved methods for creating a uniform vascular wound in a zebrafish larva or zebrafish. The methods illustratively include subjecting a zebrafish larva to laser irradiation in an amount and for a period of time effective to cause a uniform vascular w...
04/15/2008
7358337Assay for low molecular weight heparin
A prothrombin time reagent for determination of low molecular weight heparin in frsh whole blood and in anti-coagulant treated blood is provided. The reagent is composed of recombinant animal tissue factor, and a mixture of synthetic phospholipids, which mixture inc...
04/15/2008
7358091Device and methods for identifying and treating aspirin non-responsive patients
The present invention relates to methods and compositions for identifying and treating subjects in need of antithrombotic therapies but who are not responsive to aspirin. ...
04/15/2008
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