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| Number | Title | Issue Date |
| 7678578 | Cell permeabilization and stabilization reagent and method of use A cell permeabilization and stabilization reagent and method of use are disclosed. The reagent contains a N-acyl sarcosine or a salt thereof, a pH adjusting agent to adjust pH of the reagent in a range from about 4 to about 6; and an aqueous medium; the reagent havi... | 03/16/2010 |
| 7592181 | Occult blood testing device A self-contained system for testing for the presence of occult blood in a specimen has been provided. The system includes a housing holding a test element and a container for releasing a developing medium onto the test element. The housing includes a base portion en... | 09/22/2009 |
| 7544513 | Hemoglobin assay for neonatal screening The present invention provides an assay, suitable for neonatal screening of hemoglobinopathies by quantitatively determining the presence of at least one pair of hemoglobin (Hb) variants, determining the ratio between the signals obtained from each variant; and, bas... | 06/09/2009 |
| 7541190 | Method of measurement of cellular hemoglobin A method of measuring cellular hemoglobin of a blood sample includes mixing a blood sample with a permeation reagent, and incubating the sample mixture to permeate cellular membrane of red blood cells and to cause hemoglobin aggregation within the cells; adding a ne... | 06/02/2009 |
| 7517691 | Device for and method of testing occult blood in feces The presence of occult blood in feces is detected using device including a liquid tight packet containing a sheet of absorbent material impregnated with a liquid solution that reacts with feces to produce a color change when blood is present. The packet is opened ma... | 04/14/2009 |
| 7449339 | Spectroscopic method and apparatus for total hemoglobin measurement A method and apparatus for measuring Tot-Hb in a sample are provided. The method involves collecting absorbance measurements of a sample using a spectroscopic apparatus that includes a first primary calibration algorithm for one of Oxy-Hb, “Oxy-Hb plus Deoxy-Hb”... | 11/11/2008 |
| 7427505 | Fecal occult blood testing device and method A specimen testing device having a first panel including a first aperture for receiving a first specimen and a second aperture for receiving a second specimen; a second panel; a sheet disposed between the first and second panels for receiving at least the first spec... | 09/23/2008 |
| 7374943 | Haemoglobin assay The invention provides a kit for a glycated haemoglobin assay, said kit comprising: a porous membrane capable of retaining precipitated haemoglobin; a first reagent comprising zinc ions in aqueous basic solution or comprising a water soluble zinc compound; a second ... | 05/20/2008 |
| 7374765 | Methods and compositions for diagnosis and treatment of iron misregulation diseases Methods and compositions are provided for the diagnosis and treatment of iron misregulation diseases, including HFE polypeptides, agonists, and antagonists, and transferrin receptor agonists and antagonists. ... | 05/20/2008 |
| 7361513 | Cellular controls for glycated hemoglobin Hb A1c Disclosed are cellular hemoglobin A1c (Hb A1c) normal and abnormal (high) controls for use in detecting Hb A1c levels. The present invention also relates to methods for generating cellular Hb A1c controls using red blood cells and methods for using the cellular cont... | 04/22/2008 |
| 7361510 | Methods of detection of iron deficiency New diagnostic indexes and the method of use for detection of iron deficiency have been disclosed. These include a logistic function of mean cell hemoglobin (MCH) and mean cell volume (MCV), and a logistic function of mean cell hemoglobin concentration (MCHC) and MC... | 04/22/2008 |
| 7361512 | Low hemoglobin concentration cell percentage and method of use in detection of iron deficiency A method of producing low hemoglobin concentration cell percentage (LHCC %) and the method of use for detection of iron deficiency have been disclosed. LHCC % is a sigmoid function of mean cell hemoglobin concentration (MCHC), which correlates linearly with hypochro... | 04/22/2008 |
| 7358327 | Assembled hematin, method for forming same and method for polymerizing aromatic monomers using same An assembled hematin is formed by depositing hematin on an electrically charged substrate in one or more layers alternating with one or more layers of polyelectrolyte, preferably a cationic polymer. In a method for polymerizing an aromatic monomer, the assembled hem... | 04/15/2008 |
| 7354732 | Method of assay with sulfonic acid compound and nitro compound A method for measuring an analyte in a sample by using a redox reaction is provided, which gives values with excellent reliability. Prior to the redox reaction, at least one of a sulfonic acid compound and a nitro compound is added to the sample to eliminate the inf... | 04/08/2008 |
| 7347617 | Mixing in microfluidic devices Mixing of liquids in a microfluidic device is accomplished by dispensing the liquids into a first chamber to produce combined liquid. The liquids are thereafter discharged through at least one capillary from the first chamber into a second chamber for complete mixin... | 03/25/2008 |
| 7344849 | Assay The present invention relates to assay methods for the determination of cobalamin or vitamin B12 in a body fluid and in particular to assay methods for the metabolically active pool of cobalamin, comprising contacting a cell free sample of a body fluid wi... | 03/18/2008 |
| 7344751 | Assembled hematin, method for forming same and method for polymerizing aromatic monomers using same An assembled hematin is formed by depositing hematin on an electrically charged substrate in one or more layers alternating with one or more layers of polyelectrolyte, preferably a cationic polymer. In a method for polymerizing an aromatic monomer, the assembled hem... | 03/18/2008 |
| 7338634 | Quantitative fecal examination apparatus A quantitative fecal examination apparatus includes a fecal collector removably mounted on a container base, having the fecal collector provided with a suction portion for sucking a fecal specimen into the collector and then the fecal specimen is disposed into the c... | 03/04/2008 |
| 7325837 | Self laminating specimen capture and containment assembly and recordation form combination The present invention is a specimen capture and collection form that utilizes a self laminating form assembly having first and second separable parts one of which is used in the collection, capture and retention of a sample of material to be analyzed and the other o... | 02/05/2008 |
| 7315767 | Impedance spectroscopy based systems and methods One aspect of the invention provides a device that non-invasively determines the concentration of a substance in a target. The device includes a first electrode, a measuring circuit, and a data processor. In one embodiment of the device, the first electrode can be e... | 01/01/2008 |
| 7314453 | Handheld diagnostic device with renewable biosensor A handheld diagnostic device having a test head and a handle is equipped with an open test channel having sensors and liquid reagent dispensing opening for the diagnostic testing of body fluids. The test channel can draw in fluid sample by capillary force and be clo... | 01/01/2008 |
| 7312087 | Devices and methods for biochip multiplexing The invention is directed to devices and methods that allow for simultaneous multiple biochip analysis. The method of analyzing the plurality of biochips includes inserting a first biochp into a first station of an analysis device, inserting a second biochip into a ... | 12/25/2007 |
| 7294312 | Test cartridge holder for blood samples Improved methods and apparatus that make more accurate and reduces risk of filling reaction chambers of cartridge cells with blood samples to conduct blood coagulation tests of the type employing the plunger technique are disclosed. A cartridge holder is provided th... | 11/13/2007 |
| 7294307 | Apparatus for pumping and directing fluids for hematology testing An apparatus is provided for hematology testing, which has a sensing unit defining a counting orifice for the flow of a blood sample through the counting orifice to analyze the blood sample, and a pump unit having three syringes. A first syringe is coupled in fluid ... | 11/13/2007 |
| 7288413 | Combined chemical and immunochemical fecal occult blood test Methods for testing a fecal sample for the presence of hemoglobin, comprising performing a chemical fecal occult blood test on the sample and then performing an immunochemical fecal occult blood test on a portion of the sample exposed to the chemical reagents used i... | 10/30/2007 |
| 7285196 | Methods and apparatus for making integrated-circuit wiring from copper, silver, gold, and other metals In recent years, copper wiring has emerged as a promising substitute for the aluminum wiring in integrated circuits, because copper offers lower electrical resistance and better reliability at smaller dimensions than aluminum. However, use of copper typically requir... | 10/23/2007 |
| 7282349 | Solvatochromatic bacterial detection Solvatochromic dyes are used herein to indicate the presence of bacteria by incorporating them into various substrates such as films, woven and nonwoven fabrics, paper towels, coform and airlaid materials and bonded carded webs. These dyes change color in response t... | 10/16/2007 |
| 7277019 | Universal colorimetric imaging array device An apparatus (10) is provided for detecting an atmospheric component. The apparatus, capable of being inserted into an electronic device (30) having an imager (36) and a processor, comprises a substrate; one or more calorimetric reagents (14 | 10/02/2007 |
| 7264776 | Sanitary and compact fecal occult blood collector A biological sample collection and test kit and a method of using the kit are disclosed in the application. The kit includes a swab, having a sample collection portion, a cover for covering the sample collection portion of the swab for hygienic purpose. Also disclos... | 09/04/2007 |
| 7261861 | Hemostasis analyzer and method A method and device for blood hemostasis analysis is disclosed. A blood sample is displaced to reach a resonant state. The resonant frequency of the blood sample is determined before, during and after a hemostasis process. The changes in the resonant frequency of th... | 08/28/2007 |
| 7262505 | Selective electroless-plated copper metallization Structures and methods are provided which include a selective electroless copper metallization. The present invention includes a novel methodology for forming copper vias on a substrate, including depositing a thin film seed layer of Palladium (Pd) or Copper (Cu) on... | 08/28/2007 |
| 7255611 | Connector A connector having a compact engagement structure providing a high retaining force is provided. A shoulder is provided on an inner wall of a housing for storing a contact. The shoulder is inclined so that a distal end thereof projects toward a first end of the housi... | 08/14/2007 |
| 7241627 | Wearable article with multi-level alert system A wearable article equipped with a multi-level alert system detects and emits signals corresponding to various abnormal levels of a substance in a mammalian extract. By providing different signals corresponding to multiple abnormal levels of the substance, the weare... | 07/10/2007 |
| 7235404 | Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement A cyanide-free lytic reagent composition and method of use for measuring the total hemoglobin concentration and white blood cells in a blood sample are disclosed. The lytic reagent composition includes a quaternary ammonium surfactant to lyse red blood cells and rel... | 06/26/2007 |
| 7235378 | Method of selectively determining glycated hemoglobin A method of determining glycated hemoglobin is provided, by which a ratio of the glycated hemoglobin in a sample can be determined accurately and easily. The ratio of glycated hemoglobin can be determined by degrading a glycated hemoglobin in a whole blood sample se... | 06/26/2007 |
| 7226790 | Method for measurement using sodium azide A method of measuring an analyte in a sample with excellent sensitivity using a redox reaction is provided. In this method, a reducing substance or an oxidizing substance derived from the analyte is measured in the presence of a tetrazolium compound and sodium azide... | 06/05/2007 |
| 7223604 | Methods and kits for the detection of erythrocytes Methods and kits useful in the detection of occult blood in biological samples and specimens, for example to screen for colorectal cancer or detect blood in samples ex vivo, e.g., at a crime scene. Also provided are methods useful in diagnosing whether a subject is ... | 05/29/2007 |
| 7217393 | Apparatus and method for process monitoring An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the r... | 05/15/2007 |
| 7202340 | No-modified hemoglobins and uses therefor Nitrosylhemoglobin can be produced by introducing gaseous NO into an aqueous solution of hemoglobin. It has been demonstrated that nitrosylhemoglobin in aqueous solution can be converted to SNO-hemoglobin upon introduction of oxygen to the solution, as is postulated... | 04/10/2007 |
| 7198955 | Method and apparatus for measurement of blood substitutes A method is disclosed whereby the concentration of a blood substitute, such as cross-linked hemoglobin, in a serum or plasma specimen is rapidly and accurately identified and quantified. The method further takes the measured concentration of the blood substitute and... | 04/03/2007 |