Bizarre Patents
Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
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| Number | Title | Issue Date |
| 7781229 | Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates New chemiluminescent compounds, stable in aqueous buffers, for use in biological assaying include acridanebased compounds and (1,2)-dioxetanes. Among the new acridanebased compounds are water-soluble acridanes, enhancer coupled acridanes, bis and trisacridanes as we... | 08/24/2010 |
| 7357915 | Method of imaging cell death in vivo A method of imaging apoptosis in vivo, using radiolabeled annexin, is described. ... | 04/15/2008 |
| 7342091 | Soluble cyclic analogues of β amyloid peptide The invention concerns a peptide having the biological activity of an inhibitor of amyloid formation and its diagnostic and medical use. ... | 03/11/2008 |
| 7341837 | Soluble analyte detection and amplification The present invention relates to a method of detection of a compound of interest that is present at low levels in a sample. In particular, the present invention relates to a method of detection of a compound of interest in solution by a nucleic acid-labelled binding... | 03/11/2008 |
| 7332355 | Method and compositions for the detection of protein glycosylation The invention provides methods and compositions for the rapid and sensitive detection of post-translationally modified proteins, and particularly of those with post-translational glycosylations. The methods can be used to detect O-GlcNAc post-translational modificat... | 02/19/2008 |
| 7291714 | Glycoprotein VI and uses thereof The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein VI, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression v... | 11/06/2007 |
| 7291476 | O-acetyltranferases A post-translational modification of a predetermined protein expressed by a cell is detected by specifically detecting an O-acetylation of a serine, threonine or tyrosine residue of the protein as an indication of the post-translational modification. The detection m... | 11/06/2007 |
| 7235370 | Site-specific aminoglycoside derivatives for use in immunodiagnostic assays A method of making a derivatized aminoglycoside includes reacting an aminoglycoside with at least 2 equivalents of a divalent metal ion in an aprotic solvent to complex two neighboring amino group and hydroxyl group pairs; reacting the non-complexed amino groups wit... | 06/26/2007 |
| 7229782 | Antibodies specific to multiple beta blockers and methods for their use The present invention is directed antibodies specific to multiple beta blockers, as well as immunogens used to produce the antibodies and immunoassay kits and methods for using the antibodies. ... | 06/12/2007 |
| 7195882 | Monoclonal antibodies specific for buprenorphine and metabolites thereof The present invention relates to monoclonal antibodies that specifically bind buprenorphine and/or at least one metabolic product thereof. The present invention further relates to buprenorphine metabolite conjugates for the production of monoclonal antibodies that s... | 03/27/2007 |
| 7186518 | Method and composition useful for determining FK 506 New derivatives of FK 506 are disclosed. These new derivatives and other derivatives that are useful for determining the levels of FK 506 in a sample are also provided as are assay procedures and kits for use in determining the levels of FK 506 or other macrophilin ... | 03/06/2007 |
| 7169907 | Derivatives, immunogens, and antibodies for detecting ecstasy-class drugs Compounds including haptens, intermediates, and immunogens that are useful in the production of antibodies specific for the methylenedioxy class of amphetamine derivatives are described. Antibodies specific for the methylenedioxy class of amphetamine derivatives, re... | 01/30/2007 |
| 7135296 | Elemental analysis of tagged biologically active materials Improved methods for the detection and quantitation of labeled biological materials in a sample using elemental spectroscopic detection are described. Element-labeled biologically active materials, comprising antibodies, antigens, growth factors, hormones, receptors... | 11/14/2006 |
| 7132269 | Coupling agents, the active intermediates and the conjugates thereof and the use of said conjugates in diagnostic methods The present invention concerns coupling agents having the following general formula: activated intermediates consisting of a coupling agent such as defined above with either a molecule having on its surface at le... | 11/07/2006 |
| 7132513 | Bifunctional chelating agent The invention concerns a ligand comprising wherein n is an integer from 1 to 5, X represents —NO2, —NH2, —NCS, —NHCOCH2-Z. NHCO—W—COCNHS, —NH-Q, —NHCS-Q, —NHCOCH2-Q, or —NHCO(CH2)m... | 11/07/2006 |
| 7115718 | Haptens, immunogens, antibodies and conjugates to 2-oxo-3-hydroxy-LSD The invention provides a hapten derivatized with a crosslinker at the nitrogen of the 8β-carboxamide of 2-oxo-3-hydroxy LSD. The invention also provides an immunogen comprising the aforementioned hapten coupled to an antigenicity-conferring carrier material; a conj... | 10/03/2006 |
| 7108985 | Methods and kits useful for the simplification of complex peptide mixtures Methods and reagents for obtaining simplified mixtures of peptides from a sample containing a number of peptides are disclosed. The simplified sample can be easier to analyze than the original peptide sample yet it is representative of all or nearly all of the prote... | 09/19/2006 |
| 7109310 | Method and kit for detecting, or determining the quantity of, metabolites of fentanyl and metabolites of fentanyl analogs The invention provides an immunogen comprising a hapten coupled to an antigenicity-conferring carrier material, a conjugate comprising the aforementioned hapten coupled to a labelling agent, as well as, antibodies raised against the aforementioned immunogen and capa... | 09/19/2006 |
| 7101549 | Glycoprotein VI and uses thereof The invention provides isolated nucleic acid molecules and polypeptide molecules that encode glycoprotein VI, a platelet membrane glycoprotein that is involved platelet-collagen interactions. The invention also provides antisense nucleic acid molecules, expression v... | 09/05/2006 |
| 7101719 | Support and method for cell based assays Disclosed is a method for the measurement of a cellular process, or for the measurement of the effect of a test compound on a cellular process, in one or more different populations of cells. The method comprises providing separate samples of one or more different po... | 09/05/2006 |
| 7101980 | Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes Compounds including haptens, intermediates, and immunogens that are useful in the production of antibodies specific for the methylenedioxy class of amphetamine derivatives are described. Antibodies specific for the methylenedioxy class of amphetamine derivatives, re... | 09/05/2006 |
| 7078495 | Monoclonal antibodies to tacrolimus and immunoassay methods for tacrolimus An IgG1 λ monoclonal antibody to the immunosuppressive drug tacrolimus has improved properties. In particular, this monoclonal antibody, designated 1H6, has reduced cross-reactivity to several tacrolimus metabolites. This antibody is suitable for perform... | 07/18/2006 |
| 7070941 | Methods and compositions for tagging via azido substrates The invention provides methods and compositions for azide tagging of biomolecules. In one embodiment of the invention, proteins are tagged by metabolic incorporation of prenylated azido-analog substrates. Examples of such analogs are azido farnesyl diphosphate and a... | 07/04/2006 |
| 7052915 | Selective labeling and isolation of phosphopeptides and applications to proteome analysis A method for selective labeling of phosphate groups in natural and synthetic oligomers and polymers in the presence of chemically related groups such as carboxylic acid groups. The method is specifically applicable to biological oligomers and polymers, including pho... | 05/30/2006 |
| 7045309 | 9-substituted adenine derivatives as prodrug regulators of cell and tissue function The present invention relates to 9-substituted adenine derivatives represented by formula (I) wherein W is selected from the group consisting of H, halogen, azido and amino group; X is selected from the group consistin... | 05/16/2006 |
| 7045310 | Redox reversible bipyridyl-osmium complex conjugates Novel bipyridyl-osmium complex conjugates and their use in electrochemical assays are described. The redox reversible-osmium complexes can be prepared to exhibit unique reversible redox potentials and can thus be used in combination with other electroactive redox re... | 05/16/2006 |
| 7045606 | Bifunctional chelating agent for actinium The invention concerns a ligand comprising (I) wherein n is an integer from 1 to 5 Y is CO2H or PO3H2T represents —X or -phenyl-X, wherein X represents NO2, NH2, NCS, NHCOCH2-Z, NHCO—W—COCNHS, —NH-Q, —NHCS-Q, —NHCOCH2-Q, or NHCO(CH2)m-Q where Q is a hapt... | 05/16/2006 |
| 6986994 | INGAP displacement assays An antibody is provided which specifically recognizes and binds to INGAP protein. The antibody is used in competitive binding assays for quantitation of INGAP in biological samples. The assay can be performed on a solid support or in a suspension. ... | 01/17/2006 |
| 6964872 | Immunoassay method When insoluble magnetic carrier particles are used in immunoassay, a method is provided which is suitable for saving labor and for treating a large number of samples within a short time while avoiding problems including difficulties in the stability of sensitized in... | 11/15/2005 |
| 6960653 | Method and kit for detecting, or determining the quantity of, beta-lactam penicillins The invention provides a hapten comprising a 6-[D-α-aminoacetamido] penicillin derivative crosslinked at the α-amino group with a substituted or unsubstituted phenyldicarbaldehyde. In addition, the invention provides an immunogen comprising the aforementioned hapt... | 11/01/2005 |
| 6946547 | Ecstasy-class analogs and use of same in detection of ecstasy-class compounds The present invention provides a system for the improved detection of ecstasy-class compounds in biological samples. New ecstasy-class analogs are provided for detection of such ecstasy-class drugs. These analogs are compounds, or salts thereof, of a 2-amino-methyle... | 09/20/2005 |
| 6936700 | Bridged aromatic substituted amine ligands with donor atoms The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hyd... | 08/30/2005 |
| 6921669 | Linker system for activating surfaces for bioconjugation The present invention relates to a linker system for activating surfaces for bioconjugation, and particularly to a linker system having a novel hydrophilic spacer group. The inventive linker system may be used for the construction of sensor chips or biochips for the... | 07/26/2005 |
| 6913936 | Immunological test kit comprising an immunologically invisible peg copolymer conjugated to one or more immunologically reactive substances A novel compound comprising an immunologically invisible polyethylene glycol copolymer is used to carry one or more immunologically reactive substances. The novel compounds may be used as part of kits for immunological assays. ... | 07/05/2005 |
| 6905886 | Preservative solutions This invention relates to preservative solutions for peptides, for example, parathyroid hormone, insulin-like growth factor binding protein 3 (IGFBP3), adrenocorticotropic hormone (ACTH) and mixtures thereof. Preferably, the peptides preserved by the solutions are n... | 06/14/2005 |
| 6878811 | Substance with antithrombotic activity and method for detecting glycokallidin A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric prot... | 04/12/2005 |
| 6844162 | Assays for TSH receptor autoantibodies A method and kit for monitoring autoantibodies to thyroid stimulating hormone (TSH) receptor in a sample of body fluid, which employs the steps of: (i) incubating TSH receptor with a sample of body fluid; (ii) reac... | 01/18/2005 |
| 6844166 | Recombinant reduced valency carbohydrate binding ligands The invention is based on the discovery of reduced valency carbohydrate binding ligands (CBLs) that can be used to to detect or quantitate (i.e., evaluate) carbohydrates in a sample. CBLs can be used with fluorescence resonance energy transfer (FRET) to evaluate fre... | 01/18/2005 |
| 6838552 | Diagnosis and management of infection caused by Chlamydia The present invention provides a unique approach for the diagnosis and management of infections by Chlamydia species, particularly C. pneumoniae. The invention is based, in part, upon the discovery that a combination of agents directed toward the various stag... | 01/04/2005 |
| 6794496 | Immunoassay for LSD and 2-oxo-3-hydroxy-LSD The present invention provides hapten derivatives useful for the preparation of antigens, antibodies and reagents for use in immunoassays for the detection of LSD and 2-oxo-3-hydroxy LSD. In the present invention, the 2-oxy LSD nucleus is derivatized out of the indo... | 09/21/2004 |
