Glam girl Heddy Lamar may have used her good looks to good effect on the silver screen, but she put her smarts to better use as an inventor. During World War II, she co-patented a frequency-switching system for torpedo guidance that was considered years ahead of its time.
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| Number | Title | Issue Date |
| 7790475 | Apparatuses and methods for reducing albumin in samples The present invention is directed to apparatuses and methods for reducing the content of albumin in serum, plasma and/or blood samples. The apparatuses comprise an insoluble support with a ligand attached thereto. According to certain embodiments of the invention, t... | 09/07/2010 |
| 7374936 | Method and means for site directed therapy The present invention relates to the field of site directed therapy. More specifically the invention relates to site directed radio therapy, and provides a method for production of radioconjugates and an apparatus for radioimmunotherapy. The method, conjugates and a... | 05/20/2008 |
| 7361480 | Method and means for detecting gluten-induced diseases The invention is directed to a method of detecting gluten-induced diseases such as e.g. celiac disease and dermatitis herpetiformis. Said diseases are indicated by the presence of autoantibodies against tissue transglutaminase tTG in the blood The test is carried ou... | 04/22/2008 |
| 7354776 | Method of processing and testing powdered samples using immunochromatographic strip tests A method and kit for processing and testing powdered samples are provided herein. The powdered sample is combined with a fluid to produce a slurry or liquid suspension, and the slurry is contacted with an immunochromatographic test strip containing detectable reagen... | 04/08/2008 |
| 7348185 | Method and apparatus for capturing target substance A method for capturing a target substance in a sample, comprising the steps of preparing particles capable of capturing the target substance in a dispersed state in a fluid, aggregating the particles, and allowing the particles to capture the target substance in the... | 03/25/2008 |
| 7341843 | toxin A peptides and methods of predicting and reducing immunoresistance to toxin therapy The present invention provides BoNT/A peptides as well as methods of predicting or determining immunoresistance to botulinum toxin therapy in an individual using BoNT/A peptides. ... | 03/11/2008 |
| 7312028 | Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity A simple easy to manufacture analytical device capable of performing membrane based immunoassays on batch of samples within 3 to 10 minutes wherein the method permits focused application of samples, costly labeled immunoassay and signal amplification reagents, said ... | 12/25/2007 |
| 7250308 | Capture assay utilising a particulate analyte Device (1) for assaying a particulate analyte, comprising (a) a receptacle (2) for receiving a suspension (5) of particulate analyte, and containing label (3) for the particulate analyte, and (b) a porous detection material (4) tha... | 07/31/2007 |
| 7241381 | Method and apparatus for detecting chemical binding The method for screening binding between a target binder and potential pharmaceutical chemicals involves sending a solution (preferably an aqueous solution) of the target binder through a conduit to a size exclusion filter, the target binder being too large to pass ... | 07/10/2007 |
| 7241626 | Isolation and confirmation of analytes from test devices Methods, articles, and kits for obtaining elevated concentrations of a substance from a sample that has become bound, for example by providing a positive test result in an immunoassay or other binding assay. The concentrated substance is optionally subjected to furt... | 07/10/2007 |
| 7241628 | Method for immobilizing conjugates in diagnostic tests The invention concerns a method for the detection of an analyte in a sample using analyte-specific conjugates which have at least one heterologous group for an analyte-independent binding to a control zone. The present invention additionally provides new conjugates ... | 07/10/2007 |
| 7238537 | Assays An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile... | 07/03/2007 |
| 7232690 | Method and device for detecting and isolating pharmacological compounds being contained in substance mixtures A process for isolating and/or identifying at least one active chemical substance from a mixture of active and inactive chemical substances, is characterized by the steps: a) adding a target to said mixture and forming a complex of... | 06/19/2007 |
| 7192784 | Method of measurement in chromatography A substantial amount of a marker reagent associated with a measurement is measured in a marker reagent measurement area, and the substantial amount of the marker reagent is reflected by a result obtained in a reaction result measurement area where a reaction with a ... | 03/20/2007 |
| 7176036 | Electroactive microspheres and methods Methods and devices for electrochemical detection of a specific binding pair member utilizing a microsphere with an incorporated electroactive marker, wherein a member of the specific binding pair to be detected is bound, directly or through one or more intermediate... | 02/13/2007 |
| 7169618 | Magnetic particles and methods of producing coated magnetic particles An improved method for separating materials is provided, using colloidal, magnetizable aggregates, optionally silanized, and coated with a one or more layers of novel polysaccharide derivatives. Materials separated by the aggregates of the invention include inorgani... | 01/30/2007 |
| RE39457 | Liquid specimen container and attachable testing modules A biological fluid collection container comprising a cup member, a lid assembly removably mounted to the cup member comprising a housing with a downwardly extending cylindrical skirt, a luer lock with a throughgoing bore extending from one side of the lid housing. A... | 01/02/2007 |
| 7157047 | Device for containing, reacting and measuring, and method of containing, reacting and measuring The invention relates to a device for containing, reacting and measuring, and a method of containing, reacting and measuring, and provides a device for containing, reacting and measuring, and a method of containing, reacting and measuring which is also able to effec... | 01/02/2007 |
| 7122314 | Methods for detecting vancomycin-resistant microorganisms and compositions therefor A method for detecting the presence of a vancomycin-resistant microorganism in a biological sample using a single chimeric probe in a cycling probe reaction. ... | 10/17/2006 |
| 7112281 | Underdrain for filtration membrane A device and method for removal of liquid from the downstream side of a membrane or a well, such as a well of a multiwell plate. More specifically, the present invention is directed to a wicking structure, which channels droplets of liquid away from a membrane in co... | 09/26/2006 |
| 7087389 | Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity A simple easy to manufacture analytical device capable of performing membrane based immunoassays on batch of samples within 3 to 10 minutes wherein the method permits focused application of samples, costly labeled immunoassay and signal amplification reagents, said ... | 08/08/2006 |
| 7071005 | Method and device for concentrating selected groups of microorganisms A method and device are described to concentrate target organisms from a mixture of organisms. Beads (1) made of material such as nylon, polystyrene or glass are coated with antibodies of specific microorganisms. The beads (1) are contained in an enclo... | 07/04/2006 |
| 7070941 | Methods and compositions for tagging via azido substrates The invention provides methods and compositions for azide tagging of biomolecules. In one embodiment of the invention, proteins are tagged by metabolic incorporation of prenylated azido-analog substrates. Examples of such analogs are azido farnesyl diphosphate and a... | 07/04/2006 |
| 7060505 | Assay device An assay device and method are provided which allow the determination of the presence or absence of at least one analyte in a test sample, while providing specific identification of the test subject. The assay device includes a reaction medium having at least one re... | 06/13/2006 |
| 7045342 | Diagnostic detection device and method The invention provides an improved test cell for detecting the presence of an analyte in a liquid sample. The device has an elongate casing defining a liquid sample inlet, a reservoir volume, a test volume, and a window through the casing at the test volume. Dispose... | 05/16/2006 |
| 6998273 | Collection device for lateral flow chromatography A device for collecting oral liquids includes a lateral flow chromatography strip having a collection pad for insertion into the mouth. The collection pad is separated from the remainder of the chromatography strip by a liquid impermeable removable barrier which pre... | 02/14/2006 |
| 6998246 | Method for immobilizing conjugates in diagnostic tests The invention concerns a method for the detection of an analyte in a sample using analyte-specific conjugates which have at least one heterologous group for an analyte-independent binding to a control zone. The present invention additionally provides new conjugates ... | 02/14/2006 |
| 6969616 | Enterotoxin adsorbent, method of adsorptive removal, and adsorption apparatus The present invention is directed to an enterotoxin adsorbent comprising a compound having a log P (P denotes a partition coefficient in an octanol-water system) value of not less than 2.50 as immobilized on a water-insoluble carrier. ... | 11/29/2005 |
| 6964872 | Immunoassay method When insoluble magnetic carrier particles are used in immunoassay, a method is provided which is suitable for saving labor and for treating a large number of samples within a short time while avoiding problems including difficulties in the stability of sensitized in... | 11/15/2005 |
| 6927068 | Rapid and non-invasive method to evaluate immunization status of a patient An assay method and kit for detecting the presence of a predesignated, target IgG antibody in a sample selected from one or more patient bodily fluids. The method comprises the following steps: (a) contacting the sample of one or more patient bodily fluids with a me... | 08/09/2005 |
| 6858439 | Compositions and methods for separation of moieties on chips The present invention recognizes that separation of components of a sample facilitate, and are often necessary for, sample analysis. Dielectrophoretic separation provides an efficient, reliable, nondisruptive, and automatable method for the separation of moieties in... | 02/22/2005 |
| RE38688 | Sheet-like diagnostic device A solid diagnostic device for the quantitative determination of substances of biological affinity in biological fluids is described. A process is also described in which the biological fluid is brought into contact with a specific functional sector of the device, th... | 01/18/2005 |
| 6841393 | Selective removal of contaminants from a surface using colored particles and articles having magnets A system and method for removing contaminants from a surface. The system is designed to use very small particles having means thereon which are capable of selectively binding to a contaminant or contaminants of interest. The particles may contain a dye to render the... | 01/11/2005 |
| 6818456 | Color contrast system for lateral flow immunoassay tests A lateral flow immunoassay device includes a membrane strip for enabling capillary migration of a sample therealong with a labeled reagent disposed on the membrane. The label reagent is formulated for suspension in the sample migrating therepast. A captive reagent i... | 11/16/2004 |
| 6811969 | Retentate chromatography—profiling with biospecific interaction adsorbents This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by d... | 11/02/2004 |
| 6770490 | Membrane immunobead assay for the detection of ciguatoxin and related polyether marine toxins An immunological test kit suitable for the rapid detection of ciguatoxin and related low molecular weight lipid polyether marine toxins in fish tissues in the field, home or laboratory. The test procedure utilizes a synthetic membrane laminated onto one end of a sol... | 08/03/2004 |
| 6770488 | Practical method and apparatus for analyte detection with colloidal particles A colloidal system for detection of a variety of analytes involves techniques which permit reconstitution of a desiccated substance such as for surface enhanced Raman spectroscopic analysis and multiple sensors at once, each having different spectra through the use ... | 08/03/2004 |
| 6767714 | Diagnostic detection device and method The invention provides an improved test cell for detecting the presence of an analyte in a liquid sample. The device has an elongate casing defining a liquid sample inlet, a reservoir volume, a test volume, and a window through the casing at the test volume. Dispose... | 07/27/2004 |
| 6753189 | Detection apparatus and method for the same A catcher, having an immunological epitope, is fixed to a detection zone of a spreading layer. A marker, capable of easy detection, has an inmmunological epitope. The marker and bispecific antibodies are soluble so that they can move on the spreading layer. The bisp... | 06/22/2004 |
| 6750031 | Displacement assay on a porous membrane Displacement assays, under non-equilibrium conditions, are performed by flowing a liquid sample through a membrane having binding elements with binding sites saturated with a labelled form of the analyte. Analyte in the sample displaces, under non-equilibrium condit... | 06/15/2004 |