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| Number | Title | Issue Date |
| 7429458 | Methods of using bioelastomers Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subjects. In ge... | 09/30/2008 |
| 7361480 | Method and means for detecting gluten-induced diseases The invention is directed to a method of detecting gluten-induced diseases such as e.g. celiac disease and dermatitis herpetiformis. Said diseases are indicated by the presence of autoantibodies against tissue transglutaminase tTG in the blood The test is carried ou... | 04/22/2008 |
| 7354733 | Method for sorting and separating living cells We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a... | 04/08/2008 |
| 7320893 | Lipoprotein fingerprinting methods using metal ion chelate salts Methods are disclosed which separate and identify lipoproteins in biological samples. An ultracentrifuge density gradient is used to separate lipoprotein fractions. The fractions are visualized, resulting in a lipoprotein profile. The fractions can be further analyz... | 01/22/2008 |
| 7241578 | Immunoassay method/equipment, biological component measurable toilet, anti-albumin monoclonal antibody, cell strain producing the same, and albumin detection kit The immunoassay method of this invention measures the content of a subject substance in a sample. The method includes the steps of: (a) preparing a mixed solution by mixing the sample and an antibody solution including a first monoclonal antibody and a second monocl... | 07/10/2007 |
| 7232690 | Method and device for detecting and isolating pharmacological compounds being contained in substance mixtures A process for isolating and/or identifying at least one active chemical substance from a mixture of active and inactive chemical substances, is characterized by the steps: a) adding a target to said mixture and forming a complex of... | 06/19/2007 |
| 7223546 | Method for measuring the amount of constituent contained in a specific lipoprotein There is provided a method and kit for measuring the amount of an objective constituent contained in a specific lipoprotein in a biological sample such as serum and plasma, specifically for measuring the amount of cholesterol contained in high density lipoprotein, w... | 05/29/2007 |
| 7166476 | Highly reproducible agglutination immunoassay method and reagents The present invention provides an agglutination immunoassay, wherein the agglutination of insoluble carrier particles such as latex are stabilized and uniformized to give good reproducibility, and a reagent therefor. In the agglutination immunoassay which comprises ... | 01/23/2007 |
| 7166477 | Muscle sample prepared for prion assay A method of preparing a sample of muscle tissue and of assaying the prepared sample to determine the presence of prions in the sample is disclosed. The muscle tissue is homogenized and mixed with a complexing agent which forms a complex with a higher specific gravit... | 01/23/2007 |
| 7151000 | Method of concentrating proteins from serum A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected to separation processing (e.g. centrifugation) to obtain serum. The ... | 12/19/2006 |
| 7018805 | α-Amylase assay and uses thereof This invention relates to methods and kits for measuring α-amylase activity in grain and plant products such as flour or stock. ... | 03/28/2006 |
| 6989240 | Method for detecting hemolysis This invention provides a method for determining the presence of hemolyzed erythrocytes in blood by detecting erythrocyte adenylate kinase in a serum sample from the blood. This invention also provides a method for diagnosing a hemolytic condition in a subject suspe... | 01/24/2006 |
| 6933109 | Rapid particle detection Methods and reagents for rapid purification and/or identification of particles in a liquid sample are described. The technique uses centrifugation to concentrate particles against a slanted surface having an agent specifically binding to the particles. This method i... | 08/23/2005 |
| 6887672 | Anti-equine Fc epsilon receptor alpha chain antibodies and methods to detect IgE The present invention relates to equine Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to ... | 05/03/2005 |
| 6828158 | Microparticle enhanced light scattering agglutination assay Reagents and the use of the reagents in a microparticle light scattering agglutination assay are disclosed. The reagents comprise a mixture of particles having relatively stronger light scattering properties and particles having relatively weak light scattering prop... | 12/07/2004 |
| 6773928 | Compositions and methods for enhancing bioassay performance Compositions of matter and methods for enhancing bioassay performance are disclosed. More particularly, the composition of matter comprises a molecularly compact polymer-ligand conjugate capable of self-orienting on a surface to improve the orientation of the ligand... | 08/10/2004 |
| 6770488 | Practical method and apparatus for analyte detection with colloidal particles A colloidal system for detection of a variety of analytes involves techniques which permit reconstitution of a desiccated substance such as for surface enhanced Raman spectroscopic analysis and multiple sensors at once, each having different spectra through the use ... | 08/03/2004 |
| 6762062 | Method of determining cholesterol and sensor applicable to the same The present disclosure relates to a method for determining cholesterol in low density lipoprotein comprising the steps of (a) measuring total cholesterol level in a sample containing at least high density lipoprotein, low density lipoprotein, very low density lipopr... | 07/13/2004 |
| 6753185 | Lipoprotein fingerprinting method Methods are disclosed which separate and identify lipoproteins in biological samples. An ultracentrifuge density gradient is used to separate lipoprotein fractions. The fractions are visualized, resulting in a lipoprotein profile. The fractions can be further analyz... | 06/22/2004 |
| 6723524 | Immunoassay method and kit An immunoassay, e.g. ELISA, method and kit for determining (preferably quantitatively) an analyte adsorbed at a surface or present in a liquid sample, comprising binding the analyte to a solid phase, attaching a marker to the analyte, and detecting marker attached t... | 04/20/2004 |
| 6689615 | Methods and devices for processing blood samples Approaches are described for separating plasma from whole blood samples and include the use of magnetically attractable particles associated with an agglutinating agent. The magnetically attractable particles bind the cellular components in a whole blood ... | 02/10/2004 |
| 6632603 | Non-captive substrate liquid phase immunoassay An immunoassay of a liquid biological specimen for a specific analyte is conducted by forming a test sample by contacting the specimen with: (1) a binding substance of a ligand, antiligand or receptor capable of binding the analyte and (2) a detector subs... | 10/14/2003 |
| 6589755 | Assay for quantifying arthritic conditions The present invention is drawn to a novel and newly discovered low molecular weight protein fragments that are degradation products of COMP and have a molecular weight of about 14-33 kilodaltons and polyclonal and monoclonal antibodies to the new COMP fra... | 07/08/2003 |
| 6582926 | Methods of using bioelastomers Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subj... | 06/24/2003 |
| 6514770 | Immunoassay Immunoassay methods for measuring the concentration of an analyte in a test specimen are described. The methods use an immunoreagent, where one of the analyte and the immunoreagent is an antigen, and the other of the analyte and the immunoreagent is an an... | 02/04/2003 |
| 6500628 | Nucleic acid molecules encoding human kinase and phosphatase homologues and uses therefor The invention provides isolated nucleic acids molecules, designated Kinase and Phosphatase nucleic acid molecules, which encode novel protein kinase and protein Phosphatase polypeptides. The invention also provides antisense nucleic acid molecules, recomb... | 12/31/2002 |
| 6416949 | Method of synthesizing diverse collections of oligomers A general stochastic method for synthesizing random oligomers can be used to synthesize compounds to screen for desired properties. The use of identification tags on the oligomers facilitates identification of oligomers with desired properties.... | 07/09/2002 |
| 6383819 | Method for determining cholesterol and sensor applicable to the same The present disclosure relates to a method for determining cholesterol in low density lipoprotein comprising the steps of (a) measuring total cholesterol level in a sample containing at least high density lipoprotein, low density lipoprotein, very low den... | 05/07/2002 |
| 6379918 | Composition, formulae, devices and methods for control of specificity and inclusivity of microorganisms containing closely related antigen epitopes Compositions, formulae, devices and methods for the detection of target microorganisms, such as by visual immunoprecipitate assay, enzyme linked immunoassay, chemiluminescence, immunoblotting, or similar detection technology, wherein detection requires th... | 04/30/2002 |
| 6362008 | Generic signalling mechanism for detection of analytes A generic signaling assay method comprising an affinity matrix for the detection of low molecular weight compositions is provided. A test sample is mixed with a pre-determined amount of a substance conjugated to at least two molecules of the target analyt... | 03/26/2002 |
| 6344336 | Assay apparatus The present invention relates to an assay apparatus for detecting a product in a sample. The assay apparatus comprises a fluid pathway with an input of the sample and an input for a reagent with a detectable moiety which transports the sample to a detecti... | 02/05/2002 |
| 6300142 | Device and apparatus for conducting an assay A apparatus for assaying glycated proteins and other analytes in biological samples such as blood, in which a sample is presented to the apparatus, includes an inlet port between moveable between first and second inlets, such that the inlet can be brought... | 10/09/2001 |
| 6248597 | Microparticle enhanced light scattering agglutination assay A microparticle light scattering agglutination assay is disclosed. The assay comprises a mixture of particles having strong light scattering properties with particles having weak light scattering properties. The particles having strong light scattering pr... | 06/19/2001 |
| 6210975 | Process for determining a bindable analyte via immune precipitation and reagent therefor The invention involves methods for determining analytes, and reagents for use in these methods. The methods and reagents use one or both of a polyvinyl/pyrolidone with a molecular weight of at least 360,000, and a polyethylene glycol with molecular weight... | 04/03/2001 |
| 6203997 | Quantitation of analytes in whole blood The invention relates to a method for quantitating the level of a preselected analyte in a sample of blood of a human or animal patient by incubating the test sample with an antibody specific to the analyte to form an immunocomplex, which then interacts w... | 03/20/2001 |
| 6166187 | Method of concentrating prion proteins in blood samples A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected to separation processing (e.g. centrifugation) to obtain ... | 12/26/2000 |
| 6159683 | Method of determining stage of sepsis The invention relates to a method for staging sepsis in a patient by concurrently measuring in a sample of the patient's blood four parameters which are indicative of the stage of sepsis: 1) the level of microbial product level in the blood; 2) the level ... | 12/12/2000 |
| 6132953 | Combinatorial synthesis on soluble polyvalent supports having a discrete architecture The present invention is directed to the use of a soluble polyvalent support for the preparation of combinatorial libraries of compounds. The resultant combinatorial libraries are useful in screening for biologically active moieties in the drug discovery ... | 10/17/2000 |
| 6124139 | Method and apparatus for indirect agglutination immunoassay A method of indirect agglutination immunoassay includes, allowing particles of a reagent for immunoassay to precipitate in bottoms of at least one well, inclining the well at a specified angle to form a precipitation pattern due to a flow of the particles... | 09/26/2000 |
| 6121055 | Methods and devices for conducting specific binding assays The invention provides methods for separating bound label from unbound label within an assay mixture, for predispensing assay reactants in self-contained assay vessels, as well as for detecting the presence and/or amount of an analyte within a fluid sampl... | 09/19/2000 |