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Patent No. 6049912

Mountable Printable Placard With Headband

A resilient headband in a shape for being mounted on the head of the user. The headband is equipped with a longitudinal slotted member for holding a placard.

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Class 436/532 - Antigen or antibody attached to a carrier via bridging agent


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Subject matter wherein the Ag or Ab is bonded to the polymeric
No. of patents: 584
Last issue date: 10/18/2011


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NumberTitleIssue Date
8039273β-glucuronide-linker drug conjugates
Ligand Drug conjugate compounds comprising a β-glucuronide-based linker and methods of using such compounds are provided. ...
10/18/2011
7824927Analyte detection using an active assay
Analytes using an active assay may be detected by introducing an analyte solution containing a plurality of analytes to a lacquered membrane. The lacquered membrane may be a membrane having at least one surface treated with a layer of polymers. The lacquered membran...
11/02/2010
7790472Fixed support for immobilizing biomolecules
The invention concerns a fixed support for immobilizing biomolecules, said support being covered, at least in some parts, with a polymer. The invention is characterized in that the polymer is an epoxy resin with functionality ranging between 4 and 15. The invention ...
09/07/2010
7790473Biofunctionalized quantum dots for biological imaging
Novel biofunctionalized quantum dots include a mercaptoalkanoic acid linked to the surface of a nanocrystalline core and a bio-functional group linked to the surface. Biofunctionalized quantum dots are made by a novel synthesis method. Biofunctionalized quantum dots...
09/07/2010
7749776Liquid flow assays utilising a combined detection and control zone
The invention relates to liquid flow assays widely applicable to target analytes, including haptens, which employ a detection zone which is a single combined analyte detection and control zone in a test strip or sheet and two labelled reagents with detectably distin...
07/06/2010
7572644Hydrogel copolymer, substrate coated with the copolymer, method of producing microarray using the copolymer, and microarray produced by the method
A novel hydrogel copolymer, a substrate coated with the copolymer, a method of producing a microarray using the copolymer, and a microarray produced by the method are provided. The use of the hydrogel copolymer makes efficient removal of protein and high integration...
08/11/2009
7423117Surface-functionalized carrier material and solid phase synthesis method
The invention concerns a novel surface-functionalized carrier material with a polymeric surface and at least one linker compound according to the general formula (I), which is covalently bound to the surface. In the formula, P indicates the polymeric surface; R...
09/09/2008
7419796Method of making a test device
The present invention relates to a method for making a test device for detecting or quantifying an analyte in a sample. This method involves contacting a membrane with a mixture including derivatized, marker-loaded liposomes, and substantially dehydrating the mixtur...
09/02/2008
7417021Biologically active conjugate of a biopolymer and therapeutic agent
A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a suitable carrier, has improved in vivo stability and activity, and can be t...
08/26/2008
7402381Method of immobilizing molecules onto a solid phase substrate and method of fabricating a biosensor using the method
Aspects of the invention can provide a method capable of easily realizing immobilization with the optimum density derived from a concentration control and without phase separation in coadsorption of a number of molecules. The immobilization method can include the st...
07/22/2008
7399642Fine particle film and producing method of the same
To provide fine particle films including fine particles which are arranged at a high density in a highly accurate and regular manner is enabled. The fine particle film is a fine particle film including a substrate and plural number of protein fine particles which ar...
07/15/2008
7399645Constrained cis-diol-borate bioconjugation system
The invention pertains to bioconjugation systems comprising sterically constrained cis-diols and borates. ...
07/15/2008
7396676Evanescent wave sensor with attached ligand
The invention in particular embodiments provides an evanescent wave sensor which includes a ligand bound to a sensor substrate via a NCYX linker moiety, as defined herein. Methods of making the subject evanescent wave sensors are also provided which include contacti...
07/08/2008
7393698Magnetic fine particles and process for producing the same
The present invention relates to magnetic fine particles having immobilized thereto a polymer having an upper critical solution temperature, and a process for producing the same, a method of separating or concentrating a microorganism, a method of purifying, detecti...
07/01/2008
7368296Solid phases optimized for chemiluminescent detection
Solid supports for chemiluminescent assays are provided. The solid support includes a plurality of probes covalently or physically attached to the support surface and a chemiluminescent enhancing moiety incorporated onto the surface or into the bulk of the support. ...
05/06/2008
7349590Polarization modulation interrogation of grating-coupled waveguide sensors
An optical interrogation system and a GCW sensor are described herein that are used to determine whether a biological substance (e.g., cell, molecule, protein, drug) is located in a sensing region of the GCW sensor. The optical interrogation system includes a light ...
03/25/2008
7344849Assay
The present invention relates to assay methods for the determination of cobalamin or vitamin B12 in a body fluid and in particular to assay methods for the metabolically active pool of cobalamin, comprising contacting a cell free sample of a body fluid wi...
03/18/2008
7338813Carrier particle latex for assay reagent and assay reagent
An objective of the invention is to provide a carrier particle latex for an assay reagent capable of assaying a biological sample at a wide range of the concentration in an immunoserological test and capable of being stored stably for a prolonged period, as well as ...
03/04/2008
7329492Methods for real-time single molecule sequence determination
A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a de...
02/12/2008
7329484Retentate chromatography and protein chip arrays with applications in biology and medicine
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by d...
02/12/2008
7312057Method for reducing binding of organic material to hydrophobic surfaces
Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying...
12/25/2007
7303750Methods to improve immunogenicity of antigens and specificity of antibodies
A method of improving specific immune response to small immunogens, haptens, has been developed by changing the linkage between the hapten and carrier being used for immunization. High affinity antibodies to cotinine have been produced using this method. Antibodies ...
12/04/2007
7300633Specimen collection container
The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ...
11/27/2007
7288416Ionic polymers and polymer-comprising substrates
An objective of the present invention is to provide ionic polymers that can provide for polymer-comprising substrates whose surfaces can stably and easily immobilize ligands such as sugar chains interacting with biological substances, in which the ligand portion exi...
10/30/2007
7285422Systems and methods for preparing and analyzing low volume analyte array elements
The invention provides methods for dispensing tools that can be employed to generate multi-element arrays of sample material on a substrate surface. The substrates surfaces can be flat or geometrically altered to include wells of receiving material. The tool can dis...
10/23/2007
7270959Specimen collection container
The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ...
09/18/2007
7255998High sensitivity immunoassay method
A method for detecting a cytokine in a biological fluid sample with a high sensitivity is provided. A time-resolved fluoroimmunoassay (TR-FIA) method including a step of forming on a solid phase a composite in which a cytokine is captured and which includes a fluore...
08/14/2007
7232690Method and device for detecting and isolating pharmacological compounds being contained in substance mixtures
A process for isolating and/or identifying at least one active chemical substance from a mixture of active and inactive chemical substances, is characterized by the steps: a) adding a target to said mixture and forming a complex of...
06/19/2007
7232688Systems and methods for preparing and analyzing low volume analyte array elements
Methods for dispensing tools that can be employed to generate multi-element arrays of sample material on a substrate surface. The resulting substrates are also provided. The substrates surfaces can be flat or geometrically altered to include wells of receiving mater...
06/19/2007
7229835Amine detection method and materials
A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the 1-hydroxybenzotriazole-6-carboxylic acid is direct...
06/12/2007
7229771Polyethylene glycol-derivatized biomolecules and their use in heterogeneous detection methods
The use of polyalkylene oxide modified reagents is disclosed in a method for the detection of an analyte or in suitable reagent kits for such methods. ...
06/12/2007
7217530Process for detecting PrP using a macrocyclic adjuvant ligand
A process for detecting the forms of the prion pathogens responsible for subacute, transmissible, spongiform encephalopathies, including a macrocyclic adjuvant ligand (AML), free or bound to a support, that is added to a biological sample capable of containing PrP
05/15/2007
7217512Reagent and method for attaching target molecules to a surface
The present invention provides a method and reagent composition for attachment of target molecules onto the surface of a substrate, such as microwell plates, tubes, beads, microscope slides, silicon wafers or membranes. In one embodiment, the method and composition ...
05/15/2007
7214530Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices
A biosensor includes a substrate with a layer of receptive material disposed thereon overlying a layer containing a photo-reactive agent. The receptive material is specific for an analyte of interest. A pattern of active and inactive areas of the receptive material ...
05/08/2007
7214388Degradable heterobifunctional poly(ethylene glycol) acrylates
A heterobifunctional poly(ethylene glycol) is provided having a hydrolytically degradable linkage, a first terminus comprising an acrylate group, and a second terminus comprising a target such as a protein or pharmaceutical agent or a reactive moiety capable of coup...
05/08/2007
7211645PRO268 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of ...
05/01/2007
7208299Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces
The present invention is directed to a composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces and hydrophobic coated surfaces. The composition is a biomolecule conjugated end-group activated polymer (EGAP). The biomolecu...
04/24/2007
7205161Polymer brushes for immobilizing molecules to a surface or substrate having improved stability
Sensors for determining the presence and concentration of biomolecules in a biological sample are provided in the form of polymer brushes, which comprise a substrate having a surface modified with a hydrophobic polymer segment, attached to which is a water-dispersib...
04/17/2007
7198893DNA diagnostics based on mass spectrometry
Fast and highly accurate mass spectrometry-based processes for detecting a particular nucleic acid sequence in a biological sample are provided. Depending on the sequence to be detected, the processes can be used, for example, to diagnose a genetic disease or chromo...
04/03/2007
7195908Supports treated with triamine for immobilizing biomolecules
Supports for immobilizing molecules, particularly biomolecules, methods of making such supports, kits, and biomolecular hybridization assay devices are disclosed. The methods, supports and devices include forming a triamine layer on at least a portion of a substrate...
03/27/2007
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