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| Number | Title | Issue Date |
| 7867785 | Carrier particle latex for assay reagent and assay reagent An objective of the invention is to provide a carrier particle latex for an assay reagent capable of assaying a biological sample at a wide range of the concentration in an immunoserological test and capable of being stored stably for a prolonged period, as well as ... | 01/11/2011 |
| 7659125 | Latex reagent for adiponectin analysis and method of adiponectin analysis A latex reagent for analyzing adiponectin, comprising a suspension of latex particles carrying a substance which specifically binds to adiponectin, is disclosed. Further, a method for analyzing adiponectin, comprising (1) obtaining a biological liquid possibly conta... | 02/09/2010 |
| 7494824 | Interactive system for presenting and eliminating substances An interactive system is provided with at least one active surface of plastic from monomers containing at least one structural element derived from a carbon dioxide (A), and at least one substance associated to a linker with at least one structural element (B) capab... | 02/24/2009 |
| 7442553 | Method for determining the amount of the maleimidyl groups of a particle A method for quantitatively determining the amount of maleimidyl groups on a polymer fine particle containing at least maleimidyl groups, by allowing a fluorescent material having an SH group to react with the maleimidyl groups and determining the amount of maleimid... | 10/28/2008 |
| 7423155 | N-sulfonyldicarboximide containing tethering compounds Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The s... | 09/09/2008 |
| 7402381 | Method of immobilizing molecules onto a solid phase substrate and method of fabricating a biosensor using the method Aspects of the invention can provide a method capable of easily realizing immobilization with the optimum density derived from a concentration control and without phase separation in coadsorption of a number of molecules. The immobilization method can include the st... | 07/22/2008 |
| 7393696 | Bovine pregnancy test This invention provides bovine pregnancy test methods and devices. The test is also suitable for other ruminant and/or ungulate animals. Antigens from Group A (early pregnancy antigens), and/or Group B (mid-pregnancy antigens), and Group C (early, mid- and late preg... | 07/01/2008 |
| 7393698 | Magnetic fine particles and process for producing the same The present invention relates to magnetic fine particles having immobilized thereto a polymer having an upper critical solution temperature, and a process for producing the same, a method of separating or concentrating a microorganism, a method of purifying, detecti... | 07/01/2008 |
| 7390461 | Broad spectrum optically addressed sensor The present invention relates to a sensor for detecting chemical, biological, biochemical or other environmental stimuli, and includes a plurality of colloidal particles having chemical receptors bound to each particle's surface, wherein when a target stimulus is di... | 06/24/2008 |
| 7384779 | Porous substrate plates and the use thereof A substrate plate or device adapted for use with biological or chemical assays is disclosed. The device may take the form of a multi-well plate having a three-dimensional, porous layer as part of a support surface within each well for immobilizing probe species. The... | 06/10/2008 |
| 7381552 | Macroporous material in the form of plastic pearls The invention relates to a macroporous plastics bead material with an average particle diameter from 10 to 1000 μm, containing a copolymer of a) 5-60 wt. % vinylically polymerizable monomers with a water solubility of at least 1% at 20° C., b) 1-40 wt. % vinylical... | 06/03/2008 |
| 7371562 | Guided mode resonant filter biosensor using a linear grating surface structure Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. ... | 05/13/2008 |
| 7371584 | Multi-functional and configurable assay Novel magnetic assay methods and systems. According to a preferred embodiment, a chromatographic medium is provided that is designed to be contacted with a test solution having activated magnetic particles such that the solution flows bilaterally thereacross. A magn... | 05/13/2008 |
| 7368296 | Solid phases optimized for chemiluminescent detection Solid supports for chemiluminescent assays are provided. The solid support includes a plurality of probes covalently or physically attached to the support surface and a chemiluminescent enhancing moiety incorporated onto the surface or into the bulk of the support. ... | 05/06/2008 |
| 7364918 | Colorimetric sensors constructed of diacetylene materials Colorimetric sensors comprising a receptor incorporated within polydiacetylene assemblies to form a transducer capable of indicating a color change when contacted with an analyte are disclosed. Methods of using the colorimetric sensor and a kit for the colorimetric ... | 04/29/2008 |
| 7355079 | Thyronamine derivatives and analogs and methods of use thereof Thyronamine derivatives and analogs, methods of using such compounds, and pharmaceutical compositions containing them are disclosed. Methods of preparing such compounds are also disclosed. ... | 04/08/2008 |
| 7351838 | N-sulfonyldicarboximide containing tethering compounds Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The s... | 04/01/2008 |
| 7348157 | Immunoassay A method for detection and/or quantification of cardiac troponin I (cTnI) in a sample derived from an individual's blood, the method being based on a sandwich immunoassay employing at least two capture antibodies and at least one tracer antibody, in which a first ca... | 03/25/2008 |
| 7344848 | Methods for determining adequacy of heat processing of a cooked meat sample Monoclonal antibodies are provided which bind to heat-treated proteins of meats. The antibodies are useful in detecting the presence of an exogenous meat in a cooked or raw meat sample. Furthermore, the antibodies can be used to determine the end point temperature o... | 03/18/2008 |
| 7338813 | Carrier particle latex for assay reagent and assay reagent An objective of the invention is to provide a carrier particle latex for an assay reagent capable of assaying a biological sample at a wide range of the concentration in an immunoserological test and capable of being stored stably for a prolonged period, as well as ... | 03/04/2008 |
| 7329484 | Retentate chromatography and protein chip arrays with applications in biology and medicine This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by d... | 02/12/2008 |
| 7326578 | Urine assay for ovarian reserve It has been found that a urine test for ovarian reserve can be provided which is equivalent in sensitivity to current laboratory methods which determine ovarian reserve based on FSH levels in serum. A lateral flow device for indicating ovarian reserve is disclosed. ... | 02/05/2008 |
| 7327454 | Method and apparatus for detecting biomolecular interactions Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light... | 02/05/2008 |
| 7319032 | Non-sugar sweeteners for use in test devices The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having non-sugar sweeteners effectively enhance chromatographic detection methods by providing componen... | 01/15/2008 |
| 7314845 | Supported catalyst systems The present invention relates to a supported catalyst system. The supported catalyst of the present invention comprises an inorganic support having attached to at least one surface thereof non-acidic, hydrophilic, hydroxyl-containing organic R10 groups ha... | 01/01/2008 |
| 7314749 | Method and apparatus for assay based on light diffraction The present invention relates to a method and apparatus for detecting analytes in a medium, and more particularly the present invention relates to an assay based on light diffraction which appears or changes upon the binding of analytes to their specific receptors l... | 01/01/2008 |
| 7312057 | Method for reducing binding of organic material to hydrophobic surfaces Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying... | 12/25/2007 |
| 7312090 | Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor Methods are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also relates to optical devices. ... | 12/25/2007 |
| 7309723 | Redox polymer nanoparticles The invention provides nanoparticles comprising one or more redox-active species, methods of making such nanoparticles, and methods for using such nanoparticles, for example, as diagnostic agents for the detection of various analytes. ... | 12/18/2007 |
| 7300803 | Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor Methods are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also relates to optical devices. ... | 11/27/2007 |
| 7301628 | Method and apparatus for detecting biomolecular interactions Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light... | 11/27/2007 |
| 7292336 | Method and instrument for detecting biomolecular interactions Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An instrument system for detecting a biochemical interaction on a biosensor. The system includes an array of... | 11/06/2007 |
| 7291477 | Method and device for detection A method and kit for detecting Trichomonas vaginalis infection in a human subject are disclosed. In the method, a body-fluid sample such as a vaginal swab sample or urine is obtained from the subject and contacted with an antibody specific against a Tricho... | 11/06/2007 |
| 7288415 | Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules The present invention provides imprint compositions useful for capturing, isolating, detecting and/or quantifying macromolecules in a sample, methods of making and using the same. Generally, the imprint compositions comprise a matrix material defining an imprint of ... | 10/30/2007 |
| 7285424 | Membrane-based assay devices A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes a self-calibrated magnetic binding assay format (e.g., sandwich, competitive, etc.) that includes detection probes capable o... | 10/23/2007 |
| 7264938 | Method of detecting native proBNP The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a h... | 09/04/2007 |
| 7264939 | Method of detecting native proBNP The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a h... | 09/04/2007 |
| 7247489 | Ion-detecting microspheres and methods of use thereof This invention provides methods of using ion-detecting microspheres containing an ionphore and a chromoionphore in clinical laboratory instrumentation such as flow cytometry for sample analysis. In one embodiment, the microspheres are contacted with a flowing stream... | 07/24/2007 |
| 7247500 | Reduction of the hook effect in membrane-based assay devices A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes a chromatographic zone on which is disposed a plurality of microporous particles. The chromatographic zone can effectively r... | 07/24/2007 |
| 7238536 | Controlled transport through multiple reversible interaction point membranes A membrane comprising two or more macromolecules that interact via multiple reversible physical interaction points (MRIPM). The membrane further comprises a chemical species A, which interacts selectively or nonselectively with the MRIPM; and a chemical species B, w... | 07/03/2007 |
