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Class 436/520 - Red blood cell


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Subject matter in which the carrier is a red blood cell.
No. of patents: 234
Last issue date: 09/28/2010


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NumberTitleIssue Date
7803637Compositions and methods for treatment of neoplastic disease
The present invention comprises the use of sickle cells or sickle cell precursors loaded with a therapeutic agent that localizes in tumors and induces a tumoricidal response. ...
09/28/2010
7390631Diagnosis and monitoring of systemic lupus erythematosus and of scleroderma
Methods for diagnosing and monitoring systemic lupus erythematosus (SLE) or scleroderma by determining, in a blood sample from the individual being diagnosed or monitored, complement component C4d deposited on surfaces of red blood cells in the sample, and optionall...
06/24/2008
7300804Method and apparatus for controlling the uniform smearing of a biological liquid over a substrate
A method and apparatus for controlling the processing of a liquid sample, e.g., a blood sample, based on a measurement related to the sample's ability to coat a surface against which the sample is brought into contact while being routinely transported. Preferably, t...
11/27/2007
7247501Imaging and targeting tumors using sickle cells
According to the present invention, there is provided a delivery vehicle including sickle red blood cells carrying a moiety. The moiety can be any type of diagnostic or therapeutic agent. The present invention further provides for a method of diagnosing systemic hyp...
07/24/2007
7160686Method for producing a specific antiserum against the universal tumorous antigen and method for diagnosing malignant tumours using said antiserum
The present invention pertains to the field of medicine and may be used for producing a specific antiserum as well as for carrying out immunological diagnoses of malignant tumours. This method for producing an antiserum involves sampling an embryo at the foetal stag...
01/09/2007
7060453Method and kit for the determination of analyte concentration in blood
A method is provided for determining the level of an analyte in the blood of an individual based on determination of the level of the same analyte in non-blood sample (e.g. urine, saliva and hair) obtained from the individual. The non-blood sample contains red blood...
06/13/2006
7052831Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
The present invention provides a method and device for conducting a rapid in vitro enzyme immunoassay test for the direct and qualitative detection of two or more viral antigens from specimens of symptomatic patients. The method for immunoassay of viral antigens is ...
05/30/2006
7044919Test methods, devices and test kits
A method for determining the time of maximum fertility in the mammalian ovulation cycle, for the purpose of assisting conception, wherein testing is conducted over a period of days in the current ovulation cycle on samples of body fluid obtained from an individual h...
05/16/2006
7022529Particles for diagnostic and therapeutic use
Methods, compositions and kits are disclosed. The compositions are light emitting and comprise a polymeric matrix having dissolved therein a photoactive compound. The composition has the characteristic that, after activation of the photoactive compound, the rate of ...
04/04/2006
6955889Simultaneous determination of forward and reverse ABO blood group
Simultaneous forward and reverse blood group testing is described using both a visual detection system and a fluorescent based labeling and detection system. Forward and reverse tests could be performed separately, but A and B agglutinates can be detected and discri...
10/18/2005
6911178Rh blood group antigen compositions and methods of use
Disclosed are novel protein and peptide compositions comprising soluble and bound forms of immunologically-active blood group antigens including mammalian Rh antigens. In preferred embodiments methods for the isolation and purification of serologically-active human ...
06/28/2005
6878811Substance with antithrombotic activity and method for detecting glycokallidin
A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric prot...
04/12/2005
6858439Compositions and methods for separation of moieties on chips
The present invention recognizes that separation of components of a sample facilitate, and are often necessary for, sample analysis. Dielectrophoretic separation provides an efficient, reliable, nondisruptive, and automatable method for the separation of moieties in...
02/22/2005
6830895Method and kit for typing feline blood
The present invention relates to a kit for determining feline blood type, wherein the kit includes a mixture comprised of a first monoclonal antibody and a second monoclonal antibody, wherein both antibodies recognize feline blood group specific A antigens. The pres...
12/14/2004
6825000Immunoassay reagent and immunoassay method
An immunoassay reagent is obtained whereby a microscale substance such as an antigen or antibody can be assayed at a high sensitivity, and whereby a need to separate a reacted substance, e.g., an immunoreacted substance, from an unreacted substance can be eliminated...
11/30/2004
6821790Methods and apparatus for separation of biological fluids
A method of separating a cell-containing sample into a substantially cell-depleted portion, and a cell-containing portion comprising at least one of a stem cell, a lymphocyte, and a leukocyte comprises a step in which the sample is received in a vessel with at least...
11/23/2004
6703248Particles for diagnostic and therapeutic use
Methods, compositions and kits are disclosed. The compositions are light emitting and comprise a polymeric matrix having dissolved therein a photoactive compound. The composition has the characteristic that, after activation of the photoactive compound, t...
03/09/2004
6686158Electronically-indexed solid-phase assay for biomolecules
Disclosed are materials and methods for detecting biomolecules in samples employing transponders associated with the bead(s) used as the solid phase in the assay, and information pertinent to the assay is encoded on the transponders memory elements. A ded...
02/03/2004
6677123Process for detecting increased risk of fetal chromosomal abnormality
An increased risk of a fetal chromosomal abnormality, for example, fetal Down syndrome can be detected by separating or discriminating ଱-fetoproteins present in the body fluid of a pregnant woman, and measuring the proportion of one or more of the &...
01/13/2004
6673629Neutralization of polycations in a chromatographic device for whole blood use
A chromatography assay device and method for use with whole blood samples utilizing a red blood cell separating agent to aggregate red blood cells and permit plasma or serum to flow by capillary action and a neutralizing agent to neutralize any effects th...
01/06/2004
6627404Methods for improving the recovery of troponin I and T in membranes, filters and vessels
A method to facilitate recovery troponin I and/or troponin T from a sample comprising addition of troponin C to the sample or to a surface from which the troponin I and/or troponin T are recovered....
09/30/2003
6544751Methods of harvesting rare cells from blood products
The present invention provides methods of harvesting rare cells from blood products and/or obtaining products of the rare cells. The method includes contacting a blood product containing rare cells with a porous medium, and selectively retaining rare cell...
04/08/2003
6534279Reagent and method for the permeabilization and identification of erythrocytes
A process for permeabilizing erythrocytes in which the erythrocytes are subjected successively to the action of (a) a fixing agent containing an aliphatic aldehyde and oligosaccharide, (b) a permeabilizing agent containing a detergent and an oligosaccharide, kit fo...
03/18/2003
6534008In situ heat induced antigen recovery and staining apparatus and method
An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of staining the biological sample on the microscope slide are ...
03/18/2003
6475748Method for differentiating human peripheral blood granulocytes
Disclosed is a method for differentiating human peripheral blood granulocytes which comprises cultivating the granulocytes in the presence of an interferon and acting an immune complex on said granulocytes in the presence of a chemiluminescent substance, ...
11/05/2002
6376187Electronically-indexed solid-phase assay for biomolecules
Disclosed are materials and methods for detecting biomolecules in samples employing transponders associated with the bead(s) used as the solid phase in the assay, and information pertinent to the assay is encoded on the transponders memory elements. A ded...
04/23/2002
6331395Prenatal diagnostic methods
A method of identifying embryonic or fetal red blood cells in a sample containiing maternal blood cells and embryonic or fetal red blood cells or both, the method comprising determining which cell or cells contain or express an adult liver component. A me...
12/18/2001
6303390Method for antigen and antibody determination in bloodgroup serology
Method and test kit for assaying in a sample an analyte which is a bloodgroup antigen present on erythrocytes or an antibody binding to such a bloodgroup antigen. To that end, the sample is treated with a reagent containing a binding partner for the analy...
10/16/2001
6291249Method using an apparatus for separation of biological fluids
A cell containing sample is separated into a cell containing portion and a substantially cell depleted portion, by mixing the sample with particles to produce a cell containing network, and separating the network from the remaining substantially cell depl...
09/18/2001
6284459Solid support matrices with memories and combinatorial libraries therefrom
Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and...
09/04/2001
6280958Rh blood group antigen compositions and methods of use
Disclosed are novel protein and peptide compositions comprising soluble and bound forms of immunologically-active blood group antigens including mammalian Rh antigens. In preferred embodiments methods for the isolation and purification of serologically-ac...
08/28/2001
6258607Indirect agglutination immunoassay and apparatus therefor
An indirect agglutination immunoassay includes the steps of providing, in a container, an immunoassay system comprising a test sample containing a desired analyte, and a reagent composed of magnetic particles or magnetic-material containing particles cont...
07/10/2001
6219584Method and system for determining an effective amount of light energy to delivery to fluids having targets for the light energy
Systems and methods for determining an effective amount of light energy to deliver to fluids, particularly fluids having target and non-target materials. The systems and methods specifically relate to phototherapy and photopheresis systems where an effect...
04/17/2001
6204068Biospecific assay method
This invention is thus related to a biospecific multiparameter assay employing single molecule detection. In particular, this invention is related to a new method for determination of several different biomolecules simultaneously in the same reaction solu...
03/20/2001
6184011Method of releasing solid matrix affinity adsorbed particulates
A method of releasing particulates from a solid matrix is provided. The method is effected adding to the solid matrix a degrading enzyme capable of degrading the solid matrix, to thereby release the particulates from the solid matrix....
02/06/2001
6143575Heterogeneous immunoassay using a precipitable solid phase
The invention relates to a method for carrying out heterogeneous immunoassays, in particular to a method for separating a coated solid phase from a liquid phase by means of precipitation and subsequent centrifugation, with a detectable activity remaining ...
11/07/2000
6132981Method for detecting a mammal's prior exposure to radiation or radiomimetic agents
The present invention is directed to a method for detecting a mammal's prior exposure to radiation or radiomimetic agents. Labeled antibodies are employed to determine the quantity of transferrin receptors on the red blood cells of the mammal. The quantit...
10/17/2000
6114179Method and test kit for detecting antigens and/or antibodies
A suspension of inert particles is prepared in an aqueous solution, to which an antibody or an antigen and a carrier-bound antigen or antibody, respectively, are added in any desired order. After centrifuging, the positive, weakly positive, or negative re...
09/05/2000
6063584Anticoagulant test
The present invention is a method for identifying a patient at risk to developing fibrinogen receptor antagonist-induced thrombocytopenia which comprises incubating patient plasma with a GPIIb/IIIa receptor:GPIIb/IIIa receptor antagonist complex to form a...
05/16/2000
6046003Method of determining the sequence of nucleic acids employing solid-phase particles carrying transponders
A method is described for determining the sequence of nucleic acids. The method employs small solid phase particles having transponders, with a primary layer of an oligonucleotide of known sequence attached to the outer surface of the particle. A read/wri...
04/04/2000
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