Did You Know...
...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 7390675 | Multi-functional and configurable assay Novel magnetic assay methods and systems. According to a preferred embodiment, a chromatographic medium is provided that is designed to be contacted with a test solution having activated magnetic particles such that the solution flows bilaterally thereacross. A magn... | 06/24/2008 |
| 7378270 | Device for analyte measurement A biochemical analysis instrument for multiple fluid analyses includes a housing. A sensor for sensing a reaction is disposed in the housing. An aperture is formed in the housing. A test tape housing area is formed in the housing, and the sensor is disposed to selec... | 05/27/2008 |
| 7354733 | Method for sorting and separating living cells We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a... | 04/08/2008 |
| 7179639 | Thermal strip thermocycler This is a self-contained disposable thermal cycler device in which target sequence is amplified as the samples passes over a grid of alternating temperature and then at the completion of the reaction, the amplified material is captured by probes complementary to the... | 02/20/2007 |
| 7179612 | Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality A method for diagnosing a condition of a patient involves the steps of (a) adding one or more reagents to a test sample from a patient, the test samples comprising at least part of a blood sample from the patient, in order to cause formation of a complex comprising ... | 02/20/2007 |
| 7160686 | Method for producing a specific antiserum against the universal tumorous antigen and method for diagnosing malignant tumours using said antiserum The present invention pertains to the field of medicine and may be used for producing a specific antiserum as well as for carrying out immunological diagnoses of malignant tumours. This method for producing an antiserum involves sampling an embryo at the foetal stag... | 01/09/2007 |
| 7118900 | Directed assembly of functional heterostructures The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies of polymer-microparticle composites including the AC electric field-mediated assembly of patterned, self-supporting organic (polymeric) f... | 10/10/2006 |
| 6958219 | Method for detecting a gram-negative bacterial autoinducer molecule The present invention relates to an immunogenic conjugate comprising a carrier molecule coupled to an autoinducer of a Gram negative bacteria. The immunogenic conjugate, when combined with a pharmaceutically acceptable carrier, forms a suitable vaccine for mammals t... | 10/25/2005 |
| 6893546 | Method for separating a chemical or biological compound in a mixture of similar compounds by diffusion in a medium such as a gel A method for separating a chemical or biological compound present in a mixture of similar compounds by diffusion in a medium, the method comprising reacting the compounds of the mixture with a component (P) present in the medium to obtain products (Qi), w... | 05/17/2005 |
| 6887712 | Methods and compositions to lower plasma cholesterol levels A method is disclosed for determining whether a compound binds to a lipoprotein such as LDL or VLDL in a manner which will lower plasma cholesterol. The method provided includes assessing the ability of the compound to form a complex with the lipoprotein, and then d... | 05/03/2005 |
| 6824988 | Method and compositions for use in diagnosing and characterizing chronic immune disease Methods are provided for diagnosing and/or characterizing chronic immune disease activity in a subject. In the subject methods, a sample is obtained from a subject suspected of having or known to have a chronic immune disease. The sample is then assayed for the pres... | 11/30/2004 |
| 6762057 | Separation apparatus including porous silicon column A sample separation apparatus including a porous, or rough, capillary column. The porous capillary column includes a matrix which defines pores, and may be formed from a material such as porous silicon. Alternatively, the capillary column may have a rough surface of... | 07/13/2004 |
| 6706539 | Enzyme substrate delivery and product registration in one step enzyme immunoassays One-step enzyme immunoassays in which enzyme-antibody conjugate or label and enzyme substrate are separated until separation of bound and free enzyme conjugate or label is complete. This separation is accomplished by using variable flow paths, immobilization of subs... | 03/16/2004 |
| 6696264 | Method and apparatus for detection of multiple biological materials with a heterogeneous antibody mixture The present invention relates to bioassay materials useful for the detection of toxic substances and, more particularly, to packaging materials for food and other products, along with methods for their manufacture and use. The invention provides a unique ... | 02/24/2004 |
| 6599708 | Immunologically based strip test utilizing ionophore membranes A testing apparatus 10 having an absorbent matrix 12, including a membrane 14 which contains a plurality of counter-ions 16. Chromionophore (or fluorionophore)s 18 and affinophores 22 compete to carry ions into the membrane 14 and neutralize the charge of... | 07/29/2003 |
| 6596501 | Method of diagnosing autoimmune disease The present invention relates to diagnostic applications. For autoimmune diseases more particularly, it is demonstrated herein that individuals with SLE, APLA, MCDS and PSS have antibodies that are specific for SR proteins. Thus, in particular aspects the... | 07/22/2003 |
| 6524866 | Capillary electrophoretic method to detect target-binding ligands and to determine their relative affinities The invention relates to capillary electrophoretic methods for detecting ligands or hit compounds that can bind to a selected target at or above a selected binding strength. The method allows one to rank various ligands based on their relative affinity, i... | 02/25/2003 |
| 6440749 | Method of treating certain indications associated with hyperglycemia The present invention relates to compositions and methods for inhibiting and reversing nonenzymatic cross-linking (protein aging). Accordingly, compositions are disclosed which comprise an agent capable of inhibiting the formation of advanced glycosylatio... | 08/27/2002 |
| 6410251 | Method for detecting or assaying target substance by utilizing oxygen electrode A method for detecting or assaying one constituting member in a specific binding pair, for example, the antigen in an antigen/antibody pair, by utilizing specific binding such as binding between an antigen and an antibody, together with redox reaction for... | 06/25/2002 |
| 6379908 | Method and apparatus for selective biological material detection The present invention relates to bioassay materials useful for the detection of toxic substances and, more particularly, to packaging materials for food and other products, along with methods for their manufacture and use. The invention provides a unique ... | 04/30/2002 |
| 6376204 | Method and apparatus for selective biological material detection The present invention relates to bioassay materials useful for the detection of toxic substances and, more particularly, to packaging materials for food and other products, along with methods for their manufacture and use. The invention provides a unique ... | 04/23/2002 |
| 6365415 | Method for characterization and quality control of porous media The present invention provides a method to characterize, optimize, and control the quality and production of hydrogel media. Additionally, the present invention provides a method for determining the size, size distribution, and spatial distribution of the... | 04/02/2002 |
| 6306611 | Immunologically based strip test utilizing ionophore membranes A testing apparatus 10 having an absorbent matrix 12, including a membrane 14 which contains a plurality of counter-ions 16. Chromionophore (or fluorionophore)s 18 and affinophores 22 compete to carry ions into the membrane 14 and neutralize the charge of... | 10/23/2001 |
| 6306642 | Enzyme substrate delivery and product registration in one step enzyme immunoassays One-step enzyme immunoassays in which enzyme-antibody conjugate or label and enzyme substrate are separated until separation of bound and free enzyme conjugate or label is complete. This separation is accomplished by using variable flow paths, immobilizat... | 10/23/2001 |
| 6130099 | Method of comparing peak representations, specifically western blot or dot blot strips The slope lines of the peak lines are determined for a reference specimen and a test specimen and then compared with one another to analyze peak lines independently of the background. Preferably a minimum amplitude of a slope line is established with a th... | 10/10/2000 |
| 6103537 | Capillary assays involving separation of free and bound species The present invention concerns methods for masking inhomogeneity of a member of a specific binding pair (sbp) employed in a capillary electroseparation. The method comprises binding the sbp member to synthetic particles that become localized during capill... | 08/15/2000 |
| 6051388 | Method and apparatus for selective biological material detection The present invention relates to bioassay materials useful for the detection of toxic substances and, more particularly, to packaging materials for food and other products, along with methods for their manufacture and use. The invention provides a unique ... | 04/18/2000 |
| 6048703 | Methods for detecting cell apoptosis Methods for the biochemical and immunohistochemical detection of cell apoptosis are described. The methods utilize the detection and measurement of polypeptide fragments generated during apoptosis. Conditions associated with apoptosis may be detected by t... | 04/11/2000 |
| 6046008 | Immunologically based strip test utilizing ionophore membranes A testing apparatus 10 having an absorbent matrix 12, including a membrane 14 which contains a plurality of counter-ions 16. Chromoionophore (or fluorionophore)s 18 and affinophores 22 compete to carry ions into the membrane 14 and neutralize the charge o... | 04/04/2000 |
| 5989921 | Test device and method for colored particle immunoassay Disclosed is a test cell and a method for detection of a preselected ligand in a liquid sample such as a body fluid. The test cell includes an elongate outer casing which houses an interior permeable material capable of transporting an aqueous solution an... | 11/23/1999 |
| 5879881 | Solid phase system for use in ligand-receptor assays A solid phase system for use in ligand-receptor assays, particularly immunoassays using monoclonal antibodies, is disclosed. The solid phase system comprises a porous matrix in which microspheres, bound with a receptor capable of capturing a target ligand... | 03/09/1999 |
| 5856201 | Methods of detection using a cellulose binding domain fusion product A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewis... | 01/05/1999 |
| 5843680 | Differential separation assay methods and test kits Analytes can be detected from among closely related substances by reacting the analyte in a test sample with a labeled binding agent which specifically binds to the analyte to form a complex. The labeled binding agent is supplied in excess, and the comple... | 12/01/1998 |
| 5837474 | Immunological method for the detection of malignant tumors and kit for performing the method A method of detecting malignant tumors and determining their mass includes withdrawing fresh blood and/or serum samples from the patient. The blood or serum sample is then stabilized. The tumor determination is obtained from a shift in the ratio of at lea... | 11/17/1998 |
| 5714389 | Test device and method for colored particle immunoassay Disclosed is a test cell and a method for detection of a preselected ligand in a liquid sample such as a body fluid. The test cell includes an elongate outer casing which houses an interior permeable material capable of transporting an aqueous solution an... | 02/03/1998 |
| 5656503 | Test device for detecting analytes in biological samples An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as plastics materials, containing a dry porous carrier (510) which communicates indirectly with the ... | 08/12/1997 |
| 5552288 | Chromogen agar color reactive test sheet A moist unitary non-laminar chromogen agar color reactive test sheet for use in a simplified enzyme-linked immunosorbent assay (ELISA) for the diagnosis of viral, fungal, bacterial and parasitic diseases. The diagnostic test is designed for use in non-lab... | 09/03/1996 |
| 5470702 | HIV-2 transmembrane glycoprotein homodimer (gp 80) Character of the envelope transmembrane protein of human immunodeficiency virus type 2 (HIV-2) was carried out using murine polyclonal and monoclonal antibodies or patient sera specific for HIV-2 proteins. A 80-Mr glycoprotein (gp80) was produced in HIV-2... | 11/28/1995 |
| 5462853 | Detection of components of RNA viral glycoproteins using a mannose-specific lectin binding assay Anti-viral material comprising a mannose-specific lectin obtained from a bulb of the plant family Amaryllidaceae, for example Narcissus pseudonarcissus, and the use of this material to produce a medicament and a vaccine. The material is effective against ... | 10/31/1995 |
| 5436129 | Process for specimen handling for analysis of nucleic acids A process for handling a biological specimen for the analysis of nucleic acid sequences wherein the biological specimen is immobilized within a carrier device for controlled temperature conditions and the sequential addition of fluid treatments. The fluid... | 07/25/1995 |
